covid
Buscar en
Endocrinología y Nutrición
Toda la web
Inicio Endocrinología y Nutrición Sistema de monitorización continua de glucosa: una nueva herramienta para mejor...
Información de la revista
Vol. 48. Núm. 9.
Páginas 266-271 (noviembre 2001)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 48. Núm. 9.
Páginas 266-271 (noviembre 2001)
Acceso a texto completo
Sistema de monitorización continua de glucosa: una nueva herramienta para mejorar el control metabólico de los pacientes diabéticos
Continous glucose monitoring system: a new tool to improve glycemic control of diabetic patients
Visitas
7618
A. Chico
Autor para correspondencia
28299acb@webcmb.comb.es

Correspondencia: Dra. A. Chico Servicio de Endocrinología. Fundación Sardà Farriol. P.° Bonanova 69, 6.a planta. 08017 Barcelona.
, M. Subirà, A. Novials
Servicio de Diabetología. Fundación Sardà Farriol. Barcelona
Este artículo ha recibido
Información del artículo

Recientemente se ha comercializado en España un nuevo sistema de monitorización continua de glucosa, que permite conocer de forma muy detallada el perfil de glucosa de los pacientes diabéticos durante las 24 h del día. Se trata de un sistema portátil de pequeño tamaño que el paciente lleva implantado un mínimo de 72 h y que se compone básicamente de un sensor que se inserta en el tejido subcutáneo del abdomen conectado a un monitor, que registra cada 5 min la concentración de glucosa del tejido intersticial. Los datos registrados son posteriormente visualizados y analizados en un ordenador mediante el software adecuado. Diferentes estudios han demostrado una excelente correlación entre los valores de glucosa determinados por el sensor y los de glucemia capilar y venosa. Asimismo, varios trabajos han demostrado la utilidad de la información suministrada por el sistema para iniciar o modificar el tratamiento de los pacientes y, en consecuencia, para mejorar su control metabólico.

En esta revisión se describen las características del sistema, su funcionamiento, la información que proporciona y la utilidad del mismo en diferentes situaciones.

Palabras clave:
Sensor de glucosa
Control metabólico

Recently, a new continous glucose monitoring system, that provides detailed information of the glucose pattern of diabetic patients during all the day, has been comercialised in our country. It is a small portable system that the patient has inserted during a period of 72 hours. It is basically composed of a sensor inserted in the subcutaneous tissue of the abdomen which is connected to a monitor recording glucose concentration of interstitial tissue every 5 minutes. The data recorded can be visualised and analysed on a computer with the appropiate software. Different studies have demonstrated an excellent correlation between glucose levels obtained by sensor and capillar and venous glucose levels. Additionally, some investigations have demonstrated that the data obtained by the system is useful to start or change patient therapy, and consequently, to improve metabolic control.

In this review, we describe the features of the system, how it works, the information that it provides and how it can be used in different situations.

Key words:
glucose sensor
Metabolic control
El Texto completo está disponible en PDF
Bibliografía
[1.]
DCCT Study Group.
The effect of intensive treatment of diabetes on the development and progression of long-term complications in IDDM.
N Engl J Med, 329 (1993), pp. 977-986
[2.]
UKPDS.
Intensive blood glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes.
Lancet, 352 (1998), pp. 837-853
[3.]
American Diabetes Association:.
Standars of medical care for patients with diabetes.
Diabetes Care, 21 (1998), pp. 1-198
[4.]
American Diabetes Association.
Self-monitoring of blood glucose (Consensus statement).
Diabetes Care, 19 (1996), pp. 562-566
[5.]
J.A. Tamada, N.J.V. Bohannon, R.O. Potts.
Measurement of blood glucose in diabetic subjects using non-invasive transdermal extraction.
Nature Med, 1 (1995), pp. 1198-1201
[6.]
M.J. Tierney, Y. Jayalakshmi, N.A. Parris, M.P. Reidy, C. Uhegbu, P. Vijayakumar.
Design of a biosensor for continuos, transdermal, glucose monitoring.
Clin Chem, 45 (1999), pp. 1678
[7.]
S.K. Garg, R.O. Potts, N.R. Ackerman, S. Fermi, J.A. Tamada, P.H. Chase.
Correlation of finger-stick blood glucose measurements with Gluco-Watch® biographer glucose results in young subjects with type 1 Diabetes.
Diabetes Care, 22 (1999), pp. 1708
[8.]
M.J. Tierney, J.A. Tamada, R.O. Potts, R.C. Eastman, K. Pitzer, N.R. Ackerman, et al.
The GlucoWatch biographer: a frequent, automatic, and noninvasive glucose monitor.
Ann Med, 32 (2000), pp. 632-641
[9.]
F. Schmidt, W.J. Sluiter, A.J.M. Schoonen.
Glucose concentration in subcutaneous extracellular space.
Diabetes Care, 16 (1993), pp. 695-700
[10.]
F. Sternberg, C. Meyerhoff, F.J. Mennel, F. Bischof, E.F. Pfeiffer.
Subcutaneous glucose concentration in humans.
Diabetes Care, 18 (1995), pp. 1266-1269
[11.]
F.J. Service, P.C. O'Brien, S.D. Wise, S.R. Ness, S.M. LeBlanc.
Dermal interstitial glucose as an indicator of ambient glycemia.
Diabetes Care, 20 (1997), pp. 1426-1429
[12.]
J. Bolinder, U. Ungerstedt, P. Arner.
Microdyalisis measurement of the absolute glucose concentration in subcutaneous adipose tissue allowing glucose monitoring in diabetic patients.
Diabetologia, 35 (1992), pp. 1177-1180
[13.]
K.J. Wientjes, P. Vonk, Y. Vonk Van Klei, A.J.M. Schoonen, N.W. Kossen.
Microdialysis of glucose in subcutaneous adipose tissue up to 3 weeks in healthy volunteers.
Diabetes Care, 21 (1998), pp. 1481-1488
[14.]
K. Rebrin, G.M. Steil, W.P. Van Antwerp, J.J. Mastrototaro.
Subcutaneous glucose predicts plasma glucose independent of insulin: implications for continous monitoring.
Am J Physiol, 277 (1999), pp. E561-E571
[15.]
Summary of safety and effectiveness data for the MiniMed Continous Glucose Monitoring System (CGMS).
PMA P980022, Food and Drug Administration (http://www.fda.gov/cdrh/pdf/p980022html), (1999),
[16.]
B.W. Bode, T.M. Gross, K.R. Thornton, J.J. Mastrototaro.
Continous glucose monitoring used to adjust diabetes therapy improves glycosylated hemoglobin: a pilot study.
Diabetes Res Clin Pract, 46 (1999), pp. 183-190
[17.]
T.M. Gross, B.W. Bode, D. Einhorn, D.M. Kayne, J.H. Reed, N.H. White, et al.
Performance evaluation of the MiniMed Continous Glucose Monitoring System during patient home use.
Diabetes Technology & Therapeutics, 2 (2000), pp. 49-56
[18.]
G.M. Steil, B. Bernaba, M. Saad, J. Mastrototaro, K. Rebrin.
Accurate determination of plasma glucose during hyper-and hypoglycemia with a subcutaneous glucose sensor.
Diabetes, 49 (2000), pp. 510
[19.]
M.S. Boyne, D.M. Silver, J. Kaplan, C.D. Saudek.
Timing of changes in interstitial and blood glucose measured with a continous subcutaneous glucose sensor.
Diabetes, 49 (2000), pp. 398
[20.]
K. Rebrin, W.P. Van Antwerp, J.J. Mastrototaro.
Delay between blood glucose and subcutaneous glucose dynamics in dependence on insulin [resumen 0611].
Diabetes Care, 20A (1997),
[21.]
J.J. Mastrototaro.
The MiniMed Continous Glucose Monitoring System (CGMS).
J Pediatr Endocrinol Metab, 12 (1999), pp. 751-758
[22.]
New insights on glycemic control in the ambulatory setting: MiniMed's Continous Glucose Monitoring System.
Endo Society 82nd Mtg, (2000), pp. P424
[23.]
L.C. Gibson, M.J. Halvorson, S. Carpenter, F.R. Kaufman.
Short-term use of the MiniMed Continous Monitoring System to determine patterns of glycemia in pediatric patients with type 1 DM.
Diabetes, 49 (2000), pp. 438
[24.]
H. Sabbah, K. McCulloch, L. Fredrikson, T.M. Gross, B.W. Bode.
Detailed data from a continous glucose monitoring system (CGMS) facilitates comprehensive diabetes management recommendations.
Diabetes, 49 (2000), pp. 510
[25.]
T.M. Gross, A. Ter Veer, J. Spell, J.J. Mastrototaro.
Continous glucose monitoring in previously unstudied population subgroups.
Diabetes, 49 (2000), pp. 440
[26.]
B.W. Bode, T.M. Gross, K.R. Thornton, J.J. Mastrototaro.
Continous glucose monitoring facilitates sustainable improvements in glycemic control.
Diabetes, 49 (2000), pp. 393
[27.]
B.W. Bode, H. Sabbah, D.G. Robertson, L.C. Tolbert, L.P. Fredrikson.
New opportunities for therapeutic changes with continous glucose sensing.
Diabetes Spectrum, 13 (2000), pp. 171-174
[28.]
T.M. Gross, J.J. Mastrototaro, L.P. Fredrikson.
Detection of unseen hypoglycemia using continous glucose monitoring.
Diabetologia, 43 (2000), pp. 19
[29.]
E. Cheyne, J. Everett, D. Cavan, D. Kerr.
Making sense of type 1 diabetes: unrecognised hypoglycemia during continous glucose sensing.
Diabetologia, 43 (2000), pp. 790
[30.]
E.A. Boland, M. Delucia, C.A. Brandt, M.J. Grey, W.V. Tamborlane.
Limitations of conventional methods of self blood glucose monitoring: lessons learned from three days of continous glucose monitoring (CGMS) in pediatric patients with type 1 diabetes.
Diabetes, 49 (2000), pp. 397
[31.]
G.B. Bolli, G. Perriello, C.G. Fanelli, P. De Feo.
Nocturnal blood glucose control in type 1 diabetes mellitus.
Diabetes Care, 16 (1993), pp. 71-89
[32.]
S. Ilic, L. Jovanovic, L. Jeng.
What is the optimal postprandial glucose monitoring system in gestational diabetes?.
Diabetologia, 43 (2000), pp. 820
Copyright © 2001. Sociedad Española de Endocrinología y Nutrición
Opciones de artículo
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos