Información de la revista
Vol. 16. Núm. 1.
Páginas 29-37 (enero 2004)
Vol. 16. Núm. 1.
Páginas 29-37 (enero 2004)
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Papel de la mitocondria en el proceso de envejecimiento
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F. Cardellach1
, O. Miró
Autor para correspondencia
fcardell@clinic.ub.es
Correspondencia: Dr. F. Cardellach. Servicio de Medicina Interna General. Hospital Clínic. Villarroel, 170. 08036 Barcelona. España. Correo electrónico:
Correspondencia: Dr. F. Cardellach. Servicio de Medicina Interna General. Hospital Clínic. Villarroel, 170. 08036 Barcelona. España. Correo electrónico:
Laboratorio de Funcionalismo Mitocondrial. Grupo de Investigación Muscular. IDIBAPS. Servicio de Medicina Interna General
Hospital Clínic. Universidad de Barcelona. Barcelona. España
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Bibliografía
[1.]
M.K. Shigenaga, T.M. Hagen, B.N. Ames.
Oxidative damage and mitochondrial decay in aging.
Proc Natl Acad Sci USA, 91 (1994), pp. 10771-10778
[2.]
M.K. Shigenaga, B.N. Ames.
Oxidants and mitochondrial decay in aging.
Natural oxidants in human health and disease, Academic Press Inc, (1994),
[5.]
M. Ballester.
Antioxidantes, radicales libres y salud. Un enfoque químico-orgánico-físico.
Med Clin (Barc), 107 (1996), pp. 509-515
[6.]
J.A. Knight.
Free Radicals: Their history and current status in aging and disease.
Ann Clin Lab Sci, 28 (1998), pp. 331-346
[7.]
B. Halliwell, J.M.C. Gutteridge.
Oxygen toxicity, oxygen radicals, transition metals and disease.
Biochem J, 219 (1984), pp. 1-14
[8.]
C. Rice-Evans, K.R. Bruckdorfer.
Free radicals lipoproteins and cardiovascular dysfunction.
Mol Aspects Med, 13 (1992), pp. 1-111
[9.]
M. Degli Esposti.
Measuring mitochondrial reactive oxygen species.
Methods, 26 (2002), pp. 335-340
[10.]
G. Lenaz.
Role of mitochondria in oxidative stress and ageing.
Biochim Biophys Acta, 1366 (1998), pp. 53-67
[11.]
L.G.J. Nijtmans, M. Artal Sanz, L.A. Grivell, P.J. Coates.
The mitochondrial PBH complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease.
Cell Mol Life Sci, 59 (2002), pp. 143-155
[12.]
H.C. Lee, Y.H. Wei.
Role of mitochondria in human aging.
J Biomed Sci, 4 (1997), pp. 319-326
[13.]
T. Finkel, N. Holbrook.
Oxidants, oxidative stress and the biology of ageing.
Nature, 408 (2000), pp. 239-247
[14.]
G. Benzi, A. Moretti.
Age and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system.
Free Rad Biol Med, 19 (1995), pp. 77-101
[15.]
S. Papa, V.P. Skulachev.
Reactive oxygen species, mitochondria, apoptosis and aging.
Mol Cel Biochem, 174 (1997), pp. 305-319
[16.]
F. Cardellach, M.J. Martí, J. Fernández-Solá, C. Marín, J.D. Hoek, E. Tolosa, et al.
Mitochondrial respiratory chain activity in skeletal muscle from patients with Parkinson’s disease.
Neurology, 43 (1993), pp. 2258-2262
[17.]
A.H. Schapira, M. Gu, J.W. Taanman, S.J. Tabrizi, T. Seaton, M. Cleeter, et al.
Mitochondria in the etiology and pathogenesis of Parkinson’s disease.
Ann Neurol, 44 (1998), pp. S89-S98
[18.]
P.F. Chinnery, D.C. Samuels, J. Elson, D.M. Turnbull.
Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?.
Lancet, 360 (2002), pp. 1323-1325
[19.]
A.P. Wickens.
Ageing and the free radical theory.
Resp Physiol, 128 (2001), pp. 379-391
[20.]
V.P. Skulachev.
Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell.
FEBS Lett, 397 (1996), pp. 7-10
[23.]
P. Corbisier, J. Remacle.
Involvement of mitochondria in cell degeneration.
Eur J Cell Biol, 51 (1990), pp. 173-182
[24.]
I. Trounce, E. Byrne, S. Marzuki.
Decline in skeletal muscle mitochondrial respiration chain function: possible factor in ageing.
Lancet, 1 (1989), pp. 637-639
[25.]
D. Boffoli, S.C. Scacco, R. Vergari, G. Solarino, G. Santacroce, S. Papa.
Decline with age of the respiratory chain activity in human skeletal muscle.
Biochim Biophys Acta, 1226 (1994), pp. 73-82
[26.]
F. Cardellach, J. Galofré, R. Cussó, A. Urbano-Márquez.
Decline in skeletal muscle mitochondrial respiration chain function with ageing.
Lancet, 2 (1989), pp. 44-45
[27.]
D.J. Taylor, G.J. Kemp, C.H. Thompson, G.K. Radda.
Ageing: effects on oxidative function of skeletal muscle in vivo.
Mol Cel Biochem, 174 (1997), pp. 321-324
[28.]
J.H. Kim, G. Woldgiorgis, C.E. Elson, E. Shargo.
Age-related changes in respiration coupled to phosphorylation. I. Hepatic mitochondria.
Mech Ageing Dev, 46 (1988), pp. 263-277
[29.]
T.C. Yen, K.L. Chen, S.H. King, S.H. Weh, Y.H. Wei.
Liver mitochondrial respiratory functions decline with age.
Biochem Biophys Res Commun, 165 (1989), pp. 994-1003
[30.]
T.C. Yen, Y.S. Chen, K.L. King, S.H. Yeh, Y.H. Wei.
Liver mitochondrial respiratory functions decline with age.
Biochem Biophys Res Commun, 165 (1989), pp. 994-1003
[31.]
A. Barrientos, J. Casademont, A. Rötig, O. Miró, A. Urbano-Márquez, P. Rustin, et al.
Absence of relationship between the level of electron transport chain activities and ageing in skeletal muscle.
Biochem Biophys Res Commun, 229 (1996), pp. 536-539
[32.]
O. Miró, J.R. Alonso, D. Jarreta, J. Casademont, A. Urbano-Márquez, F. Cardellach.
Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes.
Carcinogenesis, 20 (1999), pp. 1331-1336
[33.]
D. Chreien, J. Gallego, A. Barrientos, J. Casademont, F. Cardellach, A. Munnich, et al.
Biochemical parameters for the diagnosis of mitochondrial respiratory chain deficiency in humans, and their lack of age-related changes.
Biochem J, 329 (1998), pp. 249-254
[34.]
A. Barrientos, J. Casademont, P. Rustin, F. Cardellach.
Biochemical aspects of aging of skeletal muscle injuries.
[35.]
O. Miró, J. Casademont, E. Casals, M. Perea, A. Urbano-Márquez, P. Rustin, et al.
Aging is associated with increased lipid peroxidation in human hearts, but not with mitochondrial respiratory chain enzyme defects.
Cardiovasc Res, 47 (2000), pp. 624-631
[36.]
E.J. Brierley, M.A. Johnson, O.F.W. James, D.M. Turnbull.
Mitochondrial involvement in the ageing process. Facts and controversies.
Mol Cel Biochem, 174 (1997), pp. 325-328
[38.]
J. Miquel.
An integrated theory of aging as the result of mitochondrial- DNA mutation in differentiated cells.
Arch Gerontol Geriatr, 12 (1991), pp. 99-117
[39.]
J.M. Cooper, V.M. Mann, A.H.V. Schapira.
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing.
J Neurol Sci, 113 (1992), pp. 91-98
[40.]
G.A. Cortopassi, N. Arnheim.
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
Nucleic Acids Res, 18 (1990), pp. 6927-6933
[41.]
T.C. Yen, J.H. Su, K.L. King, Y.H. Wei.
Age associated 5 kb deletion in human liver.
Biochem Biophys Res Commun, 178 (1991), pp. 124-131
[42.]
G.A. Cortopassi, D. Shibata, N.W. Soong, N. Arnheim.
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.
Proc Nat Acad Sci USA, 89 (1992), pp. 7370-7374
[43.]
M. Corral-Debrinski, T. Horton, M. Lott, J. Shoffner, M. Beal, D. Wallace.
Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age.
Nat Genet, 2 (1992), pp. 324-329
[44.]
K. Hattori, M. Tanaka, Sugiyama, et al.
Age-dependent increase in deleted mitochondrial DNA in the human heart: possible contributory factor to presbycardia.
Am Heart J, 121 (1991), pp. 1735-1742
[45.]
M. Katayama, M. Tanaka, H. Yamamoto, T. Ohbayashi, Y. Nimura, T. Ozawa.
Deleted mitochondrial DNA in skeletal muscle of aged individuals.
Biochem International, 25 (1991), pp. 47-56
[46.]
C.H. Zhang, A.W. Linnane, P. Nagley.
Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans.
Biochem Biophys Res Commun, 2 (1993), pp. 1104-1110
[47.]
A. Barrientos, J. Casademont, F. Cardellach, E. Ardite, X. Estivill, A. Urbano-Márquez, et al.
Qualitative and quantitative changes in skeletal muscle mtDNA and expression of mitochondrial-encoded genes in the human aging process.
Biochem Mol Med, 62 (1997), pp. 165-171
[48.]
A. Barrientos, J. Casademont, F. Cardellach, X. Estivill, A. Urbano-Márquez, V. Nunes.
Reduced steady-state levels of mitochondrial RNA increased mitochondrial DNA amount in human brain with aging.
Mol Brain Res, 52 (1997), pp. 284-289
[49.]
M.N. Gadaleta, V. Petruzzella, M. Renis, F. Fracasso, P. Cantatore.
Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of acetyl-L-carnitine.
Eur J Biochem, 187 (1990), pp. 501-506
[50.]
M.N. Gadaleta, G. Rainaldi, A.M.S. Lezza, F. Milella, F. Fracasso, P. Cantatore.
Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats.
Mut Res, (1992), pp. 181-193
[51.]
J. Casademont, J.M. Grau, O. Miró, B. Coll-Vinent, F. Cardellach, J. Montoya, et al.
Relación entre anomalías mitocondriales musculares y procesos inflamatorios y envejecimiento.
Neurología, 8 (1993), pp. 384-385
[52.]
J.M. Grau, J. Casademont, B. Coll-Vinent, O. Miró, F. Cardellach, A. Urbano-Márquez.
Muscle mitochondrial abnormalities.
Ageing, inflammation or both? Clin Neuropathol, 13 (1994), pp. 341
[53.]
J.M. Grau, J. Casademont, F. Cardellach, J. Fernández-Solá.
Aging and muscle mitochondrial abnormalities.
Ann Neurol, 38 (1995), pp. 274-275
[54.]
J.A. Knight.
Free radicals, antioxidants, aging and disease, American Association for Clinical Chemistry Inc, (1999),
[55.]
S. Raha, B.H. Robinson.
Mitochondria, oxygen free radicals, disease and ageing.
Trends Biochem Sci, 25 (2000), pp. 502-508
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