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Letter to the Editor
MR Imaging Features of Peritoneal Adenomatoid Mesothelioma: A Case Report
Cynthia Maria Coelho LinsI, Jorge Elias JrI, Adilson Ferreira CunhaII, Valdair Francisco MugliaI, Carlos Ribeiro MonteiroI, Fábio V. ValeriIII, Omar FeresIV
I Department of Internal Medicine, Radiology Division, School of Medicine of Ribeirão Preto, University of Sao Paulo - Ribeirão Preto/SP, Brazil
II Department of Gynecology and Obstetrics, School of Medicine of São José do Rio Preto (FAMERP) - São José do Rio Preto/SP, Brazil
III Victorio Valeri Institute of Medical Diagnosis - Ribeirao Preto/SP, Brazil
IV Department of Surgery and Anatomy, School of Medicine of Ribeirão Preto, University of Sao Paulo - Ribeirão Preto/SP, Brazil, Tel.: 55 16 3602.2643
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="para10" class="elsevierStylePara elsevierViewall">Adenomatoid mesothelioma of the peritoneum &#40;AMP&#41; is a rare benign tumor originating from mesothelial cells&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> Most frequently&#44; AMP occurs between 26 and 55 years of age&#44; at a mean age of 41 years&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> In contrast to diffuse malignant mesothelioma&#44; which has been linked to asbestos exposure&#44; the etiology of AMP has not been established&#46;<a class="elsevierStyleCrossRef" href="#bib2">2</a> Only a minority of patients have symptoms related to the tumor&#46; AMP may present local recurrence&#44; but it has no potential for malignant transformation&#46;<a class="elsevierStyleCrossRef" href="#bib3">3</a> Although there are many case reports of abdominal mesotheliomas&#44; to date&#44; there have been no reports of MR imaging features of AMP&#46; In this article&#44; we present the MR imaging features of a case of AMP with histopathological correlation&#46;</p><span id="cesec10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle10">CASE REPORT</span><p id="para20" class="elsevierStylePara elsevierViewall">A 25-year-old woman presented with pelvic pain&#46; The patient had had a cesarean section 3 years before her visit and an appendectomy about 6 months earlier than her onset&#46; Routine ultrasound exam showed an expansive pelvic lesion suggesting an adnexal origin&#44; most likely an ovarian neoplasm&#44; and this finding was confirmed by two other ultrasound exams&#44; each one performed at a different facility&#46; A pelvic-abdominal MR exam was requested for lesion characterization&#46; Laboratory tests were within normal values&#44; except for CA125 of 37&#46;9 &#956;&#47;ml &#40;normal range 0&#46;0 to 35&#46;0 &#956;&#47;ml&#41;&#46;</p><span id="cesec20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle20">Imaging Findings</span><p id="para30" class="elsevierStylePara elsevierViewall">Transvaginal pelvic sonography showed a retrouterine adnexal mass extending towards the left parauterine region with a complex echotexture containing a homogeneous solid component about 5&#46;0 cm in size and small cystic areas intermingled with linear septa&#46; The mass measured 10&#46;8 &#215; 6&#46;1 &#215; 10&#46;5 cm &#40;volume of 359&#46;7 cm<span class="elsevierStyleSup">3</span>&#41;&#46; Color Doppler imaging demonstrated vascularization of the solid area and of some septa in the cystic region&#44; with a resistive index ranging from 0&#46;60 to 0&#46;70&#46; Ovaries were identified in neither ultrasound exam&#46; There was no sign of ascites &#40;<a class="elsevierStyleCrossRef" href="#fig1">Figure 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig1"></elsevierMultimedia><p id="para40" class="elsevierStylePara elsevierViewall">The MR images demonstrated a large&#44; expansive&#44; and well-delimited lesion with lobulated contours&#59; T1-weighted images showed homogeneous signal intensity predominately with a low signal&#44; whereas T2-weighted sequences were heterogeneous with small high intensity foci &#40;<a class="elsevierStyleCrossRef" href="#fig2">Figure 2</a>&#41;&#46; There was a slightly heterogeneous enhancement in post-contrast T1-weighted images that was more evident peripherally &#40;<a class="elsevierStyleCrossRef" href="#fig2">Figure 2</a>&#41;&#46; The lesion measured 9&#46;2 &#215; 7&#46;2 &#215; 8&#46;0 cm and was located close to the ovaries&#44; which were dislocated anterolaterally&#46; The contours&#44; dimensions and signal intensity of the ovaries were normal&#46; The uterus was normal in shape&#44; dimensions and signal intensity&#44; and it was also dislocated anteriorly&#46; A small amount of free fluid was present in the peritoneal cavity surrounding the lesion&#46; The upper abdominal MR evaluation showed the extension of the free peritoneal fluid and normal anatomy of abdominal organs&#46; Computed tomography of the pelvis without intravenous injection of contrast agent was performed to search for calcification and showed a low homogeneous coefficient of attenuation for the lesion&#44; ranging from &#8722; 2 to &#43;10 U&#46;H&#44; with no evidence of calcification &#40;<a class="elsevierStyleCrossRef" href="#fig3">Figure 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig2"></elsevierMultimedia><elsevierMultimedia ident="fig3"></elsevierMultimedia></span><span id="cesec30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle30">Patient outcome</span><p id="para50" class="elsevierStylePara elsevierViewall">The patient was submitted to open abdominal surgical resection of the lesion&#44; which had adherences to the rectal anterior wall but no invasion of the uterus or adnexa&#46; Macroscopic anatomopathological examination revealed various irregular fragments of brownish&#44; friable tissue that measured 15&#46;0 &#215; 12&#46;0 &#215; 4&#46;0 cm and weighed 170&#46;0 g&#46; Microscopic analysis revealed a well-differentiated mesothelial neoplasia&#44; which is detailed in <a class="elsevierStyleCrossRef" href="#tbl1">Table 1</a>&#46; Immunohistochemistry evaluation was carried out in the histological sections with an immuno-peroxidase reaction via the avidin-biotin peroxidase method&#44; with the primary antibodies calretinin &#43; CEA<span class="elsevierStyleBold">-</span> and BerEp4<span class="elsevierStyleBold">-</span> &#40;<a class="elsevierStyleCrossRef" href="#fig4">Figure 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl1"></elsevierMultimedia><elsevierMultimedia ident="fig4"></elsevierMultimedia><p id="para60" class="elsevierStylePara elsevierViewall">A follow-up MR exam revealed an expansive&#44; predominantly cystic lesion with high protein content located in the posterior cul-de-sac&#59; this lesion had shown a progressive increase in volume over 3 years and was characterized as a recurrent tumoral lesion &#40;<a class="elsevierStyleCrossRef" href="#fig5">Figure 5</a>&#41;&#46; The lesion was resected surgically&#44; and there was no sign of recurrent disease on subsequent follow-up exams&#46; The patient is currently asymptomatic&#46;</p><elsevierMultimedia ident="fig5"></elsevierMultimedia></span></span><span id="cesec40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle40">DISCUSSION</span><p id="para70" class="elsevierStylePara elsevierViewall">Mesotheliomas are rare tumors originating from mesothelial cells of serosal membranes such as the pleura&#44; peritoneum&#44;<a class="elsevierStyleCrossRef" href="#bib4">4</a> pericardium&#44; and tunica vaginalis&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> Simultaneous pleural and peritoneal involvement occurs in 30&#8211;45&#37; of cases&#44; whereas disease limited to the peritoneum occurs in 10 to 20&#37; of the patients&#46;<a class="elsevierStyleCrossRef" href="#bib5">5</a> Peritoneal mesotheliomas can be classified as benign &#40;adenomatoid&#44; fibrous&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib3">3</a>&#44;<a class="elsevierStyleCrossRef" href="#bib6">6</a> borderline &#40;multicystic&#44; well-differentiated papilliferous&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib4">4</a>&#44; <a class="elsevierStyleCrossRef" href="#bib7">7</a>&#44;<a class="elsevierStyleCrossRef" href="#bib8">8</a> and malignant &#40;epithelioid&#44; sarcomatoid or biphasic&#47;mixed&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib8">8</a> and their characteristics are described in <a class="elsevierStyleCrossRef" href="#tbl2">Table 2</a>&#46;</p><elsevierMultimedia ident="tbl2"></elsevierMultimedia><p id="para80" class="elsevierStylePara elsevierViewall">Peritoneal adenomatoid mesothelioma &#40;AMP&#41; is a benign neoplasia<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a> of unknown etiology that primarily involves the genital tract of both sexes&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a> occurring more frequently among males&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib3">3</a>&#44;<a class="elsevierStyleCrossRef" href="#bib8">8</a>&#44;<a class="elsevierStyleCrossRef" href="#bib11">11</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib13">13</a></p><p id="para90" class="elsevierStylePara elsevierViewall">We report here a case of a 25-year-old woman diagnosed with AMP that was confined to the peritoneum&#46; Among women&#44; adenomatoid tumors are more commonly encountered in the myometrium &#40;posterior wall of the uterus&#41;&#44; in the fallopian tubes&#44; in paraovarian connective tissue&#44;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib12">12</a> and rarely in the ovaries&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a> In our patient&#44; the uterus and ovaries were free of disease&#44; and the lesion was confined to the peritoneum&#46;</p><p id="para100" class="elsevierStylePara elsevierViewall">Among males&#44; in most cases the tumor is detected in the inferior pole of the epididymis&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a> but it can also involve the ejaculatory duct&#44; sperm cord&#44; tunica albuginea&#44; tunica vaginalis&#44; testicular parenchyma&#44; prostate&#44; and rarely the spermatic funiculus&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib13">13</a></p><p id="para110" class="elsevierStylePara elsevierViewall">Adenomatoid tumors have also been detected in the omentum&#44; mesentery&#44; pancreas&#44; liver&#44; bladder&#44; mediastinal lymph nodes&#44; pleura&#44; heart&#44; and adrenal glands&#46;<a class="elsevierStyleCrossRef" href="#bib3">3</a>&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#44;<a class="elsevierStyleCrossRef" href="#bib11">11</a>&#44;<a class="elsevierStyleCrossRef" href="#bib13">13</a> The cause of the apparent predominance in the genital tract when compared to other mesothelial locations has not been explained&#46;<a class="elsevierStyleCrossRef" href="#bib3">3</a> Historically&#44; adenomatoid tumors have always attracted interest regarding their histological origin&#44; and several hypotheses have been proposed&#46; Immunohistochemical studies favor mesothelial histogenesis&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a> The &#8220;adenomatoid&#8221; designation was introduced by Golden and Ash in 1945<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a> because of the arrangement of the cells in a cohesive manner&#44; forming tubules and canaliculi&#46; Four histological patterns of adenomatoid tumors have been identified and classified as adenoid&#44; angiomatoid&#44; solid or cystic&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib3">3</a> The histological pattern of the present case was classified as solid&#46; The peak incidence of this tumor is between the 3rd and 5th decades of life&#44; between 26 and 55 years &#40;mean&#58; 41 years&#41;&#44; with an extremely rare occurrence in children&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a></p><p id="para120" class="elsevierStylePara elsevierViewall">AMP is an uncommon tumor&#44;<a class="elsevierStyleCrossRef" href="#bib3">3</a> usually asymptomatic&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a> and is incidentally discovered during radiologic exams&#44; surgeries or autopsies&#46;<a class="elsevierStyleCrossRef" href="#bib3">3</a>&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a> It is typically a single polypoid or nodular small lesion &#40;2&#46;0 cm or less&#41;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib14">14</a> that can measure up to 13 cm in diameter in a few cases&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> Adenomatoid tumors are usually solid&#44; not encapsulated and often contain small cystic lesions &#40;0&#46;4 to 1&#46;5 cm&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib12">12</a> When present&#44; signs and symptoms are abdominal pain&#44; loss of weight&#44; loss of appetite&#44; nausea&#44; fluid accumulation in the peritoneal space &#40;ascites&#41;&#44; and a pelvic mass&#46;<a class="elsevierStyleCrossRef" href="#bib8">8</a></p><p id="para130" class="elsevierStylePara elsevierViewall">In the present case&#44; the tumor was 15 cm at its widest diameter on pathological examination&#44; exceeding the size of previously reported masses&#46; This might explain why the patient was symptomatic&#59; additionally&#44; after surgical resection&#44; symptoms disappeared for a period of approximately one year&#46; After that&#44; the lesion recurred&#44; and the patient was submitted to a new surgical intervention&#46; The patient has now been free of the disease for 7 years&#46;</p><p id="para140" class="elsevierStylePara elsevierViewall">Usually&#44; surgical resection is the treatment of choice for AMP&#46; Accurate diagnosis and staging are important because of the obvious therapeutic implications&#46;<a class="elsevierStyleCrossRef" href="#bib15">15</a> Although benign&#44; AMP is a source of great concern due to the differential diagnosis of malignant entities&#46;<a class="elsevierStyleCrossRef" href="#bib10">10</a></p><p id="para150" class="elsevierStylePara elsevierViewall">In the present case&#44; in view of the location of the tumor in the cul-de-sac and its histopathological characteristics &#40;cells clustered in a papillary formation&#41;&#44; it was necessary to establish a differential diagnosis with adenocarcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib1">1</a> Histology revealed medium-sized polygonal cells in an acinar&#44; tubular and papilliform cell arrangement&#44; a low mitotic index &#40;up to 1&#41;&#44; a mild grade of atypia&#44; abundant vascularization&#44; and absence of necrosis&#44; suggesting an adenomatoid tumor&#46;<a class="elsevierStyleCrossRef" href="#bib14">14</a></p><p id="para160" class="elsevierStylePara elsevierViewall">Immunohistochemistry revealed positivity for calretinin&#44; which labels mesothelial cells in 60 to 100&#37; of cases<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#44;<a class="elsevierStyleCrossRef" href="#bib13">13</a> and rarely labels adenocarcinomas &#40;0 to 28&#37;&#41;&#46; In addition&#44; the cells of the neoplasia reported here were negative for BerEp4&#44; which labels epithelial cells that are not present in mesotheliomas&#46;<a class="elsevierStyleCrossRef" href="#bib2">2</a>&#44;<a class="elsevierStyleCrossRef" href="#bib5">5</a> The present case was negative for CEA immunoreagent&#44; which frequently labels pulmonary and gastrointestinal carcinomas and is detected in only 0 to 35&#37; of serous ovarian carcinomas&#46;<a class="elsevierStyleCrossRef" href="#bib2">2</a>&#44;<a class="elsevierStyleCrossRef" href="#bib16">16</a> Thus&#44; negativity of this marker is of no help for differentiation between adenomatoid tumors and adenocarcinomas&#46; The possibility of the latter was ruled out due to immunohistochemistry compatible with an adenomatoid tumor&#44; and by MRI and laparotomy findings that revealed disease-free ovaries&#46; Another possible differential diagnosis for this case&#44; arising from its location in a cul-de-sac&#44; would be a metastatic tumor&#46; However&#44; CEA negativity and calretinin positivity do not favor this possibility&#44; as demonstrated in <a class="elsevierStyleCrossRef" href="#tbl3">Table 3</a>&#46; Other differential diagnoses are cysts of peritoneal inclusion&#44; hemangiomas&#44; lymphangiomas&#44;<a class="elsevierStyleCrossRef" href="#bib12">12</a> mesothelial hyperplasia&#44; malignant mesotheliomas&#44;<a class="elsevierStyleCrossRef" href="#bib9">9</a> and well-differentiated papilliferous mesotheliomas&#46;</p><elsevierMultimedia ident="tbl3"></elsevierMultimedia><p id="para170" class="elsevierStylePara elsevierViewall">Mesothelial hyperplasia has been associated with peritoneal insults such as hernia&#44; ectopic tubal pregnancy&#44; and abdominal cirrhosis and tuberculosis<a class="elsevierStyleCrossRef" href="#bib3">3</a> and is accompanied by adherences and chronic inflammation&#46;<a class="elsevierStyleCrossRef" href="#bib14">14</a> This entity rarely produces tumoral masses and does not have the tubulopapilliferous complex or the labyrinth architecture of mesotheliomas&#46;<a class="elsevierStyleCrossRef" href="#bib14">14</a> The differential diagnosis with malignant mesothelioma and well-differentiated papilliferous mesothelioma is made on the basis of the distinct histological characteristics of these tumors when compared to AMP&#46;<a class="elsevierStyleCrossRef" href="#bib17">17</a></p><p id="para180" class="elsevierStylePara elsevierViewall">MR has become a valuable noninvasive technique for evaluation of the female pelvis&#44;<a class="elsevierStyleCrossRef" href="#bib18">18</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib20">20</a> with advantages over computed tomography and ultrasound for diagnosis and for staging various pathological conditions of the pelvis &#40;leiomyoma&#44; adenomyosis&#44; carcinoma of the endometrium and of the uterine cervix&#44; carcinoma of the vagina&#44; ovarian cysts&#44; endometriosis&#44; teratomas&#44; polycystic ovaries&#44; and other ovarian masses&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib18">18</a>&#44;<a class="elsevierStyleCrossRef" href="#bib20">20</a></p><p id="para190" class="elsevierStylePara elsevierViewall">MR has proven to be a highly sensitive modality for characterization of pelvic masses&#44; allowing physicians to determine whether the pelvic mass is uterine or of adnexal origin and also to characterize most adnexal masses&#46;<a class="elsevierStyleCrossRef" href="#bib20">20</a> MR can also provide multiplanar information&#44; revealing additional information when compared to CT or US&#46; This is especially true along the pelvic walls and the presacral space&#46;<a class="elsevierStyleCrossRef" href="#bib18">18</a>&#44;<a class="elsevierStyleCrossRef" href="#bib20">20</a> MR is also especially useful for surgical planning<a class="elsevierStyleCrossRef" href="#bib15">15</a> and patient follow-up&#46; Low <span class="elsevierStyleItalic">et al</span><a class="elsevierStyleCrossRef" href="#bib21">21</a> studied 24 patients with suspected peritoneal tumors and found that MR had higher sensitivity&#44; specificity and accuracy than CT in the detection of tumors &#40;84&#37;&#44; 87&#37; and 86&#37;&#44; compared to 54&#37;&#44; 91&#37; and 74&#37;&#44; respectively&#44; for CT&#41; and was superior for detection of carcinomatosis and of tumors measuring less than 1 cm in diameter &#40;75&#37; to 80&#37; for MR and 22&#37; to 33&#37; for CT&#41;&#46; Post-contrast T1-weighted images with fat suppression were proven to be the most sensitive MR technique for detecting peritoneal disease&#46; MR and CT showed identical performance for detection of tumors measuring more than 2 cm and 1 to 2 cm in diameter&#46;<a class="elsevierStyleCrossRef" href="#bib21">21</a></p><p id="para200" class="elsevierStylePara elsevierViewall">Notably&#44; the high sensitivity of the MR exam could depict both ovaries as free of disease and was able to characterize the lesion as not having ovarian or uterine origin&#59; this could not be achieved by ultrasound examination&#46; Also&#44; to date&#44; we believe that this is the first case both to show MR findings for AMP and to correlate these findings to ultrasound and computed tomography&#46; Descriptions of imaging findings regarding AMP are scarce in the literature&#46; AMP seems to have no specific radiological characteristics&#44; and it is important to establish a correlation between clinical presentation and the imaging and laboratory findings&#46; At this point&#44; it is necessary to reinforce that diagnosis can only be confirmed by anatomopathology and immunohistochemistry&#46;</p></span></span>"
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          "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">Transvaginal pelvic ultrasound images &#40;A&#44;B&#41; showed a complex retrouterine mass with a homogeneous solid component &#40;&#42;&#44; B&#41; and cystic areas &#40;arrowhead&#44; A&#41; intermingled with linear septa &#40;arrow&#44; A&#41;</p>"
        ]
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          "en" => "<p id="spara20" class="elsevierStyleSimplePara elsevierViewall">Pelvic MR exam&#46; Axial GRE T1-weighted &#40;A&#41;&#44; axial TSE 512 T2-weighted &#40;B&#41;&#44; sagittal post-contrast GRE T1-weighted image and &#40;D&#41; sagittal TSE T2-weighted images&#46; There is a large&#44; expansive&#44; well-delimited lesion with lobulated contours&#59; the T1-weighted sequence shows homogeneous signal intensity predominately with a low signal&#44; and T2-weighted sequences are heterogeneous with small high-intensity foci &#40;arrow&#41;&#46; The lesion dislocated the ovaries &#40;arrowheads&#44; B&#41; anterolaterally and the uterus &#40;&#42;&#44; A&#44;C and D&#41; anteriorly&#46; After intravenous injection of paramagnetic contrast agent&#44; there was a heterogeneous enhancement of the lesion that was more evident peripherally &#40;arrowheads&#44; C&#41;</p>"
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          "en" => "<p id="spara30" class="elsevierStyleSimplePara elsevierViewall">Computed tomography with no intravenous contrast agent revealed that there was no calcification within the mass &#40;arrows&#41;</p>"
        ]
      ]
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          "en" => "<p id="spara40" class="elsevierStyleSimplePara elsevierViewall">The histopathologic section shows calretinin staining for well-differentiated mesothelial cells &#40;&#42;&#41;&#44; which confirms the mesothelial origin of the tumor</p>"
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          "en" => "<p id="spara50" class="elsevierStyleSimplePara elsevierViewall">Follow-up pelvic MR exam&#46; Axial TSE T2-weighted &#40;A&#41; and post-contrast axial GRE T1-weighted &#40;B&#41; images show a retrouterine&#44; large&#44; well-delimited cystic lesion with internal post-contrast-enhanced nodules &#40;arrows&#41; and partial septations &#40;arrowhead&#41;&#46; This lesion was surgically excised and histopathologically confirmed as to be a recidivate mesothelioma &#40;u&#44; uterus&#41;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Origin</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Primitive&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Histogenetic lineage</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mesothelial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Structural differentiation</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Well-differentiated&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Supporting tissue</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Loose &#8211; vascularized&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Predominant cell type</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medium size &#8211; Polygonal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Cell arrangement</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Acinar &#8211; Tubular &#8211; Papilliform&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Cytoplasm characteristics</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Abundant &#8211; Microvacuolized &#8211; Basophilic&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Nucleus characteristics</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medium volume &#8211; Round &#8211; Discrete nucleoli &#8211; Fine chromatin &#8211; Homogeneous chromatin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Nucleus&#47;cytoplasm ratio</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Maintained&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Extracellular material produced</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Absent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Mitotic index</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Low &#40;up to 1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Degree of necrosis</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Absent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Degree of atypy</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mild&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Cytologic &#40;nuclear&#41; grade</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Histological grade</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">I&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Capsular limits</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Absent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Tumor limits</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Poorly defined&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Vascularization</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Abundant&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Forms of infiltration</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Absent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Inflammatory infiltrate</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Present&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Predominant cells</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Lymphocytes &#8211; Histiocytes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Microcalcifications</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Present &#8211; Focal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Desmoplasia</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Absent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Hemorrhage</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Absent&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Vacuolar embolization</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Not visualized&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Lymphatic embolization</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Not visualized&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Perineural infiltration</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Not visualized&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Surgical safety margins</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Poorly defined&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara60" class="elsevierStyleSimplePara elsevierViewall">Histopathological findings of the reported case</p>"
        ]
      ]
      6 => array:7 [
        "identificador" => "tbl2"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:1 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Well-differentiated papilliferous peritoneal mesothelioma <a class="elsevierStyleCrossRef" href="#bib2">2</a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Multicystic peritoneal mesothelioma <a class="elsevierStyleCrossRef" href="#bib4">4</a>&#44; <a class="elsevierStyleCrossRef" href="#bib6">6</a>&#44; <a class="elsevierStyleCrossRef" href="#bib7">7</a>&#44; <a class="elsevierStyleCrossRef" href="#bib22">22</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib25">25</a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Fibrous peritoneal mesothelioma <a class="elsevierStyleCrossRef" href="#bib6">6</a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Malignant peritoneal mesothelioma <a class="elsevierStyleCrossRef" href="#bib16">16</a>&#44; <a class="elsevierStyleCrossRef" href="#bib26">26</a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Peritoneal adenomatoid mesothelioma &#91;1&#44;3&#44;5&#44;10&#8211;13&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Mean patient age</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">30 to 50 years &#40;46&#46;1 &#177; 13&#46;65 years&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37 years and 10 months&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">40 to 70 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26 to 55 years &#40;average of 41 years old&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Sex</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Predominance in women &#40;65&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Predominance in women of reproductive age&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Predominance in men&#44; 2 to 10 times more common than in women&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Predominance in men&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Risk factors</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No established etiology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">History of abdominal surgery &#40;53&#37; of cases&#41;&#44; endometriosis or inflammatory pelvic disease&#46;No etiologic association with asbestos&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Chronic peritoneal irritation and previous laparotomy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Exposure to asbestos &#40;15 to 30 &#37; of cases&#41;Exposure to beryllium&#44; nuclear radiation&#44; and chronic inflammatory diseases&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No established etiology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Macroscopy</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Multiple or single small nodular lesions incidentally detected during surgery &#40;0&#46;5 to 3 cm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Multiple confluent translucent cysts forming a mass&#44; without hemorrhage&#44; fat or calcifications in their walls&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Encapsulated and solid lesions&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Solitary bulky lesion&#44; usually small &#40;2cm or less&#41;&#59; with no capsule&#59; may present small cystic components&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Clinical signs and symptoms</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Asymptomatic tumor &#40;55&#37;&#41;Abdominal pain &#40;38&#46;3&#37;&#41;Ascites &#40;33&#46;3&#37;&#41;Pelvic mass &#40;11&#46;1&#37;&#41; Chronic pelvic inflammatory disease &#40;11&#46;1&#37;&#41;Constipation &#40;5&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Abdominal mass &#40;29&#37;&#41; &#43; distension&#47;abdominal pain &#40;46&#37;&#41;Asymptomatic abdominal mass &#40;18&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Abdominal pain syndromeAscitesAbdominal massAlterations of intestinal transit &#40;alternating diarrhea and constipation or symptoms simulating an obstructive crisis&#41;&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Asymptomatic &#40;incidental finding&#41;Abdominal painWeight lossLoss of appetiteNauseaAscitesPelvic mass&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Survival</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">More than five years after diagnosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mean survival of 8&#8211;12 months after diagnosis <span class="elsevierStyleSup">&#40;10&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Treatment</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Surgical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">The tumor is not sensitive to chemotherapy or radiotherapy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Surgical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cytoreduction surgery with extensive peritonectomy and perioperative intraperitoneal chemotherapy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Surgical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Location</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26&#37; in abdominal or pelvic organs22&#37; in the omentum16&#37; on the pelvic wall14&#37; in the mesentery14&#37; in the peritoneum8&#37; in the Douglascul-de-sac&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Genital tract of both sexes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Number of reported cases</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">41 cases&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">130 cases&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15 cases&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#8211;2 cases&#47;million inhabitants&#47;year&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Prognosis</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Possibility of malignant transformation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Local recurrence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Local recurrence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Local recurrence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Local recurrence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Differential diagnosis</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Serous tumor of the ovarian surfaceMetastatic tumor usually of the gastrointestinal tract&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cystic lymphangiomaEndometriosisCystoadenoma and cystoadenocarcinoma of the ovaryTeratomaPeritoneal pseudomixomaNecrotic leiomyoma - LeiomyosarcomaPeritoneal inclusion cyst&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Peritoneal tuberculosisPeritoneal carcinomatosis Peritoneal lymphomaMetastases of an ovarian carcinoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Malignant mesotheliomaMesothelial hyperplasiaWell-differentiated papilliferous peritoneal mesotheliomaMetastases&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara70" class="elsevierStyleSimplePara elsevierViewall">Features of mesothelioma-type tumors as reported in the literature</p>"
        ]
      ]
      7 => array:7 [
        "identificador" => "tbl3"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:1 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Adenocarcinomas &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Mesotheliomas &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">CEA</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">90&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">B72&#46;3</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">BEREP4</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">90&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">CD15&#40;LEU-M1&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">58&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#8211;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Calretinin</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#8211;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">42&#8211;100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara80" class="elsevierStyleSimplePara elsevierViewall">Positivity of immunohistochemical markers in adenocarcinomas and mesotheliomas<a class="elsevierStyleCrossRef" href="#bib11">11</a>&#44; <a class="elsevierStyleCrossRef" href="#bib25">25</a></p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "REFERENCES"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "cebibsec10"
          "bibliografiaReferencia" => array:26 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multicentric adenomatoid tumors involving uterus&#44; ovary&#44; and appendix"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => """
                              S Hanada \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              Y Okumura \n
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                              """
                            2 => """
                              K Kaida \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1341-8076.2003.00102.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Obstet Gynaecol Res"
                        "fecha" => "2003"
                        "volumen" => "29"
                        "paginaInicial" => "234"
                        "paginaFinal" => "238"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12959144"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Well-differentiated papillary mesothelioma of the peritoneum&#58; a separate entity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => """
                              K Hoekman \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              G Tognon \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              EK Risse \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              CA Bloemsma \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              JB Vermorken \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/0959-8049(95)00574-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Cancer"
                        "fecha" => "1996"
                        "volumen" => "32A"
                        "paginaInicial" => "255"
                        "paginaFinal" => "258"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8664037"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple adenomatoid tumours in the liver and peritoneum"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => """
                              SJ Hayes \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              P Clark \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              R Mathias \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              L Formela \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              J Vickers \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              GR Armstrong \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Clin Pathol"
                        "fecha" => "2007"
                        "volumen" => "60"
                        "paginaInicial" => "722"
                        "paginaFinal" => "724"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Best cases from the AFIP&#58; multicystic mesothelioma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => """
                              WL Wong \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              TA Johns \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              WG Herlihy \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              HL Martin \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/rg.241035068"
                      "Revista" => array:6 [
                        "tituloSerie" => "Radiographics"
                        "fecha" => "2004"
                        "volumen" => "24"
                        "paginaInicial" => "247"
                        "paginaFinal" => "250"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14730049"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
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