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Inicio Cirugía Española Función paratiroidea en el autotrasplante paratiroideo subcutáneo preesternal ...
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Vol. 76. Núm. 1.
Páginas 29-34 (julio 2004)
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Vol. 76. Núm. 1.
Páginas 29-34 (julio 2004)
Acceso a texto completo
Función paratiroidea en el autotrasplante paratiroideo subcutáneo preesternal en el hiperparatiroidismo secundario
Parathyroid function in presternal subcutaneous parathyroid autotransplantation in secondary hyperparathyroidism
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4984
Miguel Echeniquea,1
Autor para correspondencia
gepecelm@sc.ehu.es

Correspondencia: Miguel Echenique Elizondo. Departamento de Cirugía. Universidad del País Vasco. Unidad Docente de Medicina de San Sebastián. Paseo Dr. Beguiristain, 105. 20014 San Sebastián. España.
, José Antonio Amondarainb, Fernando Vidaurc
a Departamento de Cirugía. Universidad del País Vasco. San Sebastián. Guipúzcoa
b Departamento de Cirugía. Hospital Donostia. San Sebastián. Guipúzcoa
c Servicio de Nefrología. Hospital Donostia. San Sebastián. Guipúzcoa. España
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Información del artículo
Resumen
Bibliografía
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Estadísticas
Resumen
Introducción

Se ha estudiado la función del tejido paratiroideo trasplantado subcutáneamente.

Pacientes y método

Se ha estudiado a 13 pacientes sobre una población en diálisis total de 187 (6,95%) pacientes. Se realizó paratiroidectomía total y autotrasplante subcutáneo preesternal.

Resultados

Descendió el valor de hormona paratiroidea a las 24 h en todos los casos. Se observan concentraciones valorables de hormona paratiroidea a partir de la quinta semana postransplante en todos los casos.

Conclusiones

El trasplante paratiroideo subcutáneo preesternal es una alternativa válida y funcional en el tratamiento del hiperparatiroidismo secundario.

Palabras clave:
Hiperparatiroidismo secundario
Paratiroides
Trasplante
Introduction

To study the function of subcutaneously transplanted parathyroid tissue.

Patients and method

Of 187 patients undergoing hemodialysis, 13 patients (6.95%) were studied. Total parathyroidectomy with presternal subcutaneous autotransplantation was performed.

Results

In all patients, PTH levels at 24 hours were decreased. From the fifth week after transplantation PTH levels were clearly detectable in all patients.

Conclusions

Presternal subcutaneous parathyroid transplantation is a valid and functional alternative in the treatment of secondary hyperparathyroidism.

Key words:
Secondary hyperparathyroidism
Parathyroid
Transplantation
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Bibliografía
[1.]
E. Slatopolsky, J.A. Delmez.
Pathogenesis of secondary hyperpatathyroidism.
Am J Kidney Dis, 23 (1994), pp. 229-236
[2.]
A.M. Parfitt.
The hyperparathyroidism of chronic renal failure: a disorder of growth.
Kidney Inte, 52 (1997), pp. 3-9
[3.]
Y. Tominaga, Y. Tanaka, T. Sato Nagasaka, H. Tagaki.
Histopathology, pathophysiology and indications for surgical treatment of renal hyperparathyroidism.
Sem Surg Oncol, 13 (1997), pp. 78-86
[4.]
M. Fuguakwa, K. Kurokawa.
Pathogenesis and medical treatment of secondary hyperparathyroidism.
Sem Surg Oncol, 13 (1997), pp. 73-77
[5.]
S.A. Wells, J.C. Gunnells, J.D. Shelburne, A.B. Schneider, L.M. Sherwood.
Transplantation of parathyroid glands in man: clinical indications and results.
Surgery, 78 (1975), pp. 34-44
[6.]
E.R. Gagne, P. Urena, S. Leite-Silva, J. Zingraff, A. Chevalier, E. Sarfati, et al.
Short- and long-term efficacy of total parathyroidectomy with immediate autografting compared with subtotal parathyroidectomy in hemodialysis patients.
J Am Soc Nephrol, 3 (1992), pp. 1008-1017
[7.]
S. Ockert, F. Willeke, A. Richter, J. Jonescheit, P. Schnuelle, F. Van der Woude, et al.
Total parathyroidectomy without autotransplantation as a standard procedure in the treatment of secondary hyperparathyroidism.
Langenbecks Arch Surg, 387 (2002), pp. 204-209
[8.]
J.M. Monchik, C. Bendinelli, M.A. Passero, K.K. Roggin.
Subcutaneous forearm transplantation of autologous parathyroid tissue in patients with renal hyperparathyroidism.
Surgery, 126 (1999), pp. 1152-1158
[9.]
F.F. Chou, H.M. Chan, T.J. Huang, C.H. Lee, K.T. Hsu.
Autotransplantation of parathyroid glands into subcutaneous forearm tissue for renal hyperparathyroidism.
Surgery, 124 (1998), pp. 1-5
[10.]
P. Kinnaert, I. Salmon, C. Decoster-Gervy, P. Bergman, L. Hooghe, L. De Pauw, et al.
Total parathyroidectomy and presternal subcutaneous implantation of parathyroid tissue for renal hyperparathyroidism.
Surg Gynecol Obstet, 176 (1993), pp. 135-138
[11.]
C. Dubost, T. Drueke, P.L. Jeaneau, J. Zingraff, J. Crosnier.
Secondary hyperparathyroidism: subtotal parathyroidectomy versus total parathyroidectomy with parathyroid autotransplantation.
Nouv Presse Med, 9 (1980), pp. 2709-2713
[12.]
F. Zaraca, S. Mazzaferro, M. Catarci, A. Saputelli, P. Alo, M. Carboni.
Prospective evaluation of total parathyroidectomy and autotransplantation for the treatment of secondary hyperparathyroidism.
Arch Surg, 134 (1999), pp. 68-72
[13.]
P. Kinnaert, I. Salmon, C. Decoster-Gervy, A. Vienne, L. De Pauw, L. Hooghe, et al.
Long-term results of subcutaneous parathyroid grafts in uremic patients.
Arch Surg, 135 (2000), pp. 186-190
[14.]
H. Hidai, T. Chiba, Y. Takagi, T. Mori, T. Taniguchi, T. Hyodo.
Percutaneous autotransplantation of parathyroid tissue into the forearm muscles.
Surg Today, 28 (1998), pp. 114-116
[15.]
K.A. Skinner, L. Zuckerbraun.
Recurrent secondary hyperparathyroidism. An argument for total parathyroidectomy.
Arch Surg, 131 (1996), pp. 724-727
[16.]
V. Donckier, C. Decoster-Gervy, P. Kinnaert.
Long-term results after surgical treatment of renal hyperparathyroidism when fewer than four glands are identified at operation.
J Am Coll Surg, 184 (1997), pp. 70-74
[17.]
G. Ackerstrom, J. Malmeus, R. Gergström.
Surgical anatomy of human parathyroid glands.
Surgery, 95 (1984), pp. 14-21
[18.]
O.J. Hines, H.E. Gordon.
Secondary hyperparathyroidism in a patient with eight parathyroid glands.
J Clin Endocrinol Metab, 83 (1998), pp. 2384-2386
[19.]
A. Kostakis, G. Vaiopoulos, K. Konstantopoulos, G. Zavos, I. Bocos, S. Sgouromalis.
Parathyroidectomy in the treatment of secondary hyperparathyroidism in chronic renal faliure.
Int Surg, 82 (1997), pp. 85-86
[20.]
M. Rothmund, P. Wagner.
Reoperations for recurrent and persistent secondary hyperparathyroidism.
Ann Surg, 207 (1988), pp. 310-314
[21.]
F.F. Chou, C.H. Lee, H.Y. Chen, J.B. Chen, K.T. Hsu, S.M. Sheen-Chen.
Persistent and recurrent hyperparathyroidism after total parathyroidectomy with autotransplantation.
Ann Surg, 235 (2002), pp. 99-104
[22.]
M. Kessler, J.M. Avila, E. Renoult, P. Mathieu.
Reoperation for secondary hyperparathyroidism in chronic renal faliure.
Transplant, 6 (1991), pp. 176-179
[23.]
H. Hampl, T. Steinmuller, U. Stabell, H.J. Klingenberg, N. Schnoy, P. Neuhaus.
Recurrent hyperparathyroidism after total parathyroidectomy and autotransplantation in patients with long-term hemodialysis.
Miner Electrolyte Metab, 17 (1991), pp. 256-260
[24.]
U. Frei, I. Klempa, M. Schneider, E.H. Scheuermann, K.M. Koch.
Tumorlike growth of parathyroid autografts in uraemic patients.
Proc Eur Dial Transplant Assoc, 18 (1981), pp. 548-555
[25.]
H. Ohta, T. Komibuchi, M. Nishimura, K. Nishimura, Y. Nagao, H. Watanabe, et al.
99mTc-MIBI accumulation in the parathyroid autograft in a patient with recurrent hyperparathyroidism.
Ann Nucl Med, 10 (1996), pp. 247-249
[26.]
D. Casanova, E. Sarfati, A. De Francisco, J.A. Amado, M. Arias, C. Dubost.
Secondary hyperparathyroidism: diagnosis and site of recurence.
World J Surg, 15 (1991), pp. 546-549
[27.]
P. Cattan, B. Halimi, K. Aidan, C. Billotey, C. Tamas, T.B. Drüeke, et al.
Reoperation for secondary uremic hyperparathyroidism: are technical difficulties influenced by inicial surgical procedure?.
Surgery, 127 (2000), pp. 562-565
[28.]
I. Adalet, T. Hawkins, F. Clark, R. Wilkinson.
Thalliumm-Technetiumsubstraction scintigraphy in secondary hiperparathyroidism.
Eur J Nucl Med, 21 (1994), pp. 509-513
[29.]
E. Martínez Pérez, F. Larrañaga, P.A. Serrano.
Utilidad de las diferentes técnicas de localización en el hiperparatiroidismo.
Cir Esp, 66 (1999), pp. 6168
[30.]
M. Piga, P. Bolasco, L. Satta, P. Altieri, G. Loi, A. Nicolosi, et al.
Double phase parathyroid technetium-99m-MIBI scintigraphy to identify functional autonomy in secondary hyperparathyroidism.
J Nucl Med, 37 (1996), pp. 565-569
[31.]
E. Hindie, P. Ureña, C. Jeanguillaume, D. Melliere, J.M. Berthelot, V. Menoyo-Calonge, et al.
Preoperative imaging of parathyroid glands with technetium-99m-labelled sestamibi and iodine-123 substraction scanning in secondary hyperparathyroidism.
Lancet, 353 (1999), pp. 2200-2204
[32.]
M.H. Thelen, T. Kuwert, H. Lerch, C. Witting, B. Winterberg, O. Schober.
Double-phase Tc-99m MIBI scintigraphy in secondary hyperparathyroidism relapsing after parathyroidectomy and removal of a parathyroid autograft.
Clin Nucl Med, 21 (1996), pp. 609-611
Copyright © 2004. Asociación Española de Cirujanos
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