We describe the clinical features of a malignant Phyllodes tumour in a 41 year old patient, which me-tastasised in the soft tissue of the thigh. We correlate these findings with the histo-pathological criteria associated with the clinical course and metastatic behaviour of this tumour. Stromal overgrowth is the most important criteria for predicting the metastatic behaviour of a malignant Phyllodes tumour.
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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The extent of surgery and prognosis with <span class="elsevierStyleItalic">phyllodes</span> tumor of the breast" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Ch Zissis" 1 => "N Apostolikas" 2 => "A Konstantinidou" 3 => "J Griniatsos" 4 => "PP. Vassilopoulos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Breast Cancer Res Treat" "fecha" => "1998" "volumen" => "48" "paginaInicial" => "205" "paginaFinal" => "210" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9598867" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metastatic cystosarcoma phyllodes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E Rainville" 1 => "KW. Hanley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "A case report. Acta cytol" "fecha" => "1993" "volumen" => "37" "paginaInicial" => "555" "paginaFinal" => "558" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histological typing of breast tumors" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "WHO." "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Tumori" "fecha" => "1982" "volumen" => "68" "paginaInicial" => "181" "paginaFinal" => "198" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6291202" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The treatment and prognosis of patients with <span class="elsevierStyleItalic">phyllodes</span> tumor of the breast" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M Reinfuss" 1 => "J Mitus" 2 => "K Duda" 3 => "A Stelmach" 4 => "J Rys" 5 => "K. Smolak" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "An analysis of 170 cases. Cancer" "fecha" => "1996" "volumen" => "77" "paginaInicial" => "910" "paginaFinal" => "916" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prognostic factors in cystosarcoma phyllodes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G Cohn-Cedermark" 1 => "LE Rutqvist" 2 => "I Rosendahl" 3 => "C. Silf-verswärd" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "A clinico-pathologic study of 77 patients. Cancer" "fecha" => "1991" "volumen" => "68" "paginaInicial" => "2017" "paginaFinal" => "2022" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Malignant cystosarcoma <span class="elsevierStyleItalic">phyllodes</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "ED Staren" 1 => "G Lynch" 2 => "C Boyle" 3 => "TR Witt" 4 => "SD. Bines" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am Surg" "fecha" => "1994" "volumen" => "60" "paginaInicial" => "583" "paginaFinal" => "585" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8030812" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical management of <span class="elsevierStyleItalic">phyllodes</span> tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "AA Mangi" 1 => "BL Smith" 2 => "MA Gadd" 3 => "KK Tanabe" 4 => "MJ Ott" 5 => "WW. Souba" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Surg" "fecha" => "1999" "volumen" => "134" "paginaInicial" => "487" "paginaFinal" => "493" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10323420" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ifosfamide is an active drug for chemotherapy of metastatic cystosarcoma <span class="elsevierStyleItalic">phyllodes</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "RE Hawwkins" 1 => "JB Schofield" 2 => "E Wiltshaw" 3 => "C Fisher" 4 => "JA. Mc-Kinna" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1992" "volumen" => "69" "paginaInicial" => "2271" "paginaFinal" => "2275" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1314127" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary treatment of cystosarcoma <span class="elsevierStyleItalic">phyllodes</span> of the breast" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "AW Chaney" 1 => "A Pollack" 2 => "MD Mcneese" 3 => "GK Zagars" 4 => "PW Pisters" 5 => "RE Pollock" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "2000" "volumen" => "89" "paginaInicial" => "1502" "paginaFinal" => "1511" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11013364" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The clinical and histologic criteria that predict metastases from cystosarcoma <span class="elsevierStyleItalic">phyllodes</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "RE Hawkins" 1 => "JB Schofield" 2 => "C Fisher" 3 => "E Wiltshaw" 4 => "JA. McKinna" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1992" "volumen" => "69" "paginaInicial" => "141" "paginaFinal" => "147" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1309302" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Factors leading to local recurrence or death after surgical resection of <span class="elsevierStyleItalic">phyllodes</span> tumours of the breast" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "WK De Roos" 1 => "P Kaye" 2 => "DM. Dent" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Sur" "fecha" => "1999" "volumen" => "86" "paginaInicial" => "396" "paginaFinal" => "399" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sarcoma and cysto-sarcoma <span class="elsevierStyleItalic">phyllodes</span> tumors of the breast" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "GI McGregor" 1 => "MA Knowling" 2 => "FA. Este" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "A retrospective review of 58 cases. Am J Surg" "fecha" => "1994" "volumen" => "167" "paginaInicial" => "477" "paginaFinal" => "480" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Phyllodes</span> tumors of the breast: a review of 32 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "DP Geisler" 1 => "MJ Boyle" 2 => "KF Malnar" 3 => "JM McGee" 4 => "MC Nolen" 5 => "SM Fortner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am Surg" "fecha" => "2000" "volumen" => "66" "paginaInicial" => "360" "paginaFinal" => "366" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10776873" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Steroid receptors in cystosarcoma <span class="elsevierStyleItalic">phyllodes</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "MM Brentani" 1 => "MA Nagai" 2 => "CT Oshima" 3 => "MM Pacheco" 4 => "JC Goes" 5 => "LB. Lemos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer Detect Prev" "fecha" => "1982" "volumen" => "5" "paginaInicial" => "211" "paginaFinal" => "219" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6290062" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histologic features predict local recurrence after breast conserving therapy of <span class="elsevierStyleItalic">phyllodes</span> tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "RJ. Barth" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Breast Cancer Res Treat" "fecha" => "1999" "volumen" => "57" "paginaInicial" => "291" "paginaFinal" => "295" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10617306" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/0210573X/0000002900000005/v1_201307111158/S0210573X0277175X/v1_201307111158/es/main.assets" "Apartado" => array:4 [ "identificador" => "15120" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Casos clínicos" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/0210573X/0000002900000005/v1_201307111158/S0210573X0277175X/v1_201307111158/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210573X0277175X?idApp=UINPBA00004N" ]