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"documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2017;148:195" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Erythema multiforme minor. From mouth to skin" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "195" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Eritema multiforme minor. De la boca a la piel" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 600 "Ancho" => 450 "Tamanyo" => 41794 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Miguel Alberto Rodríguez Pérez, José Francisco Delgado Álvarez" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Miguel Alberto" "apellidos" => "Rodríguez Pérez" ] 1 => array:2 [ "nombre" => "José Francisco" "apellidos" => "Delgado Álvarez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775316301567" "doi" => "10.1016/j.medcli.2016.05.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775316301567?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020617301213?idApp=UINPBA00004N" "url" => "/23870206/0000014800000004/v1_201703290102/S2387020617301213/v1_201703290102/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Cutaneous collagenous vasculopathy: A rare cause of generalized cutaneous telangiectasia" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "e23" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Igor Vázquez-Osorio, Pablo Gonzalvo-Rodríguez, Eloy Rodríguez-Díaz" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Igor" "apellidos" => "Vázquez-Osorio" "email" => array:1 [ 0 => "rogivaos@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Pablo" "apellidos" => "Gonzalvo-Rodríguez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Eloy" "apellidos" => "Rodríguez-Díaz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario de Cabueñes, Gijón, Asturias, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario de Cabueñes, Gijón, Asturias, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Vasculopatía colágena cutánea: una causa infrecuente de telangiectasias generalizadas" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 700 "Ancho" => 1018 "Tamanyo" => 136287 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">88-Year-old woman with hypertension and osteoporosis, who consulted for asymptomatic lesions on the limbs which began to appear 15 years earlier. She reported no family history of similar lesions or personal or family history of bleeding of mucous membranes. Multiple telangiectasias which turned white with finger pressure were observed on examination, distributed bilaterally and symmetrically in the four limbs (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Skin biopsy showed multiple dilated vessels in the superficial dermis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A), with walls remarkably thickened due to deposition of hyaline material (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>B), which was stained with PAS-diastase (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>C) and showed positive immunostaining for collagen IV (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>D). Laboratory results showed no abnormalities.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Cutaneous collagenous vasculopathy is an acquired and idiopathic microangiopathy affecting individuals in the fourth or fifth decade of life. There is no association with systemic disease or specific laboratory findings. Although its definitive diagnosis is histological, an adequate case history is essential to rule out other entities that present with widespread telangiectasia and systemic involvement, such as generalized essential telangiectasia, hereditary hemorrhagic telangiectasia, connective tissue diseases, mastocytosis, amyloidosis, lymphoma or liver disease.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Telangiectasia distribution, age at onset and absence of symptoms and family history are key data.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Vázquez-Osorio I, Gonzalvo-Rodríguez P, Rodríguez-Díaz E. Vasculopatía colágena cutánea: una causa infrecuente de telangiectasias generalizadas. 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