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Inicio Medicina Clínica (English Edition) Squamous cell carcinoma in solid organ transplant recipients: Review of the lite...
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Available online 1 November 2024
Squamous cell carcinoma in solid organ transplant recipients: Review of the literature
Carcinoma escamoso cutáneo en pacientes trasplantados de órgano sólido: revisión de la literatura
Inés Oteiza Rius, Ana Morelló Vicente
Corresponding author
amorellovic@unav.es

Corresponding author.
, Leyre Aguado Gil
Departamento de Dermatología, Clínica Universidad de Navarra, Pamplona, Spain
Received 16 January 2024. Accepted 02 May 2024
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Abstract

Solid organ transplant recipients (SOTRs) exhibit an elevated incidence and aggressiveness of squamous cell carcinomas (SCCs) due to their immunosuppression. These tumors are associated with a heightened risk of metastasis and increased mortality. Therefore, an appropriate management of these patients is essential to improve their prognosis. Given the scarcity of studies on non-melanoma skin cancers (NMSCs) in SOTRs, this article aims to summarize and analyze the evidence gathered to date regarding therapeutic approaches, personalized monitoring, and prevention strategies for SCCs in these patients. Additionally, recent advancements in understanding SCCs within this patient group are also documented.

Keywords:
Squamous cell carcinoma
Solid organ transplant recipients
Immunosuppression
Resumen

Los pacientes trasplantados de órgano sólido (PTOS) presentan una mayor incidencia y agresividad de carcinomas escamosos (CECs) debido a su inmunosupresión. Estos tumores se asocian a un mayor riesgo de metástasis y a un aumento de la mortalidad. Por lo tanto, un adecuado manejo de estos pacientes resulta esencial para favorecer su pronóstico. Dada la escasez de estudios sobre los cánceres cutáneos no melanoma (CCNM) en PTOS, este artículo pretende resumir y analizar las evidencias recogidas hasta la fecha sobre el enfoque terapéutico, seguimiento personalizado y estrategias de prevención en estos pacientes en relación al CEC. Asimismo, se recogen las novedades sobre el CEC descritas en este grupo de pacientes durante los últimos años.

Palabras clave:
Carcinoma escamoso cutáneo
Trasplantados de órgano sólido
Inmunosupresión

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