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Inicio Radiología (English Edition) Oral versus intravenous beta-blockers for computed tomography coronary angiograp...
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Vol. 53. Issue 3.
Pages 254-260 (January 2011)
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Vol. 53. Issue 3.
Pages 254-260 (January 2011)
Oral versus intravenous beta-blockers for computed tomography coronary angiography? A randomized controlled trial
¿Betabloqueante oral o intravenoso en coronariografía mediante tomografía computarizada? Un estudio prospectivo y aleatorizado
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G. Tardáguila de la Fuente
Corresponding author
gonzatar@gmail.com

Corresponding author.
, C. Delgado Sánchez-Gracián, J.A. Aguilar Arjona, R. Prada González, G. Fernández Pérez, F. Tardáguila Montero
Servicio de Radiología, Hospital POVISA, Vigo, Pontevedra, Spain
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Abstract
Objectives

To determine whether the time employed in the radiological management of outpatients undergoing computed tomography (CT) coronary angiography varies in function of whether oral or intravenous beta-blockers are administered.

Material and methods

This was a prospective, analytical, randomized controlled trial. A total of 40 patients with heart rates greater than 65 beats per minute were randomly assigned to one of two groups. Patients in group 1 were administered oral beta-blockers and patients in group 2 were administered intravenous beta-blockers. We measured the overall time from entry to the radiology department to exit from the CT examination room. We also measured heart rate, blood pressure, and the number of conclusive studies.

Results

The median (interquartile range) overall time was 120 (100–150) minutes in the 19 patients who received oral beta-blockers compared to 35 (27.5–67.5) minutes in the 21 patients who received intravenous beta-blockers (p < 0.001). The median time that patients were in the CT examination room was 10 (6–15) minutes in Group 1 and 10 (9–20) minutes in Group 2 (p=0.57). The decrease in mean arterial pressure was 10mmHg after the administration of intravenous beta-blockers compared to 3.3mmHg after the administration of oral beta-blockers (p=0.01). No significant differences were found in the diagnostic quality of the examinations.

Conclusions

The time employed in the radiological management of patients undergoing CT coronary angiography is significantly lower when beta-blockers are administered intravenously. There was no difference in the time patients were in the CT examination room or in the diagnostic quality of the examinations.

Keywords:
Beta-blockers
Computed tomography
Coronary vessels
Heart
Heart rate
Resumen
Objetivos

Estudiar si existen diferencias en los tiempos empleados en la atención al paciente, según se utilice la vía oral o intravenosa en la administración de betabloqueantes a pacientes ambulatorios sometidos a coronariografía mediante tomografía computarizada (TC).

Material y métodos

Estudio prospectivo, analítico, aleatorizado y controlado. Se distribuye a 40 pacientes con frecuencia mayor de 65 latidos por minuto en 2 grupos. En el grupo 1 se administra el betabloqueante por vía oral y en el grupo 2 por vía intravenosa. Se mide el tiempo global transcurrido desde la entrada del paciente en Radiología hasta su marcha y el tiempo parcial de ocupación de sala desde que entra hasta que sale de la sala de TC. Variables secundarias: frecuencia cardíaca, tensión arterial y número de estudios concluyentes.

Resultados

La mediana (rango intercuartílico) del tiempo global fue de 120 minutos (100–150) en los 19 pacientes betabloqueados por vía oral y de 35 minutos (27,5–67,5) en los 21 pacientes con medicación intravenosa (p < 0,001). El tiempo parcial de ocupación de sala fue 10 minutos (6–15) en el grupo 1 y 10 minutos (9–20) en el grupo 2 (p=0,57). El descenso de la tensión arterial media es 10mmHg con los betabloqueantes por vía intravenosa frente a 3,3mmHg por la vía oral (p=0,01). No se hallaron diferencias significativas en la calidad diagnóstica de las exploraciones.

Conclusiones

El tiempo de atención al paciente es significativamente menor con la administración intravenosa de betabloqueantes. No se demostraron diferencias en el tiempo de ocupación de sala ni en la calidad diagnóstica.

Palabras clave:
Antagonistas beta adrenérgicos
Tomografía computarizada
Vasos coronarios
Corazón
Frecuencia cardíaca

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