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Inicio Radiología Tumor estromal gastrointestinal: diagnóstico y pronóstico*
Journal Information
Vol. 45. Issue 6.
Pages 269-272 (January 2003)
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Vol. 45. Issue 6.
Pages 269-272 (January 2003)
Tumor estromal gastrointestinal: diagnóstico y pronóstico*
Gastrointestinal stromal tumor: diagnosis and prognosis
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M. Teresa Martína,
Corresponding author
mtmartin@fhalcorcon.es

M. TERESA MARTÍN FERNÁNDEZ-GALLARDO. C/ Orense, 37, 5.º-C. 28020 Madrid. España.
, Pilar Olmedillaa, Saturnino Gonzáleza, Jose M. Olivera
a Fundación Hospital Alcorcón. Alcorcón. Madrid. España.
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Los tumores estromales gastrointestinales (GIST) son tumores me-senquimatosos derivados de una célula precursora. Tiene capacidad de diferenciación miogénica o neurogénica y se caracterizan por la expre-sión de proteína KIT (factor de crecimiento de la tirosincinasa).

Clinicamente presentan un comportamiento biológico variable. Pre-sentamos ocho casos de GIST, describiendo su presentación radiológi-ca en tomografía computarizada (TC) así como los criterios de benig-nidad y malignidad más aceptados en la bibliografía.

Además, presentamos la respuesta de uno de ellos con metástasis al diagnóstico, tras tratamiento con inhibidor de la tirosincinasa.

Palabras clave:
Tumor estromal gastrointestinal (GIST)
Tomografía computarizada (TC)
Pronóstico

Gastrointestinal stromal tumors (GIST) are mesenquimal tumors derived from cell precursors. They have the capacity for myogenic and neurogenic differentiation and are characterized by expression of KIT protein (tyrosine kinase growth factor). Clinically, they exhibit variou biological behaviors. We present 8 cases of GIST, describing both their radiological manifestation through computerized tomography (CT) and most accepted criteria for benignity and malignancy. We also describe the response of one metastatically diagnosed tumor to tyrosine kinase inhibitor.

Key words:
Gastrointestinal stromal tumor (GIST)
CT
Prognosis

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