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Inicio Psiquiatría Biológica Encefalitis por anticuerpos contra el receptor NMDA: a propósito de un caso
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Vol. 28. Issue 2.
(May - August 2021)
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Vol. 28. Issue 2.
(May - August 2021)
Caso clínico
Encefalitis por anticuerpos contra el receptor NMDA: a propósito de un caso
Anti-NMDAR encephalitis: Case report
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11
Sergio Ciria Villar
Corresponding author
sergicivi@gmail.com

Autor para correspondencia.
, Camino Pérez Pemán, Pablo Ortega López-Alvarado
Servicio de Psiquiatría, Hospital Universitario Miguel Servet, Zaragoza, España
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Objetivo

El objetivo de este artículo es destacar la importancia de la realización de un estudio orgánico completo ante un primer episodio psicótico, a través de un caso clínico con diagnóstico de encefalitis autoinmune por anticuerpos anti-NMDA.

Caso clínico

Se presenta el caso clínico de un varón de 35 años, sin antecedentes psiquiátricos de interés, que comienza con clínica psicótica aguda en forma de alucinaciones y desorganización conductual. El paciente se encontraba pendiente de estudio de un cuadro sincopal sufrido el mes previo al comienzo, con traumatismo craneoencefálico secundario. Finalmente, el cuadro se filió como encefalitis por anticuerpos anti-NMDA, respondiendo favorablemente al tratamiento inmunosupresor.

Resultados

El abordaje desde el punto de vista neurológico ha sido fundamental para lograr la mejoría del cuadro psicótico agudo.

Conclusiones

Es necesaria una colaboración estrecha entre los servicios de Psiquiatría y Neurología ante un primer episodio psicótico.

Palabras clave:
Encefalitis
Psicosis
Abstract
Objective

The aim of this article is to outline the importance of carrying out a complete organic study when encountering a first psychotic episode by means of a case report showing a diagnosis of anti-NMDA receptor encephalitis.

Case report

A 35 year-old male, presented without a significant psychiatric history, starts to suffer from severe psychotic symptoms such as hallucinations and behavioural problems. The patient was on the lookout for a study of a syncope with secondary traumatic brain injury experienced one month prior to the beginning of the symptoms. Finally, the patient was diagnosed with anti-NMDAR encephalitis, showing symptom improvement with this immunosuppressive treatment.

Results

The approach from a neurological perspective has been of outmost importance in order to improve the aforementioned severe psychotic symptoms.

Conclusions

A close cooperation between the Psychiatry and Neurology departments is needed when encountering a first psychotic episode.

Keywords:
Encephalitis
Psychosis

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