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Vol. 66. Issue S2.
Suplement “Update and good practice in the contrast media uses”
Pages S132-S141 (October 2024)
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Vol. 66. Issue S2.
Suplement “Update and good practice in the contrast media uses”
Pages S132-S141 (October 2024)
Update and good practice in the contrast media uses
Future challenges of contrast media in radiology
Los retos futuros de los medios de contraste en radiología
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17
E. Alvarez-Hornia Péreza,b,
Corresponding author
edu.alvarezhornia@deusto.es

Corresponding author.
, C. Carnellic, P.A. Gutierrezd, R. González Sáncheze, J. Mesa Quesadaf
a Clínica IMQ Zorrotzaurre, Bilbao, Spain
b Universidad de Deusto, Bilbao, Spain
c Unidad Académica de Imagenología Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay
d CH Dunkerque, Department of Radiology, Dunkirk, France
e Hospital Universitario de Basurto, Bilbao, Spain
f Hospital Universitario Reina Sofía, Córdoba, Spain
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Table 1. Development pathways for new contrast media in the form of new molecules or new indications.
Special issue
This article is part of special issue:
Vol. 66. Issue S2

Suplement “Update and good practice in the contrast media uses”

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Abstract

Contrast media (CM) were first used soon after the discovery of X-rays in 1895. Ever since, continuous technological development and pharmaceutical research has led to tremendous progress in radiology, more available techniques and contrast media, and expanded knowledge around their indications.

A greater prevalence of chronic diseases, population ageing, and the rise in diagnosis and survival times among cancer patients have resulted in a growing demand for diagnostic imaging and an increased consumption of CM.

This article presents the main lines of research in CM development which seek to minimise toxicity and maximise efficacy, opening up new diagnostic and therapeutic possibilities through new molecules or nanomedicine. The sector, which is continuously evolving, faces challenges such as shortages and the need for more equitable and sustainable practices.

Keywords:
Contrast media
Image enhancement
Diagnostic imaging
Radiology
Computed tomography
Iodine
Magnetic resonance imaging
Gadolinium
Ultrasonography
Mammography
Resumen

La historia de los medios de contraste (MC) comienza poco después del descubrimiento de los rayos X en 1895. Desde esos pasos iniciales, un proceso de desarrollo tecnológico continuo y de investigación fármaco-química, están conduciendo a una enorme evolución de la radiología, ampliando las técnicas disponibles, los medios de contraste y sus indicaciones.

La mayor prevalencia de enfermedades crónicas, el envejecimiento poblacional y el aumento de diagnóstico y supervivencia en los pacientes oncológicos han supuesto una demanda creciente de pruebas radiológicas y simultáneamente, un continuo incremento del consumo de MC.

En este trabajo presentamos las principales líneas de investigación en MC que buscan minimizar la toxicidad y maximizar la eficacia, abriendo nuevas posibilidades diagnósticas y terapéuticas a través de nuevas moléculas o la nanomedicina. Al mismo tiempo el sector enfrenta desafíos como el desabastecimiento y la necesidad de prácticas más igualitarias y sostenibles reflejando un campo en constante evolución.

Palabras clave:
Medios de contraste
Realce de la imagen
Diagnóstico por imágenes
Radiología
Tomografía computarizada
Yodo
Resonancia magnética
Gadolinio
Ecografía
Mamografía

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