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Editorial
In the November 2009 Issue of Clinics
Mauricio Rocha-e-Silva
Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo – São Paulo/SP, Brazil.
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="para10" class="elsevierStylePara elsevierViewall">In our November 2009 issue&#44; we highlight a prospective study by <span class="elsevierStyleBold">Soares Miguel et al&#46;</span> who assessed glucose homeostasis and weight loss in 33 morbidly obese female patients undergoing a recently introduced procedure of Silastic&#174; ring sleeve gastrectomy&#46; They found the procedure to be effective in promoting weight loss&#44; waist circumference reduction&#44; and control of glucose homeostasis&#46; We also publish seven other clinical studies and two basic research original articles&#46;</p><p id="para20" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Cobo et al&#46;</span> report on seven patients who were diagnosed between 1996 and 2008 with pemphigoid gestationis&#44; a rare autoimmune blistering disease associated with pregnancy&#46; Demographics revealed a good outcome of the newborns from affected mothers&#44; based on the absence of pemphigoid gestationis cutaneous lesions&#44; mean birth weight&#44; and normal Apgar scores and gestational age at birth&#46;</p><p id="para30" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Ribeiro et al&#46;</span> investigated the relationship between meal frequency&#44; the occurrence of vomiting and weight loss among 80 patients submitted to Roux-en-Y gastric bypass in the period up to 9 months after surgery&#46; They report that &#40;1&#41; frequent small meals were associated with a reduction in weight loss after gastric bypass and a decrease in vomiting episodes at 6 months&#44; and &#40;2&#41; that vomiting did not interfere with nutritional outcome&#46; They suggest that multiple small meals may not be advantageous after such intervention and should not be indicated unless required because of vomiting or other reasons&#46;</p><p id="para40" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Piovesan et al&#46;</span> determined the incidence of asymptomatic&#44; histologically proven prostatitis in 183 men with symptoms of benign prostate hyperplasia&#46; They also describe the correlation between asymptomatic prostatitis and prostate specific antigen density&#46; On histological examination of the surgical samples&#44; evidence of prostatitis was observed in 145 patients&#44; with no such evidence in the other 38 cases&#46; No statistically significant differences were detected between the two groups&#59; leading to the conclusion that abnormal PSA density should not be attributed to the inflammatory prostatitis process&#46;</p><p id="para50" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Aguiar Junior et al&#46;</span> retrospectively analyzed a consecutive series of 49 adult patients with advanced extremity soft tissue sarcomas that could not be resected with adequate margins during the primary resection&#46; They were treated with preoperative radiation concomitant with doxorubicin chemotherapy&#46; The five-year local recurrence-free survival&#44; metastasis-free survival and overall survival rates were 81&#46;5&#37;&#44; 46&#46;7&#37; and 58&#46;3&#37;&#44; respectively&#46; For high-grade tumors&#44; the five-year metastasis-free&#44; and overall survival rates were only 36&#46;3&#37; and 41&#46;2&#37;&#44; respectively&#46; Severe wound complications were observed in 41&#46;8&#37; of the patients who underwent surgery&#46; These complications precluded adjuvant chemotherapy in 73&#46;7&#37; &#40;14&#47;19&#41; of the patients eligible to receive it&#46; They conclude that neoadjuvant chemoradiation therapy was associated with a good local control rate&#44; but the distant relapse-free rate and overall survival rate were still poor&#46; The high rate of wound complications modified the planning of adjuvant treatment in most patients&#46;</p><p id="para60" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Tramont et al&#46;</span> conducted a cross-sectional study to evaluate the impact of ageing on the resistive and reactive properties of the respiratory system&#44; and compare the easiness of accomplishment of spirometry and forced oscillation for assessing lung function&#46; Forced oscillation was used to investigate respiratory system resistive and reactive properties&#44; while spirometry was used as a reference test&#46; Eighty normal subjects aged between 20 and 86 years were evaluated&#46; They conclude that &#40;1&#41; respiratory system resistance and dynamic compliance are not modified with ageing&#59; &#40;2&#41; respiratory system homogeneity decreases during the ageing process&#46; They state that forced oscillation is easy to perform and provides information complementary to spirometry&#46; Suggesting that this approach may be a useful alternative to conventional exams for older people are unable to adequately perform spirometric tests&#46;</p><p id="para70" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Cohen et al&#46;</span> report a descriptive&#44; quantitative study using a retrospective documental analysis regarding doctors were allegedly engaged in sexual harassment&#46; All accusations made from January 2000 to December 2005 were examined&#46; A high prevalence of male professionals committing abuse against female patients during adulthood was found&#46; Average age of the accused was 47 years &#40;range 30 &#8211; 76&#41;&#44; and ncidence was independent of education&#44; as the accused professionals came from a large variety of medical colleges&#44; without significant differences related to institution&#46; They suggest that the predominance of accusations against older professionals may occur due to the frail personality structure that allows professional acting out&#46;</p><p id="para80" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Pantoni et al&#46;</span> evaluated the heart rate variability during bi-level positive airway pressure in 20 young healthy subjects&#44; and found that acute application altered reduced parasympathetic and an increased sympathetic activity suggesting that high levels of positive pressure can significantly influence cardiovascular function&#46;</p><p id="para90" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Mascaretti et al&#46;</span> evaluated the effects of hyperoxic exposure on elastic and collagen fiber deposition in the lung interstitial matrix and in alveolarization in 28-day preterm New-Zealand-White rabbits obtained through c-section&#46; Test animals were exposed to O<span class="elsevierStyleInf">2</span> &#8805; 95&#37;&#44; while controls breathed 21&#37; O<span class="elsevierStyleInf">2</span>&#46; An increase in the alveolar size and a decrease in the alveoli number were observed among hyperoxia exposed rabbits&#44; with no differences regarding the internal alveolar surface area&#46; No difference in the density of elastic fibers was observed after high O<span class="elsevierStyleInf">2</span> exposure&#44; but there were fewer collagen fibers and an evident disorganization of fiber deposition&#46;</p><p id="para100" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Barbosa et al&#46;</span> evaluated the degree of vascular occlusion&#44; vascular recanalization&#44; and necrosis of the vascular wall caused by polyvinyl alcohol-covered polyvinyl acetate particles compared to trisacryl particles after renal embolization in 79 female albino New Zealand rabbits&#44; and found that polyvinyl alcohol-covered polyvinyl acetate particles as an embolization material exhibited an adequate tissue reaction &#40;ischemia and volumetric reduction&#41;&#44; more expressive vascular occlusion and necrosis&#44; and less recanalization than the trisacryl material&#46;</p><p id="para110" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Adam et al&#46;</span> describe effects of a diet containing repeatedly heated soy oil on the aortic tissues of 30 ovariectomized estrogen-deficient female rats&#46; They found that fresh soy oil offered protection in the estrogen-deficient state&#44; whereas repeatedly heated soy oil damaged the tunica intima and the increased in the ratio of tunica intima&#47;media thickness&#46;</p><p id="para120" class="elsevierStylePara elsevierViewall">We also publish a review on the surgical procedure of anterior hepatic transection for caudate lobectomy&#44; and three case reports&#46;</p></span>"
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Article information
ISSN: 18075932
Original language: English
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