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Inicio Radiología (English Edition) Ways of analysing extracellular gadolinium enhancement
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Vol. 66. Issue S2.
Suplement “Update and good practice in the contrast media uses”
Pages S65-S74 (October 2024)
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Vol. 66. Issue S2.
Suplement “Update and good practice in the contrast media uses”
Pages S65-S74 (October 2024)
Update and good practice in the contrast media uses
Ways of analysing extracellular gadolinium enhancement
Tipos de análisis de la captación de Gadolinio extracelular
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3
C. Casillas Meléndez
Servicio de Diagnóstico por Imagen, Consorcio Hospitalario Provincial de Castellón, Castellón, Spain
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Table 1. Multiphase dynamic sequence. Temporal resolution depending on the organ under study.
Table 2. Quantitative analysis with MRI perfusion studies. Biological properties, parameters and correlation.
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Special issue
This article is part of special issue:
Vol. 66. Issue S2

Suplement “Update and good practice in the contrast media uses”

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Abstract

The use of extracellular gadolinium-based contrast agents provides valuable information in magnetic resonance studies, thus increasing diagnostic confidence. These contrast agents make it easier to detect and define injuries, and narrow down the differential diagnosis. They are indicated for several different reasons, both for diagnostic purposes and for evaluating the response to treatment. Morphological analysis can assess the type of uptake, the qualitative and semiquantitative study of the signal intensity vs time curves in multiphase sequences, and the quantitative analysis of the uptake with T1 or T2* perfusion studies associated with pharmacokinetic models.

Multiphase dynamic studies with 3D sequences contain valuable information that is not exploited by a simple visual analysis of 2D images. To take advantage of this information and the imaging biomarkers provided, computational analysis should be used. To this end, the future role of artificial intelligence is increasingly evident.

Keywords:
Image interpretation
Multiparametric magnetic resonance imaging
Contrast media
Perfusion imaging
Radiomics
Artificial intelligence
Resumen

El uso de agentes de contraste extracelular basados en Gadolinio proporciona información valiosa en los estudios de RM, aumentando la confianza diagnóstica. Amplifican la capacidad para detectar y delimitar lesiones, así como para acotar el diagnóstico diferencial. Sus indicaciones son múltiples, tanto para el diagnóstico como para la evaluación de la respuesta al tratamiento. Su estimación puede realizarse con el análisis morfológico del tipo de captación, el estudio cualitativo y semicuantitativo de las curvas de intensidad de señal vs tiempo en secuencias multifase, o analizando cuantitativamente la captación con estudios de perfusión T1 o T2* asociados a modelos farmacocinéticos.

Los estudios dinámicos multifase con secuencias 3D contienen información valiosa que no se utiliza con el simple análisis visual de las imágenes 2D. Para aprovechar esta información subyacente, que proporciona biomarcadores de imagen, es necesario el análisis computacional. En este aspecto, el futuro papel de la Inteligencia Artificial se hace cada día más evidente.

Palabras clave:
Interpretación de imagen
Resonancia magnética muliparamétrica
Medio de contraste
Imagen de perfusión
Radiómica
Inteligencia artificial

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