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Vol. 85. Núm. 6.
Páginas 360-364 (junio 2009)
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Vol. 85. Núm. 6.
Páginas 360-364 (junio 2009)
Acceso a texto completo
Oesophageal endoscopic ultrasound in the accurate location of primary hyperparathyroidism (HPT)
Valor de la ecoendoscopia transesofágica en el diagnóstico de localización en el hiperparatiroidismo primario
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1544
Aitor de la Quintana Basarratea,
Autor para correspondencia
, Francisco Javier Díaz Aguirregoitiaa, Jesús Gil Sáncheza, Ángel Barturen Barrosob, Sonia Gaztambide Sáezc, Miguel Echenique Elizondod,1, Luis Perdigo Bilbaoe
a Servicio de Cirugía General B, Sección de Cirugía Endocrina, Hospital de Cruces, Barakaldo, Bizkaia, Spain
b Servicio de Digestivo, Hospital de Cruces, Barakaldo, Bizkaia, Spain
c Servicio de Endocrinología, Hospital de Cruces, Barakaldo, Bizkaia, Spain
d Catedrático de Cirugía, Universidad del País Vasco, Barakaldo, Bizkaia, Spain
e Servicio de Cirugía General B, Hospital de Cruces, Barakaldo, Bizkaia, Spain
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Abstract
Aim

Our aim was to estimate the usefulness of oesophageal endoscopic ultrasound in the accurate location of recurrent or persistent primary hyperparathyroidism (HPT).

Material and method

A total of 352 patients with primary hyperparathyroidism were operated on over the last 7 years. A preoperative parathyroid 99Tc-sestamibi gammagraphy and an intraoperative PTH determination were performed routinely. Only 5 patients (1.4%) had localization problems: 3 with persistent HPT after parathyroid extirpation, 1 recurrent HPT and 1 HPT after a right hemithyroidectomy. An oesophageal endoscopic ultrasound was carried out before any new exploratory neck surgery in order to find the definitive location.

Results

The endoscopic ultrasound showed a clear image of adenoma with an accurate location in 4 patients. No tumour was present in 1 patient. All 5 patients were operated on. The exact location was confirmed in the 4 patients with positive endoscopic ultrasound images. The fifth surgical exploration revealed a parathyreosis. All 5 patients had a favourable post-operative period, with no nerve lesions or morbidity associated with the endoscopic ultrasound.

Conclusions

Oesophageal endoscopic ultrasound is a very useful diagnostic tool in HPT patients with location problems, particularly in cases having anatomical changes due to previous surgery. It is a procedure that helps the surgeon to make a more selective and efficient exploration of parathyroid glands.

Keywords:
Oesophageal endoscopic ultrasound
Primary hyperparathyroidism
Persistent
Resumen
Objetivos

Considerar la utilidad de la ecoendoscopia trasesofágica en la localización del hiperparatiroidismo primario recidivado o persistente.

Material y método

Durante 7 años consecutivos, hemos intervenido a 352 pacientes con hiperparatiroidismo primario (HPP). Sistemáticamente se realiza gammagrafía paratiroidea con 99Tc-sestamibi preoperatorio y determinación intraoperatoria de paratirina. Sólo 5 (1,4%) pacientes han presentado problemas de localización: 3 por persistencia tras cirugía paratiroidea, 1 por recidiva y 1 por HPP con antecedente de hemitiroidectomía derecha. Antes de indicar una cervicotomía exploradora, se decide la realización de una ecoendoscopia trasesofágica para intentar una localización definitiva.

Resultados

La ecoendoscopia detecta una imagen clara de adenoma con localización precisa en 4 pacientes. Sólo en 1 paciente no se visualiza tumoración. Los 5 pacientes fueron intervenidos. Se confirmó la exactitud del diagnóstico en los 4 pacientes con visualización positiva. La exploración quirúrgica del quinto paciente resultó ser una paratireosis. Los 5 pacientes tuvieron un postoperatorio favorable, sin lesiones recurrenciales ni morbilidad asociada a la ecoendoscopia.

Conclusiones

La ecoendoscopia trasesofágica resulta muy útil en los hiperparatiroidismo que presenta dificultades para localizar la glándula patológica, especialmente en casos con alteración anatómica por cirugía previa. Así, ayuda a que el cirujano pueda explorar la zona sospechosa de forma más selectiva y más eficiente.

Palabras clave:
Ecoendoscopia transesofágica
Hiperparatiroidismo primario
Persistencia
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Prof Miguel Echenique Elizondo died before the publication of this article.

Based on communication presented in the National Meeting organized by the AEC in San Sebastian in November 2007.

Copyright © 2009. Asociación Española de Cirujanos
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