Predictors of effusion viscosity in otitis media with effusion: neutrophil lymphocyte ratio versus mean platelet volume

Abstract

Objetivos

comparar entre el índice de neutrófilos linfocitos (NLR) y el volumen plaquetario medio (VPM) en la predicción de la viscosidad del derrame en la otitis media con derrame.

Materiales y métodos

Se incluyeron en el estudio 248 niños con derrame en el oído medio. Se evaluaron los hemogramas completos (CBC) preoperatorios. Se registraron los valores de NLR y MPV. La viscosidad del derrame se evaluó durante la cirugía mientras se aspiraba el derrame después de la miringotomía. Se clasificaron 2 tipos de derrames; tipos serosos y mucoides.

Resultados

se reportaron diferencias estadísticamente significativas en NLR y MPV entre los derrames serosos y mucoides. Los valores de corte de NLR y MPV para diferenciar entre derrames serosos y mucoides fueron 1,21 y 7,95 respectivamente. Cuando se compararon NLR y MPV, NLR pareció tener mayor sensibilidad, especificidad y precisión diagnóstica que MPV.

Conclusión

NLR es superior a MPV como predictor de la viscosidad del derrame en otitis media con derrame. Ambos marcadores se consideran rentables y fiables para la evaluación de la viscosidad del derrame.

Resumen

Objectives

to compare between neutrophil lymphocyte ratio (NLR) and mean platelet volume (MPV) in prediction of the viscosity of the effusion in otitis media with effusion.

Materials and methods

248 children with middle ear effusion were included in the study. Preoperative complete blood counts (CBCs) were evaluated. The values of NLR and MPV were recorded. The viscosity of the effusion was evaluated during surgery while the effusion was aspirated after myringotomy. Accordingly, 2 types of effusions were classified; serous and mucoid types.

Results

Statistically significant differences in NLR and MPV between serous and mucoid types were reported. The cut-off values for NLR and MPV to differentiate between serous and mucoid effusions were 1.21 and 7.95 respectively. When NLR and MPV were compared, NLR appeared to have higher sensitivity, specificity, and accuracy than MPV.

Conclusion

NLR is superior to MPV as a predictor of the viscosity of the effusion in otitis media with effusion. Both markers are considered cost-effective and reliable markers for evaluation of the effusion viscosity.