metricas
covid
Buscar en
Enfermedades Infecciosas y Microbiología Clínica
Toda la web
Inicio Enfermedades Infecciosas y Microbiología Clínica Portadores nasales de Staphylococcus aureus resistente a la meticilina entre niÃ...
Journal Information
Vol. 19. Issue 8.
Pages 367-370 (October 2001)
Share
Share
Download PDF
More article options
Vol. 19. Issue 8.
Pages 367-370 (October 2001)
Full text access
Portadores nasales de Staphylococcus aureus resistente a la meticilina entre niños cubanos que asisten a círculos infantiles
Visits
11192
Gilda Toraño1
Corresponding author
gilda@ipk.sld.cu

Correspondencia: MsC G. Toraño.Instituto Pedro Kourí.Autopista Novia del Mediodía km 6 1/2 Apartado 601.Marianao 13. Ciudad de la Habana. Cuba
, Dianelys Quiñones, Ibis Hernández, Tatiana Hernández, Isis Tamargo, Susana Borroto
Laboratorio de Infecciones Respiratorias Agudas Bacterianas. Instituto Pedro Kourí. Ciudad de la Habana, Cuba
This item has received
Article information
Fundamento

Recientes pero escasos informes de cepas de Staphylococcuss aureus resistentes a la meticilina (SARM) entre niños no expuestos a los factores de riesgos asociados con su adquisición, nos indujeron a investigar su circulación en la comunidad

Pacientes y Métodos

Durante los meses de septiembre y octubre de 1997 se tomaron exudados nasales y faríngeos a 358 niños menores de 5 años, atendidos en tres círculos infantiles del municipio Marianao de la Ciudad de La Habana, Cuba. Las cepas de S. aureus aisladas fueron caracterizadas por susceptibilidad a antimicrobianos utilizando el método de Kirby-Bauer. Se confirmó la resistencia a la meticilina a través del método “Oxacillin Salt-Agar Screening-Plate” recomendado por el Comité Nacional de Procedimientos Estándar del Laboratorio Clínico

Resultados

El 18,7% de los niños portaban cepas de S. aureus en el tracto respiratorio superior. En el 2,2% eran cepas de SARM. Los índices más altos de resistencia se revelaron para la eritromicina (50,7%) y tetraciclina (29,9%). Todas las cepas fueron susceptibles a la ciprofloxacina

Conclusiones

Nuestros resultados proporcionan evidencias sobre el aislamiento de cepas de SARM entre niños sanos atendidos en círculos infantiles, e indican la posibilidad de que éstas se establezcan y diseminen de forma acelerada en la comunidad

Palabras clave:
Staphylococcus aureus resistentes a la meticilina
portadores nasales
Background

Recent but scarce reports of methicillin-resistant Staphylococcus aureus strains (MRSA) among children without risk factos associated with its acquisition promted us to investigate its presence in the community

Patients and Methods

During the September and October months in 1997, nasal and pharyngeal swabs were obtained from 358 children aged less than five years who attended three day-care centers in the Marianao Area, La Habana City, Cuba. The isolated S. aureus strains were characterized for antimicrobial sensitivity using the Kirby-Bauer method. Methicillin resistance was confirmed by te ˝Oxacillin Salt-Agar Screening-Plate˝ method recommended by the National Committee for Clinical Laboratory Standards

Results

18.7% of children were carriers of S. aureus in the upper respiratory tract; 2.2% of children carried MRSA strains. The highest resistance levels corresponded to erythromycin (50.74%) and tetracycline (29.9%). All tested strains were sensitive to ciprofloxacin

Conclusions

Our results provide evidence on the recovery of MRSA strains among healthy children attending daycare centers and are suggestive of a rapid colonization and spread of these microorganisms in the community.

Key words:
Methicillin-resistant Staphylococcus aureus
nasal carriers
Full text is only aviable in PDF
Bibliografía
[1.]
J. Boyce.
Meticillin-resistant Staphylococcus aureus: detection, epidemiology, and control measures.
Infect Dis Clin North Am, 3 (1989), pp. 901-913
[2.]
J. Boyce.
Are the epidemiology and microbiology of Methicillin-resistant Staphylococcus aureus changing?.
JAMA, 279 (1998), pp. 623-624
[3.]
Y. Nur, M. Vandenbergh, M. Yusuf, A. Van Belkum, H. Verbrugh.
Nasal Carriage of Multiresistant Staphylococcus aureus Among Health Care Workers and Pediatric Patient in Two Hospitals in Mogadishu, Somalia.
J Infect Dis, 1 (1997), pp. 186-191
[4.]
M. Casewell, R. Hell.
The Carrier State: Methicillin-resistant Staphylococcus aureus.
J Antimicrob Chemother, 18 (1986), pp. 1-12
[5.]
D. Craven, A. Rixigen, T. Goularte, W. McCabe.
Meticillin-resistant Staphylococcus aureus bacteremia linked to intravenous drug abusers using galery.
Am J Med, 80 (1986), pp. 770-776
[6.]
M. Layton, W. Hierholzer, J. Patterson.
The evolving epidemiology of meticillin-resistant Staphylococcus aureus at a university hospital.
Infect Control Hosp Epidemiol, 16 (1995), pp. 12-17
[7.]
P. Adcock, P. Pastor, F. Medley, J. Patterson, T. Murphy.
Methicillin-Resistant Staphylococcus aureus in two Child Care Centers.
J Infect Dis, 178 (1998), pp. 577-580
[8.]
W. Kloos, T. Barrceman.
Staphylococcus and Micrococcus.
Manual of Clinical Microbiology (6th ed), pp. 282-298
[9.]
National Committee for Clinical Laboratory Standars. Performance Standars for antimicrobial disk Susceptibility Test. NCCLS Document M2-A7. Villanova, Pensylvania: National Comittee for Clinical Laboratory Standars, 2000
[10.]
National Committee for Clinical Laboratory Standars. Methods for dilution antimicrobial susceptibility test for bacteria that grow aerobicaly. NCCLS Document M7-A5. Villanova, Pensylvania: National Comittee for Clinical Laboratory Standars, 2000
[11.]
H. Hernández.
Resfriado común.
Infecciones respiratorias en niños, pp. 167-180
[12.]
J. Shuter, V. Hatcher, F. Lowy.
Staphylococcus aureus Binding to Human Nasal Mucin.
Infect Inmun, Jan (1996), pp. 310-318
[13.]
M. Casewell.
The Nose: an underestimated source of Staphylococcus aureus causing wound infection.
J Hosp Infect, 40 (1998), pp. S3-S11
[14.]
I. Hudson.
The Efficacy of Intranasal Mupirocin in The prevention of Staphylococcal Infections: a review of recent experience.
J Hosp Infect, 27 (1994), pp. 81-98
[15.]
D. Bibel, R. Aly, H. Shinefield, H. Maibach, W. Straus.
Importance of the Keratinized Epithelial Cell in Bacterial Adherence.
J Invest Dermatol, 79 (1982), pp. 250-253
[16.]
A. Biesbrok, M. Reddy, M. Levine.
Interaction of Salivary Mucin-Secretory Inmunogloblin A complex With Mucosal Pathogens.
Infect Immun, 59 (1991), pp. 3.492-3.497
[17.]
H. Krivan, D. Roberts, V. Ginsburg.
Many Pulmonary Pathogenic Bacteria Bend Specifically to The Carbohydrate Secuence Gal Nace1-4 Gal Found in Some Glycolipids.
Proc Natl Acad Sci USA, 85 (1988), pp. 6.157-6.161
[18.]
A. Hakansson, A. Kidd, G. Wadell, H. Sabharwal, C. Svanborg.
Adenovirus Infection Enhances In Vitro Adherence of Streptococcus pneumoniae.
Infect Immun, 62 (1994), pp. 2.707-2.714
[19.]
Cancio R. Detección de virus Respiratorios en Ciudad de La Habana durante el período 1995-1997. Tesis para optar por el Título de Especialista de Primer Grado en Microbilogía. Ciudad de la Habana,1998
[20.]
M. Coimbra, L. Texeira, R. Ramos, S. Predari, L. Castellano, A. Famiglietti, et al.
Spread of the Brazilian clone of a multiresistent MRSA in two cities in Argentina.
J Med Microbiol, 49 (2000), pp. 187-192
[21.]
M. Vardhan, D. Agarwal, P. Hunter.
Meticillin-resistant Staphylococcus aureus in Delhi teaching hospital.
J Hosp Infect, 46(2 (2000), pp. 158-159
[22.]
B. Herold, L. Inmuergluck, M. Maranan.
Commuunity-Acquiered Methicillin-resistant Staphylococcus aureus in Children with No Identified Predisposing Risk.
JAMA, 279 (1998), pp. 623-624
[23.]
C. Hsu.
Serial Survey of Methicillin-Resistant Staphylococcus aureus Nasal Carriage Among Residents in a Nursing Home.
Infect Control Hosp Epidemiol, 12 (1991), pp. 416-421
[24.]
S. Bradley, M. Terpenning, M. Ramsey.
Meticillin resistant staphylococcus aureus: colonization and infection in a long-term care facility.
Ann Intern Med, 115 (1991), pp. 417-422
[25.]
S. Holmes, A. Morron, L. Pic Kening.
Children care practices: effets of social change on the epidemiology of infections diseases and antibiotic resistance.
Epidemiol Rev, 18 (1996), pp. 10-28
[26.]
M. Sanford, A. Widmen, M. Bale, R. Jones, R. Weszel.
Efficient Detection and Long-term Persistence of the Carriage of Methicillin-resistant Staphylococcus aureus.
Clin Infect Dis, (1994), pp. 1.123-1.128
[27.]
F. Barrett, R. Mc Geher, M. Finland.
Meticillin-Resistant Staphylococcus aureus at Boston City Hospital: bcaterilogic and epidemiologic observations.
N Engl J Med, 279 (1968), pp. 441-448
Copyright © 2001. Elsevier España, S.L.. Todos los derechos reservados
Download PDF
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos