Scientific letter
Taeniasis in a Spanish girl
Teniasis en una niña española
Carla Muñoz-Antolí
, Raimundo Seguí, M. José Irisarri-Gutiérrez, Rafael Toledo, José Guillermo Esteban
Corresponding author
Departamento de Parasitología, Facultad de Farmacia, Universitat de València, Burjassot, Valencia, Spain
Read
3794
Timeswas read the article
381
Total PDF
3413
Total HTML
Share statistics
array:24 [ "pii" => "S2444382417301542" "issn" => "24443824" "doi" => "10.1016/j.gastre.2017.10.003" "estado" => "S300" "fechaPublicacion" => "2017-11-01" "aid" => "1064" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2016" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Gastroenterol Hepatol. 2017;40:626-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 64 "formatos" => array:3 [ "EPUB" => 1 "HTML" => 46 "PDF" => 17 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0210570516301005" "issn" => "02105705" "doi" => "10.1016/j.gastrohep.2016.07.005" "estado" => "S300" "fechaPublicacion" => "2017-11-01" "aid" => "1064" "copyright" => "Elsevier España, S.L.U., AEEH y AEG" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Gastroenterol Hepatol. 2017;40:626-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 289 "formatos" => array:2 [ "HTML" => 194 "PDF" => 95 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científica</span>" "titulo" => "Teniasis en una niña española" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "626" "paginaFinal" => "628" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Taeniasis in a Spanish girl" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 844 "Ancho" => 880 "Tamanyo" => 119248 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Huevos de <span class="elsevierStyleItalic">Taenia</span> encontrados en el test de Graham (escala: 50<span class="elsevierStyleHsp" style=""></span>μm).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Carla Muñoz-Antolí, Raimundo Seguí, M. José Irisarri-Gutiérrez, Rafael Toledo, José Guillermo Esteban" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Carla" "apellidos" => "Muñoz-Antolí" ] 1 => array:2 [ "nombre" => "Raimundo" "apellidos" => "Seguí" ] 2 => array:2 [ "nombre" => "M. José" "apellidos" => "Irisarri-Gutiérrez" ] 3 => array:2 [ "nombre" => "Rafael" "apellidos" => "Toledo" ] 4 => array:2 [ "nombre" => "José Guillermo" "apellidos" => "Esteban" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2444382417301542" "doi" => "10.1016/j.gastre.2017.10.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382417301542?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570516301005?idApp=UINPBA00004N" "url" => "/02105705/0000004000000009/v1_201710270226/S0210570516301005/v1_201710270226/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S244438241730158X" "issn" => "24443824" "doi" => "10.1016/j.gastre.2017.10.006" "estado" => "S300" "fechaPublicacion" => "2017-11-01" "aid" => "1147" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "ssu" "cita" => "Gastroenterol Hepatol. 2017;40:629-40" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 151 "formatos" => array:3 [ "EPUB" => 1 "HTML" => 85 "PDF" => 65 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review</span>" "titulo" => "Recommendations of everolimus use in liver transplant" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "629" "paginaFinal" => "640" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Recomendaciones de uso de everolimus en el trasplante hepático" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 3117 "Ancho" => 2106 "Tamanyo" => 255358 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Everolimus management in de novo patients.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Angel Rubín Suárez, Itxarone Bilbao Aguirre, Javier Fernández-Castroagudin, José Antonio Pons Miñano, Magdalena Salcedo Plaza, Evaristo Varo Pérez, Martín Prieto Castillo" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Angel" "apellidos" => "Rubín Suárez" ] 1 => array:2 [ "nombre" => "Itxarone" "apellidos" => "Bilbao Aguirre" ] 2 => array:2 [ "nombre" => "Javier" "apellidos" => "Fernández-Castroagudin" ] 3 => array:2 [ "nombre" => "José Antonio" "apellidos" => "Pons Miñano" ] 4 => array:2 [ "nombre" => "Magdalena" "apellidos" => "Salcedo Plaza" ] 5 => array:2 [ "nombre" => "Evaristo" "apellidos" => "Varo Pérez" ] 6 => array:2 [ "nombre" => "Martín" "apellidos" => "Prieto Castillo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210570517301310" "doi" => "10.1016/j.gastrohep.2017.05.008" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210570517301310?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S244438241730158X?idApp=UINPBA00004N" "url" => "/24443824/0000004000000009/v1_201711260719/S244438241730158X/v1_201711260719/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2444382417301657" "issn" => "24443824" "doi" => "10.1016/j.gastre.2017.10.011" "estado" => "S300" "fechaPublicacion" => "2017-11-01" "aid" => "1065" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Gastroenterol Hepatol. 2017;40:625-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 48 "formatos" => array:3 [ "EPUB" => 1 "HTML" => 17 "PDF" => 30 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific letter</span>" "titulo" => "Intraperitoneal splenosis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "625" "paginaFinal" => "626" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Esplenosis Intraperitoneal" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1326 "Ancho" => 2500 "Tamanyo" => 282405 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Multiple intraperitoneal nodules of various sizes. Morphologically and size wise they are compatible with splenosis (white arrows).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Maria Antonia Payeras Capó, Jaume Ponce Taylor, Alicia Erimeiku Barahona, Carmen de Juan García, Carmen Garrido Duran" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Maria Antonia" "apellidos" => "Payeras Capó" ] 1 => array:2 [ "nombre" => "Jaume Ponce" "apellidos" => "Taylor" ] 2 => array:2 [ "nombre" => "Alicia Erimeiku" "apellidos" => "Barahona" ] 3 => array:2 [ "nombre" => "Carmen" "apellidos" => "de Juan García" ] 4 => array:2 [ "nombre" => "Carmen Garrido" "apellidos" => "Duran" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382417301657?idApp=UINPBA00004N" "url" => "/24443824/0000004000000009/v1_201711260719/S2444382417301657/v1_201711260719/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific letter</span>" "titulo" => "Taeniasis in a Spanish girl" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "626" "paginaFinal" => "628" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Carla Muñoz-Antolí, Raimundo Seguí, M. José Irisarri-Gutiérrez, Rafael Toledo, José Guillermo Esteban" "autores" => array:5 [ 0 => array:4 [ "nombre" => "Carla" "apellidos" => "Muñoz-Antolí" "email" => array:1 [ 0 => "carla.munoz@uv.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Raimundo" "apellidos" => "Seguí" ] 2 => array:2 [ "nombre" => "M. José" "apellidos" => "Irisarri-Gutiérrez" ] 3 => array:2 [ "nombre" => "Rafael" "apellidos" => "Toledo" ] 4 => array:2 [ "nombre" => "José Guillermo" "apellidos" => "Esteban" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Departamento de Parasitología, Facultad de Farmacia, Universitat de València, Burjassot, Valencia, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Teniasis en una niña española" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1137 "Ancho" => 850 "Tamanyo" => 86757 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Gravid ring of <span class="elsevierStyleItalic">Taenia saginata</span>/<span class="elsevierStyleItalic">Taenia asiatica</span> rinsed and mounted with Amann's lactophenol between two slides (scale: 3<span class="elsevierStyleHsp" style=""></span>cm).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Humans, the only definitive host, contract taeniasis by consuming raw or undercooked pork or beef infected with the cysticercus, which takes two to three months to develop into an adult tapeworm in the intestine.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">1</span></a> Although cases are isolated and not very common, this infection is autochthonous in Spain. However, it is not considered a public health problem as only sporadic cases imported from low-income countries have been identified.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">2,3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">In April 2015, an eight-year-old girl from Valencia (Spain) was found to have whitish structures in her underwear. The girl was administered mebendazole 20<span class="elsevierStyleHsp" style=""></span>mg/ml for four days, which was repeated at two weeks by medical prescription against worm infestations. This treatment was repeated in July and October 2015 without eliminating the structures. Metronidazole 125<span class="elsevierStyleHsp" style=""></span>mg/5<span class="elsevierStyleHsp" style=""></span>ml, three times a day for one week was prescribed. Given the persistence of the structures, another paediatrician was consulted, who recommended the administration of a single dose of pyrantel 11<span class="elsevierStyleHsp" style=""></span>mg/kg for four days followed by coprological analysis. The analysis, which was performed in November 2015, was positive for “dog tapeworm”, or <span class="elsevierStyleItalic">Dipylidium caninum</span>, infestation. The paediatrician recommended treatment either with niclosamide or praziquantel. Given the unusual and foreign nature of the medication requested, the pharmacist referred the child to the Department of Parasitology of the University of Valencia's Pharmacy Faculty, where three serial stool samples and three pieces of adhesive tape (Graham's test) were analysed on consecutive days.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The macroscopic observation of numerous isolated long whitish structures (11.4–13.7<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>4.0–4.4<span class="elsevierStyleHsp" style=""></span>mm) was suggestive of <span class="elsevierStyleItalic">Taenia</span> proglottids. The faecal analysis revealed the presence of multiple yellowish-brown spherical eggs with a thick shell, measuring 35.0–37.5<span class="elsevierStyleHsp" style=""></span>μm in diameter, which were radially striated and contained a six-hooked embryo (hexacanth) known as an oncosphere. Graham's test was negative for pinworm eggs (<span class="elsevierStyleItalic">Enterobius vermicularis</span>), although multiple <span class="elsevierStyleItalic">Taenia</span> eggs were identified (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The microscopic analysis of a proglottid, mounted with Amann's lactophenol between two slides, confirmed the presence of multiple (more than 15) primary lateral branches on either side of the central uterine axis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>), with the genital pore located on the side, confirming the diagnosis of <span class="elsevierStyleItalic">Taenia saginata</span>/<span class="elsevierStyleItalic">Taenia asiatica</span>. The girl's parents and her twin sister had no parasitic infestation. The oral administration of 50<span class="elsevierStyleHsp" style=""></span>mg/kg of paromomycin sulfate divided over three doses/day was prescribed after identification of the cestode in December 2015. The parasitology stool tests conducted in January and February after treatment were negative.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The eggs in the faeces were identified as the genus <span class="elsevierStyleItalic">Taenia</span>. Specific identification was confirmed by analysis of the gravid proglottids with permanent staining or with lactophenol, to reveal the number of lateral uterine branches or to ascertain whether the proglottids spontaneously emerged from the anal orifice or were eliminated with faeces. The case in question without doubt concerns <span class="elsevierStyleItalic">T. saginata</span>/<span class="elsevierStyleItalic">T. asiatica</span> as both species have the same morphological characteristics,<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">4</span></a> and they can only be differentiated by molecular methods.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">5–7</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The child may have become infected during a stay in France, as her parents said that they went to visit her grandparents in February 2015, who regularly eat steak tartare (raw beef mixed with raw egg yolk and spices). This information may be relevant when it comes to establishing the epidemiological chain of the case given that the girl's French grandfather was treated for taeniasis two years previously. Furthermore, identifying France as the possible source of infection is not surprising given that the estimated mean annual prevalence of human taeniasis in the country is 0.11%.<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">8</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">The girl's lack of symptoms is consistent with other patients as the pathogenesis of taeniasis is very mild, with symptoms associated with abdominal pain, bloating, diarrhoea, nausea and anorexia.<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">9</span></a> The finding of proglottids in the patient's underwear can be explained by the fact that <span class="elsevierStyleItalic">T. saginata</span>/<span class="elsevierStyleItalic">T. asiatica</span> can move independently, which means they can actively emerge without having to be passed. When the proglottids crack open upon leaving the body, their eggs can become adhered to the perianal area, which explains their detection in Graham's test.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Praziquantel (5–10<span class="elsevierStyleHsp" style=""></span>mg/kg single-dose) and niclosamide (50<span class="elsevierStyleHsp" style=""></span>mg/kg single-dose, up to a maximum of 2<span class="elsevierStyleHsp" style=""></span>g) are the drugs of choice.<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">10</span></a> The fact that both antiparasitics are considered to be foreign drugs meant that paromomycin sulfate had to be used as it is available in the pharmacies.<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">11</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">It should be noted that cooking meat for longer or freezing it at −20<span class="elsevierStyleHsp" style=""></span>°C for at least 12<span class="elsevierStyleHsp" style=""></span>h would be sufficient to prevent infection.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0045" class="elsevierStylePara elsevierViewall">Project No. RD12/0018/0013, <span class="elsevierStyleItalic">Red de Investigación Cooperativa en Enfermedades Tropicales</span> (Tropical Diseases’ Cooperative Research Network, RICET), 4th National R&D&I Programme 2008-2011, <span class="elsevierStyleItalic">ISCIII-Subdirección General de Redes y Centros de Investigación Cooperativa</span> (Carlos III Health Institute—Subdirectorate General of Cooperative Research Centres and Networks) and FEDER (Spanish Federation of Rare Diseases), <span class="elsevierStyleItalic">Ministerio de Salud y Consumo</span> (Ministry of Health and Consumer Affairs), Madrid, Spain.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Muñoz-Antolí C, Seguí R, Irisarri-Gutiérrez MJ, Toledo R, Esteban JG. Teniasis en una niña española. Gastroenterol Hepatol. 2017;40:626–628.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 844 "Ancho" => 880 "Tamanyo" => 113894 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Taenia</span> eggs found in Graham's test (scale: 50<span class="elsevierStyleHsp" style=""></span>μm).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1137 "Ancho" => 850 "Tamanyo" => 86757 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Gravid ring of <span class="elsevierStyleItalic">Taenia saginata</span>/<span class="elsevierStyleItalic">Taenia asiatica</span> rinsed and mounted with Amann's lactophenol between two slides (scale: 3<span class="elsevierStyleHsp" style=""></span>cm).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:11 [ 0 => array:3 [ "identificador" => "bib0060" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A glance at <span class="elsevierStyleItalic">Taenia saginata</span> infection, diagnosis, vaccine, biological control and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.V. Silva" 1 => "J.M. Costa-Cruz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infect Disord Drug Targets" "fecha" => "2010" "volumen" => "10" "paginaInicial" => "313" "paginaFinal" => "321" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20701576" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0065" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology and transmission of cysticercosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. López-Velez" 1 => "A. García Camacho" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Clin Esp" "fecha" => "1997" "volumen" => "197" "paginaInicial" => "602" "paginaFinal" => "603" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9411562" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0070" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Taenia saginata</span>: an imported case" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.F. López-Caleya" 1 => "S.N. Contreras" 2 => "L. Martín-Rodrigo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Esp Enferm Dig" "fecha" => "2015" "volumen" => "107" "paginaInicial" => "440" "paginaFinal" => "441" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26140639" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0075" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lights and shadows of the <span class="elsevierStyleItalic">Taenia asiatica</span> life cycle and pathogenicity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.T. Galán-Puchades" 1 => "M.V. Fuentes" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/2229-5070.122114" "Revista" => array:6 [ "tituloSerie" => "Trop Parasitol" "fecha" => "2013" "volumen" => "3" "paginaInicial" => "114" "paginaFinal" => "119" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24470994" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0080" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential diagnosis of <span class="elsevierStyleItalic">Taenia saginata</span> and <span class="elsevierStyleItalic">Taenia saginata asiatica</span> taeniasis through PCR" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L.M. González" 1 => "E. Montero" 2 => "N. Morakote" 3 => "S. Puente" 4 => "J.L. Díaz de Tuesta" 5 => "T. Serra" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.diagmicrobio.2004.03.013" "Revista" => array:6 [ "tituloSerie" => "Diagn Microbiol Infect Dis" "fecha" => "2004" "volumen" => "49" "paginaInicial" => "183" "paginaFinal" => "188" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15246508" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0085" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential diagnosis of <span class="elsevierStyleItalic">Taenia asiatica</span> using multiplex PCR" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H.K. Jeon" 1 => "J.Y. Chai" 2 => "Y. Kong" 3 => "J. Waikagul" 4 => "B. Insisiengmay" 5 => "H.J. Rim" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.exppara.2008.10.014" "Revista" => array:6 [ "tituloSerie" => "Exp Parasitol" "fecha" => "2009" "volumen" => "121" "paginaInicial" => "151" "paginaFinal" => "156" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19017531" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0090" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Loop-mediated isothermal amplification method for differentiation and rapid detection of <span class="elsevierStyleItalic">Taenia</span> species" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Nkouawa" 1 => "Y. Sako" 2 => "M. Nakao" 3 => "K. Nakaya" 4 => "A. Ito" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1128/JCM.01573-08" "Revista" => array:6 [ "tituloSerie" => "J Clin Microbiol" "fecha" => "2009" "volumen" => "47" "paginaInicial" => "168" "paginaFinal" => "174" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19005142" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0095" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "192 pp." "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Morbidité et mortalité dues aux maladies infectieuses d’origine alimentaire en France (INVS)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "French Institute for Public Health Surveillance" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:1 [ "fecha" => "2003" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0100" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "Available from: <span class="elsevierStyleInterRef" id="intr0010" href="https://www.seimc.org/contenidos/ccs/revisionestematicas/parasitologia/Cestintes.pdf">https://www.seimc.org/contenidos/ccs/revisionestematicas/parasitologia/Cestintes.pdf</span> [accessed 15.6.16]" "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnóstico de las teniasis intestinalis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. Orta" 1 => "M.R. Guna" 2 => "J.L. Pérez" 3 => "C. Gimeno" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:2 [ "fecha" => "2004" "editorial" => "Programa Control Calidad SEIMC" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0105" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "[Treatment of diseases caused by parasites]" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.A. Pérez-Molina" 1 => "M. Díaz-Menéndez" 2 => "A. Pérez-Ayala" 3 => "F. Ferrere" 4 => "B. Monje" 5 => "F. Norman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eimc.2009.11.003" "Revista" => array:6 [ "tituloSerie" => "Enferm Infecc Microbiol Clin" "fecha" => "2010" "volumen" => "28" "paginaInicial" => "44" "paginaFinal" => "59" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20031280" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0110" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diplogonoporiasis presumably introduced into Spain: first confirmed case of human infection acquired outside the Far East" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Clavel" 1 => "M.D. Bargues" 2 => "F.J. Castillo" 3 => "M.D. Rubio" 4 => "S. Mas-Coma" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Trop Med Hyg" "fecha" => "1997" "volumen" => "57" "paginaInicial" => "317" "paginaFinal" => "320" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9311643" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/24443824/0000004000000009/v1_201711260719/S2444382417301542/v1_201711260719/en/main.assets" "Apartado" => array:4 [ "identificador" => "48446" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Scientific letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/24443824/0000004000000009/v1_201711260719/S2444382417301542/v1_201711260719/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2444382417301542?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 October | 41 | 4 | 45 |
| 2024 September | 94 | 6 | 100 |
| 2024 August | 84 | 3 | 87 |
| 2024 July | 74 | 4 | 78 |
| 2024 June | 50 | 5 | 55 |
| 2024 May | 68 | 9 | 77 |
| 2024 April | 60 | 2 | 62 |
| 2024 March | 68 | 9 | 77 |
| 2024 February | 70 | 2 | 72 |
| 2024 January | 68 | 1 | 69 |
| 2023 December | 63 | 3 | 66 |
| 2023 November | 89 | 1 | 90 |
| 2023 October | 113 | 5 | 118 |
| 2023 September | 40 | 3 | 43 |
| 2023 August | 51 | 0 | 51 |
| 2023 July | 84 | 1 | 85 |
| 2023 June | 79 | 0 | 79 |
| 2023 May | 121 | 0 | 121 |
| 2023 April | 97 | 0 | 97 |
| 2023 March | 84 | 5 | 89 |
| 2023 February | 58 | 1 | 59 |
| 2023 January | 65 | 5 | 70 |
| 2022 December | 61 | 5 | 66 |
| 2022 November | 62 | 6 | 68 |
| 2022 October | 55 | 9 | 64 |
| 2022 September | 58 | 14 | 72 |
| 2022 August | 58 | 5 | 63 |
| 2022 July | 49 | 9 | 58 |
| 2022 June | 40 | 8 | 48 |
| 2022 May | 46 | 8 | 54 |
| 2022 April | 84 | 8 | 92 |
| 2022 March | 87 | 9 | 96 |
| 2022 February | 92 | 8 | 100 |
| 2022 January | 117 | 10 | 127 |
| 2021 December | 84 | 8 | 92 |
| 2021 November | 64 | 12 | 76 |
| 2021 October | 62 | 9 | 71 |
| 2021 September | 89 | 11 | 100 |
| 2021 August | 61 | 9 | 70 |
| 2021 July | 22 | 6 | 28 |
| 2021 June | 21 | 9 | 30 |
| 2021 May | 47 | 9 | 56 |
| 2021 April | 79 | 10 | 89 |
| 2021 March | 57 | 7 | 64 |
| 2021 February | 42 | 16 | 58 |
| 2021 January | 36 | 11 | 47 |
| 2020 December | 43 | 12 | 55 |
| 2020 November | 31 | 6 | 37 |
| 2020 October | 32 | 5 | 37 |
| 2020 September | 35 | 10 | 45 |
| 2020 August | 21 | 10 | 31 |
| 2020 July | 22 | 12 | 34 |
| 2020 June | 19 | 8 | 27 |
| 2020 May | 29 | 8 | 37 |
| 2020 April | 11 | 1 | 12 |
| 2020 March | 21 | 6 | 27 |
| 2020 February | 22 | 2 | 24 |
| 2020 January | 10 | 0 | 10 |
| 2019 December | 13 | 7 | 20 |
| 2019 November | 9 | 9 | 18 |
| 2018 July | 0 | 0 | 0 |
| 2018 June | 1 | 0 | 1 |
Show all
