Información del artículo
Abstract
The complexity of the tissues and the healing process of the periodontal wound turn the development of therapies for the predictable regeneration of functional periodontal tissues, a challenging exercise. In the last decades, the guided tissue regeneration (GTR) emerged as a strategy to drive the innate regenerative properties of the tissues involved in the periodontal apparatus (gingiva, tooth root, periodontal ligament and alveolar bone). GTR therapies have shown that the use of membrane barriers that are occlusive for gingival cell migration and that provide wound stability and space provision for the first intentional repair promoted by cells originated from periodontal tissues can partially restore the primitive anatomy and function of the periodontium. This paper describes examples of the variety of non-degradable and degradable membrane barriers developed for GTR approaches. During the last 20 years, the research has evolved to develop GTR barriers that avoid the recurrent problems related with the early membrane exposure and the recurrent infections. Furthermore, the association of the GTR to tissue engineering principles, such as the inclusion of biochemical cues and new architectures as well as the association with stem cells of different niches, has given rise to new materials with improved properties and biological performance.
Keywords:
guided tissue regeneration
guided bone regeneration
biodegradable/non-biodegradable membranes
periodontal wound healing
periodontal defects.
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References
[1]
F.M. Chen, Y. Jin.
Tissue Eng Part B Rev., 16 (2010), pp. 2
[2]
H.L. Wang, M. Modarressi, J.H. Fu.
Periodontol 2000., 59 (2012), pp. 1
[3]
C. Susin, U.M.E. Wikesjö.
Periodontol 2000., 62 (2013), pp. 1
[4]
G. Polimeni, A.V. Xiropaidis, U.M. Wikesjo.
Periodontol 2000, 41 (2006),
[5]
A.H. Melcher, C.A. McCulloch, T. Cheong, E. Nemeth, A. Shiga.
J Periodontal Res., 22 (1987), pp. 3
[6]
T. Karring, S. Nyman, J. Gottlow, L. Laurell.
Periodontol 2000, 1 (1993),
[7]
D. Buser, K. Warrer, T. Karring.
J Periodontol, 61 (1990), pp. 9
[8]
J. Gottlow, S. Nyman, T. Karring, J. Lindhe.
J Clin Periodontol., 11 (1984), pp. 8
[9]
J. Gottlow, S. Nyman, J. Lindhe, T. Karring, J. Wennstrom.
J Clin Periodontol., 13 (1986), pp. 6
[10]
R.G. Caffesse, W. Becker.
Dent Clin North Am., 35 (1991), pp. 3
[11]
R. Hardwick, B.K. Hayes, C. Flynn.
J Periodontol, 66 (1995), pp. 6
[12]
T.V. Scantlebury.
J Periodontol, 64 (1993), pp. 11s
[13]
H. Tal, O. Moses, A. Kozlovsky, C. Nemcovsky, in: H. Tal (Eds.), Bone Regeneration, InTech, 2012, pp. 112-137.
[14]
U.M. Wikesjo, W.H. Lim, R.C. Thomson, W.R. Hardwick.
J Clin Periodontol., 30 (2003), pp. 7
[15]
W.H. Hiatt, R.E. Stallard, E.D. Butler, B. Badgett.
J Periodontol, 39 (1968), pp. 1
[16]
Y. Zhang, X. Zhang, B. Shi, R.J. Miron.
Ann Maxillofac Surg., 1 (2013), pp. 1
[17]
J.M. Carbonell, I.S. Martin, A. Santos, A. Pujol, J.D. Sanz-Moliner, J. Nart.
Int J Oral Maxillofac Surg., 43 (2014), pp. 1
[18]
H.U. Toygar, E. Guzeldemir, U. Cilasun, D. Akkor, N. Arpak.
J Biomed Mater Res B Appl Biomater., 91 (2009), pp. 2
[19]
D.K. Christensen, I.K. Karoussis, A. Joss, C.H. Hammerle, N.P. Lang.
Clin Oral Implants Res., 14 (2003), pp. 6
[20]
N.U. Zitzmann, R. Naef, P. Scharer.
Int J Oral Maxillofac Implants., 12 (1997), pp. 6
[21]
V. Lekovic, E.B. Kenney, M. Weinlaender, T. Han, P. Klokkevold, M. Nedic, M. Orsini.
J Periodontol, 68 (1997), pp. 6
[22]
H.A. Marouf, H.M. El-Guindi.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod., 89 (2000), pp. 2
[23]
B.K. Bartee.
Implant Dent, 4 (1995), pp. 1
[25]
M.N. Sela, D. Steinberg, A. Klinger, A.A. Krausz, D. Kohavi.
Clin Oral Implants Res., 10 (1999), pp. 6
[26]
A.S. Monteiro, L.G. Macedo, N.L. Macedo, I. Balducci.
Med Oral Patol Oral Cir Bucal., 15 (2010), pp. 2
[27]
N. Donos, L. Kostopoulos, T. Karring.
Clin Oral Implants Res., 13 (2002), pp. 2
[28]
P.J. Louis, R. Gutta, N. Said-Al-Naief, A.A. Bartolucci.
J Oral Maxillofac Surg., 66 (2008), pp. 2
[29]
A. Aurer, K. Jorgic-Srdjak.
Acta Stomatol Croat., 39 (2005), pp. 1
[30]
D. Rothamel, F. Schwarz, M. Sager, M. Herten, A. Sculean, J. Becker.
Clin Oral Implants Res., 16 (2005), pp. 3
[31]
T. Hockers, D. Abensur, P. Valentini, R. Legrand, C.H.F. Hämmerle.
Clin Oral Implants Res., 10 (1999), pp. 6
[32]
G. Zellin, A. Gritli-linde, A. Linde.
Biomaterials, 16 (1995), pp. 8
[33]
S. Pitaru, H. Tal, M. Soldinger, A. Grosskopf, M. Noff.
J Periodontol, 59 (1988), pp. 6
[34]
M. Minabe, T. Kodama, T. Kogou, T. Tamura, T. Hori, Y. Watanabe, T. Miyata.
J Periodontol, 60 (1989), pp. 1
[35]
T. Kodama, M. Minabe, T. Hori, Y. Watanabe.
J Periodontol, 60 (1989), pp. 4
[36]
D.M. Verissimo, R.F. Leitao, R.A. Ribeiro, S.D. Figueiro, A.S. Sombra, J.C. Goes, G.A. Brito.
Acta Biomater, 6 (2010), pp. 10
[37]
D. Rothamel, F. Schwarz, A. Sculean, M. Herten, W. Scherbaum, J. Becker.
Clin Oral Implants Res., 15 (2004), pp. 4
[38]
H. Petite, V. Frei, A. Huc, D. Herbage.
J Biomed Mater Res., 28 (1994), pp. 2
[39]
T. Takata, H.l. Wang, M. Miyauchi.
J Periodontal Res., 36 (2001), pp. 5
[40]
T. Takata, H.L. Wang, M. Miyauchi.
Clin Oral Implants Res., 12 (2001), pp. 4
[41]
E.J. Lee, S.H. Jun, H.E. Kim, Y.H. Koh.
J Biomed Mater Res A., 100 (2012), pp. 4
[42]
E.J. Lee, S.H. Teng, T.S. Jang, P. Wang, S.W. Yook, H.E. Kim, Y.H. Koh.
Acta Biomater, 6 (2010), pp. 9
[43]
J.F. Requicha, T. Moura, I.B. Leonor, T. Martins, F. Munoz, R.L. Reis, M.E. Gomes, C.A. Viegas.
J Orthop Res., 32 (2014), pp. 7
[44]
A.C. van Leeuwen, J.J. Huddleston Slater, P.F. Gielkens, J.R. de Jong, D.W. Grijpma, R.R. Bos.
Acta Biomater, 8 (2012), pp. 4
[45]
S.M. Kuo, S.J. Chang, G. Cheng-Chie Niu, C.-W. Lan, W.T. Cheng, C.Z. Yang.
J Appl Polym Sci., 112 (2009), pp. 5
[46]
J. Mota, N. Yu, S.G. Caridade, G.M. Luz, M.E. Gomes, R.L. Reis, J.A. Jansen, X.F. Walboomers, J.F. Mano.
Acta Biomater, 8 (2012), pp. 11
[47]
H. Hong, J. Wei, C. Liu.
Composites Part B, 38 (2007), pp. 3
[48]
A.F. Fraga, E.d.A. Filho, E.C.d.S. Rigo, A.O. Boschi.
Appl Surf Sci., 257 (2011), pp. 9
[49]
A.I. Leal, S.G. Caridade, J. Ma, N. Yu, M.E. Gomes, R.L. Reis, J.A. Jansen, X.F. Walboomers, J.F. Mano.
Dent Mater, 29 (2013), pp. 4
[50]
K. Fujihara, M. Kotaki, S. Ramakrishna.
Biomaterials, 26 (2005), pp. 19
[51]
K. Ishikawa, Y. Ueyama, T. Mano, T. Koyama, K. Suzuki, T. Matsumura.
J Biomed Mater Res A., 47 (1999), pp. 2
[52]
S.V. Madihally, H.W. Matthew.
Biomaterials, 20 (1999), pp. 12
[53]
P.R. Klokkevold, L. Vandemark, E.B. Kenney, G.W. Bernard.
J Periodontol, 67 (1996), pp. 11
[54]
S. Ming Kuo, S. Jen Chang, Y. Ting Hsu, T. Wei Chen.
Conf Proc IEEE Eng Med Biol Soc., 5 (2005),
[55]
T.W. Chen, S.J. Chang, G.C.-C. Niu, Y.T. Hsu, S.M. Kuo.
J Appl Polym Sci., 102 (2006), pp. 5
[56]
V. Gassling, T. Douglas, P.H. Warnke, Y. Acil, J. Wiltfang, S.T. Becker.
Clin Oral Implants Res., 21 (2010), pp. 5
[57]
P. Babo, V.E. Santo, A.R.C. Duarte, C. Correia, M.H.G. Costa, J.F. Mano, R.L. Reis, M.E. Gomes.
Inflamm Regen, 34 (2014), pp. 1
[58]
J. Choukroun, A. Diss, A. Simonpieri, M.O. Girard, C. Schoeffler, S.L. Dohan, A.J. Dohan, J. Mouhyi, D.M. Dohan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod., 101 (2006), pp. 3
[59]
M. Matsui, Y. Tabata.
Acta Biomater, 8 (2012), pp. 5
[60]
G. Mabilleau, E. Aguado, I.C. Stancu, C. Cincu, M.F. Basle, D. Chappard.
Biomaterials, 29 (2008), pp. 11
[61]
K.A. Athanasiou, G.G. Niederauer, C.M. Agrawal.
Biomaterials, 17 (1996), pp. 2
[62]
A. Stavropoulos, N. Mardas, F. Herrero, T. Karring.
J Clin Periodontol., 31 (2004), pp. 11
[63]
Y. Kang, Y. Yao, G. Yin, Z. Huang, X. Liao, X. Xu, G. Zhao.
Med Eng Phys., 31 (2009), pp. 5
[64]
J.F. Requicha, C.A. Viegas, F. Munoz, J.M. Azevedo, I.B. Leonor, R.L. Reis, M.E. Gomes.
Tissue Eng Part A., 20 (2014), pp. 17-18
[65]
A. Piattelli, A. Scarano, P. Russo, S. Matarasso.
Biomaterials, 17 (1996), pp. 8
[66]
H.D. Barber, J. Lignelli, B.M. Smith, B.K. Bartee.
J Oral Maxillofac Surg., 65 (2007), pp. 4
[67]
T. Takata, M. Miyauchi, H.l. Wang.
Clinical Oral Implants Research., 12 (2001), pp. 4
[68]
Y.K. Kim, S.G. Kim, S.C. Lim, H.J. Lee, P.Y. Yun.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod., 109 (2010), pp. 6
[69]
M.N. Sela, D. Kohavi, E. Krausz, D. Steinberg, G. Rosen.
Clin Oral Implants Res., 14 (2003), pp. 3
[70]
S. Liao, W. Wang, M. Uo, S. Ohkawa, T. Akasaka, K. Tamura, F. Cui, F. Watari.
Biomaterials, 26 (2005), pp. 36
[71]
S. Chen, Y. Hao, W. Cui, J. Chang, Y. Zhou.
J Mater Sci., 48 (2013), pp. 19
[72]
S.-C. Lim, M.-J. Lee, H.-H. Yeo.
Pathol Int, 50 (2000), pp. 8
[73]
H.l. Wang, M. Miyauchi, T. Takata.
J Periodontal Res., 37 (2002), pp. 5
[74]
Q. Cheng, K. Rutledge, E. Jabbarzadeh.
Ann Biomed Eng., 41 (2013), pp. 5
[75]
Z.-G. Zhang, Z.-H. Li, X.-Z. Mao, W.-C. Wang.
Cytotechnology, 63 (2011), pp. 5
[76]
C.J. Frandsen, K. Noh, K.S. Brammer, G. Johnston, S. Jin.
Mater Sci Eng C Mater Biol Appl., 33 (2013), pp. 5
[77]
J. Behring, R. Junker, X.F. Walboomers, B. Chessnut, J.A. Jansen.
Odontology, 96 (2008), pp. 1
[78]
E. Lamers, J. te Riet, M. Domanski, R. Luttge, C.G. Figdor, J.G. Gardeniers, X.F. Walboomers, J.A. Jansen.
Eur Cell Mater., 23 (2012),
[79]
M.J. Dalby, N. Gadegaard, R. Tare, A. Andar, M.O. Riehle, P. Herzyk, C.D.W. Wilkinson, R.O.C. Oreffo.
Nat Mater, 6 (2007), pp. 12
[80]
E. Lamers, R. van Horssen, J. te Riet, F.C. van Delft, R. Luttge, X.F. Walboomers, J.A. Jansen.
Eur Cell Mater., 20 (2010),
[81]
S. Srinivasan, R. Jayasree, K.P. Chennazhi, S.V. Nair, R. Jayakumar.
Carbohydrate Polymers, 87 (2012), pp. 1
[82]
F.Z. Mei, J. Yang, X. Ouyang, X. Zhang, S. Hu, X. Ma, Q. Lu, J. Ryu, S.X. Deng.
Biomacromolecules, 8 (2007),
[83]
V.E. Santo, M.E. Gomes, J.F. Mano, R.L. Reis.
J Tissue Eng Regen Med. 6 Suppl 3, (2012),
[84]
P.A. Norowski.
J Biomater Nanobiotechnol., 03 (2012), pp. 04
[85]
I. Ishikawa, T. Iwata, K. Washio, T. Okano, T. Nagasawa, K. Iwasaki, T. Ando.
Periodontol 2000., 51 (2009), pp. 1
[86]
T. Iwata, K. Washio, T. Yoshida, I. Ishikawa, T. Ando, M. Yamato, T. Okano.
J Tissue Eng Regen Med., (2013),
[87]
T. Iwata, M. Yamato, H. Tsuchioka, R. Takagi, S. Mukobata, K. Washio, T. Okano, I. Ishikawa.
Biomaterials, 30 (2009), pp. 14
[88]
J.F. Requicha, C.A. Viegas, F. Munoz, R.L. Reis, M.E. Gomes.
Anat Rec (Hoboken)., 297 (2014), pp. 1
