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Inicio Clínica e Investigación en Ginecología y Obstetricia Tratamiento hormonal sustitutivo de la menopausia y mortalidad
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Vol. 31. Núm. 3.
Páginas 85-92 (enero 2004)
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Vol. 31. Núm. 3.
Páginas 85-92 (enero 2004)
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Tratamiento hormonal sustitutivo de la menopausia y mortalidad
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3883
J. López-Olmos
Unidad de Menopausia. Servicio de Ginecología. Hospital Arnau de Vilanova. Valencia. España.
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Resumen

Presentamos 5 casos de mortalidad con THS (0,61%) en una serie personal de 810 mujeres tratadas durante 8 años.

La edad media fue 58,2 años (rango,52-68 años). La edad media a la menopausia fue de 47,6 años (ran-go,43-54 años). El tiempo medio de THS fue de 6,8años (rango 4-9 años).

Los procesos y su causa de muerte fueron:una insuficiencia respiratoria por pancreatitis aguda necrohemorrágica; un cáncer de estómago con metástasis múltiples; un cáncer de pulmón con metástasis óseas; una pancitopenia grave y shock secundarios a metotrexato,y un cáncer de mama con metástasis múltiples. Este último caso es el único que podemos relacionar con el THS.

Revisamos la mortalidad con THS,y en particular su riesgo en el cáncer de mama.

Abstract

We present 5 cases of mortality with HRT (0.61%) in a personal series of 810 women treated over 8 years.

The mean age was 58.2 years (range, 52-68). The mean age at the menopause was 47.6 years (range, 43-54). The mean duration of treatment was (6.8) years (range, 4-9). The causes of death were: acute respiratory failure following acute necrohaemorrhagic pancreatitis; stomach cancer with multiple metastases; lung cancer with bone metesteses; severe pancytopenia and shock secondary to Metotrexate treatment; and a breast cancer with multiple metasteses. The last case is the only one that we can relate to HRT. We reviewed mortality with HRT particularly related to breast cancer risk.

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Copyright © 2004. Elsevier España, S.L.. Todos los derechos reservados
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