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Inicio Enfermedades Infecciosas y Microbiología Clínica Infección por Staphylococcus lugdunensis: presentación de trece casos
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Vol. 19. Issue 10.
Pages 475-478 (December 2001)
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Vol. 19. Issue 10.
Pages 475-478 (December 2001)
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Infección por Staphylococcus lugdunensis: presentación de trece casos
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Paloma Sánchez1, Victoria Buezas, Juan Ramón Maestre
Servicio de Microbiología. Hospital Universitario 12 de Octubre
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Introducción

S. lugdunensis es un estafilococo coagulasa negativa asociado a infecciones como endocarditis de evolución agresiva, abscesos de repetición e infecciones oportunistas

Material y métodos

Se estudiaron los aislamientos de S. lugdunensis en nuestro hospital, durante tres años (1997-2000). Se analizó el factor de afinidad para el fibrinógeno y la coagulasa libre en tubo. La identificación se realizó por los sistemas Crystal GPID (Becton Dickinson) y Wider (Soria Melguizo). El antibiograma se hizo con paneles Wider. Se revisaron las historias clínicas de los pacientes con aislamiento de S. lugdunensis

Resultados

Se obtuvieron trece aislamientos de S. lugdunensis de las siguientes muestras: abscesos (9), heridas quirúrgicas (2), hemocultivo (1) y orina (1). En diez casos el cultivo fue puro, y en tres mixto. Dos casos fueron excluidos por considerar que S. lugdunensis no estaba asociado a la patología. La localización de las lesiones fue: inguinal (4), glúteo (2), mama (2), pared abdominal (1), pie (1), desconocido (1). Diez de los trece aislamientos (76%) presentaban factor de afinidad para el fibrinógeno. Fueron sensibles a la penicilina 11/13 (84,6%). En un caso, la cepa era productora de betalactamasa (7,6%) y en otro resistente a meticilina (7,6%)

Conclusiones

Observamos que S. lugdunensis se asocia a infecciones de piel y tejidos blandos, especialmente abscesos. La infección aparece con mayor frecuencia en pacientes neoplásicos, como sucedió en tres casos de nuestra serie. Insistimos en la necesidad de llevar a cabo una correcta identificación de S. lugdunensis. El aislamiento de un estafilococo coagulasa negativa no debe tranquilizarnos, al menos hasta descartar una especie potencialmente patógena

Palabras clave:
Staphylococccus lugdunensis
estafilococos coagulasa negativa
infección
abscesos
Introduction

Staphylococcus lugdunensis is a coagulasenegative staphylococcus associated with infections such as aggressive endocarditis, repeated abscess formation and oportunist infections

Materials and methods

S. lugdunensis isolates recovered at our hospital during three years (1997-2000) were studied. The fibrinogen affinity factor and tube freecoagulase were analysed. The identification was made by the Crystal GPID (Becton-Dickinson) and Wider (Soria Melguizo) systems. Antibiotic sensitivity testing was performed with Wider panels. The clinical records of patients with S. lugdunensis recovered were studied

Results

Thirteen S. Lugdunensis isolates were recovered from the following sources: abscess (9), surgical wound (2), blood culture (1), and urine (1). In ten cases the microorganism was obtained in pure culture; in the remaining three cases, S. lugdunensis grew in mixed culture. Two cases were excluded, as S. lugdunensis was considered not to be associated with the clinicial condition. Lesions were located at: inguinal region (4), gluteal region (2), breast (2), abdominal wall (1), foot (1),unknown (1). Tent of the 13 isolates (76%) had fibrinogen affinity factor. Penicillin sensitivity was observed in 11/13 strains (84.6%). In one case, the isolate was betalactamase producer (7.6%); and in other case, the isolate was resistant to methicillin (7.6%)

Conclusions

In this study we observed that S. lugdunensis is associated with skin and sof tisuee infections, particulary abscess formation. The infection occurs most frequently in cancer patients, as observed in three cases in our series. The necessity of correctly identifying S. Lugdunensis is underscored. The recovery of coagulase-negative staphylococci should not reassure us unless a potentially pathogen species has been ruled out

Key words:
Staphylococcus lugdunensis
coagulasenegative staphylococci
infection
abscesses
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Copyright © 2001. Elsevier España, S.L.. Todos los derechos reservados
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