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Inicio Revista Española de Nutrición Humana y Dietética Papel de los antioxidantes en la prevención del cáncer
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Vol. 16. Issue 1.
Pages 16-24 (January - March 2012)
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Vol. 16. Issue 1.
Pages 16-24 (January - March 2012)
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Papel de los antioxidantes en la prevención del cáncer
Role of antioxidants in the prevention of cancer
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13511
Laura Llacunaa,
Corresponding author
laurallacuna@hotmail.com

Autor para correspondencia.
, Nuria Macha,b
a Estudis de Ciències de la Salut, Universitat Oberta de Catalunya (UOC), Barcelona, España
b Animal Breeding and Genomics Centre, Wageningen UR Livestock Research, Lelystad, Países Bajos
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Resumen

La naturaleza de la asociación entre radicales libres y cáncer es compleja y paradójica. Parece que los radicales libres y el estrés oxidativo pueden inducir cáncer, pero al mismo tiempo las células transformadas, es decir, las células cancerosas, generan más radicales libres que las células normales. Compuestos endógenos antioxidantes, entre ellos el glutatión y la lisozima, pueden limitar los efectos del estrés oxidativo; sin embargo, dichos sistemas pueden ser rápidamente acaparados por elevadas cantidades de radicales libres. De ahí la importancia de incrementar la concentración de antioxidantes de la célula para prevenir posibles agentes adversos que podrían llegar a originar un proceso canceroso. Una buena alimentación, así como conocer y emplear alimentos con propiedades antioxidantes, puede ser de gran ayuda para la prevención del cáncer.

Palabras clave:
Cáncer
Radicales libres
Antioxidantes
Lisozima
Glutatión
Abstract

The nature of the association between free radicals and cancer is complex and paradoxical, as it seems that free radicals and oxidative stress can induce cancer, but at the same time the transformed cells, that is, the cancer cells generate more free radicals than normal cells. Endogenous antioxidant compounds, including glutathione and lysozyme, can limit the effects of oxidative stress, but these systems can be quickly saturated by high amounts of free radicals. It is important to increase the cellular levels of antioxidants that could provide protection against possible adverse agents that can cause a cell cancer. A good diet and the knowledge of several compounds of foods with antioxidant effects may be helpful to prevent cancer disease.

Keywords:
Cancer
Free radicals
Antioxidant
Lysozyme
Glutathione
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