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Inicio Hipertensión y Riesgo Vascular Obesidad como factor de riesgo cardiovascular
Journal Information
Vol. 22. Issue 1.
Pages 32-36 (January 2005)
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Vol. 22. Issue 1.
Pages 32-36 (January 2005)
Obesidad como factor de riesgo cardiovascular
Obesity as cardiovascular risk factor
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A. Zugasti Murillo
Corresponding author
azugas@terra.es

Correspondencia: C./ San Cristóbal, 16, 2.o izq. 31015 Pamplona. Navarra.
, B. Moreno Esteban
Unidad de Obesidad. Hospital General Universitario Gregorio Marañón. Madrid. España
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La obesidad es una enfermedad metabólica crónica con riesgo cardiovascular asociado y una morbimortalidad aumentada. Actualmente el sobrepeso y la obesidad se consideran tan importantes como otros factores de riesgo clásico relacionados con la enfermedad coronaria. El tejido adiposo no sólo actúa como almacén de moléculas grasas, sino que sintetiza y libera a la sangre numerosas hormonas relacionadas con el metabolismo de principios inmediatos y la regulación de la ingesta. Asimismo, la obesidad se asocia a numerosos factores de riesgo cardiovasculares como dislipidemia, hipertensión, diabetes, marcadores inflamatorios y estado protrombótico. La pérdida de peso puede evitar la progresión de la placa de aterosclerosis y los eventos coronarios agudos en los sujetos obesos.

Palabras clave:
obesidad
síndrome metabólico
resistencia insulínica
enfermedad cardiovascular

Obesity is a chronic metabolic disease associated with cardiovascular risk and increased morbidity and mortality. Being overweighted and obese are now considered to be as important as other classic risk factors related to heart disease. Fatty tissue not only acts as stores of fat molecules but synthesizes and releases hormones to the blood which are related to the metabolism of basic food molecules and regulation of food intake. Likewise, obesity is associated with numerous cardiovascular risk factors such as dyslipidemia, hypertension, diabetes, inflammatory markers and prothrombotic state. Weight loss can prevent acute progression of atherosclerotic plaque and coronary events in obese subjects.

Key words:
obesity
metabolic syndrome
insulin resistance
cardiovascular disease

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