Estadísticas

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      "titulo" => "Tipificación molecular y sensibilidad de aislamientos de Candida albicans procedentes de pacientes críticos"
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      "titulo" => "Estudio del gen de la adhesina de Helicobacter pylori: relación con la procedencia de los aislamientos y la enfermedad asociada"
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    "titulo" => "Pirimetamina y sulfadoxina como tratamiento preventivo para la neumonía por Pneumocystis carinii y la encefalitis por Toxoplasma"
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        "titulo" => "Pyrimethamine and sulfadoxine as preventive treatment for pneumonia by Pneumocystis carinii and encephalitis by Toxoplasm"
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        "resumen" => "<span class="elsevierStyleBold">Fundamento&#58;</span> La potencial utilidad de Fansidar&#174;&#44; combinaci&#243;n a dosis fija de pirimetamina y sulfadoxina como profilaxis de la neumon&#237;a por Pneumocystis carinii y encefalitis toxopl&#225;smica ha sido insuficientemente estudiada&#46; <br/> <span class="elsevierStyleBold">M&#233;todos&#58;</span> Revisamos las historias cl&#237;nicas de los pacientes atendidos en nuestra secci&#243;n entre enero de 1992 y diciembre de 1994 a los que se prescribi&#243; pirimetamina y sulfadoxina para este fin&#46; <br/> <span class="elsevierStyleBold">Resultados&#58;</span> Cumpl&#237;an requisitos para su evaluaci&#243;n 157 historias&#46; Treinta y siete pacientes &#40;24&#37;&#41; ten&#237;an un diagn&#243;stico previo de sida&#59; la mediana del recuento de CD4 era 134&#47;mm3&#46; La mediana de seguimiento en tratamiento con Fansidar&#174; fue de 31 meses&#46; Se diagnosticaron 28 casos de neumon&#237;a por Pneumocystis carinii &#40;6&#44;9 casos por 100 pacientes&#47;a&#241;os&#41; y 10 casos de encefalitis toxopl&#225;smica &#40;2&#44;5 casos por 100 pacientes&#47;a&#241;os&#41;&#46; <br/> <span class="elsevierStyleBold">Conclusi&#243;n&#58;</span> Estos valores son similares a los presentados respecto a otras intervenciones farmacol&#243;gicas utilizadas habitualmente para la prevenci&#243;n de neumon&#237;a por Pneumocystis carinii y encefalitis toxopl&#225;smica&#44; y sugieren que pirimetamina y sulfadoxina es una alternativa &#250;til y que requiere consideraci&#243;n en casos individualizados para profilaxis de estas enfermedades&#46;"
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        "resumen" => "<span class="elsevierStyleBold">Background&#58;</span> Few studies have been reported on the potential usefulness of Fansidar&#174; combination at a fixed dosis of pyrimethamine and sulfadoxine as prophylaxis for pneumonia by Pneumocystis carinii and toxoplasmic encephalitis&#46; <br/> <span class="elsevierStyleBold">Methods&#58;</span> The clinical histories of the patients seen in our department from January&#44; 1992 to December&#44; 1994 who were prescribed pyrimethamine and sulfadoxine for the above prophylactic treatment were reviewed&#46; <br/> <span class="elsevierStyleBold">Results&#58;</span> One hundred fifty clinical histories fulfilled the requisites for evaluation&#46; Thirty-seven patients &#40;24&#37;&#41; had a previous of AIDS&#44; with the median CD4 count being of 134&#47;mm3&#46; The median follow up of treatment with Fansidar&#174; was of 31 months&#46; Twenty-eight cases of pneumonia by Pneumocystis carinii &#40;6&#46;9 cases for 100 patients-years&#41; and 10 cases of toxoplasmic encephalitis &#40;2&#46;5 cases for 100 patients-years&#41; were diagnosed&#46; <br/> <span class="elsevierStyleBold">Conclusions&#58;</span> These values are similar to those presented with respect to other pharmacologic interventions commonly used for the prevention of pneumonia by Pneumocystis carinii and toxoplasmic encephalitis and suggest that pyrimethamine and sulfadoxine is a useful alternative and requires consideration in individualized cases for the prophylaxis of these diseases&#46;"
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