array:24 [ "pii" => "S2387020620301819" "issn" => "23870206" "doi" => "10.1016/j.medcle.2019.06.029" "estado" => "S300" "fechaPublicacion" => "2020-06-12" "aid" => "4986" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2019" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2020;154:472" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0025775319305408" "issn" => "00257753" "doi" => "10.1016/j.medcli.2019.06.032" "estado" => "S300" "fechaPublicacion" => "2020-06-12" "aid" => "4986" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2020;154:472" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4 "PDF" => 4 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Imagen médica</span>" "titulo" => "Deterioro cognitivo subagudo como comienzo de una angeítis primaria del sistema nervioso central" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "472" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Subacute cognitive impairment as clinical presentation of primary angiitis of the central nervous system" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 337 "Ancho" => 900 "Tamanyo" => 157087 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Lucas Barea-Moya, María Mateo-Casas, Héctor Aparicio-Collado, Ana Segura-Cerdá, Rodrigo Grande-González, María Elena Mengual-García, Rosa María Vilar-Ventura, Carlos Vilar-Fabra" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Lucas" "apellidos" => "Barea-Moya" ] 1 => array:2 [ "nombre" => "María" "apellidos" => "Mateo-Casas" ] 2 => array:2 [ "nombre" => "Héctor" "apellidos" => "Aparicio-Collado" ] 3 => array:2 [ "nombre" => "Ana" "apellidos" => "Segura-Cerdá" ] 4 => array:2 [ "nombre" => "Rodrigo" "apellidos" => "Grande-González" ] 5 => array:2 [ "nombre" => "María Elena" "apellidos" => "Mengual-García" ] 6 => array:2 [ "nombre" => "Rosa María" "apellidos" => "Vilar-Ventura" ] 7 => array:2 [ "nombre" => "Carlos" "apellidos" => "Vilar-Fabra" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2387020620301819" "doi" => "10.1016/j.medcle.2019.06.029" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620301819?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775319305408?idApp=UINPBA00004N" "url" => "/00257753/0000015400000011/v1_202005280632/S0025775319305408/v1_202005280632/es/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S2387020620301820" "issn" => "23870206" "doi" => "10.1016/j.medcle.2020.04.001" "estado" => "S300" "fechaPublicacion" => "2020-06-12" "aid" => "4985" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2020;154:473" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Syndrome of inappropriate antidiuretic hormone secretion in a patient with diffuse large B-cell lymphoma" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "473" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Síndrome de secreción inadecuada de hormona antidiurética en paciente con linfoma difuso de células grandes B" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 649 "Ancho" => 1255 "Tamanyo" => 89939 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Begoña Navarro-Almenzar, Valentin Cabañas Perianes" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Begoña" "apellidos" => "Navarro-Almenzar" ] 1 => array:2 [ "nombre" => "Valentin" "apellidos" => "Cabañas Perianes" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775319305391" "doi" => "10.1016/j.medcli.2019.06.031" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775319305391?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620301820?idApp=UINPBA00004N" "url" => "/23870206/0000015400000011/v1_202006060744/S2387020620301820/v1_202006060744/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2387020620301807" "issn" => "23870206" "doi" => "10.1016/j.medcle.2019.04.048" "estado" => "S300" "fechaPublicacion" => "2020-06-12" "aid" => "4899" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Med Clin. 2020;154:470-1" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Treatment adapted to pregnancy in a patient with Burkitt lymphoma" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "470" "paginaFinal" => "471" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tratamiento adaptado a la gestación en una paciente con linfoma de Burkitt" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Martina Comes, Montserrat Batlle, Josep-Maria Ribera" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Martina" "apellidos" => "Comes" ] 1 => array:2 [ "nombre" => "Montserrat" "apellidos" => "Batlle" ] 2 => array:2 [ "nombre" => "Josep-Maria" "apellidos" => "Ribera" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775319304178" "doi" => "10.1016/j.medcli.2019.04.038" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775319304178?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620301807?idApp=UINPBA00004N" "url" => "/23870206/0000015400000011/v1_202006060744/S2387020620301807/v1_202006060744/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Subacute cognitive impairment as clinical presentation of primary angiitis of the central nervous system" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "472" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Lucas Barea-Moya, María Mateo-Casas, Héctor Aparicio-Collado, Ana Segura-Cerdá, Rodrigo Grande-González, María Elena Mengual-García, Rosa María Vilar-Ventura, Carlos Vilar-Fabra" "autores" => array:8 [ 0 => array:4 [ "nombre" => "Lucas" "apellidos" => "Barea-Moya" "email" => array:1 [ 0 => "barea.moya@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "María" "apellidos" => "Mateo-Casas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Héctor" "apellidos" => "Aparicio-Collado" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "Ana" "apellidos" => "Segura-Cerdá" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "Rodrigo" "apellidos" => "Grande-González" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 5 => array:3 [ "nombre" => "María Elena" "apellidos" => "Mengual-García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 6 => array:3 [ "nombre" => "Rosa María" "apellidos" => "Vilar-Ventura" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 7 => array:3 [ "nombre" => "Carlos" "apellidos" => "Vilar-Fabra" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neurología, Hospital General Universitario de Castellón, Castellón de la Plana, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital General Universitario de Castellón, Castellón de la Plana, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Deterioro cognitivo subagudo como comienzo de una angeítis primaria del sistema nervioso central" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 923 "Ancho" => 900 "Tamanyo" => 128719 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">An 81-year-old man was evaluated in the neurology department of our center for a 4-week history of cognitive impairment and generalized weakness. The patient did not associate headache, other neurological deficits, or systemic involvement.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A magnetic resonance imaging (MRI) study was performed, which showed a lesion in the corpus callosum (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A) that decreased in size during his 6-month follow-up (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). However, 18 months later, new lesions appeared in the left frontal lobe and a large lesion in the right temporal lobe with a mass effect and contrast uptake (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B and <span class="elsevierStyleSmallCaps">C</span>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Laboratory tests including systematic analysis, serologies and angiotensin converting enzyme levels were normal. An electroencephalogram was performed, which was normal. Given the nonspecific clinical presentation, the progression and the neuroimaging findings, an inflammatory process was suspected, so a biopsy of the lesion was scheduled.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Brain biopsy (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>) showed chronic inflammatory involvement of the intracerebral and leptomeningeal blood vessels (black arrows) in and around the blood vessel walls (white arrows) confirming the diagnosis of primary angiitis of the central nervous system.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0025" class="elsevierStylePara elsevierViewall">No funding has been received for the completion of this article.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Barea-Moya L, Mateo-Casas M, Aparicio-Collado H, Segura-Cerdá A, Grande-González R, Mengual-García ME, et al. Deterioro cognitivo subagudo como comienzo de una angeítis primaria del sistema nervioso central. Med Clin (Barc). 2020;154:472.</p>" ] ] "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 923 "Ancho" => 900 "Tamanyo" => 128719 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 374 "Ancho" => 1000 "Tamanyo" => 175487 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000015400000011/v1_202006060744/S2387020620301819/v1_202006060744/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000015400000011/v1_202006060744/S2387020620301819/v1_202006060744/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620301819?idApp=UINPBA00004N" ]
Journal Information
Vol. 154. Issue 11.
Pages 472 (June 2020)
Share
Download PDF
More article options
Vol. 154. Issue 11.
Pages 472 (June 2020)
Image in medicine
Subacute cognitive impairment as clinical presentation of primary angiitis of the central nervous system
Deterioro cognitivo subagudo como comienzo de una angeítis primaria del sistema nervioso central
Visits
3
This item has received
Article information
These are the options to access the full texts of the publication Medicina Clínica (English Edition)
Subscriber
Subscribe
Purchase
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail