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About a case" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "129" "paginaFinal" => "131" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Elisa Hernández García, Manuel Alfonso Aparcero Fernández del Campo, Agustín Sibón Olano, Alba Esparrago de Mingo" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Elisa" "apellidos" => "Hernández García" "email" => array:1 [ 0 => "manuelaparcero@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cr0005" ] ] ] 1 => array:3 [ "nombre" => "Manuel Alfonso" "apellidos" => "Aparcero Fernández del Campo" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "af0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "af0015" ] ] ] 2 => array:3 [ "nombre" => "Agustín" "apellidos" => "Sibón Olano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "af0010" ] ] ] 3 => array:3 [ "nombre" => "Alba" "apellidos" => "Esparrago de Mingo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "af0020" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Instituto de Medicina Legal y Ciencias Forenses de Madrid, San Lorenzo del El Escorial, Madrid, Spain" "etiqueta" => "a" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Instituto de Medicina Legal y Ciencias Forense de Cádiz, Cádiz, Spain" "etiqueta" => "b" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Departamento de Anatomía Patológica, Biología Celular, Histología, Historia de la Ciencia y Medicina Legal y Forense y Toxicología, Facultad de Medicina, Universidad de Cádiz, Cádiz, Spain" "etiqueta" => "c" "identificador" => "af0015" ] 3 => array:3 [ "entidad" => "Servicio de Histopatología, Instituto Nacional de Toxicología y Ciencias Forenses, Las Rozas, Madrid, Spain" "etiqueta" => "d" "identificador" => "af0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Aneurisma coronario gigante. Una entidad rara y un hallazgo inusual en la práctica forense. A propósito de un aso" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "f0025" "etiqueta" => "Fig. 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 693 "Ancho" => 969 "Tamanyo" => 131944 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0025" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">Cross-sectional transverse views of both cardiac ventricles. Myocardial scarring on the posterior wall of the left ventricle, posterior septum, and posterior wall of the right ventricle, linked to chronic ischaemic heart disease.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="p0005" class="elsevierStylePara elsevierViewall">We report the case of a 58-year-old male with a history of acute myocardial infarction (AMI) in 2005, treated with thrombolysis with satisfactory results. He suffered re-infarction 8 months later which was treated with balloon coronary angioplasty in the posterior descending coronary artery and 2 inferior AMIs in 2008 and 2011, which were treated successfully with fibrinolysis. The coronary angiography performed in 2005 evidenced the presence of ectasia in the left main coronary artery and a 1-cm aneurysm in the right coronary artery (RCA). Follow-up was irregular and the patient discontinued the anticoagulation regimen (acenocoumarol). In 2019, he was found deceased in his home. A medical-forensic autopsy was performed that revealed saccular dilatation of the RCA (<a class="elsevierStyleCrossRef" href="#f0005">Fig. 1</a>), oedema, and pulmonary congestion. The rest of the autopsy yielded no further findings of forensic interest. The histopathological study detected an RCA that displayed a circuitous course and aneurysmal dilation that measured 3 cm along its maximum axis in the middle and distal segment that contained an acute occlusive thrombosis (<a class="elsevierStyleCrossRefs" href="#f0010">Figs. 2, 3, and 4</a>), extensive biventricular myocardial scarring (<a class="elsevierStyleCrossRef" href="#f0025">Fig. 5</a>), cardiac hypertrophy, and severe atheromatosis involving several vessels. Toxicological studies of the blood and vitreous humour were negative.</p><elsevierMultimedia ident="f0005"></elsevierMultimedia><elsevierMultimedia ident="f0010"></elsevierMultimedia><elsevierMultimedia ident="f0015"></elsevierMultimedia><elsevierMultimedia ident="f0020"></elsevierMultimedia><elsevierMultimedia ident="f0025"></elsevierMultimedia><p id="p0010" class="elsevierStylePara elsevierViewall">Coronary artery aneurysms (CAAs) are a rare condition with a prevalence rate of 0.3–5.3%.<a class="elsevierStyleCrossRef" href="#bb0005"><span class="elsevierStyleSup">1</span></a> Giant CAAs have a prevalence rate of between 0.02<a class="elsevierStyleCrossRef" href="#bb0010"><span class="elsevierStyleSup">2</span></a> and 0.2%.<a class="elsevierStyleCrossRef" href="#bb0005"><span class="elsevierStyleSup">1</span></a> With no clear consensus regarding its definition, such aneurysms are designated as giant when the dilated segment is fourfold the diameter of the adjacent segment or when the dilatation exceeds 8 mm.<a class="elsevierStyleCrossRef" href="#bb0015"><span class="elsevierStyleSup">3</span></a></p><p id="p0015" class="elsevierStylePara elsevierViewall">In order of frequency, the vessels most often involved are the RCA, the anterior descending coronary artery, the circumflex artery, and the left main coronary artery.<a class="elsevierStyleCrossRef" href="#bb0020"><span class="elsevierStyleSup">4</span></a></p><p id="p0020" class="elsevierStylePara elsevierViewall">The most common cause of CCA is atherosclerotic coronary artery disease; other causes have been reported, such as Takayasu's arteritis, congenital heart disease, connective tissue disease, percutaneous coronary interventions, and Kawasaki disease, this last condition being the single most predominant cause in children and young adults. Multiple vessels are also often affected.<a class="elsevierStyleCrossRef" href="#bb0025"><span class="elsevierStyleSup">5</span></a></p><p id="p0025" class="elsevierStylePara elsevierViewall">Most CAs are incidental findings on coronary angiographic studies.<a class="elsevierStyleCrossRef" href="#bb0005"><span class="elsevierStyleSup">1</span></a> Their clinical spectrum varies widely, from asymptomatic patients to episodes of sudden death, most often associated with thrombosis, distal embolization, and ischaemic heart disease; fatal arrhythmias due to involvement of the nodal branches of the coronary arteries are also not inconsiderable.</p><p id="p0030" class="elsevierStylePara elsevierViewall">In the case of giant CAAs, the treatment of choice is surgical, so as to prevent potentially fatal complications.</p><p id="p0035" class="elsevierStylePara elsevierViewall">Final diagnosis: Giant aneurysm of the RCA with acute occlusive thrombosis. Chronic ischaemic heart disease.</p><span id="s0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0015">Funding</span><p id="p0040" class="elsevierStylePara elsevierViewall">The authors state that this study has not received any funding.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "s0005" "titulo" => "Funding" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="np4005">Please cite this article as: Hernández García E, Aparcero Fernández del Campo MA, Sibón Olano A, Esparrago de Mingo A. Giant coronary aneurysm. A rare entity and an unusual finding in forensic practice. About a case. Revista Española de Medicina Legal. 2024. <span class="elsevierStyleInterRef" id="ir3005" href="https://doi.org/10.1016/j.remle.2024.05.002">https://doi.org/10.1016/j.remle.2024.05.002</span>.</p>" ] ] "multimedia" => array:5 [ 0 => array:8 [ "identificador" => "f0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1162 "Ancho" => 827 "Tamanyo" => 146880 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Nodular area measuring 6 x 5 x 3 cm of the right coronary artery (RCA).</p>" ] ] 1 => array:8 [ "identificador" => "f0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 666 "Ancho" => 827 "Tamanyo" => 103667 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Sagittal view. Aneurysmatic dilation and thrombus in its interior.</p>" ] ] 2 => array:8 [ "identificador" => "f0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1009 "Ancho" => 827 "Tamanyo" => 149505 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0015" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Close-up of the aneurysmatic dilation and the acute thrombosis contained within it.</p>" ] ] 3 => array:8 [ "identificador" => "f0020" "etiqueta" => "Fig. 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 828 "Ancho" => 827 "Tamanyo" => 83846 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0020" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">Please note the difference in diameter between the proximal segment (black arrow) and the middle and distal segment of the right coronary artery. Please also observe the presence of occlusive thrombosis in both segments of the right coronary artery.</p>" ] ] 4 => array:8 [ "identificador" => "f0025" "etiqueta" => "Fig. 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 693 "Ancho" => 969 "Tamanyo" => 131944 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0025" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">Cross-sectional transverse views of both cardiac ventricles. Myocardial scarring on the posterior wall of the left ventricle, posterior septum, and posterior wall of the right ventricle, linked to chronic ischaemic heart disease.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant coronary artery aneurysms: review and update" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.D. Crawley" 1 => "W.J. Mahlow" 2 => "D. Russell Huntsinger" 3 => "S. Afiniwala" 4 => "D.C. 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Picard" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.acvd.2019.10.008" "Revista" => array:8 [ "tituloSerie" => "Arch Cardiovasc Dis" "fecha" => "2020" "volumen" => "113" "numero" => "1" "paginaInicial" => "59" "paginaFinal" => "69" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31866173" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0006497122006954" "estado" => "S300" "issn" => "00064971" ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant coronary artery aneurysms involving more than one coronary artery: case report" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.S. Khouzam" 1 => "N. 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Journal Information
Vol. 50. Issue 3.
Pages 129-131 (July - September 2024)
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Vol. 50. Issue 3.
Pages 129-131 (July - September 2024)
Images in legal medicine
Giant coronary aneurysm. A rare entity and an unusual finding in forensic practice. About a case
Aneurisma coronario gigante. Una entidad rara y un hallazgo inusual en la práctica forense. A propósito de un aso
Elisa Hernández Garcíaa,
, Manuel Alfonso Aparcero Fernández del Campob,c, Agustín Sibón Olanob, Alba Esparrago de Mingod
Corresponding author
a Instituto de Medicina Legal y Ciencias Forenses de Madrid, San Lorenzo del El Escorial, Madrid, Spain
b Instituto de Medicina Legal y Ciencias Forense de Cádiz, Cádiz, Spain
c Departamento de Anatomía Patológica, Biología Celular, Histología, Historia de la Ciencia y Medicina Legal y Forense y Toxicología, Facultad de Medicina, Universidad de Cádiz, Cádiz, Spain
d Servicio de Histopatología, Instituto Nacional de Toxicología y Ciencias Forenses, Las Rozas, Madrid, Spain
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