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"documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Acta Otorrinolaringol Esp. 2002;53:321-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2344 "formatos" => array:3 [ "EPUB" => 25 "HTML" => 1519 "PDF" => 800 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Estabilidad de los umbrales de audición durante las primeras 5 semanas post-estapedectomía" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "321" "paginaFinal" => "325" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Stability of auditory thresholds in the first 5 weeks following stapedectomy" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "G.L. Morín Murillo, K. Jáuregui Renaud, E.G. Zepeda López, S. del Castillo Mendoza, A. Bello Mora" "autores" => array:5 [ 0 => array:2 [ "nombre" => "G.L." "apellidos" => "Morín Murillo" ] 1 => array:2 [ "nombre" => "K." "apellidos" => "Jáuregui Renaud" ] 2 => array:2 [ "nombre" => "E.G." "apellidos" => "Zepeda López" ] 3 => array:2 [ "nombre" => "S." "apellidos" => "del Castillo Mendoza" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Bello Mora" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001651902783167?idApp=UINPBA00004N" "url" => "/00016519/0000005300000005/v1_201304231348/S0001651902783167/v1_201304231348/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Gentamicina intratimpánica en tratamiento de la enfermedad de ménière: resultados preliminares" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "326" "paginaFinal" => "332" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "C. Marín Garrido, J. Fraile Rodrigo, M.J. Naya Gálvez, L. Carmen Samperiz, E. Hernández Montero, A. Ortiz García" "autores" => array:6 [ 0 => array:4 [ "nombre" => "C." "apellidos" => "Marín Garrido" "email" => array:1 [ 0 => "crismaring@yahoo.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">†</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Fraile Rodrigo" ] 2 => array:2 [ "nombre" => "M.J." "apellidos" => "Naya Gálvez" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Carmen Samperiz" ] 4 => array:2 [ "nombre" => "E." "apellidos" => "Hernández Montero" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Ortiz García" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Hospital universitario “miguel servet” de zaragoza" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "†" "correspondencia" => "Correspondencia: C/ Gran Vía, 24 - 5° Dcha. 50005 Zaragoza" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Intratympanic gentamycin for the treatment of ménière’s disease" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2001-09-10" "fechaAceptado" => "2002-02-04" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras Clave" "identificador" => "xpalclavsec79717" "palabras" => array:2 [ 0 => "Gentamicina intratimpánica" 1 => "Enfermedad de Ménière" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec79718" "palabras" => array:2 [ 0 => "Intratympanic gentamycin" 1 => "Ménière’s disease" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">En la mayoría de los pacientes con Enfermedad de Ménière, el tratamiento médico es suficiente para controlar los síntomas, sin embargo, en un pequeño porcentaje, la intensidad y la frecuencia de las crisis hacen necesario adoptar medidas más agresivas, entre ellas la administración de aminoglucósidos por vía local o sistémica, o bien procedimientos quirúrgicos. Hemos realizado un estudio descriptivo longitudinal y prospectivo de la respuesta al tratamiento con gentamicina intratimpánica, en 24 pacientes diagnosticados de Enfermedad de Ménière en el Servicio de ORL del Hospital "Miguel Servet" en los dos últimos años, tras más de un año de tratamiento médico inefectivo. Se revisa la eficacia en cuanto a frecuencia de crisis de vértigo, media de audición, audiometría verbal y nivel funcional. Hemos obtenido un buen resultado en cuanto al control del vértigo (clase A y B de los criterios de objetivación según el índice de mejoría tras tratamiento) en 16 de los 24 pacientes (66,6%) (13 clase A con desaparición total de las crisis y 3 clase B) y un resultado aceptable (clase C) en tres (12,5%). El resultado fue malo (clase D y E), con necesidad de pasar a tratamiento quirúrgico en otros cinco pacientes (20,83%). Evaluamos la gentamicina intratimpánica como tratamiento alternativo a técnicas más agresivas, y lo consideramos un tratamiento eficaz, con poco riesgo y escasas complicaciones en la Enfermedad de Ménière no controlada farmacológicamente.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">In the majority of patients suffering of Ménière's disease, medical treatment is sufficient to control symptoms, albeit, in a small number of them, the high intensity and frequency of vertigo spells makes necessary to adopt more aggresive measures, like intratympanic or general aminoglycoside administration, as well as surgical procedures. We present a prospective and longitudinal descriptive study with the results of intratympanic gentamycin in 24 patients labeled of Ménière's disease in the Otolaryngology Department of "Miguel Servet Hospital" in the last two years, after a followup period of more than a year, during which controlled medical treatment had been proved unsuccesful. We go over the efficacy in terms of frequency of vertigo crisis, audition average, logoaudiometry and functional level. We obtained good results over vertigo control (types A and B of the objective criteria based in the improvement index after treatment) in 16 out of the 24 patients (66.6%), (13 were type A with total absence of crisis and 3 were type B) and an acceptable result (type C) in three of them (12.5.%). In the other five patients (20.83%)results were disappointing (types D and E) compeling to apply surgical treatment. We have tried to evaluate intratympanic gentamycin as an alternative treatment to more aggresive technics and we consider it to be a good option, with a low risk and scarce complications in the no pharmacologycally controlled Ménière's disease patients.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:25 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Streptomycin treatment of vertigo" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E.P. Fowler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Trans Am Acad Ophthalmol Otolaryngol" "fecha" => "1948" "volumen" => "52" "paginaInicial" => "239" "paginaFinal" => "301" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." 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año/Mes | Html | Total | |
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2024 Octubre | 0 | 14 | 14 |
2024 Septiembre | 0 | 26 | 26 |
2024 Agosto | 0 | 21 | 21 |
2024 Julio | 0 | 24 | 24 |
2024 Junio | 0 | 16 | 16 |
2024 Mayo | 0 | 10 | 10 |
2024 Abril | 0 | 11 | 11 |
2024 Marzo | 0 | 31 | 31 |
2024 Febrero | 1 | 5 | 6 |
2024 Enero | 0 | 7 | 7 |
2023 Diciembre | 0 | 11 | 11 |
2023 Noviembre | 0 | 21 | 21 |
2023 Octubre | 0 | 14 | 14 |
2023 Septiembre | 0 | 8 | 8 |
2023 Agosto | 0 | 5 | 5 |
2023 Julio | 0 | 15 | 15 |
2023 Junio | 0 | 9 | 9 |
2023 Abril | 0 | 1 | 1 |
2023 Marzo | 5 | 10 | 15 |
2023 Febrero | 0 | 15 | 15 |
2023 Enero | 2 | 13 | 15 |
2022 Diciembre | 0 | 10 | 10 |
2022 Noviembre | 0 | 10 | 10 |
2022 Octubre | 0 | 1 | 1 |
2022 Septiembre | 0 | 6 | 6 |
2022 Agosto | 0 | 8 | 8 |
2022 Julio | 1 | 7 | 8 |
2022 Junio | 0 | 6 | 6 |
2022 Mayo | 0 | 4 | 4 |
2022 Abril | 0 | 7 | 7 |
2022 Marzo | 1 | 7 | 8 |
2022 Febrero | 3 | 4 | 7 |
2022 Enero | 0 | 4 | 4 |
2021 Diciembre | 0 | 5 | 5 |
2021 Noviembre | 1 | 8 | 9 |
2021 Octubre | 0 | 5 | 5 |
2021 Septiembre | 1 | 1 | 2 |
2021 Agosto | 1 | 11 | 12 |
2021 Julio | 0 | 6 | 6 |
2021 Junio | 4 | 4 | 8 |
2021 Mayo | 1 | 2 | 3 |
2021 Abril | 0 | 1 | 1 |
2021 Marzo | 0 | 4 | 4 |
2021 Febrero | 5 | 4 | 9 |
2020 Diciembre | 0 | 6 | 6 |
2020 Noviembre | 2 | 2 | 4 |
2020 Octubre | 0 | 3 | 3 |
2020 Septiembre | 1 | 7 | 8 |
2020 Agosto | 0 | 7 | 7 |
2020 Julio | 2 | 5 | 7 |
2020 Junio | 1 | 2 | 3 |
2020 Mayo | 0 | 10 | 10 |
2020 Abril | 0 | 3 | 3 |
2020 Marzo | 41 | 14 | 55 |
2020 Febrero | 62 | 30 | 92 |
2020 Enero | 73 | 37 | 110 |
2019 Diciembre | 72 | 37 | 109 |
2019 Noviembre | 42 | 38 | 80 |
2019 Octubre | 53 | 47 | 100 |
2019 Septiembre | 86 | 46 | 132 |
2019 Agosto | 41 | 16 | 57 |
2019 Julio | 74 | 96 | 170 |
2019 Junio | 126 | 99 | 225 |
2019 Mayo | 257 | 313 | 570 |
2019 Abril | 140 | 126 | 266 |
2019 Marzo | 52 | 54 | 106 |
2019 Febrero | 78 | 51 | 129 |
2019 Enero | 37 | 35 | 72 |
2018 Diciembre | 44 | 51 | 95 |
2018 Noviembre | 48 | 62 | 110 |
2018 Octubre | 51 | 36 | 87 |
2018 Agosto | 0 | 1 | 1 |
2018 Junio | 0 | 2 | 2 |
2018 Mayo | 1 | 2 | 3 |
2018 Abril | 12 | 74 | 86 |
2018 Marzo | 7 | 32 | 39 |
2018 Febrero | 4 | 63 | 67 |
2018 Enero | 4 | 46 | 50 |
2017 Diciembre | 5 | 24 | 29 |
2017 Noviembre | 2 | 60 | 62 |
2017 Octubre | 15 | 68 | 83 |
2017 Septiembre | 8 | 70 | 78 |
2017 Agosto | 10 | 51 | 61 |
2017 Julio | 11 | 82 | 93 |
2017 Junio | 20 | 114 | 134 |
2017 Mayo | 19 | 109 | 128 |
2017 Abril | 15 | 136 | 151 |
2017 Marzo | 23 | 158 | 181 |
2017 Febrero | 14 | 125 | 139 |
2017 Enero | 10 | 124 | 134 |
2016 Diciembre | 22 | 106 | 128 |
2016 Noviembre | 31 | 125 | 156 |
2016 Octubre | 38 | 158 | 196 |
2016 Septiembre | 26 | 192 | 218 |
2016 Agosto | 20 | 103 | 123 |
2016 Julio | 17 | 37 | 54 |
2016 Junio | 26 | 123 | 149 |
2016 Mayo | 25 | 168 | 193 |
2016 Abril | 23 | 181 | 204 |
2016 Marzo | 16 | 143 | 159 |
2016 Febrero | 13 | 127 | 140 |
2016 Enero | 12 | 105 | 117 |
2015 Diciembre | 31 | 103 | 134 |
2015 Noviembre | 22 | 144 | 166 |
2015 Octubre | 19 | 135 | 154 |
2015 Septiembre | 17 | 114 | 131 |
2015 Agosto | 24 | 97 | 121 |
2015 Julio | 18 | 115 | 133 |
2015 Junio | 6 | 91 | 97 |
2015 Mayo | 15 | 55 | 70 |
2015 Abril | 19 | 45 | 64 |
2015 Marzo | 21 | 17 | 38 |
2015 Febrero | 11 | 16 | 27 |
2015 Enero | 15 | 6 | 21 |
2014 Diciembre | 9 | 9 | 18 |
2014 Noviembre | 6 | 6 | 12 |
2014 Octubre | 11 | 4 | 15 |
2014 Septiembre | 16 | 7 | 23 |
2014 Agosto | 9 | 6 | 15 |
2014 Julio | 10 | 4 | 14 |
2014 Junio | 12 | 1 | 13 |
2014 Mayo | 8 | 3 | 11 |
2014 Abril | 8 | 2 | 10 |
2014 Marzo | 6 | 3 | 9 |
2014 Febrero | 10 | 5 | 15 |
2014 Enero | 9 | 3 | 12 |
2013 Diciembre | 5 | 2 | 7 |
2013 Noviembre | 4 | 1 | 5 |
2013 Octubre | 10 | 8 | 18 |
2013 Septiembre | 4 | 9 | 13 |
2013 Agosto | 4 | 17 | 21 |
2013 Julio | 3 | 2 | 5 |
2002 Abril | 670 | 0 | 670 |