75-years old hispanic female with history of liver cirrhosis. It has been reported that the 18F-FDG PET scan of the liver can depict false negative results particularly with history of liver cirrhosis (1, 2). In this case 18F-FDG PET/CT depicted a large tumoral mass in segment VI (15.6 x 12.4 cm), there is enlargement of the liver with medial displacement of the gallbladder. Our first differential diagnosis was hepatocarcinoma, pathologic analysis of liver biopsy confirmed the diagnosis.
Figures A-C, sagittal, coronal and axial planes PET/CT fused images show a big lesion in segment VI of the liver with increased uptake of 18F-FDG, the maximun SUV was 14.5. The lesion presented two central zones of no uptake related with central necrosis. Figures D-F, oblique volumetric-3D fused PET/CT images depicting different aspects of the lesion.