Sacrococcygeal pilonidal disease: analysis of previously proposed risk factors

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The disease frequently occurs as a chronic infection of the skin in the region of the buttock crease. SPD was first described by Hodges in 1880 and later, in 1833, was described by Herbert Mayo as a hair-containing sinus.<a class="elsevierStyleCrossRef" href="#bib2">2</a> Mayo’s findings were of a characteristic epithelial track (the sinus) that generally contains hair and is located in the skin of the natal cleft. The condition was commonly diagnosed in jeep drivers during the Second World War, which led to it being known as “jeep disease.”<a class="elsevierStyleCrossRef" href="#bib3">3</a> Although not as common, pilonidal disease may occur in other body parts, such as the clefts between the fingers of barbers or hairdressers.<a class="elsevierStyleCrossRef" href="#bib4">4</a>For a long time, the cause of SPD has been a matter of debate. Until the second half of the 20th century, SPD was thought to be secondary to a congenital remnant of an epithelial-lined tract of postcoccygeal epidermal cell rests or vestigial scent cells. A variety of explanations have supported the congenital theory. Some authors have suggested that the persistence of a caudal remnant of the neural canal forms small cysts, which cause SPD.<a class="elsevierStyleCrossRef" href="#bib5">5</a> Another hypothesis for SPD provides that SPD is the result of a formation of dermal inclusions by the cystic changes of sequestered epithelial rests.<a class="elsevierStyleCrossRef" href="#bib6">6</a> Excessive involution of the human tail has been accused of attracting skin into a subcutaneous area and results in an epithelium-lined tract.<a class="elsevierStyleCrossRef" href="#bib7">7</a> SPD is now, however, widely accepted as an acquired disorder. SPD is more common in men and in hirsute people.<a class="elsevierStyleCrossRef" href="#bib1">1</a> It usually occurs after puberty, and a linkage between the disease and various occupations has been demonstrated.<a class="elsevierStyleCrossRef" href="#bib1">1</a> In addition, there is a high recurrence rate of SPD after surgical excision. These factors argue against the validity of the congenital theory to explain SPD. Further, congenital tracts do not contain hair and are lined by cuboidal epithelium.<a class="elsevierStyleCrossRef" href="#bib8">8</a>Male gender, obesity, occupations or sports requiring sitting, a deep natal cleft, excessive body hair, stiff or coarse hair, poor body hygiene and excessive sweating are described as the primary risk factors for SPD.<a class="elsevierStyleCrossRef" href="#bib9">9</a> However, there is a noted lack of prospective studies in the literature that analyze and confirm these risk factors. There are only a few studies evaluating risk factors for SPD, and they are generally focused on the role of obesity.<a class="elsevierStyleCrossRefs" href="#bib11">11,12</a>The present study investigated the previously described risk factors. Body mass index (BMI), profession, time spent seated per day, stiffness of body hair, number of baths per week and family history were explored in a large-scale prospective case control trial. The purpose of the current study was to determine the clinical value and quantitative effect of significant risk factors on the pathogenesis of SPD. The results will help to form evidence-based advice for the prevention of the disease. The findings may be useful in correlating the proposed etiological theory with clinical practice and may also be a starting point for minimally invasive or non invasive treatment options.MATERIAL AND METHODStudy designA total of 587 patients with SPD and 2,780 healthy control patients were enrolled for the study. All data were collected prospectively during a 3-year time period and the study was designed as a case-control trial.Patient SelectionPatients in active military service who were diagnosed with SPD in five military hospitals during the study period were enrolled in the trial. The two inclusion criteria included being a soldier in active military service and the presence of SPD. Regardless of previous or further treatment of the disease or co-morbid conditions, all patients with SPD who consented to participate in the study were subjected to a physical examination and clinical interview.Selection of control patientsThe control patients were selected from soldiers who presented for their first medical examination when they were joining the army. All soldiers underwent a first medical evaluation as a part of the standard procedure; however, the soldiers in the control group were examined more carefully for the study parameters. Patients with current or previous, symptomatic or asymptomatic SPD and soldiers who did not consent to study participation were excluded from the control group.Data CollectionWith the aim of evaluating previously defined risk factors, a data collection form was designed (<a class="elsevierStyleCrossRef" href="#t1-cln_65p125">Table 1</a>). All physicians who would work in data collection were informed about the description of the data. Surgeons filled in the data collection forms during the first meeting with the patients. For the control group, physicians examined and filled in the data collection form at a recruit’s initial medical exam.<elsevierMultimedia ident="t1-cln_65p125"></elsevierMultimedia>During these examinations, demographic and basic medical data, including patients’ profession, age, sex, weight and height were documented. Moreover, time spent seated per day, body hair rate, number of baths per week and family history of SPD were recorded by the physicians for both patients with SPD and control patients.Patient history and physical examination findings in the patient group were recorded for routine clinical evaluation; such data were used for another descriptive paper that discusses the clinical presentation of disease.Outcome ParameterAge, sex, BMI, profession, time spent seated per day, body hair rate, number of baths per week and family history were compared between the patients with SPD and the control patients. The odds ratio (OR) for every parameter and for the three most predictive risk factors were calculated. The OR for all predictive risk factors were adjusted with a multivariate analysis for age, BMI, time spent seated per day, body hair rate and number of baths per week.Description of dataBMIWeight (kilogram) and height (meter) for each patient and control were measured and BMI was calculated by the standard formula (weight/height<a class="elsevierStyleCrossRef" href="#bib2">2</a>). Case and controls were divided into three groups, which are as follows: normal (BMI<25), overweight (BMI between 25–30) and obese (BMI >30).OccupationThe occupation performed the most during two years prior to the diagnosis of SPD was accepted as the patient’s profession. If the patient had worked, but not in the same occupation for more than six months during this time period, the patient was considered an irregular worker.Time spent seated per dayThe physician asked each patient about the time period that they spent sitting on a seat during their usual work practice. Patients were then grouped into two groups including those who spent more and those who spent less than six hours of sitting time. “Six hours” is accepted as the maximum possible sitting time of a worker who has a job requiring sitting down for prolonged period.Body hair rateBody hair rate was also graded subjectively. The levels used for the study are as follows: “hairless” if the intergluteal sulcus was clean with a minimal amount of hair, “hairy” if the intergluteal sulcus was full of hair and “mild hairy” if there were few hairs.Number of baths in a weekThe bath and shower habits of the patients and controls were determined by interview and the approximate number of baths per week was recorded.Family history about SPDPresence of SPD in one or more family members (i.e., father, mother, brother or sister) was self-reported by the patients and subsequently recorded by interviewers.Statistical AnalysisStatistical analysis was performed with SPSS software version 11.5 (SPSS Inc, Chi., II., USA). Clinical data were expressed as means ± standard deviation, ranges and percentages. We investigated the effects of the variables on SPD by calculating crude (unadjusted) odds ratios in univariate logistic regression analyses. We then conducted multivariate analyses. We reduced the model by using a backward elimination method and eliminated potential risk factors by using likelihood ratio tests. A p-value of <0.05 was accepted as statistically significant.RESULTSDuring the study period, 587 patients and 2,780 controls were evaluated.Age and SexAll patients and controls were white and male. The mean age was 22.49 ± 2.97 in the patient group, as compared with 21.02 ± 1.73 for the control group. The crude OR and the adjusted OR were 1.32 and 1.31, respectively. The 95% confidence interval (CI) was 1.27–1.38 and 1.25–1.37, respectively.BMIMean BMI was slightly higher in patients with SPD. It was 23.8 ± 2.7 (range 16.1–36.8) in the patient group and 22.7 ± 2.5 (range 16.1–36.9) in the control group. (p<0.001). The majority of patients (70.5%) and controls (83.5%) had a BMI under 25 (<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>). Individuals having a BMI less than 25 were used as the reference. Based on the comparison of the normal weight and overweight groups, the crude OR was 2.14 (95% CI: 1.74–2.64) and the adjusted OR was 1.56 (95% CI: 1.20–2.03). The difference was statistically significant in both univariate and multivariate analysis (p<0.001 and p= 0.001, respectively). Only 2% of patients and 1.3% of controls were in the obese group and the difference in OR was not significant in the univariate and multivariate analyses when compared with normal weight individuals. (p=0.08 and p=0.598 respectively) (<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>).<elsevierMultimedia ident="t3-cln_65p125"></elsevierMultimedia><elsevierMultimedia ident="t2-cln_65p125"></elsevierMultimedia>OccupationA total of 56 job titles were described for both groups. The most commonly reported occupations in the patient group were farmers (15%), irregular workers (13.3%), Salespeople (11.9%), unemployed (11.4%) and drivers (5.8%). The most popular jobs in the control group were irregular workers (20.4%), unemployed (12.1%), drivers (6.7%), farmers (6.04%) and technicians (5.4 %). There was no particular occupation associated with SPD.Time Spent Seated Per DayTime spent seated per day was significantly higher in the patient group. A total of 56% of patients sat down on a seat for more than six hours, as compared with 27.8% of controls (p<0.001) (<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>). The crude OR was 3.31 (95% CI= 2.75–3.97) and the adjusted OR was 4.03 (95% CI= 3.22–5.05) for individuals who sat down for more than six hours, as compared with the group who sat down for less than six hours per day (p<0.001) (<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>).Body Hair RateThe percentage of hairy and mildly hairy persons was significantly higher in the patient group than in the control group (39.5% and 52.5%, as compared with 14.0% and 41.8%, respectively) (p<0.001) (<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>). The crude OR was calculated as 6.93 for mildly hairy people (95% CI=5.05–9.52) and 15.54 for hairy people (95% CI=11.13–21.70). The adjusted OR was also highly significant for both groups. The adjusted OR was 5.15 (95% CI: 3.65–7.27) for the mildly hairy group and 9.23 (95% CI: 6.31–13.51) for the hairy group. The p-value was <0.001 for all analyses concerning body hair rate (<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>).Number of Baths in a WeekThe mean number of baths in a week was 2.26 ± 0.57 in the patient group and 3.04 ± 1.17 in the control group (p<0.001). The rate of people who take a bath two times or less per week was 71.4% in the patient group and 31.2% in the control group (<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>). The crude OR for SPD was 5.50-fold (95% CI:4.52–6.70) and adjusted OR was 6.33-fold (95% CI:5.02–7.99) higher in people who take two or less showers or baths per week compared with those who take three or more baths per week (p<0.001) (<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>).Family History of SPDFamily history of SPD was slightly higher in the patient group, but it was not statistically significant. Presence of SPD in first degree family members was exposed in the family histories of 98 patients (16.7%) and 405 controls (14.6%) (p=0.189) (<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>).The three most predictive risk factors were body hair rate, bathing habituation and sitting time. A total of 111 people from both the patient and control groups possessed these three risk factors simultaneously and 80 of those individuals were from patient group (72.07%). In contrast, these 3 risk factors were all absent in 602 people, and only 7 of these were from patient group (1.16%). With a logistic regression analysis, the risk is 219-fold higher for hairy people who shower or bath two or less times per week and sit more than six hours per day compared with hairless people who shower or bath three or more times per week and sit less than six hours in a day, where OR is 219.36 and 95% CI is 93.50–514.62 (p<0.001).DISCUSSIONStudies based on large patient series about SPD are usually reported from army hospitals.<a class="elsevierStyleCrossRef" href="#bib12">12</a>–<a class="elsevierStyleCrossRef" href="#bib14">14</a> The patient records analyzed in this study revealed that SPD is the second commonly seen surgical pathology among soldiers. Patient number and homogeneity of groups provide researchers with an opportunity to design prospective, large-scale clinical trials to evaluate risk factors for SPD. While soldiers are usually young active males who are not representative of general population, pilonidal disease affects mainly white males in this age group and study results may be applied to a broad population.From its first description in 1930 to the middle of 20th century, many reaearchers have attempted to explain SPD with a congenital etiology based theory. Patey and Scarff first proposed the hypothesis that the disease results from suction of hair from the surrounding skin.<a class="elsevierStyleCrossRef" href="#bib15">15</a> They maintain that the pilonidal cyst is a chronic disease caused by penetration of short, stiff hairs into the subcutaneous tissues and create of foreign body reaction. Bascom showed that the midline pits are enlarged and distorted hair follicles.<a class="elsevierStyleCrossRef" href="#bib16">16</a> Enlarged hair follicles in the midline are the portals of entry for the hairs and extension occurs by persistent low-grade infection.<a class="elsevierStyleCrossRef" href="#bib8">8</a> Gravity and motion of the gluteal folds have been suggested as a cause of creation of a vacuum that pulls on the follicles.<a class="elsevierStyleCrossRef" href="#bib17">17</a> To explain how these hairs make their way into the tissues, Karydakis attributed the cause to three main factors.<a class="elsevierStyleCrossRef" href="#bib14">14</a> Those factors include the invader, which is the loose hair; the force, which causes the insertion; and the vulnerability of the skin to the insertion of hair at the depth of the natal cleft. Previously described risk factors are acting on these causation factors.Hair is the main initiative agent in all theories that attempt to explain the pathogenesis of SPD, which may be the reason for the male predomination of the disease. Hair is the invader agent according to Karydakis theory.<a class="elsevierStyleCrossRef" href="#bib14">14</a> Clinical observations also revealed that patients with SPD are usually hairy men. The present study evaluated body hair rate as a risk factor. Increasing body hair rate was matched to 9.23-fold higher risk of SPD even after adjustment for other risk factors. The graduation of hair rate was made by physicians according to a three-graded subjective scale. Using this scale, it is relatively easy to distinguish hairy and hairless people. A mild hairy group is defined for possible confusions. Risk for SPD was significantly higher for the hairy and mild hairy groups. An objective measurement technique may be used for definition of body hair rate. This technique will help to obtain objective results, however, it must be simple to use in a large patient group.While there is no previous study evaluating the relation between the bathing habituation and SPD, we hypothesized that this relation affected the amount of loose hair at the intergluteal groove. The adjusted risk of SPD diagnosis is 6.33-fold greater for those who bath two or less times per week than the risk for those people who take three or more baths per week. The results revealed that the cleaning of intergluteal sulcus may prevent this disease. The definition of bathing number is relatively subjective and determined by patient self-reporting. A prospective randomized trial aimed to detect effect of bathing habituation is not easy. A very large sample size and long follow-up time are needed to conduct such a study.SPD is rare with black and Asian people.<a class="elsevierStyleCrossRefs" href="#bib8">8,9</a> Turkish people are mostly white and the number of black people is negligible. All of the individuals in the patient and control groups were white males in this study.SPD was referred to as the “jeep disease” during Second World War.<a class="elsevierStyleCrossRef" href="#bib3">3</a> Drivers are known as an at risk group for this condition. Further articles mentioned to the relationship of occupation and SPD. Several case reports have described a similar condition arising in the clefts between the fingers of barbers or hairdressers.<a class="elsevierStyleCrossRef" href="#bib18">18</a> We recorded and analyzed occupation in both the patient and control groups, but could not determine any profession indicating SPD. Some limitations have made a systematic analysis difficult to achieve; for example, it is difficult to classify occupations into meaningful groups. Although we tried to evaluate occupations, a total of 56 job titles were used and most of the individuals in the patient and control groups did not have a regular job. It is possible to say that there were more drivers in the control group compared with patient group. Current cars and trucks are comfortable and roads are flat. It is possible that improved vehicle and road conditions are the reason today’s drivers experience SPD less often than with their colleagues who rode in a jumping jeep on bumpy field roads during the Second World War. It is not easy to deny the relation between occupation and SPD according to study results; although occupation seems to be indirectly related to sitting time and body cleaning.Sitting time in a day on a seat was another risk factor evaluated in the study. The adjusted risk of SPD was 4.3-fold higher for individuals who were sitting more than six hours in a day. The majority of the classical articles about SPD indicate a relation between the long sitting time and this disease; however, we could not find a clinical trial in the literature that was showing this relation.The role of obesity as a causative factor and its effect on the effectiveness of some treatment modalities has been discussed in the literature. In a clinical trial containing 419 patients and 213 controls, BMI was reported to be slightly higher in the patient group, but the difference was not statistically significant.<a class="elsevierStyleCrossRef" href="#bib10">10</a> In another study, the authors declared that the Karydakis procedure for managing chronic pilonidal sinus in obese patients was easy to perform, had a fast healing time, required a short hospital stay, enabled a rapid return to work and resulted in a low recurrence rate.<a class="elsevierStyleCrossRef" href="#bib19">19</a> In contrast, Cubukcu et all. stated that obese patients with high BMI have a higher risk of recurrence of pilonidal sinus disease after surgical intervention.<a class="elsevierStyleCrossRef" href="#bib11">11</a> A recent paper that included 125 patients and 125 controls revealed that sacrococcygeal subcutaneous fatty tissue is thicker in the patient group.<a class="elsevierStyleCrossRef" href="#bib20">20</a> In the present study, the independent risk was calculated as 1.56 and 1.26 for overweight and obese people, respectively, compared with people who had a BMI under 25. Most of the patients and all of the controls in this study were soldiers in active military service, and all were young people. Because there were only a few obese individuals in both groups, this group could not be analyzed; however, the overweight group was appropriate for analysis. The effect of BMI may be better evaluated in a community-based population. Our results revealed that obesity is a relatively less important risk factor for SPD. The intergluteal groove is a deep moist area in which broken hairs and foreign bodies can collect, leading to infection or invasion of the skin. The deepness of the intergluteal sulcus may be different in people based on BMI or personal body characteristics. We thought that the depth of the intergluteal sulcus can affect the amount of loose hair collected in it.The prevalence of a family history of SPD was around 15% in both groups, a difference that was not statistically significant. These findings suggest that this condition does not occur on a congenital basis.The mean age was 22.49 ± 2.97 in the patient group, as compared with 21.02 ± 1.73 for the control group. Although the finding was not clinically significant due to the large sample size, the result was statistically significant (p <0.001).CONCLUSIONHirsute people who sit for longer periods of time and have a decreased number of baths per week have a 219-fold increased risk for SPD. This finding is extremely significant and important because simple precautions may be proposed for prevention. Careful cleaning of the intergluteal sulcus should be conducted, especially among people who are hirsute. Hairy people should take more baths and use skin care products that reduce unwanted hairs. Bathing facilities and opportunities to bath must be arranged for people who live communally, such as soldiers. People who have occupations requiring sitting down in a seat for long hours must choose more comfortable seats and must try to stand up on every occasion." "textoCompletoSecciones" => array:1 [ "secciones" => array:7 [ 0 => array:2 [ "identificador" => "xpalclavsec1582521" "titulo" => "KEYWORDS:" ] 1 => array:2 [ "identificador" => "cesec10" "titulo" => "INTRODUCTION" ] 2 => array:3 [ "identificador" => "cesec20" "titulo" => "MATERIAL AND METHOD" "secciones" => array:7 [ 0 => array:2 [ "identificador" => "cesec30" "titulo" => "Study design" ] 1 => array:2 [ "identificador" => "cesec40" "titulo" => "Patient Selection" ] 2 => array:2 [ "identificador" => "cesec50" "titulo" => "Selection of control patients" ] 3 => array:2 [ "identificador" => "cesec60" "titulo" => "Data Collection" ] 4 => array:2 [ "identificador" => "cesec70" "titulo" => "Outcome Parameter" ] 5 => array:3 [ "identificador" => "cesec80" "titulo" => "Description of data" "secciones" => array:6 [ 0 => array:2 [ "identificador" => "cesec90" "titulo" => "BMI" ] 1 => array:2 [ "identificador" => "cesec100" "titulo" => "Occupation" ] 2 => array:2 [ "identificador" => "cesec110" "titulo" => "Time spent seated per day" ] 3 => array:2 [ "identificador" => "cesec120" "titulo" => "Body hair rate" ] 4 => array:2 [ "identificador" => "cesec130" "titulo" => "Number of baths in a week" ] 5 => array:2 [ "identificador" => "cesec140" "titulo" => "Family history about SPD" ] ] ] 6 => array:2 [ "identificador" => "cesec150" "titulo" => "Statistical Analysis" ] ] ] 3 => array:3 [ "identificador" => "cesec160" "titulo" => "RESULTS" "secciones" => array:7 [ 0 => array:2 [ "identificador" => "cesec170" "titulo" => "Age and Sex" ] 1 => array:2 [ "identificador" => "cesec180" "titulo" => "BMI" ] 2 => array:2 [ "identificador" => "cesec190" "titulo" => "Occupation" ] 3 => array:2 [ "identificador" => "cesec200" "titulo" => "Time Spent Seated Per Day" ] 4 => array:2 [ "identificador" => "cesec210" "titulo" => "Body Hair Rate" ] 5 => array:2 [ "identificador" => "cesec220" "titulo" => "Number of Baths in a Week" ] 6 => array:2 [ "identificador" => "cesec230" "titulo" => "Family History of SPD" ] ] ] 4 => array:2 [ "identificador" => "cesec240" "titulo" => "DISCUSSION" ] 5 => array:2 [ "identificador" => "cesec250" "titulo" => "CONCLUSION" ] 6 => array:1 [ "titulo" => "REFERENCES" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-08-17" "fechaAceptado" => "2009-10-26" "PalabrasClave" => array:1 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "KEYWORDS:" "identificador" => "xpalclavsec1582521" "palabras" => array:8 [ 0 => "Pilonidal disease" 1 => "Pilonidal sinus" 2 => "Sacrococcygeal" 3 => "Risk factors" 4 => "Etiology" 5 => "Stiffness of body hair" 6 => "Body Mass Index" 7 => "BMI" ] ] ] ] "tieneResumen" => true "resumen" => array:1 [ "en" => array:2 [ "resumen" => "PURPOSESacrococcygeal pilonidal disease is a source of one of the most common surgical problems among young adults. While male gender, obesity, occupations requiring sitting, deep natal clefts, excessive body hair, poor body hygiene and excessive sweating are described as the main risk factors for this disease, most of these need to be verified with a clinical trial. The present study aimed to evaluate the value and effect of these factors on pilonidal disease. METHODPreviously proposed main risk factors were evaluated in a prospective case control study that included 587 patients with pilonidal disease and 2,780 healthy control patients. RESULTSStiffness of body hair, number of baths and time spent seated per day were the three most predictive risk factors. Adjusted odds ratios were 9.23, 6.33 and 4.03, respectively (p<0.001). With an adjusted odds ratio of 1.3 (p<.001), body mass index was another risk factor. Family history was not statistically different between the groups and there was no specific occupation associated with the disease. CONCLUSIONSHairy people who sit down for more than six hours a day and those who take a bath two or less times per week are at a 219-fold increased risk for sacrococcygeal pilonidal disease than those without these risk factors. For people with a great deal of hair, there is a greater need for them to clean their intergluteal sulcus. People who engage in work that requires sitting in a seat for long periods of time should choose more comfortable seats and should also try to stand whenever possible." "secciones" => array:4 [ 0 => array:2 [ "identificador" => "ceabs10" "titulo" => "PURPOSE" ] 1 => array:2 [ "identificador" => "ceabs20" "titulo" => "METHOD" ] 2 => array:2 [ "identificador" => "ceabs30" "titulo" => "RESULTS" ] 3 => array:2 [ "identificador" => "ceabs40" "titulo" => "CONCLUSIONS" ] ] ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "t1-cln_65p125" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "tablatextoimagen" => array:1 [ 0 => array:1 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Name: \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Patient ( ), Control ( ) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Date and hospital name: \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Age and sex: \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Length (cm): \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Weight (kg): \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Profession<a class="elsevierStyleCrossRef" href="#tfn1-cln_65p125">(*)</a> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Time spent seated per day: <6 hour ( ), ≥6 hour ( ) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Body hair rate: hairless ( ), mildly hairy ( ), hairy ( ) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Number of baths in a week: \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Family history<a class="elsevierStyleCrossRef" href="#tfn2-cln_65p125">(**)</a> Positive ( ), Negative ( ) \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] ] ] "notaPie" => array:2 [ 0 => array:3 [ "identificador" => "tfn1-cln_65p125" "etiqueta" => "(*)" "nota" => "The job mostly done during the two years prior to the sacrococcygeal pilonidal disease (SPD). If the patient had worked, but not in the same job for more than six months during this time period, they were considered to be an irregular worker." ] 1 => array:3 [ "identificador" => "tfn2-cln_65p125" "etiqueta" => "(**)" "nota" => "Presence of SPD in father, mother, brother or sister." ] ] ] "descripcion" => array:1 [ "en" => "Data collection form" ] ] 1 => array:7 [ "identificador" => "t2-cln_65p125" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "tablatextoimagen" => array:1 [ 0 => array:1 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Unadjusted OR \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">95% CI \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">P-value \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Adjusted<a class="elsevierStyleCrossRef" href="#tfn3-cln_65p125">(a)</a> OR \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">95% CI \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">P-value \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="7" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Body Mass Index</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><25 (Reference) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">25–30 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2.14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.74–2.64 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.56 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.20– 2.03 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">>30 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.82 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.94–3.52 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.08 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.26 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.54– 2.94 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.60 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="7" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Time Spent Seated Per Day</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><6 hour (Reference) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">≥6 hour \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3.31 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2.75–3.97 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4.03 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3.22– 5.05 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="7" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Body Hair Rate</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hairless (Reference) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Mild \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">6.93 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5.05–9.52 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5.15 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3.65–7.27 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hairy \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">15.54 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">11.13–1.70 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">9.23 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">6.31–13.51 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="7" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Number of Baths in a Week</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 or more (Reference) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">2 or less \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">5.50 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">4.52–6.70 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">6.33 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">5.02– 7.99 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] ] ] "notaPie" => array:1 [ 0 => array:3 [ "identificador" => "tfn3-cln_65p125" "etiqueta" => "(a)" "nota" => "Adjusted for body mass index, time spent seated per day, body hair rate and number of baths in a week. OR: Odds ratio, CI: Confidence interva" ] ] ] "descripcion" => array:1 [ "en" => "Effects of various variables on pilonodial disease based on univariate statistics and multivariate logistic regression analysis" ] ] 2 => array:7 [ "identificador" => "t3-cln_65p125" "etiqueta" => "Table 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:1 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " colspan="2" align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Patient</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " colspan="2" align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Control</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " colspan="2" align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Total</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">P-value \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">n \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">% \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">n \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">% \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">n \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">% \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="8" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Body Mass Index</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><25 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">414 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">70,5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2321 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">83.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2735 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">81.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">25–30 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">161 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">27.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">422 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">15.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">583 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">17.3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">>30 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">37 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">49 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.60 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="8" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Time sitting on a seat per day</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><6 hour \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">258 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">44.0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2006 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">72.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2264 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">67.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">≥6 hour \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">329 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">56.0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">774 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">27.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1103 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">32.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="8" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Stiffness of Body Hair</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hairless \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">47 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8.0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1228 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">44.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1275 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">37.9 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Mild \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">308 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">52.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1161 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">41.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1469 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">43.06 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hairy \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">232 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">39.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">390 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">14.0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">622 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">18.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="8" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Number of Baths in a Week</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 or more \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">168 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">28.62 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1913 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">68.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2081 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">61.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 or less \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">419 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">71.38 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">867 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">31.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1286 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">38.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " colspan="8" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Family History for Sacrococcygeal Pilonidal Disease (SPD)</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Positive \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">98 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">16.7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">405 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">14.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">503 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t">14.9 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Negative \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">489 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">83.3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">2375 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">85.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">2864 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">85.1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="center" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] ] ] ] "descripcion" => array:1 [ "en" => "Distribution of risk factors in the patient and control groups" ] ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "cebibsec10" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sacrococcygeal pilonidal sinus: historical review, pathological insight and surgical options" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => """ S Chintapatla \n \t\t\t\t\t\t\t\t """ 1 => """ N Safarani \n \t\t\t\t\t\t\t\t """ 2 => """ S Kumar \n \t\t\t\t\t\t\t\t """ 3 => """ N Haboubi \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => 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""" H Dettmann \n \t\t\t\t\t\t\t\t """ 3 => """ AL Boulesteix \n \t\t\t\t\t\t\t\t """ 4 => """ W Duesel \n \t\t\t\t\t\t\t\t """ 5 => """ S Petersen \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00384-007-0389-5" "Revista" => array:6 [ "tituloSerie" => "Int J Colorectal Dis" "fecha" => "2008" "volumen" => "23" "paginaInicial" => "359" "paginaFinal" => "364" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18043929" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New approach to the problem of pilonidal sinus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => """ GE Karydakis \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/s0140-6736(88)90597-1" "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" 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"contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pilonidal sinus: origin from follicles of hairs and results of follicle removal as treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => """ J Bascom \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surgery" "fecha" => "1980" "volumen" => "87" "paginaInicial" => "567" "paginaFinal" => "572" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7368107" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pilonidal sinus. A new theory of origin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => """ R Brearley \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Surg" "fecha" => "1955" "volumen" => "43" "paginaInicial" => "455" "paginaFinal" => "462" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Barber’s hair sinus in a female hairdresser: uncommon manifestation of an occupational disease: a case report" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => """ C Efthimiadis \n \t\t\t\t\t\t\t\t """ 1 => """ C Kosmidis \n \t\t\t\t\t\t\t\t """ 2 => """ G Anthimidis \n \t\t\t\t\t\t\t\t """ 3 => """ M Grigoriou \n \t\t\t\t\t\t\t\t """ 4 => """ S Levva \n \t\t\t\t\t\t\t\t """ 5 => """ P Fachantidis \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/1757-1626-1-214" "Revista" => array:5 [ "tituloSerie" => "Cases J" "fecha" => "2008" "volumen" => "1" "paginaInicial" => "214" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18837967" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of obesity on the results of Karydakis technique for the management of chronic pilonidal sinus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => """ M Sakr \n \t\t\t\t\t\t\t\t """ 1 => """ H El-Hammadi \n \t\t\t\t\t\t\t\t """ 2 => """ M Moussa \n \t\t\t\t\t\t\t\t """ 3 => """ S Arafa \n \t\t\t\t\t\t\t\t """ 4 => """ M Rasheed \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00384-002-0407-6" "Revista" => array:6 [ "tituloSerie" => "Int J Colorectal Dis" "fecha" => "2003" "volumen" => "18" "paginaInicial" => "36" "paginaFinal" => "39" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12458379" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The importance of local subcutaneous fat thickness in pilonidal disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => """ O Balik \n \t\t\t\t\t\t\t\t """ 1 => """ AA Balik \n \t\t\t\t\t\t\t\t """ 2 => """ KY Polat \n \t\t\t\t\t\t\t\t """ 3 => """ B Aydinli \n \t\t\t\t\t\t\t\t """ 4 => """ M Kantarci \n \t\t\t\t\t\t\t\t """ 5 => """ C Aliagaoglu \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s10350-006-0672-5" "Revista" => array:6 [ "tituloSerie" => "Dis Colon Rectum" "fecha" => "2006" "volumen" => "49" "paginaInicial" => "1755" "paginaFinal" => "1757" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17036206" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/18075932/0000006500000002/v1_202212011522/S180759322202484X/v1_202212011522/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/18075932/0000006500000002/v1_202212011522/S180759322202484X/v1_202212011522/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S180759322202484X?idApp=UINPBA00004N"]

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Clinical Sciences

Ali HarlakI, Oner MentesI, Selim KilicII, Kagan CoskunI, Kazim DumanIII, Fahri YilmazIV

I Departmen of General Surgery, Gulhane Military Medical Academy - Ankara, Turkey

II Department of Public Health, Gulhane Military Medical Academy - Ankara, Turkey

III Department of General Surgery, Gumussuyu Military Hospital - Istanbul, Turkey

IV Department of General Surgery, Golcuk Military Hospital - Golcuk, Turkey Tel.: 90 3123045015

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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="cesec10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle60">INTRODUCTION</span><p id="para10" class="elsevierStylePara elsevierViewall">Sacrococcygeal pilonidal disease &#40;SPD&#41; is a well recognized source of a common surgical problem affecting primarily white men between puberty and their early thirties&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> The name of the disease originated from Latin&#44; meaning nest of hair&#46; The disease frequently occurs as a chronic infection of the skin in the region of the buttock crease&#46; SPD was first described by Hodges in 1880 and later&#44; in 1833&#44; was described by Herbert Mayo as a hair-containing sinus&#46;<a class="elsevierStyleCrossRef" href="#bib2">2</a> Mayo&#8217;s findings were of a characteristic epithelial track &#40;the sinus&#41; that generally contains hair and is located in the skin of the natal cleft&#46; The condition was commonly diagnosed in jeep drivers during the Second World War&#44; which led to it being known as &#8220;jeep disease&#46;&#8221;<a class="elsevierStyleCrossRef" href="#bib3">3</a> Although not as common&#44; pilonidal disease may occur in other body parts&#44; such as the clefts between the fingers of barbers or hairdressers&#46;<a class="elsevierStyleCrossRef" href="#bib4">4</a></p><p id="para20" class="elsevierStylePara elsevierViewall">For a long time&#44; the cause of SPD has been a matter of debate&#46; Until the second half of the 20<span class="elsevierStyleSup">th</span> century&#44; SPD was thought to be secondary to a congenital remnant of an epithelial-lined tract of postcoccygeal epidermal cell rests or vestigial scent cells&#46; A variety of explanations have supported the congenital theory&#46; Some authors have suggested that the persistence of a caudal remnant of the neural canal forms small cysts&#44; which cause SPD&#46;<a class="elsevierStyleCrossRef" href="#bib5">5</a> Another hypothesis for SPD provides that SPD is the result of a formation of dermal inclusions by the cystic changes of sequestered epithelial rests&#46;<a class="elsevierStyleCrossRef" href="#bib6">6</a> Excessive involution of the human tail has been accused of attracting skin into a subcutaneous area and results in an epithelium-lined tract&#46;<a class="elsevierStyleCrossRef" href="#bib7">7</a> SPD is now&#44; however&#44; widely accepted as an acquired disorder&#46; SPD is more common in men and in hirsute people&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> It usually occurs after puberty&#44; and a linkage between the disease and various occupations has been demonstrated&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> In addition&#44; there is a high recurrence rate of SPD after surgical excision&#46; These factors argue against the validity of the congenital theory to explain SPD&#46; Further&#44; congenital tracts do not contain hair and are lined by cuboidal epithelium&#46;<a class="elsevierStyleCrossRef" href="#bib8">8</a></p><p id="para30" class="elsevierStylePara elsevierViewall">Male gender&#44; obesity&#44; occupations or sports requiring sitting&#44; a deep natal cleft&#44; excessive body hair&#44; stiff or coarse hair&#44; poor body hygiene and excessive sweating are described as the primary risk factors for SPD&#46;<a class="elsevierStyleCrossRef" href="#bib9">9</a> However&#44; there is a noted lack of prospective studies in the literature that analyze and confirm these risk factors&#46; There are only a few studies evaluating risk factors for SPD&#44; and they are generally focused on the role of obesity&#46;<a class="elsevierStyleCrossRefs" href="#bib11">11&#44;12</a></p><p id="para40" class="elsevierStylePara elsevierViewall">The present study investigated the previously described risk factors&#46; Body mass index &#40;BMI&#41;&#44; profession&#44; time spent seated per day&#44; stiffness of body hair&#44; number of baths per week and family history were explored in a large-scale prospective case control trial&#46; The purpose of the current study was to determine the clinical value and quantitative effect of significant risk factors on the pathogenesis of SPD&#46; The results will help to form evidence-based advice for the prevention of the disease&#46; The findings may be useful in correlating the proposed etiological theory with clinical practice and may also be a starting point for minimally invasive or non invasive treatment options&#46;</p></span><span id="cesec20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle70">MATERIAL AND METHOD</span><span id="cesec30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle80">Study design</span><p id="para50" class="elsevierStylePara elsevierViewall">A total of 587 patients with SPD and 2&#44;780 healthy control patients were enrolled for the study&#46; All data were collected prospectively during a 3-year time period and the study was designed as a case-control trial&#46;</p></span><span id="cesec40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle90">Patient Selection</span><p id="para60" class="elsevierStylePara elsevierViewall">Patients in active military service who were diagnosed with SPD in five military hospitals during the study period were enrolled in the trial&#46; The two inclusion criteria included being a soldier in active military service and the presence of SPD&#46; Regardless of previous or further treatment of the disease or co-morbid conditions&#44; all patients with SPD who consented to participate in the study were subjected to a physical examination and clinical interview&#46;</p></span><span id="cesec50" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle100">Selection of control patients</span><p id="para70" class="elsevierStylePara elsevierViewall">The control patients were selected from soldiers who presented for their first medical examination when they were joining the army&#46; All soldiers underwent a first medical evaluation as a part of the standard procedure&#59; however&#44; the soldiers in the control group were examined more carefully for the study parameters&#46; Patients with current or previous&#44; symptomatic or asymptomatic SPD and soldiers who did not consent to study participation were excluded from the control group&#46;</p></span><span id="cesec60" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle110">Data Collection</span><p id="para80" class="elsevierStylePara elsevierViewall">With the aim of evaluating previously defined risk factors&#44; a data collection form was designed &#40;<a class="elsevierStyleCrossRef" href="#t1-cln_65p125">Table 1</a>&#41;&#46; All physicians who would work in data collection were informed about the description of the data&#46; Surgeons filled in the data collection forms during the first meeting with the patients&#46; For the control group&#44; physicians examined and filled in the data collection form at a recruit&#8217;s initial medical exam&#46;</p><elsevierMultimedia ident="t1-cln_65p125"></elsevierMultimedia><p id="para90" class="elsevierStylePara elsevierViewall">During these examinations&#44; demographic and basic medical data&#44; including patients&#8217; profession&#44; age&#44; sex&#44; weight and height were documented&#46; Moreover&#44; time spent seated per day&#44; body hair rate&#44; number of baths per week and family history of SPD were recorded by the physicians for both patients with SPD and control patients&#46;</p><p id="para100" class="elsevierStylePara elsevierViewall">Patient history and physical examination findings in the patient group were recorded for routine clinical evaluation&#59; such data were used for another descriptive paper that discusses the clinical presentation of disease&#46;</p></span><span id="cesec70" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle120">Outcome Parameter</span><p id="para110" class="elsevierStylePara elsevierViewall">Age&#44; sex&#44; BMI&#44; profession&#44; time spent seated per day&#44; body hair rate&#44; number of baths per week and family history were compared between the patients with SPD and the control patients&#46; The odds ratio &#40;OR&#41; for every parameter and for the three most predictive risk factors were calculated&#46; The OR for all predictive risk factors were adjusted with a multivariate analysis for age&#44; BMI&#44; time spent seated per day&#44; body hair rate and number of baths per week&#46;</p></span><span id="cesec80" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle130">Description of data</span><span id="cesec90" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle140">BMI</span><p id="para120" class="elsevierStylePara elsevierViewall">Weight &#40;kilogram&#41; and height &#40;meter&#41; for each patient and control were measured and BMI was calculated by the standard formula &#40;weight&#47;height<a class="elsevierStyleCrossRef" href="#bib2">2</a>&#41;&#46; Case and controls were divided into three groups&#44; which are as follows&#58; normal &#40;BMI&#60;25&#41;&#44; overweight &#40;BMI between 25&#8211;30&#41; and obese &#40;BMI &#62;30&#41;&#46;</p></span><span id="cesec100" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle150">Occupation</span><p id="para130" class="elsevierStylePara elsevierViewall">The occupation performed the most during two years prior to the diagnosis of SPD was accepted as the patient&#8217;s profession&#46; If the patient had worked&#44; but not in the same occupation for more than six months during this time period&#44; the patient was considered an irregular worker&#46;</p></span><span id="cesec110" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle160">Time spent seated per day</span><p id="para140" class="elsevierStylePara elsevierViewall">The physician asked each patient about the time period that they spent sitting on a seat during their usual work practice&#46; Patients were then grouped into two groups including those who spent more and those who spent less than six hours of sitting time&#46; &#8220;Six hours&#8221; is accepted as the maximum possible sitting time of a worker who has a job requiring sitting down for prolonged period&#46;</p></span><span id="cesec120" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle170">Body hair rate</span><p id="para150" class="elsevierStylePara elsevierViewall">Body hair rate was also graded subjectively&#46; The levels used for the study are as follows&#58; &#8220;hairless&#8221; if the intergluteal sulcus was clean with a minimal amount of hair&#44; &#8220;hairy&#8221; if the intergluteal sulcus was full of hair and &#8220;mild hairy&#8221; if there were few hairs&#46;</p></span><span id="cesec130" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle180">Number of baths in a week</span><p id="para160" class="elsevierStylePara elsevierViewall">The bath and shower habits of the patients and controls were determined by interview and the approximate number of baths per week was recorded&#46;</p></span><span id="cesec140" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle190">Family history about SPD</span><p id="para170" class="elsevierStylePara elsevierViewall">Presence of SPD in one or more family members &#40;i&#46;e&#46;&#44; father&#44; mother&#44; brother or sister&#41; was self-reported by the patients and subsequently recorded by interviewers&#46;</p></span></span><span id="cesec150" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle200">Statistical Analysis</span><p id="para180" class="elsevierStylePara elsevierViewall">Statistical analysis was performed with SPSS software version 11&#46;5 &#40;SPSS Inc&#44; Chi&#46;&#44; II&#46;&#44; USA&#41;&#46; Clinical data were expressed as means &#177; standard deviation&#44; ranges and percentages&#46; We investigated the effects of the variables on SPD by calculating crude &#40;unadjusted&#41; odds ratios in univariate logistic regression analyses&#46; We then conducted multivariate analyses&#46; We reduced the model by using a backward elimination method and eliminated potential risk factors by using likelihood ratio tests&#46; A p-value of &#60;0&#46;05 was accepted as statistically significant&#46;</p></span></span><span id="cesec160" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle210">RESULTS</span><p id="para190" class="elsevierStylePara elsevierViewall">During the study period&#44; 587 patients and 2&#44;780 controls were evaluated&#46;</p><span id="cesec170" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle220">Age and Sex</span><p id="para200" class="elsevierStylePara elsevierViewall">All patients and controls were white and male&#46; The mean age was 22&#46;49 &#177; 2&#46;97 in the patient group&#44; as compared with 21&#46;02 &#177; 1&#46;73 for the control group&#46; The crude OR and the adjusted OR were 1&#46;32 and 1&#46;31&#44; respectively&#46; The 95&#37; confidence interval &#40;CI&#41; was 1&#46;27&#8211;1&#46;38 and 1&#46;25&#8211;1&#46;37&#44; respectively&#46;</p></span><span id="cesec180" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle230">BMI</span><p id="para210" class="elsevierStylePara elsevierViewall">Mean BMI was slightly higher in patients with SPD&#46; It was 23&#46;8 &#177; 2&#46;7 &#40;range 16&#46;1&#8211;36&#46;8&#41; in the patient group and 22&#46;7 &#177; 2&#46;5 &#40;range 16&#46;1&#8211;36&#46;9&#41; in the control group&#46; &#40;p&#60;0&#46;001&#41;&#46; The majority of patients &#40;70&#46;5&#37;&#41; and controls &#40;83&#46;5&#37;&#41; had a BMI under 25 &#40;<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>&#41;&#46; Individuals having a BMI less than 25 were used as the reference&#46; Based on the comparison of the normal weight and overweight groups&#44; the crude OR was 2&#46;14 &#40;95&#37; CI&#58; 1&#46;74&#8211;2&#46;64&#41; and the adjusted OR was 1&#46;56 &#40;95&#37; CI&#58; 1&#46;20&#8211;2&#46;03&#41;&#46; The difference was statistically significant in both univariate and multivariate analysis &#40;p&#60;0&#46;001 and p&#61; 0&#46;001&#44; respectively&#41;&#46; Only 2&#37; of patients and 1&#46;3&#37; of controls were in the obese group and the difference in OR was not significant in the univariate and multivariate analyses when compared with normal weight individuals&#46; &#40;p&#61;0&#46;08 and p&#61;0&#46;598 respectively&#41; &#40;<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="t3-cln_65p125"></elsevierMultimedia><elsevierMultimedia ident="t2-cln_65p125"></elsevierMultimedia></span><span id="cesec190" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle240">Occupation</span><p id="para220" class="elsevierStylePara elsevierViewall">A total of 56 job titles were described for both groups&#46; The most commonly reported occupations in the patient group were farmers &#40;15&#37;&#41;&#44; irregular workers &#40;13&#46;3&#37;&#41;&#44; Salespeople &#40;11&#46;9&#37;&#41;&#44; unemployed &#40;11&#46;4&#37;&#41; and drivers &#40;5&#46;8&#37;&#41;&#46; The most popular jobs in the control group were irregular workers &#40;20&#46;4&#37;&#41;&#44; unemployed &#40;12&#46;1&#37;&#41;&#44; drivers &#40;6&#46;7&#37;&#41;&#44; farmers &#40;6&#46;04&#37;&#41; and technicians &#40;5&#46;4 &#37;&#41;&#46; There was no particular occupation associated with SPD&#46;</p></span><span id="cesec200" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle250">Time Spent Seated Per Day</span><p id="para230" class="elsevierStylePara elsevierViewall">Time spent seated per day was significantly higher in the patient group&#46; A total of 56&#37; of patients sat down on a seat for more than six hours&#44; as compared with 27&#46;8&#37; of controls &#40;p&#60;0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>&#41;&#46; The crude OR was 3&#46;31 &#40;95&#37; CI&#61; 2&#46;75&#8211;3&#46;97&#41; and the adjusted OR was 4&#46;03 &#40;95&#37; CI&#61; 3&#46;22&#8211;5&#46;05&#41; for individuals who sat down for more than six hours&#44; as compared with the group who sat down for less than six hours per day &#40;p&#60;0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>&#41;&#46;</p></span><span id="cesec210" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle260">Body Hair Rate</span><p id="para240" class="elsevierStylePara elsevierViewall">The percentage of hairy and mildly hairy persons was significantly higher in the patient group than in the control group &#40;39&#46;5&#37; and 52&#46;5&#37;&#44; as compared with 14&#46;0&#37; and 41&#46;8&#37;&#44; respectively&#41; &#40;p&#60;0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>&#41;&#46; The crude OR was calculated as 6&#46;93 for mildly hairy people &#40;95&#37; CI&#61;5&#46;05&#8211;9&#46;52&#41; and 15&#46;54 for hairy people &#40;95&#37; CI&#61;11&#46;13&#8211;21&#46;70&#41;&#46; The adjusted OR was also highly significant for both groups&#46; The adjusted OR was 5&#46;15 &#40;95&#37; CI&#58; 3&#46;65&#8211;7&#46;27&#41; for the mildly hairy group and 9&#46;23 &#40;95&#37; CI&#58; 6&#46;31&#8211;13&#46;51&#41; for the hairy group&#46; The p-value was &#60;0&#46;001 for all analyses concerning body hair rate &#40;<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>&#41;&#46;</p></span><span id="cesec220" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle270">Number of Baths in a Week</span><p id="para250" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">The m</span>ean number of baths in a week was 2&#46;26 &#177; 0&#46;57 in the patient group and 3&#46;04 &#177; 1&#46;17 in the control group &#40;p&#60;0&#46;001&#41;&#46; The rate of people who take a bath two times or less per week was 71&#46;4&#37; in the patient group and 31&#46;2&#37; in the control group &#40;<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>&#41;&#46; The crude OR for SPD was 5&#46;50-fold &#40;95&#37; CI&#58;4&#46;52&#8211;6&#46;70&#41; and adjusted OR was 6&#46;33-fold &#40;95&#37; CI&#58;5&#46;02&#8211;7&#46;99&#41; higher in people who take two or less showers or baths per week compared with those who take three or more baths per week &#40;p&#60;0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#t2-cln_65p125">Table 2</a>&#41;&#46;</p></span><span id="cesec230" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle280">Family History of SPD</span><p id="para260" class="elsevierStylePara elsevierViewall">Family history of SPD was slightly higher in the patient group&#44; but it was not statistically significant&#46; Presence of SPD in first degree family members was exposed in the family histories of 98 patients &#40;16&#46;7&#37;&#41; and 405 controls &#40;14&#46;6&#37;&#41; &#40;p&#61;0&#46;189&#41; &#40;<a class="elsevierStyleCrossRef" href="#t3-cln_65p125">Table 3</a>&#41;&#46;</p><p id="para270" class="elsevierStylePara elsevierViewall">The three most predictive risk factors were body hair rate&#44; bathing habituation and sitting time&#46; A total of 111 people from both the patient and control groups possessed these three risk factors simultaneously and 80 of those individuals were from patient group &#40;72&#46;07&#37;&#41;&#46; In contrast&#44; these 3 risk factors were all absent in 602 people&#44; and only 7 of these were from patient group &#40;1&#46;16&#37;&#41;&#46; With a logistic regression analysis&#44; the risk is 219-fold higher for hairy people who shower or bath two or less times per week and sit more than six hours per day compared with hairless people who shower or bath three or more times per week and sit less than six hours in a day&#44; where OR is 219&#46;36 and 95&#37; CI is 93&#46;50&#8211;514&#46;62 &#40;p&#60;0&#46;001&#41;&#46;</p></span></span><span id="cesec240" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle290">DISCUSSION</span><p id="para280" class="elsevierStylePara elsevierViewall">Studies based on large patient series about SPD are usually reported from army hospitals&#46;<a class="elsevierStyleCrossRef" href="#bib12">12</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib14">14</a> The patient records analyzed in this study revealed that SPD is the second commonly seen surgical pathology among soldiers&#46; Patient number and homogeneity of groups provide researchers with an opportunity to design prospective&#44; large-scale clinical trials to evaluate risk factors for SPD&#46; While soldiers are usually young active males who are not representative of general population&#44; pilonidal disease affects mainly white males in this age group and study results may be applied to a broad population&#46;</p><p id="para290" class="elsevierStylePara elsevierViewall">From its first description in 1930 to the middle of 20<span class="elsevierStyleSup">th</span> century&#44; many reaearchers have attempted to explain SPD with a congenital etiology based theory&#46; Patey and Scarff first proposed the hypothesis that the disease results from suction of hair from the surrounding skin&#46;<a class="elsevierStyleCrossRef" href="#bib15">15</a> They maintain that the pilonidal cyst is a chronic disease caused by penetration of short&#44; stiff hairs into the subcutaneous tissues and create of foreign body reaction&#46; Bascom showed that the midline pits are enlarged and distorted hair follicles&#46;<a class="elsevierStyleCrossRef" href="#bib16">16</a> Enlarged hair follicles in the midline are the portals of entry for the hairs and extension occurs by persistent low-grade infection&#46;<a class="elsevierStyleCrossRef" href="#bib8">8</a> Gravity and motion of the gluteal folds have been suggested as a cause of creation of a vacuum that pulls on the follicles&#46;<a class="elsevierStyleCrossRef" href="#bib17">17</a> To explain how these hairs make their way into the tissues&#44; Karydakis attributed the cause to three main factors&#46;<a class="elsevierStyleCrossRef" href="#bib14">14</a> Those factors include the invader&#44; which is the loose hair&#59; the force&#44; which causes the insertion&#59; and the vulnerability of the skin to the insertion of hair at the depth of the natal cleft&#46; Previously described risk factors are acting on these causation factors&#46;</p><p id="para300" class="elsevierStylePara elsevierViewall">Hair is the main initiative agent in all theories that attempt to explain the pathogenesis of SPD&#44; which may be the reason for the male predomination of the disease&#46; Hair is the invader agent according to Karydakis theory&#46;<a class="elsevierStyleCrossRef" href="#bib14">14</a> Clinical observations also revealed that patients with SPD are usually hairy men&#46; The present study evaluated body hair rate as a risk factor&#46; Increasing body hair rate was matched to 9&#46;23-fold higher risk of SPD even after adjustment for other risk factors&#46; The graduation of hair rate was made by physicians according to a three-graded subjective scale&#46; Using this scale&#44; it is relatively easy to distinguish hairy and hairless people&#46; A mild hairy group is defined for possible confusions&#46; Risk for SPD was significantly higher for the hairy and mild hairy groups&#46; An objective measurement technique may be used for definition of body hair rate&#46; This technique will help to obtain objective results&#44; however&#44; it must be simple to use in a large patient group&#46;</p><p id="para310" class="elsevierStylePara elsevierViewall">While there is no previous study evaluating the relation between the bathing habituation and SPD&#44; we hypothesized that this relation affected the amount of loose hair at the intergluteal groove&#46; The adjusted risk of SPD diagnosis is 6&#46;33-fold greater for those who bath two or less times per week than the risk for those people who take three or more baths per week&#46; The results revealed that the cleaning of intergluteal sulcus may prevent this disease&#46; The definition of bathing number is relatively subjective and determined by patient self-reporting&#46; A prospective randomized trial aimed to detect effect of bathing habituation is not easy&#46; A very large sample size and long follow-up time are needed to conduct such a study&#46;</p><p id="para320" class="elsevierStylePara elsevierViewall">SPD is rare with black and Asian people&#46;<a class="elsevierStyleCrossRefs" href="#bib8">8&#44;9</a> Turkish people are mostly white and the number of black people is negligible&#46; All of the individuals in the patient and control groups were white males in this study&#46;</p><p id="para330" class="elsevierStylePara elsevierViewall">SPD was referred to as the &#8220;jeep disease&#8221; during Second World War&#46;<a class="elsevierStyleCrossRef" href="#bib3">3</a> Drivers are known as an at risk group for this condition&#46; Further articles mentioned to the relationship of occupation and SPD&#46; Several case reports have described a similar condition arising in the clefts between the fingers of barbers or hairdressers&#46;<a class="elsevierStyleCrossRef" href="#bib18">18</a> We recorded and analyzed occupation in both the patient and control groups&#44; but could not determine any profession indicating SPD&#46; Some limitations have made a systematic analysis difficult to achieve&#59; for example&#44; it is difficult to classify occupations into meaningful groups&#46; Although we tried to evaluate occupations&#44; a total of 56 job titles were used and most of the individuals in the patient and control groups did not have a regular job&#46; It is possible to say that there were more drivers in the control group compared with patient group&#46; Current cars and trucks are comfortable and roads are flat&#46; It is possible that improved vehicle and road conditions are the reason today&#8217;s drivers experience SPD less often than with their colleagues who rode in a jumping jeep on bumpy field roads during the Second World War&#46; It is not easy to deny the relation between occupation and SPD according to study results&#59; although occupation seems to be indirectly related to sitting time and body cleaning&#46;</p><p id="para340" class="elsevierStylePara elsevierViewall">Sitting time in a day on a seat was another risk factor evaluated in the study&#46; The adjusted risk of SPD was 4&#46;3-fold higher for individuals who were sitting more than six hours in a day&#46; The majority of the classical articles about SPD indicate a relation between the long sitting time and this disease&#59; however&#44; we could not find a clinical trial in the literature that was showing this relation&#46;</p><p id="para350" class="elsevierStylePara elsevierViewall">The role of obesity as a causative factor and its effect on the effectiveness of some treatment modalities has been discussed in the literature&#46; In a clinical trial containing 419 patients and 213 controls&#44; BMI was reported to be slightly higher in the patient group&#44; but the difference was not statistically significant&#46;<a class="elsevierStyleCrossRef" href="#bib10">10</a> In another study&#44; the authors declared that the Karydakis procedure for managing chronic pilonidal sinus in obese patients was easy to perform&#44; had a fast healing time&#44; required a short hospital stay&#44; enabled a rapid return to work and resulted in a low recurrence rate&#46;<a class="elsevierStyleCrossRef" href="#bib19">19</a> In contrast&#44; Cubukcu et all&#46; stated that obese patients with high BMI have a higher risk of recurrence of pilonidal sinus disease after surgical intervention&#46;<a class="elsevierStyleCrossRef" href="#bib11">11</a> A recent paper that included 125 patients and 125 controls revealed that sacrococcygeal subcutaneous fatty tissue is thicker in the patient group&#46;<a class="elsevierStyleCrossRef" href="#bib20">20</a> In the present study&#44; the independent risk was calculated as 1&#46;56 and 1&#46;26 for overweight and obese people&#44; respectively&#44; compared with people who had a BMI under 25&#46; Most of the patients and all of the controls in this study were soldiers in active military service&#44; and all were young people&#46; Because there were only a few obese individuals in both groups&#44; this group could not be analyzed&#59; however&#44; the overweight group was appropriate for analysis&#46; The effect of BMI may be better evaluated in a community-based population&#46; Our results revealed that obesity is a relatively less important risk factor for SPD&#46; The intergluteal groove is a deep moist area in which broken hairs and foreign bodies can collect&#44; leading to infection or invasion of the skin&#46; The deepness of the intergluteal sulcus may be different in people based on BMI or personal body characteristics&#46; We thought that the depth of the intergluteal sulcus can affect the amount of loose hair collected in it&#46;</p><p id="para360" class="elsevierStylePara elsevierViewall">The prevalence of a family history of SPD was around 15&#37; in both groups&#44; a difference that was not statistically significant&#46; These findings suggest that this condition does not occur on a congenital basis&#46;</p><p id="para370" class="elsevierStylePara elsevierViewall">The mean age was 22&#46;49 &#177; 2&#46;97 in the patient group&#44; as compared with 21&#46;02 &#177; 1&#46;73 for the control group&#46; Although the finding was not clinically significant due to the large sample size&#44; the result was statistically significant &#40;p &#60;0&#46;001&#41;&#46;</p></span><span id="cesec250" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle300">CONCLUSION</span><p id="para380" class="elsevierStylePara elsevierViewall">Hirsute people who sit for longer periods of time and have a decreased number of baths per week have a 219-fold increased risk for SPD&#46; This finding is extremely significant and important because simple precautions may be proposed for prevention&#46; Careful cleaning of the intergluteal sulcus should be conducted&#44; especially among people who are hirsute&#46; Hairy people should take more baths and use skin care products that reduce unwanted hairs&#46; Bathing facilities and opportunities to bath must be arranged for people who live communally&#44; such as soldiers&#46; People who have occupations requiring sitting down in a seat for long hours must choose more comfortable seats and must try to stand up on every occasion&#46;</p></span></span>"
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          "titulo" => "MATERIAL AND METHOD"
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              "titulo" => "Body Hair Rate"
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              "titulo" => "Number of Baths in a Week"
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              "titulo" => "Family History of SPD"
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    "fechaRecibido" => "2009-08-17"
    "fechaAceptado" => "2009-10-26"
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        "resumen" => "<span id="ceabs10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle10">PURPOSE</span><p id="spara40" class="elsevierStyleSimplePara elsevierViewall">Sacrococcygeal pilonidal disease is a source of one of the most common surgical problems among young adults&#46; While male gender&#44; obesity&#44; occupations requiring sitting&#44; deep natal clefts&#44; excessive body hair&#44; poor body hygiene and excessive sweating are described as the main risk factors for this disease&#44; most of these need to be verified with a clinical trial&#46; The present study aimed to evaluate the value and effect of these factors on pilonidal disease&#46;</p></span> <span id="ceabs20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle20">METHOD</span><p id="spara50" class="elsevierStyleSimplePara elsevierViewall">Previously proposed main risk factors were evaluated in a prospective case control study that included 587 patients with pilonidal disease and 2&#44;780 healthy control patients&#46;</p></span> <span id="ceabs30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle30">RESULTS</span><p id="spara60" class="elsevierStyleSimplePara elsevierViewall">Stiffness of body hair&#44; number of baths and time spent seated per day were the three most predictive risk factors&#46; Adjusted odds ratios were 9&#46;23&#44; 6&#46;33 and 4&#46;03&#44; respectively &#40;p&#60;0&#46;001&#41;&#46; With an adjusted odds ratio of 1&#46;3 &#40;p&#60;&#46;001&#41;&#44; body mass index was another risk factor&#46; Family history was not statistically different between the groups and there was no specific occupation associated with the disease&#46;</p></span> <span id="ceabs40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle40">CONCLUSIONS</span><p id="spara70" class="elsevierStyleSimplePara elsevierViewall">Hairy people who sit down for more than six hours a day and those who take a bath two or less times per week are at a 219-fold increased risk for sacrococcygeal pilonidal disease than those without these risk factors&#46; For people with a great deal of hair&#44; there is a greater need for them to clean their intergluteal sulcus&#46; People who engage in work that requires sitting in a seat for long periods of time should choose more comfortable seats and should also try to stand whenever possible&#46;</p></span>"
        "secciones" => array:4 [
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
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                  \t\t\t\t">Name&#58;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Patient &#40; &#41;&#44; Control &#40; &#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">Date and hospital name&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">Age and sex&#58;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Length &#40;cm&#41;&#58;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weight &#40;kg&#41;&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Profession<a class="elsevierStyleCrossRef" href="#tfn1-cln_65p125">&#40;&#42;&#41;</a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Time spent seated per day&#58; &#60;6 hour &#40; &#41;&#44; &#8805;6 hour &#40; &#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Body hair rate&#58; hairless &#40; &#41;&#44; mildly hairy &#40; &#41;&#44; hairy &#40; &#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Number of baths in a week&#58;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Family history<a class="elsevierStyleCrossRef" href="#tfn2-cln_65p125">&#40;&#42;&#42;&#41;</a> Positive &#40; &#41;&#44; Negative &#40; &#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
          "notaPie" => array:2 [
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              "identificador" => "tfn1-cln_65p125"
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              "nota" => "<p class="elsevierStyleNotepara" id="cenpara10">The job mostly done during the two years prior to the sacrococcygeal pilonidal disease &#40;SPD&#41;&#46; If the patient had worked&#44; but not in the same job for more than six months during this time period&#44; they were considered to be an irregular worker&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tfn2-cln_65p125"
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              "nota" => "<p class="elsevierStyleNotepara" id="cenpara20">Presence of SPD in father&#44; mother&#44; brother or sister&#46;</p>"
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          ]
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          "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">Data collection form</p>"
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                  \t\t\t\t" scope="col">Unadjusted OR&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col">95&#37; CI&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
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                  \t\t\t\t" scope="col">Adjusted<a class="elsevierStyleCrossRef" href="#tfn3-cln_65p125">&#40;a&#41;</a> OR&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
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                  \t\t\t\t  " colspan="7" align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;25 &#40;Reference&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>25&#8211;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">2&#46;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">1&#46;74&#8211;2&#46;64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;56&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;20&#8211; 2&#46;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#62;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">0&#46;94&#8211;3&#46;52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;54&#8211; 2&#46;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="7" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Time Spent Seated Per Day</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;6 hour &#40;Reference&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805;6 hour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;31&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;75&#8211;3&#46;97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;22&#8211; 5&#46;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="7" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Body Hair Rate</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">37&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">1&#46;3&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">49&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="8" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Time sitting on a seat per day</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;6 hour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">258&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">44&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">72&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2264&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">67&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805;6 hour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">329&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">56&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">774&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1103&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">32&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="8" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Stiffness of Body Hair</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hairless&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1228&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">44&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1275&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mild&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">308&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">52&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1161&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">41&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1469&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">43&#46;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hairy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">232&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">39&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">390&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">622&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="8" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Number of Baths in a Week</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>3 or more&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">168&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">28&#46;62&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1913&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">68&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2081&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">61&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2 or less&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">419&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">71&#46;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">867&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1286&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">38&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="8" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Family History for Sacrococcygeal Pilonidal Disease &#40;SPD&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Positive&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">98&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">405&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">503&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black"><span class="elsevierStyleHsp" style=""></span>Negative&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">489&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="center" valign="\n
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          "en" => "<p id="spara30" class="elsevierStyleSimplePara elsevierViewall">Distribution of risk factors in the patient and control groups</p>"
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Article information

ISSN: 18075932
Original language: English

DOI:10.1590/S1807-59322010000200002

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Year/Month	Html	Pdf	Total

2024 November	3	0	3
2024 October	17	24	41
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2024 August	26	19	45
2024 July	16	12	28
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2024 March	19	14	33
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2024 January	7	5	12
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