Anti-IL-6 receptor antibody treatment for severe COVID-19 and the potential implication of IL-6 gene polymorphisms in novel coronavirus pneumonia

Ulhaq, Zulvikar Syambani; Soraya, Gita Vita

doi:10.1016/j.medcle.2020.07.014

ISSN: 2387-0206

Launched in 1943, Medicina Clínica is a fortnightly journal aimed at the promotion of clinical research and practice among internal medicine and other specialists. The key characteristics of Medicina Clínica are the scientific and methodological rigor of its manuscripts, the topicality of its contents, and, especially, its practical focus with highly useful information for clinical practice. Medicina Clínica is predominantly interested in publishing original research manuscripts, which are rigorously selected according to their quality, originality, and interest, and also in continued medical education-oriented manuscripts, which are commissioned by the journal to relevant authors (Editorials, Reviews, and Diagnosis and Treatment). These manuscripts contain updated topics with a major clinical or conceptual relevance in modern medicine.
The journal adheres to the standards of academic research publications in all aspects including peer-review and ethical principles.
Medicina Clínica is included in the General and Internal Medicine category of Thomson Reuters.

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Vol. 155. Issue 12.

Pages 548-556 (December 2020)

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Vol. 155. Issue 12.

Pages 548-556 (December 2020)

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DOI: 10.1016/j.medcle.2020.07.014

Anti-IL-6 receptor antibody treatment for severe COVID-19 and the potential implication of IL-6 gene polymorphisms in novel coronavirus pneumonia

Tratamiento con anticuerpos anti-receptor de IL-6 para COVID-19 grave y la posible implicación de polimorfismos del gen IL-6 en la nueva neumonía por coronavirus

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Zulvikar Syambani Ulhaqa,1,

Corresponding author

zulhaq@kedokteran.uin-malang.ac.id

Corresponding author.

, Gita Vita Sorayab,1

a Department of Biochemistry, Faculty of Medicine and Health Sciences, Maulana Malik Ibrahim Islamic State University of Malang, Batu, East Java 65151, Indonesia

b Department of Biochemistry, Faculty of Medicine, Hasanuddin University, Makassar, South Sulawesi 90245, Indonesia

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Table 1. Systematic review of case report and case-series evaluating anti-IL-6R treatment in severe COVID-19.

Table 2. Characteristic of retrospective case-control and prospective cohort studies included in the analysis of anti-IL-6R treatment in severe COVID-19.