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Inicio Annals of Hepatology Xanthelasmas and xanthomatas striatum palmare in primary biliary cirrhosis
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Vol. 5. Núm. 1.
Páginas 49 (enero - marzo 2006)
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Vol. 5. Núm. 1.
Páginas 49 (enero - marzo 2006)
Open Access
Xanthelasmas and xanthomatas striatum palmare in primary biliary cirrhosis
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3870
Ricardo U. Macías-Rodríguez1, Aldo Torre-Delgadillo2,
Autor para correspondencia
detoal@yahoo.com

Address for correspondence:
1 Internal Medicine Fellow. Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”
2 Gastroenterology Department. Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”
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Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease that usually affects middle-aged women. The cause of PBC remains unknown, although genetic and immunologic factors appear to play a role. Many patients are asymptomatic at the time of diagnosis. The symptoms and signs of cholestasis develop as the disease progresses. At the physical examination the findings may vary and depend on the stage of the disease. Hypercholesterolemia is present in 50% of the patients and the xanthelasma and xanthomata correlate with it. Xanthelasmas are more common than xanthomata, but this findings are unnusual. Less than 5% of patients will eventually develop xanthomata (xanthomata striatum palmare), and are found on the palms of the hands and soles of the feet, over extensor surfaces of the elbows and knees, in tendons of the ankles and wrists, and on buttocks.

References
[1.]
Kaplan M.M..
Primary biliary cirrhosis.
N Engl J Med, 335 (1996), pp. 1570-1580
[2.]
Alastair D.B..
Primary biliary cirrhosis and other ductopenic diseases.
Clin Liver Dis, 6 (2002), pp. 363-380
Copyright © 2006. Fundación Clínica Médica Sur, A.C.
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