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Inicio Revista Colombiana de Reumatología (English Edition) Patients with psoriatic arthritis followed in tertiary centers in Southern Brazi...
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Vol. 31. Issue 3.
Pages 283-289 (July - September 2024)
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Vol. 31. Issue 3.
Pages 283-289 (July - September 2024)
Original Investigation
Patients with psoriatic arthritis followed in tertiary centers in Southern Brazil have a high prevalence of metabolic syndrome
Los pacientes con artritis psoriásica seguidos en centros de tercer nivel en el sur de Brasil tienen una alta prevalencia de síndrome metabólico
Lilian Rodrigues Henriquea,
Corresponding author
, Ariele Lima de Melloa, Charles Lubianca Kohema,b, Franciele de Almeida Menegatb, Ana Paula Beckhauser de Camposc,d, Juliana Simionic, Thelma Larocca Skarec,d, Isadora Emygdio Gavad, Juliah Serragliod, Aline Castello Branco Mancusoe, Fabíola Satlerf, Penélope Esther Palominosb
a Faculty of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil
b Rheumatology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
c Rheumatology Service, Hospital Universitário Evangélico Mackenzie, Curitiba, Brazil
d Evangelical College Mackenzie, Curitiba, Brazil
e Biostatistics Unit – Research Board, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
f Endocrinology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
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Table 1. Characteristics of the PsA patients included in the study.
Abstract
Introduction/Objective

Patients with psoriatic arthritis (PsA) have a significant prevalence of metabolic syndrome (MS), however studies conducted in Latin America describing comorbidities of PsA patients are still scarce. The aim of the present work was to estimate the prevalence of MS in patients attending PsA clinics in tertiary university centers in the south region of Brazil and to evaluate the achievement of the minimal disease activity criteria among those with and without MS.

Materials and methods

A cross-sectional study was conducted; patients were recruited in two university hospitals and data collected during a routine clinic visit. The prevalence of MS was estimated using the National Cholesterol Education Programme's Adult Treatment Panel III (NCEP/ATP III). The prevalence of patients achieving the MDA criteria was compared between individuals with and without MS using Chi-square test.

Results

One hundred and five patients with PsA were evaluated, 81 in center A (Rio Grande do Sul) and 24 in center B (Paraná); 54.3% were female (N=57), the average age was 55.7 (SD 11.6) years and the median time of diagnosis in years was 7.4 (.16–42.2). A total of 51.9% (N=54) were diagnosed with MS., hypertension was found in 51.4% (N=54) and obesity in 38.1% (N=40) of the sample. There was no statistically significant association between MS and MDA.

Conclusion

Patients followed in PsA clinics in university tertiary centers in the south of Brazil have a significant prevalence of MS. This work emphasizes the importance of the screening and treatment of comorbidities in PsA.

Keywords:
Psoriatic arthritis
Metabolic syndrome
Obesity
Minimal disease activity
Resumen
Introducción/Objetivo

Los pacientes con artritis psoriásica (APs) tienen una prevalencia significativa de síndrome metabólico (SM), pero los estudios realizados en América Latina que describen las comorbilidades asociadas con esta enfermedad son escasos. El objetivo del presente trabajo fue estimar la prevalencia de SM en pacientes que asisten a clínicas de APs en centros universitarios de tercer nivel en la región sur de Brasil y evaluar el cumplimiento de los criterios mínimos de actividad de la enfermedad (MDA) entre aquellos con y sin SM.

Materiales y métodos

Se llevó a cabo un estudio transversal con pacientes reclutados en dos hospitales universitarios; los datos se recopilaron durante una visita clínica de rutina. La prevalencia de SM se estimó utilizando el Panel III de Tratamiento para Adultos del Programa Nacional de Educación sobre el Colesterol (NCEP-ACT III). La prevalencia de pacientes que alcanzaron los criterios de MDA se comparó entre individuos con y sin SM mediante la prueba de chi-cuadrado.

Resultados

Se evaluaron 105 pacientes con APs, 81 en el centro A (Rio Grande do Sul) y 24 en el centro B (Paraná); 57 (54,3%) eran del sexo femenino, la edad promedio fue de 55,7 (DE: 11,6) años y la mediana del tiempo de diagnóstico en años fue de 7,4 (0,16-42,2). Un total de 54 (51,9%) individuos fueron diagnosticados con SM, y se encontró hipertensión también en 54 (51,4%) y obesidad en 40 (38,1%) de ellos. No hubo una asociación estadísticamente significativa entre SM y MDA.

Conclusión

Los pacientes seguidos en clínicas de APs en centros universitarios de tercer nivel en el sur de Brasil tienen una prevalencia significativa de SM. Este trabajo enfatiza la importancia del cribado y del tratamiento de las comorbilidades en la APs.

Palabras clave:
Artritis psoriásica
Síndrome metabólico
Obesidad
Mínima actividad de la enfermedad

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