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READERS OPINION
Eat as much as you burn - a good diet and eating less should be more important than an intense exercise program for decreasing morbidity and mortality
Mustafa CakarI,
Corresponding author
drmustafacakar@gmail.com

Tel.: 90 312 3044015
, Sevket BaltaII, Sait DemirkolII, Omer KurtI, Hakan SarlakI, Zekeriya ArslanII
I Gulhane Medical Academy, Department of Internal Medicine, Ankara/Turkey
II Gulhane Medical Academy, Department of Cardiology, Ankara/Turkey
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="para10" class="elsevierStylePara elsevierViewall">Dear Editor&#44;</p><p id="para20" class="elsevierStylePara elsevierViewall">We read the article &#8221;The effects of exercise modalities on adiposity in obese rats&#8221; written by Guilherme Fleury Fina Speretta et al&#46; with great interest &#40;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#41;&#46; The authors concluded that both of the examined exercise modalities improved lipid profile&#44; adiposity and obesity-associated inflammation in rats&#44; suggesting their use as an alternative to control the deleterious effects of a high-fat diet in humans &#40;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#41;&#46; We thank the authors for their contribution of such a well-designed and well-presented study&#46; We believe that these findings will encourage further studies on obesity and the therapeutic role of diet&#46; In the aging and increasingly obese population worldwide&#44; this study deserves to be emphasized in terms of these current needs&#46;</p><p id="para30" class="elsevierStylePara elsevierViewall">Hyperlipidemia and obesity are strongly associated with the development of atherosclerosis&#44; and coronary artery disease&#44; cerebrovascular accidents and peripheral vascular disease are of particular clinical importance &#40;<a class="elsevierStyleCrossRef" href="#bib2">2</a>&#44;<a class="elsevierStyleCrossRef" href="#bib3">3</a>&#41;&#46; Success in decreasing serum lipid levels and obesity has led to successful decreases in patient morbidity and mortality &#40;<a class="elsevierStyleCrossRef" href="#bib4">4</a>&#41;&#46; Lifestyle changes and exercise are important and&#44; additionally&#44; antihyperlipidemic drugs can successfully reduce the incidence of atherosclerosis and related diseases&#46; It is well known that nearly one hundred patients must be treated to protect only one from any atherosclerotic event &#40;<a class="elsevierStyleCrossRef" href="#bib5">5</a>&#41;&#46; Therefore&#44; investigators should work to identify new drugs&#44; treatment approaches&#44; diet therapies and other modalities to decrease serum lipid levels and obesity and subsequently lower the expected mortality and morbidity of these patients&#46;</p><p id="para40" class="elsevierStylePara elsevierViewall">The present study was primarily conducted in three exercise groups of mice&#44; which were divided into animals receiving a normal diet or a high-fat diet&#46; It was clear that the high-fat diet led to higher visceral adiposity&#46; A statistically significant decrease occurred after swimming and high-resistance exercise in animals fed a high-fat diet&#46; However&#44; this decrease was not as large as the increase in adiposity caused by the high-fat diet and&#44; after intense exercise&#44; the weight of the animals fed a high-fat diet did not normalize to that of the normal diet control groups&#46; Resistance training led to lower amounts of adipose tissue compared to swimming&#46; Animals with sedentary life conditions fed the low-fat diet clearly had the lowest visceral adiposity&#46; We believe that the relative failure of the success of intense exercise in the swimming and resistance training groups should be discussed in future studies&#46; Additionally&#44; this result suggests that a good diet and lower caloric intake may be more important than an intense exercise program for decreasing morbidity and mortality&#46;</p><p id="para50" class="elsevierStylePara elsevierViewall">However&#44; the obesity induced in rats fed a high-fat diet and submitted to exercise programs may differ from some acquired and hereditary types of obesity observed in humans&#46; The physiologic effects and pathways involved in acquired and hereditary types of obesity may differ&#44; and these differences may affect the success of treatment&#46; We believe that the study results should be evaluated in these respects&#46;</p></span>"
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Article information
ISSN: 18075932
Original language: English
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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos