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array:24 [ "pii" => "S2173510721001166" "issn" => "21735107" "doi" => "10.1016/j.rxeng.2021.10.004" "estado" => "S300" "fechaPublicacion" => "2021-11-01" "aid" => "1313" "copyright" => "SERAM" "copyrightAnyo" => "2021" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Radiologia. 2021;63:505-11" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S003383382100120X" "issn" => "00338338" "doi" => "10.1016/j.rx.2021.07.001" "estado" => "S300" "fechaPublicacion" => "2021-11-01" "aid" => "1313" "copyright" => "SERAM" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Radiologia. 2021;63:505-11" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Actualización</span>" "titulo" => "Repaso anatómico de la arteria cerebral media en la era de la trombectomía: una herramienta radiológica basada en la angio-TC y la TC perfusión" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "505" "paginaFinal" => "511" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "A review of the anatomy of the middle cerebral artery for the era of thrombectomy: a radiologic tool based on CT angiography and perfusion CT" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2324 "Ancho" => 1675 "Tamanyo" => 173946 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Esquema de la distribución espacial/anatómica de los segmentos de la arteria cerebral media a lo largo de su recorrido intracraneal. Segmentos M1 (en rojo), M2 (en azul), M3 (en verde) y M4 (en amarillo).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Medrano-Martorell, M. Pumar-Pérez, S. González-Ortiz, J. Capellades-Font" "autores" => array:4 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Medrano-Martorell" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Pumar-Pérez" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "González-Ortiz" ] 3 => array:2 [ "nombre" => "J." 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A systematic review" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "512" "paginaFinal" => "518" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hallazgos ecográficos en el tejido tímico ectópico intratiroideo en niños y adolescentes. Una revisión sistemática" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2396 "Ancho" => 2174 "Tamanyo" => 269478 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The flow diagram for the systematic selection of the literature and the inclusion of articles in the analysis.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Gómez-Herrera, M.A. Melo-Uribe, R. Parra-Medina" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Gómez-Herrera" ] 1 => array:2 [ "nombre" => "M.A." "apellidos" => "Melo-Uribe" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Parra-Medina" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0033833821001442" "doi" => "10.1016/j.rx.2021.06.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0033833821001442?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217351072100104X?idApp=UINPBA00004N" "url" => "/21735107/0000006300000006/v1_202111180655/S217351072100104X/v1_202111180655/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2173510721000896" "issn" => "21735107" "doi" => "10.1016/j.rxeng.2021.04.004" "estado" => "S300" "fechaPublicacion" => "2021-11-01" "aid" => "1302" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Radiologia. 2021;63:495-504" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Update in Radiology</span>" "titulo" => "CT presentations of adult and pediatric SARS-CoV-2 patients: A review of early COVID-19 data" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "495" "paginaFinal" => "504" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Comparación de los hallazgos en la tomografía computarizada de pacientes adultos y pediátricos con COVID-19" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 515 "Ancho" => 1500 "Tamanyo" => 119771 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The initial CT (A) obtained shows multiple ground-glass opacities in the posterior right upper lobe and left superior lobe. The follow-up CT scan (B) 3 days later shows that the GGO expanded in the posterior right upper lobe and left superior lobe. Reprinted with permission from Ref.<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">29</span></a> Lei J, Li J, Li X, Qi X. CT Imaging of the 2019 Novel Coronavirus (2019-nCoV) Pneumonia. <span class="elsevierStyleItalic">Radiology</span>. 2020;295(1):18.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.V. Waller, K.K. Lin, M.J. Diaz, T. Miao, A. Amireh, Ch. Agyemang, R.E. Carter, S. Bae, T. Henry" "autores" => array:9 [ 0 => array:2 [ "nombre" => "J.V." "apellidos" => "Waller" ] 1 => array:2 [ "nombre" => "K.K." "apellidos" => "Lin" ] 2 => array:2 [ "nombre" => "M.J." "apellidos" => "Diaz" ] 3 => array:2 [ "nombre" => "T." "apellidos" => "Miao" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Amireh" ] 5 => array:2 [ "nombre" => "Ch." "apellidos" => "Agyemang" ] 6 => array:2 [ "nombre" => "R.E." "apellidos" => "Carter" ] 7 => array:2 [ "nombre" => "S." "apellidos" => "Bae" ] 8 => array:2 [ "nombre" => "T." "apellidos" => "Henry" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S003383382100093X" "doi" => "10.1016/j.rx.2021.04.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S003383382100093X?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173510721000896?idApp=UINPBA00004N" "url" => "/21735107/0000006300000006/v1_202111180655/S2173510721000896/v1_202111180655/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Update in Radiology</span>" "titulo" => "A review of the anatomy of the middle cerebral artery for the era of thrombectomy: A radiologic tool based on CT angiography and perfusion CT" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "505" "paginaFinal" => "511" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "S. Medrano-Martorell, M. Pumar-Pérez, S. González-Ortiz, J. Capellades-Font" "autores" => array:4 [ 0 => array:4 [ "nombre" => "S." "apellidos" => "Medrano-Martorell" "email" => array:1 [ 0 => "Santimedra@gmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Pumar-Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "S." "apellidos" => "González-Ortiz" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Capellades-Font" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Radiodiagnóstico, Hospital del Mar, Barcelona, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Radiodiagnóstico, Hospital Clinic, Barcelona, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Repaso anatómico de la arteria cerebral media en la era de la trombectomía: una herramienta radiológica basada en la angio-TC y la TC perfusión" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0030" "etiqueta" => "Figure 6" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr6.jpeg" "Alto" => 290 "Ancho" => 1255 "Tamanyo" => 43472 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0060" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Examples of bifurcation of both MCAs on CT angiography (5.1), trifurcation of the right MCA on CT angiography (5.2) and monofurcation of the left MCA on magnetic resonance (MR) angiography (5.3).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction: why is a review of the middle cerebral artery important?</span><p id="par0005" class="elsevierStylePara elsevierViewall">The middle cerebral artery (MCA) is, along with the anterior cerebral artery, one of the terminal branches of the internal carotid artery. It is responsible for supplying blood to large parts of the cerebral hemispheres. Hence, it is the vessel seen to be affected in the majority of cerebral ischaemic events,<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> which account for a great many radiological emergencies in our setting. In recent years, stroke management has been undergoing changes. The latest American Heart Association/American Stroke Association guidelines<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> feature updates to the prior guidelines on endovascular treatment in stroke, including the use of mechanical thrombectomy up to the first 24<span class="elsevierStyleHsp" style=""></span>h from the onset of symptoms in certain patients (those with large-vessel occlusions, mismatches on imaging tests [perfusion/diffusion] and certain clinical characteristics),<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4</span></a> and the use of endovascular techniques in occlusions up to the M3 segment of the MCA in particular patients.</p><p id="par0010" class="elsevierStylePara elsevierViewall">All this requires radiologists to have clear and accurate knowledge of vascular anatomy, so that in an emergency situation, faced with the diagnosis of a cerebral ischaemic event, they can quickly and correctly determine the site of occlusion in the vascular tree, where a mechanical thrombectomy will likely be performed right away. With this, radiologists can help speed along the diagnosis and treatment pathway and optimise the patient's prognosis. Thus, in addition to a review of the anatomy of the MCA with its possible anatomical variants and abnormalities, we present a radiological tool based on correlating perfusion and computed tomography (CT) angiography to facilitate determination of the location of obstruction in the affected branch in the diagnosis of a cerebral ischaemic event.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">MCA: segments</span><p id="par0015" class="elsevierStylePara elsevierViewall">Classic anatomical terminology establishes two MCA segments (M1 and M2) delimited by the bifurcation of the main trunk.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> In practice, however, for the surgical and radiological approach, four segments are distinguished (M1, M2, M3 and M4), described in the early 1980s by Gibo et al.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> and determined by the spatial distribution of the main trunk and successive branches (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>):<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">•</span><p id="par0020" class="elsevierStylePara elsevierViewall">M1: horizontal or sphenoidal segment. This originates at the bifurcation of the internal carotid artery and runs laterally on an axial plane, under the anterior perforated substance and parallel to the sphenoid wing, towards the Sylvian fissure. Its trajectory it can be divided into two or more trunks, such that there are two parts to the M1: the pre-bifurcation M1 segment and the post-bifurcation M1 segment (made up of the horizontal segments of each of the two or more corresponding trunks in each case). When the post-bifurcation segment trunks reach the limen insulae, they make a 90-degree turn known as the genu, terminating the M1 segment (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>.1).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">•</span><p id="par0025" class="elsevierStylePara elsevierViewall">M2: insular segment. This originates at the genu of the main trunks of the MCA and is comprised of these and their successive branches which circulate on the insulae, along the Sylvian fissure, on a vertical plane towards the most distal part of the insular circular sulcus. Here, they make another, sharper turn, forking to surround the opercula, where the M3 segment begins (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>.2).</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">•</span><p id="par0030" class="elsevierStylePara elsevierViewall">M3: opercular segments: from the most distal part of the circular sulcus, the branches run along the frontoparietal and temporal opercula towards the most lateral/superficial edge of the Sylvian fissure, where the M4 segments begin (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>.3).</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">•</span><p id="par0035" class="elsevierStylePara elsevierViewall">M4: cortical segments. From the lateral/superficial edge of the Sylvian fissure, the branches turn again, moving away from the edge and running in a superior or inferior direction on the cortical surface until terminating; these constitute the M4 segments (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>.4).</p></li></ul></p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">MCA: branches</span><p id="par0040" class="elsevierStylePara elsevierViewall">The MCA has two groups of branches: the perforating or lenticulostriate arteries and the cortical arteries.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">The perforating arteries are very low-calibre vessels that emerge in variable numbers, between eight and 20; most of them run along the M1 segment of the MCA and some of them also run from the anterior cerebral artery. Their limited calibre makes it difficult to fully identify them on angiography. These branches run superiorly through the anterior perforated substance to supply blood to the basal ganglia and deep structures of the brain. They are divided into a medial group and a lateral group, depending on whether they form before or after the division of the main trunk of the MCA. The medial group primarily supply the lentiform nucleus, part of the caudate nucleus and internal capsule; the lateral group ascend in a more superior direction to supply the external capsule and the caudate nucleus.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The cortical arteries are the branches that emerge along the MCA to supply the different cortical regions with blood. These are vessels of a considerably larger calibre, allowing them to be properly independently assessed using regular angiographic imaging techniques. The number of these branches also varies, and their pattern of emergence from the MCA is variable too, giving rise to wide anatomical variation. It is normal to have 10–12 cortical branches. The most common are the following: orbitofrontal, prefrontal, precentral, central, anterior parietal, posterior parietal, angular, temporopolar, anterior temporal, medial temporal, posterior temporal and temporo-occipital<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Anatomical variability of the middle cerebral artery</span><p id="par0055" class="elsevierStylePara elsevierViewall">The variability of the branching patterns is determined by three main factors: the presence of early branches, the division of the main trunk of the MCA and the dominance of the trunks<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> (<a class="elsevierStyleCrossRef" href="#fig0020">Fig. 4</a>).</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Early branches</span><p id="par0060" class="elsevierStylePara elsevierViewall">The majority of the cortical branches emerge from the MCA once their main trunk has divided, along those divisions or from other cortical branches. However, it is also possible for cortical branches to form prior to that division, emerging from the pre-bifurcation M1 segment; these are so-called early branches. These early branches may be temporal or frontal, with the temporopolar, anterior temporal or orbitofrontal arteries appearing as such. The most typical variant is the presence of one of these early branches, generally an early temporal branch.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> The next most typical variants are, in order of frequency: having two early branches; then having none; then, finally and less commonly, having three of these early branches<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> (<a class="elsevierStyleCrossRef" href="#fig0025">Fig. 5</a>).</p><elsevierMultimedia ident="fig0025"></elsevierMultimedia></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Division of the main trunk</span><p id="par0065" class="elsevierStylePara elsevierViewall">The main trunk of the MCA is divided into smaller trunks, generally along its M1 segment. The location of this division gives rise to variants. An early division corresponds to one that occurs very close to the formation of the MCA, with a very short pre-bifurcation segment (generally, less than 5<span class="elsevierStyleHsp" style=""></span>mm). A late division corresponds to a division seen to be proximal to the M2 segment.</p><p id="par0070" class="elsevierStylePara elsevierViewall">Division itself may vary as well. Most commonly, the main trunk divides into two trunks—that is to say, it bifurcates (in around 70% of cases) to form an anterosuperior trunk and a posteroinferior trunk.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">11,12</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">The next most common case would be trifurcation (in approximately 20% of cases), with the formation of a superior trunk, an intermediate trunk and an inferior trunk.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">11,12</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">The medical literature also features reports of less common possibilities, such as division into multiple trunks or even no divisions at all, with a single MCA trunk (each in less than 10% of cases)<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">12,13</span></a> (<a class="elsevierStyleCrossRef" href="#fig0030">Fig. 6</a>).</p><elsevierMultimedia ident="fig0030"></elsevierMultimedia></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Dominance of the divisions</span><p id="par0085" class="elsevierStylePara elsevierViewall">The dominance of a division is determined by its supplying blood to a larger region of the brain, which in turn is determined by its having a larger number of cortical branches emerging from it. Amounting to the same, some cortical branches form in one division or another depending on dominance.</p><p id="par0090" class="elsevierStylePara elsevierViewall">In the most typical case, bifurcation, the temporal branches form in the inferior division and the frontal branches form in the superior division. The parietal branches, for their part, may emerge from the superior trunk, the inferior trunk or some combination of both; this is determined by dominance of the anterosuperior division in the first case, dominance of the posteroinferior division in the second or no dominance in the third.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">In the case of trifurcation, in general, the temporal branches form from the inferior division, the parietal branches from the middle division and the frontal branches from the superior division. If any division shows itself to be dominant, this means that from it will emerge in addition a branch of an adjacent region that does not form in its corresponding division<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> (<a class="elsevierStyleCrossRefs" href="#fig0035">Figs. 7 and 8</a>).</p><elsevierMultimedia ident="fig0035"></elsevierMultimedia><elsevierMultimedia ident="fig0040"></elsevierMultimedia></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Abnormalities of the middle cerebral artery</span><p id="par0100" class="elsevierStylePara elsevierViewall">Abnormalities of the MCA are less common than abnormalities in other large intracranial arteries. They are due to abnormal fusion of primitive vascular networks. The following are considered as such: an accessory MCA, MCA duplication and, much less commonly, a duplicated MCA origin and MCA fenestration.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a></p><p id="par0105" class="elsevierStylePara elsevierViewall">An accessory MCA refers to the formation of an additional trunk parallel to the main MCA with an origin distal to it, from the anterior cerebral artery. It supplies blood to the anterior portion of the frontal lobe. MCA duplication corresponds to the formation of a trunk in addition to the main MCA but proximal to it, with both emerging from the internal carotid artery. It supplies blood to the anterior portion of the temporal lobe.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">A duplicated MCA origin is considered to be present when the proximal portion of an accessory MCA or a duplicated MCA persists and fuses distally with the main MCA. MCA fenestration is the name given to a fusion defect in the main trunk of the MCA after its origin, such that it emerges as a single trunk, branches and then re-fuses.<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a></p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Anatomical/radiological tool based on CT angiography and CT perfusion</span><p id="par0115" class="elsevierStylePara elsevierViewall">In clinical practice, CT perfusion can be leveraged to quickly locate the affected branch in a cerebral infarction if it is not possible to locate it on CT angiography.<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> This technique identifies the areas of the parenchyma that have been affected in an ischaemic event. Thus, if practitioners know the anatomy of the MCA with its branches and the corresponding regions to which they supply blood, by observing the ischaemic parenchyma on CT perfusion of a particular case, they will be able to sense which branch or branches have been affected. If they know the anatomical variants of the MCA, they can extrapolate the possible points of obstruction amongst the different MCA vascular tree possibilities and confirm which will be obstructed in that case on CT angiography.<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> The associated figures show real-world applied cases (<a class="elsevierStyleCrossRefs" href="#fig0045">Figs. 9 and 10</a>).</p><elsevierMultimedia ident="fig0045"></elsevierMultimedia><elsevierMultimedia ident="fig0050"></elsevierMultimedia><p id="par0120" class="elsevierStylePara elsevierViewall">To conclude, we would like to note that endovascular treatment of ischaemic stroke is becoming possible in more and more distal branches. This means that radiologists in emergency settings must possess detailed knowledge of cerebral vascular anatomy so that they may quickly and accurately identify the occluded branch. With this, they not only aid in making a correct diagnosis but also facilitate treatment planning.</p></span></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Authorship</span><p id="par0185" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="lis0010"><li class="elsevierStyleListItem" id="lsti0025"><span class="elsevierStyleLabel">1</span><p id="par0125" class="elsevierStylePara elsevierViewall">Responsible for study integrity: SMM, MPP.</p></li><li class="elsevierStyleListItem" id="lsti0030"><span class="elsevierStyleLabel">2</span><p id="par0130" class="elsevierStylePara elsevierViewall">Study concept: SMM, MPP</p></li><li class="elsevierStyleListItem" id="lsti0035"><span class="elsevierStyleLabel">3</span><p id="par0135" class="elsevierStylePara elsevierViewall">Study design: SMM, MPP</p></li><li class="elsevierStyleListItem" id="lsti0040"><span class="elsevierStyleLabel">4</span><p id="par0140" class="elsevierStylePara elsevierViewall">Data collection: SMM, MPP.</p></li><li class="elsevierStyleListItem" id="lsti0045"><span class="elsevierStyleLabel">5</span><p id="par0145" class="elsevierStylePara elsevierViewall">Data analysis and interpretation: SMM, MPP.</p></li><li class="elsevierStyleListItem" id="lsti0050"><span class="elsevierStyleLabel">6</span><p id="par0150" class="elsevierStylePara elsevierViewall">Statistical processing:</p></li><li class="elsevierStyleListItem" id="lsti0055"><span class="elsevierStyleLabel">7</span><p id="par0155" class="elsevierStylePara elsevierViewall">Literature search:</p></li><li class="elsevierStyleListItem" id="lsti0060"><span class="elsevierStyleLabel">8</span><p id="par0160" class="elsevierStylePara elsevierViewall">Drafting of the article: SMM, MPP</p></li><li class="elsevierStyleListItem" id="lsti0065"><span class="elsevierStyleLabel">9</span><p id="par0165" class="elsevierStylePara elsevierViewall">Critical review of the manuscript with intellectually significant contributions: SMM, MPP, SGO, JCF.</p></li><li class="elsevierStyleListItem" id="lsti0070"><span class="elsevierStyleLabel">10</span><p id="par0170" class="elsevierStylePara elsevierViewall">Approval of the final version: SMM, MPP, SGO, JCF.</p></li></ul></p><p id="par0175" class="elsevierStylePara elsevierViewall">A review of the anatomy of the middle cerebral artery for the era of thrombectomy: a radiologic tool based on CT angiography and perfusion CT</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Conflicts of interest</span><p id="par0180" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:10 [ 0 => array:3 [ "identificador" => "xres1612102" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec1441430" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres1612103" "titulo" => "Resumen" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec1441429" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction: why is a review of the middle cerebral artery important?" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "MCA: segments" ] 6 => array:3 [ "identificador" => "sec0015" "titulo" => "MCA: branches" "secciones" => array:6 [ 0 => array:2 [ "identificador" => "sec0020" "titulo" => "Anatomical variability of the middle cerebral artery" ] 1 => array:2 [ "identificador" => "sec0025" "titulo" => "Early branches" ] 2 => array:2 [ "identificador" => "sec0030" "titulo" => "Division of the main trunk" ] 3 => array:2 [ "identificador" => "sec0035" "titulo" => "Dominance of the divisions" ] 4 => array:2 [ "identificador" => "sec0040" "titulo" => "Abnormalities of the middle cerebral artery" ] 5 => array:2 [ "identificador" => "sec0045" "titulo" => "Anatomical/radiological tool based on CT angiography and CT perfusion" ] ] ] 7 => array:2 [ "identificador" => "sec0050" "titulo" => "Authorship" ] 8 => array:2 [ "identificador" => "sec0055" "titulo" => "Conflicts of interest" ] 9 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2021-01-07" "fechaAceptado" => "2021-07-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec1441430" "palabras" => array:5 [ 0 => "Anatomy" 1 => "Middle cerebral artery" 2 => "Stroke" 3 => "CT angiography" 4 => "Perfusion CT" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec1441429" "palabras" => array:5 [ 0 => "Anatomía" 1 => "Arteria cerebral media" 2 => "Ictus" 3 => "Angio-TC" 4 => "TC perfusión" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">The middle cerebral artery (MCA) is one of the principal intracranial vessels. It is also the one that is most often involved in ischemic cerebrovascular disease, which accounts for a significant volume of brain imaging tests. With recent updates in the management of ischemic stroke (including intravascular treatment in increasingly distal vessels and in an increasingly widening spectrum of patients), it is becoming more important to know the details of the cerebral vascular anatomy to reach accurate diagnoses quickly and thereby improve patients’ prognoses. For these reasons, we present this anatomic review of the MCA, reviewing its segments and anatomic limits, its branching patterns, and its anatomic variants. We also provide a radiologic tool based on correlations between CT angiography and perfusion CT to facilitate the identification of the points of occlusion within the branches of the MCA, taking into account its different variants.</p></span>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">La arteria cerebral media es uno de los principales vasos intracraneales y el más implicado en la patología cerebrovascular isquémica, la cual constituye un importante volumen de nuestras exploraciones. Con las últimas actualizaciones en el manejo del ictus isquémico (que implican tratamiento intravascular sobre vasos cada vez más distales y en un espectro de pacientes cada vez más amplio) se hace más importante conocer al detalle la anatomía vascular cerebral, para poder establecer diagnósticos rápidos y certeros y mejorar así el pronóstico de los pacientes. Por ello, realizamos este repaso anatómico de la arteria cerebral media, revisando sus segmentos y límites anatómicos, sus patrones de ramificación y sus variantes anatómicas. A su vez, proporcionamos una herramienta radiológica basada en la correlación entre la angio-TC y la TC perfusión para facilitar la identificación de los puntos de oclusión dentro del árbol vascular de la arteria cerebral media teniendo en cuenta sus diferentes variantes.</p></span>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Medrano-Martorell S, Pumar-Pérez M, González-Ortiz S, Capellades-Font J. Repaso anatómico de la arteria cerebral media en la era de la trombectomía: una herramienta radiológica basada en la angio-TC y la TC perfusión. Radiología. 2021;63:505–511.</p>" ] ] "multimedia" => array:10 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2324 "Ancho" => 1675 "Tamanyo" => 173946 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0035" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Diagram of the spatial/anatomical distribution of the segments of the middle cerebral artery (MCA) along its intracranial course. M1 segment (in red), M2 segment (in blue), M3 segment (in green) and M4 segment (in yellow).</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1144 "Ancho" => 1740 "Tamanyo" => 262510 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0040" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Representation of the approximate spatial/anatomical arrangement of the segments of the MCA in axial and sagittal computed tomography (CT) slices. 2.1) M1 segment in red. 2.2) M2 segment in blue. 2.3) M3 segment in green. 2.4) M4 segment in yellow.</p>" ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1304 "Ancho" => 1740 "Tamanyo" => 243582 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0045" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Three-dimensional image of the brain with the regions of blood supply corresponding to each cortical branch and representation of the spatial/anatomical arrangement of the different cortical branches in axial and sagittal CT slices with their corresponding regions of blood supply.</p>" ] ] 3 => array:8 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 1678 "Ancho" => 2508 "Tamanyo" => 417810 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0050" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Anatomical variability of the MCA.</p>" ] ] 4 => array:8 [ "identificador" => "fig0025" "etiqueta" => "Figure 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 538 "Ancho" => 1255 "Tamanyo" => 97657 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0055" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Examples of CT angiography (4.1) and digital angiography (4.2 and 4.3) with early branches (red arrows) emerging prior to the bifurcation of the MCA (green arrows).</p>" ] ] 5 => array:8 [ "identificador" => "fig0030" "etiqueta" => "Figure 6" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr6.jpeg" "Alto" => 290 "Ancho" => 1255 "Tamanyo" => 43472 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0060" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Examples of bifurcation of both MCAs on CT angiography (5.1), trifurcation of the right MCA on CT angiography (5.2) and monofurcation of the left MCA on magnetic resonance (MR) angiography (5.3).</p>" ] ] 6 => array:8 [ "identificador" => "fig0035" "etiqueta" => "Figure 7" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr7.jpeg" "Alto" => 194 "Ancho" => 2500 "Tamanyo" => 54690 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0065" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Diagram of the most common cases with respect to dominance of the divisions of the MCA, with the region of blood supply corresponding to each division. 6.1) No dominance (the branches that supply blood to the parietal lobe arise from the two divisions). 6.2) Anterosuperior dominance (the blood supply to the parietal lobe comes from the anterosuperior branch, along with the blood supply to the frontal lobe). 6.3) Posteroinferior dominance (the blood supply to the parietal lobe comes from the posteroinferior branch, along with the blood supply to the temporal lobe). 6.4) Trifurcation with no dominance (each lobe is supplied with blood by one of the three divisions).</p>" ] ] 7 => array:8 [ "identificador" => "fig0040" "etiqueta" => "Figure 8" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr8.jpeg" "Alto" => 1158 "Ancho" => 2508 "Tamanyo" => 172629 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0070" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Cortical branches corresponding to each lobe of the brain and most common possibilities with respect to dominance, as well as branches that may emerge as early.</p>" ] ] 8 => array:8 [ "identificador" => "fig0045" "etiqueta" => "Figure 9" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr9.jpeg" "Alto" => 2564 "Ancho" => 1675 "Tamanyo" => 500705 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0075" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Case 1: an 87-year-old man with a right partial anterior circulation infarction (PACI). 8.1) Baseline CT with hypodensity in left M2 and M5 areas, Alberta stroke programme early CT score (ASPECTS) 8. 8.2) CT perfusion (Tmax map) with time delay in the corticosubcortical area corresponding to left precentral branch. 8.3) CT angiography in axial and sagittal slices: opacification is seen to stop at the left precentral branch (red arrow).</p>" ] ] 9 => array:8 [ "identificador" => "fig0050" "etiqueta" => "Figure 10" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr10.jpeg" "Alto" => 2362 "Ancho" => 1675 "Tamanyo" => 524347 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0080" "detalle" => "Figure 1" "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Case 2: a 69-year-old man with a left total anterior circulation infarction (TACI). 9.1) Baseline CT with no abnormalities, ASPECTS 10. 9.2) CT angiography showing bifurcation of the trunks of both MCAs (blue arrows) with their anteroinferior (red asterisk) and posterosuperior divisions (yellow asterisk) and revealing dominance on the part of the latter given its larger calibre compared to the former. Both MCAs, for their parts, have early branches (brown arrows). A filling defect is seen around the bifurcation of the left MCA (green arrow). 9.3) CT perfusion (Tmax map), time delay in parietal, medial temporal and posterior temporal regions, indicating that only the dominant (posteroinferior) division of the left MCA has been affected.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:17 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Angiografía cerebral" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. 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