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"apellidos" => "Pérez-Mateo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Unidad Hepática. Sección de Aparato Digestivo. Servicio de Medicina Interna. Hospital General Universitario de Alicante" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dra. S. Pascual Bartolomé. Unidad Hepática. Servicio de Medicina Interna. Hospital General Universitario de Alicante. Pintor Baeza, s/n. 03010 Alicante." ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2001-01-02" "fechaAceptado" => "2001-01-08" "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:119 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal Epithelial Hyperpermeability. Mechanisms and relevance to disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterol Clin North Am" "fecha" => "1998" "volumen" => "27" "paginaInicial" => "289" "paginaFinal" => "307" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nonhereditary colonic angiodysplasias: Histomorphometric approach to their pathogenesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1995" "volumen" => "40" "paginaInicial" => "839" "paginaFinal" => "842" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability: an overview" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1995" "volumen" => "108" "paginaInicial" => "1566" "paginaFinal" => "1581" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1994" "volumen" => "36" "numero" => "Supl 1" "paginaInicial" => "18" "paginaFinal" => "22" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heymans HSA. Clinical implications of the sugar absortion test: intestinal permeability test to asses mucosal barrier function" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ …5] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1997" "volumen" => "32" "numero" => "Supl 223" "paginaInicial" => "70" "paginaFinal" => "78" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The epithelial «membrane» of the small intestine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Clin Nutr" "fecha" => "1971" "volumen" => "24" "paginaInicial" => "45" "paginaFinal" => "64" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Anatomy and anomalies of the small and large intestines" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Gastrointestinal and liver disease" "paginaInicial" => "1419" "paginaFinal" => "1436" "serieFecha" => "1998" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal electrolyte absortion and secretion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Gastrointestinal and liver disease" "paginaInicial" => "1451" "paginaFinal" => "1471" "serieFecha" => "1998" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Étude de la perméabilité intestinale chez l'homme" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterol Clin Biol" "fecha" => "1994" "volumen" => "18" "paginaInicial" => "638" "paginaFinal" => "648" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability: functional assesment and significance" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Sci" "fecha" => "1992" "volumen" => "82" "paginaInicial" => "471" "paginaFinal" => "488" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Permeability characteristics of the human small intestine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ …5] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI105299" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "1965" "volumen" => "44" "paginaInicial" => "1935" "paginaFinal" => "1944" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of the tigh junction structure-function relationship" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Membr Biol" "fecha" => "1984" "volumen" => "80" "paginaInicial" => "59" "paginaFinal" => "70" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Structure, biochemistry, and assembly of epithelial tigh junctions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Physiol" "fecha" => "1987" "volumen" => "253" "paginaInicial" => "C749" "paginaFinal" => "C758" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The epithelial tigh junction: structure, function and preliminary biochemical characterization" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Mol Cell Biochem" "fecha" => "1988" "volumen" => "83" "paginaInicial" => "129" "paginaFinal" => "145" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1992" "volumen" => "27" "paginaInicial" => "721" "paginaFinal" => "726" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Boyd CAR. Importance of «probe» molecular geometry in determining intestinal permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Can J Gastroenterol" "fecha" => "1988" "volumen" => "2" "numero" => "Supl A" "paginaInicial" => "35" "paginaFinal" => "38" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "IEC-18, a nontransformed small intestinal cell line for studying epithelial permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ …5] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Lab Clin Med" "fecha" => "1992" "volumen" => "120" "paginaInicial" => "329" "paginaFinal" => "341" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of changing intestinal flow rate on a measurement of intestinal permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1995" "volumen" => "108" "paginaInicial" => "983" "paginaFinal" => "989" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Measuraments of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). I. Chemical analysis and biological propiertie of PEG 400" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1977" "volumen" => "73" "paginaInicial" => "241" "paginaFinal" => "246" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Measuraments of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Applications to study of normal and abnormal permeability states in man and animals" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1977" "volumen" => "73" "paginaInicial" => "247" "paginaFinal" => "251" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lactulose, 51CrEDTA, L-Rhamnose and polyethylene glycol 400 as probe markers for in vivo assessment of human intestinal permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Sci" "fecha" => "1986" "volumen" => "71" "paginaInicial" => "71" "paginaFinal" => "80" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Viewpoints in Intestinal Permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1997" "volumen" => "112" "paginaInicial" => "669" "paginaFinal" => "673" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Small intestinal permeability to mannitol, lactulose, and polyethylene glycol 400 in celiac disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1984" "volumen" => "29" "paginaInicial" => "809" "paginaFinal" => "816" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Assessment of intestinal permeability with twohour urine collection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1998" "volumen" => "43" "paginaInicial" => "1946" "paginaFinal" => "1950" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Measurement of small intestinal permeability markers, lactulose, and mannitol in serum" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1999" "volumen" => "44" "paginaInicial" => "402" "paginaFinal" => "406" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Brummer R-JM. The sensitivity of the lactulose/rahmnose gut permeability test" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Clin Invest" "fecha" => "1999" "volumen" => "44" "paginaInicial" => "402" "paginaFinal" => "406" ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Test conditions greatly influence permeation of water soluble molecules throgh the intestinal mucosa: need for standarsitation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1994" "volumen" => "35" "paginaInicial" => "1404" "paginaFinal" => "1408" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1993" "volumen" => "104" "paginaInicial" => "1832" "paginaFinal" => "1847" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The double sugar test of intestinal permeability in the eldery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Age Aging" "fecha" => "1985" "volumen" => "14" "paginaInicial" => "312" "paginaFinal" => "315" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in small-intestine permeability with aging" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Geriatr Soc" "fecha" => "1995" "volumen" => "43" "paginaInicial" => "160" "paginaFinal" => "164" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of the lactulose/mannitol and 51Cr-Ethylenediaminetettraacetic Acid/14C-mannitol methods for the intestinal permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1997" "volumen" => "32" "paginaInicial" => "805" "paginaFinal" => "812" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Does smoking tighten the gut?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Scan J Gastroenterol" "fecha" => "1989" "volumen" => "24" "paginaInicial" => "1084" "paginaFinal" => "1088" ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low-molecular weigth polyethylene glycol as a probe of gastrointestinal permeability after alcohol ingestion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ …5] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1981" "volumen" => "26" "paginaInicial" => "971" "paginaFinal" => "977" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The leaky gut of alcoholism: possible route of entry for toxic compounds" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1984" "volumen" => "1" "paginaInicial" => "179" "paginaFinal" => "182" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0175" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Absorption of nutrient solution in chronic alcoholics without nutrient deficiencies and liver cirrhosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ …5] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1992" "volumen" => "27" ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0180" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The differing effects of acute and chronic alcohol on gastric and intestinal permeability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "1994" "volumen" => "89" "paginaInicial" => "2205" "paginaFinal" => "2221" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib0185" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gastrointestinal complications of nonsteroidal anti-inflammatory drugs: prophilactic and therapeutic strategies" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Am J Med" "fecha" => "1994" "volumen" => "96" "paginaInicial" => "281" ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0190" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Small-bowell side-effects of non-steroidal anti-inflammatory drugs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Gastroenterol Hepatol" "fecha" => "1999" "volumen" => "11" "paginaInicial" => "383" "paginaFinal" => "388" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib0195" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of nonsteroidal anti-inflammatory drugs on permeability of the small intestine in humans" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Rheumatol" "fecha" => "1992" "volumen" => "19" "numero" => "Supl 36" "paginaInicial" => "83" "paginaFinal" => "84" "link" => array:1 [ …1] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib0200" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased intestinal permeability in patients with rheumatoid arthritis: a side effect of nonsteroidal anti-inflammatory drugs therapy" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Rheumatol" "fecha" => "1987" "volumen" => "26" "paginaInicial" => "104" "paginaFinal" => "107" ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib0205" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of nonsteroidal anti-inflammatory drugs and prostaglandin on the permeability of the human small intestine" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1986" "volumen" => "27" "paginaInicial" => "1292" "paginaFinal" => "1297" "link" => array:1 [ …1] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib0210" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Importance of local versus systemic effects of non-steroidal antiinflammatory drugs in increasing small intestinal permeability in man" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1991" "volumen" => "32" "paginaInicial" => "275" "paginaFinal" => "277" "link" => array:1 [ …1] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib0215" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability and inflammation in patiens on NSAIDs" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1998" "volumen" => "43" "paginaInicial" => "506" "paginaFinal" => "511" "link" => array:1 [ …1] ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib0220" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The pro-drug sulindac may reduce the risk of intestinal damage associated with the use of conventional non-steroidal anti-inflammatory drugs" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Aliment Pharmacol Ther" "fecha" => "1991" "volumen" => "5" "paginaInicial" => "593" "paginaFinal" => "598" "link" => array:1 [ …1] ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib0225" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Do non-steroidal anti-inflammatory drugs increase colonic permeability?" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1991" "volumen" => "32" "paginaInicial" => "66" "paginaFinal" => "69" "link" => array:1 [ …1] ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib0230" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability to different size polythelene glycols in patients with rheumatoid arthritis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Rheumatol" "fecha" => "1983" "volumen" => "12" "paginaInicial" => "124" "paginaFinal" => "128" "link" => array:1 [ …1] ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib0235" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1995" "volumen" => "37" "paginaInicial" => "623" "paginaFinal" => "629" "link" => array:1 [ …1] ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib0240" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability and function in patients infected with human immunodeficiency virus" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1993" "volumen" => "28" "paginaInicial" => "573" "paginaFinal" => "580" "link" => array:1 [ …1] ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib0245" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in patients infected with the human immunodeficiency virus" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "1994" "volumen" => "89" "paginaInicial" => "878" "paginaFinal" => "882" "link" => array:1 [ …1] ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib0250" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal absortion and permeability in human immunodeficiency virus-infected patients" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1999" "volumen" => "34" "paginaInicial" => "29" "paginaFinal" => "34" "link" => array:1 [ …1] ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib0255" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased intestinal permeability associated with infection in burn patients" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Surg" "fecha" => "1988" "volumen" => "123" "paginaInicial" => "1313" "paginaFinal" => "1319" "link" => array:1 [ …1] ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib0260" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability is increased in burn patients shortly after injury" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Surgery" "fecha" => "1990" "volumen" => "102" "paginaInicial" => "411" "paginaFinal" => "412" ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib0265" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased intestinal permeability following blunt and penetrating trauma" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Crit Care Med" "fecha" => "1995" "volumen" => "23" "paginaInicial" => "660" "paginaFinal" => "664" "link" => array:1 [ …1] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib0270" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability after severe trauma and hemorrhagic shock is increased without relation to septic complications" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Surg" "fecha" => "1993" "volumen" => "128" "paginaInicial" => "453" "paginaFinal" => "457" "link" => array:1 [ …1] ] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib0275" "etiqueta" => "55." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of intestinal hypoperfusion on intestinal absorption and permeability during cardiopulmonary bypass" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1994" "volumen" => "106" "paginaInicial" => "318" "paginaFinal" => "323" "link" => array:1 [ …1] ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib0280" "etiqueta" => "56." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gut barrier function in malnourished patients" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1998" "volumen" => "42" "paginaInicial" => "396" "paginaFinal" => "401" "link" => array:1 [ …1] ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib0285" "etiqueta" => "57." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased permeability in kwashiorkor" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dis Child" "fecha" => "1997" "volumen" => "76" "paginaInicial" => "236" "paginaFinal" => "241" "link" => array:1 [ …1] ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib0290" "etiqueta" => "58." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of total starvation and very low calorie diets on intestinal permeability in man" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Sci" "fecha" => "1987" "volumen" => "73" "paginaInicial" => "205" "paginaFinal" => "210" "link" => array:1 [ …1] ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib0295" "etiqueta" => "59." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gut permeability, intestinal morphology and nutritional depletion" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Nutrition" "fecha" => "1998" "volumen" => "14" "paginaInicial" => "1" "paginaFinal" => "6" "link" => array:1 [ …1] ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib0300" "etiqueta" => "60." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal malabsorption and hyperpermeability during enteral nutrition" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Clin Sci" "fecha" => "1984" "volumen" => "67" "paginaInicial" => "36A" ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib0305" "etiqueta" => "61." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Total parenteral nutrition-induced changes in gut function: atrophy alone is not the issue" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surgery" "fecha" => "1992" "volumen" => "112" "paginaInicial" => "631" "paginaFinal" => "637" "link" => array:1 [ …1] ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib0310" "etiqueta" => "62." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preoperative total parenteral nutrition is not associated with mucosal atrophy or bacterial translocation in humans" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1995" "volumen" => "82" "paginaInicial" => "1663" "paginaFinal" => "1667" "link" => array:1 [ …1] ] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib0315" "etiqueta" => "63." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in active pulmonary sarcoidosis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/145.6.1440" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1992" "volumen" => "145" "paginaInicial" => "1440" "paginaFinal" => "1445" "link" => array:1 [ …1] ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib0320" "etiqueta" => "64." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal Permability to 51CrEDTA in children with cystic fibrosis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Pediatr Gastroenterol Nutr" "fecha" => "1986" "volumen" => "5" "paginaInicial" => "384" "paginaFinal" => "387" "link" => array:1 [ …1] ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib0325" "etiqueta" => "65." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased intestinal permeability in bronchial asthma" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1996" "volumen" => "97" "paginaInicial" => "1173" "paginaFinal" => "1178" "link" => array:1 [ …1] ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib0330" "etiqueta" => "66." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in patiens with atopic eczema" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1985" "volumen" => "112" "paginaInicial" => "291" "paginaFinal" => "297" "link" => array:1 [ …1] ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib0335" "etiqueta" => "67." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Digestive permeability to different-size molecules and to sodium cromoglycate in food allergy" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Allergy Proc" "fecha" => "1991" "volumen" => "12" "paginaInicial" => "293" "paginaFinal" => "298" "link" => array:1 [ …1] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib0340" "etiqueta" => "68." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "(51Cr) EDTA intestinal permeability in children with cow's milk intolerance" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Pediatr Gastroenterol Nutr" "fecha" => "1990" "volumen" => "10" "paginaInicial" => "189" "paginaFinal" => "192" "link" => array:1 [ …1] ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib0345" "etiqueta" => "69." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Abnormal intestinal permeability: an aetiological factor in chronic psychiatric disorders" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Psychiatr" "fecha" => "1987" "volumen" => "151" "paginaInicial" => "704" "paginaFinal" => "705" ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib0350" "etiqueta" => "70." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "O'Brien IAD. Intestinal permeability in diabetic diarrhoea" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Diabetes Med" "fecha" => "1987" "volumen" => "4" "paginaInicial" => "49" "paginaFinal" => "52" ] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib0355" "etiqueta" => "71." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oral chenodeoxycholic acid increases small intestinal permeability to lactulose in humans" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "1988" "volumen" => "83" "paginaInicial" => "541" "paginaFinal" => "544" "link" => array:1 [ …1] ] ] ] ] ] ] 71 => array:3 [ "identificador" => "bib0360" "etiqueta" => "72." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cyclohosphamide priming reduces intestinal damage in man following high dose melphalan chemotherapy" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Cancer" "fecha" => "1987" "volumen" => "55" "paginaInicial" => "531" "paginaFinal" => "533" "link" => array:1 [ …1] ] ] ] ] ] ] 72 => array:3 [ "identificador" => "bib0365" "etiqueta" => "73." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased intestinal absorption of large molecules in patients after 5-flourouracil therapy for metastasic colon carcinoma" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer Res" "fecha" => "1980" "volumen" => "40" "paginaInicial" => "3430" "paginaFinal" => "3436" "link" => array:1 [ …1] ] ] ] ] ] ] 73 => array:3 [ "identificador" => "bib0370" "etiqueta" => "74." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in the gastrointestinal mucosa after long-distance running" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1992" "volumen" => "27" "paginaInicial" => "270" "paginaFinal" => "274" "link" => array:1 [ …1] ] ] ] ] ] ] 74 => array:3 [ "identificador" => "bib0375" "etiqueta" => "75." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Review article: intestinal permeability in Crohn's disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Aliment Pharmacol Ther" "fecha" => "1997" "volumen" => "11" "paginaInicial" => "47" "paginaFinal" => "56" "link" => array:1 [ …1] ] ] ] ] ] ] 75 => array:3 [ "identificador" => "bib0380" "etiqueta" => "76." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Abnormal Intestinal Permeability in Crohn's Disease. A Possible Pathogenic Factor" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1990" "volumen" => "25" "paginaInicial" => "321" "paginaFinal" => "328" "link" => array:1 [ …1] ] ] ] ] ] ] 76 => array:3 [ "identificador" => "bib0385" "etiqueta" => "77." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased absorption of polyethylene glycol 600 deposited in colon in active ulcerative colitis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1993" "volumen" => "34" "paginaInicial" => "509" "paginaFinal" => "513" "link" => array:1 [ …1] ] ] ] ] ] ] 77 => array:3 [ "identificador" => "bib0390" "etiqueta" => "78." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability to 51Crethylenediaminetetraacetate in patients with ulcerative colitis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "1993" "volumen" => "88" "paginaInicial" => "1978" "paginaFinal" => "1981" "link" => array:1 [ …1] ] ] ] ] ] ] 78 => array:3 [ "identificador" => "bib0395" "etiqueta" => "79." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in Crohn's disease and its relation to disease activity and relapse following treatment with elemental diet" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Gastroenterol Hepatol" "fecha" => "1993" "volumen" => "5" "paginaInicial" => "79" "paginaFinal" => "84" ] ] ] ] ] ] 79 => array:3 [ "identificador" => "bib0400" "etiqueta" => "80." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of elemental diet on intestinal permeability and inflammation in Crohn's disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1991" "volumen" => "101" "paginaInicial" => "84" "paginaFinal" => "89" "link" => array:1 [ …1] ] ] ] ] ] ] 80 => array:3 [ "identificador" => "bib0405" "etiqueta" => "81." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability and the prediction of relapse in Crohn's disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1993" "volumen" => "341" "paginaInicial" => "1437" "paginaFinal" => "1439" "link" => array:1 [ …1] ] ] ] ] ] ] 81 => array:3 [ "identificador" => "bib0410" "etiqueta" => "82." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Crohn's disease a permeability disorder of the tight junction?" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1988" "volumen" => "29" "paginaInicial" => "1621" "paginaFinal" => "1624" "link" => array:1 [ …1] ] ] ] ] ] ] 82 => array:3 [ "identificador" => "bib0415" "etiqueta" => "83." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Enhanced absorption of macromolecules. A secondary factor in Crohn's disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1996" "volumen" => "41" "paginaInicial" => "1423" "paginaFinal" => "1428" "link" => array:1 [ …1] ] ] ] ] ] ] 83 => array:3 [ "identificador" => "bib0420" "etiqueta" => "84." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clustering of increased small intestinal permeability in families with Crohn's disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1997" "volumen" => "113" "paginaInicial" => "802" "paginaFinal" => "807" "link" => array:1 [ …1] ] ] ] ] ] ] 84 => array:3 [ "identificador" => "bib0425" "etiqueta" => "85." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Permeability in Crohn's disease: altered barrier functions in healthy relatives?" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1993" "volumen" => "104" "paginaInicial" => "1848" "paginaFinal" => "1873" "link" => array:1 [ …1] ] ] ] ] ] ] 85 => array:3 [ "identificador" => "bib0430" "etiqueta" => "86." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in patients with Crohn's disease and ulcerative colitis and their firts degree relatives" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1994" "volumen" => "35" "paginaInicial" => "68" "paginaFinal" => "72" "link" => array:1 [ …1] ] ] ] ] ] ] 86 => array:3 [ "identificador" => "bib0435" "etiqueta" => "87." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in patients with Crohn's disease and their first degree relatives" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1992" "volumen" => "33" "paginaInicial" => "320" "paginaFinal" => "323" "link" => array:1 [ …1] ] ] ] ] ] ] 87 => array:3 [ "identificador" => "bib0440" "etiqueta" => "88." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is intestinal permeability really increased in relatives of patients with Crohn's disease?" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1993" "volumen" => "104" "paginaInicial" => "1627" "paginaFinal" => "1632" "link" => array:1 [ …1] ] ] ] ] ] ] 88 => array:3 [ "identificador" => "bib0445" "etiqueta" => "89." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of non-steroidal anti-inflammatory drugs (NSAID) on intestinal permeability in first degree relatives of patients with Crohn's disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Gastroenterology" "fecha" => "1992" "volumen" => "102" "paginaInicial" => "A679" ] ] ] ] ] ] 89 => array:3 [ "identificador" => "bib0450" "etiqueta" => "90." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Decreased gastrointestinal absorption of different-size polyethylene glycols (PEG 1000) in Crohn's disease: a sign of jejunal abnormality" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Chir Scand" "fecha" => "1987" "volumen" => "153" "paginaInicial" => "373" "paginaFinal" => "377" "link" => array:1 [ …1] ] ] ] ] ] ] 90 => array:3 [ "identificador" => "bib0455" "etiqueta" => "91." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability to polyethylene glycol 600 in Crohn's disease. Perioperative determination in a defined segment of the small bowell" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1988" "volumen" => "29" "paginaInicial" => "196" "paginaFinal" => "199" "link" => array:1 [ …1] ] ] ] ] ] ] 91 => array:3 [ "identificador" => "bib0460" "etiqueta" => "92." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Assesing the site of increased intestinal permeability in coeliac and inflammatory bowel disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1996" "volumen" => "38" "paginaInicial" => "864" "paginaFinal" => "869" "link" => array:1 [ …1] ] ] ] ] ] ] 92 => array:3 [ "identificador" => "bib0465" "etiqueta" => "93." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of Four markers of intestinal permeability in control subjects and patients with coeliac disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Gastroenterol" "fecha" => "1994" "volumen" => "29" "paginaInicial" => "630" "paginaFinal" => "639" "link" => array:1 [ …1] ] ] ] ] ] ] 93 => array:3 [ "identificador" => "bib0470" "etiqueta" => "94." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Axon ATR. Intestinal permeability assessed by excretion ratios of two molecules: results in coeliac disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br Med J" "fecha" => "1978" "volumen" => "2" "paginaInicial" => "1060" "link" => array:1 [ …1] ] ] ] ] ] ] 94 => array:3 [ "identificador" => "bib0475" "etiqueta" => "95." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Axon ATR. Cellobiose/mannitol sugar test-a sensitive tubeless test for coeliac disease: results on 1010 unselected patients" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1989" "volumen" => "30" "paginaInicial" => "476" "paginaFinal" => "480" "link" => array:1 [ …1] ] ] ] ] ] ] 95 => array:3 [ "identificador" => "bib0480" "etiqueta" => "96." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Axon ATR. Intestinal permeability in coeliac disease: the response to gluten withdrawal and single-dose gluten challenge" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1982" "volumen" => "23" "paginaInicial" => "202" "paginaFinal" => "210" "link" => array:1 [ …1] ] ] ] ] ] ] 96 => array:3 [ "identificador" => "bib0485" "etiqueta" => "97." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential in vivo and in vitro intestinal permeability to lactulose and mannitol in animals and humans: a hypothesis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1995" "volumen" => "108" "paginaInicial" => "687" "paginaFinal" => "696" "link" => array:1 [ …1] ] ] ] ] ] ] 97 => array:3 [ "identificador" => "bib0490" "etiqueta" => "98." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gastrointestinal permeability in coeliac disease" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1997" "volumen" => "112" "paginaInicial" => "1129" "paginaFinal" => "1136" "link" => array:1 [ …1] ] ] ] ] ] ] 98 => array:3 [ "identificador" => "bib0495" "etiqueta" => "99." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal barrier dysfunction in clinical and experimental obstructive jaundice and its reversal by internal biliary drainage" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1996" "volumen" => "83" "paginaInicial" => "1345" "paginaFinal" => "1349" "link" => array:1 [ …1] ] ] ] ] ] ] 99 => array:3 [ "identificador" => "bib0500" "etiqueta" => "100." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased intestinal permeability and altered mucosal immunity in cholestatic jaundice" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1998" "volumen" => "227" "paginaInicial" => "205" "paginaFinal" => "212" "link" => array:1 [ …1] ] ] ] ] ] ] 100 => array:3 [ "identificador" => "bib0505" "etiqueta" => "101." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability to [51Cr]EDTA in infectious diarrhea" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1993" "volumen" => "38" "paginaInicial" => "1651" "paginaFinal" => "1657" "link" => array:1 [ …1] ] ] ] ] ] ] 101 => array:3 [ "identificador" => "bib0510" "etiqueta" => "102." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Investigation of intestine function during acute viral hepatitis using combined sugar oral load" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1987" "volumen" => "28" "paginaInicial" => "1439" "paginaFinal" => "1444" "link" => array:1 [ …1] ] ] ] ] ] ] 102 => array:3 [ "identificador" => "bib0515" "etiqueta" => "103." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Small intestinal absorption of polythylene glycol 400 to 1000 in the portacaval shunted Rat" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Hepatology" "fecha" => "1995" "volumen" => "21" "paginaInicial" => "1167" "paginaFinal" => "1173" "link" => array:1 [ …1] ] ] ] ] ] ] 103 => array:3 [ "identificador" => "bib0520" "etiqueta" => "104." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The process of microbial translocation" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1990" "volumen" => "212" "paginaInicial" => "496" "paginaFinal" => "510" "link" => array:1 [ …1] ] ] ] ] ] ] 104 => array:3 [ "identificador" => "bib0525" "etiqueta" => "105." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bacterial translocation from the gastrointestinal tract" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Med" "fecha" => "1992" "volumen" => "23" "paginaInicial" => "217" "paginaFinal" => "244" "link" => array:1 [ …1] ] ] ] ] ] ] 105 => array:3 [ "identificador" => "bib0530" "etiqueta" => "106." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Investigation of intestine and liver function in cirrhosis using combined sugar oral loads" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Hepatol" "fecha" => "1985" "volumen" => "1" "paginaInicial" => "513" "paginaFinal" => "524" "link" => array:1 [ …1] ] ] ] ] ] ] 106 => array:3 [ "identificador" => "bib0535" "etiqueta" => "107." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wilson JHP. Small bowel wall function in patients with advanced liver cirrhosis and portal hypertension: studies on permeability and luminal bacterial overgrowth" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Gastroenterol Hepatol" "fecha" => "1993" "volumen" => "5" "paginaInicial" => "383" "paginaFinal" => "387" ] ] ] ] ] ] 107 => array:3 [ "identificador" => "bib0540" "etiqueta" => "108." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability as measured with polyethylene glycol 600 in patients with cirrhosis: clinical investigation" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Gastroenterology" "fecha" => "1995" "volumen" => "108" "paginaInicial" => "A1079" ] ] ] ] ] ] 108 => array:3 [ "identificador" => "bib0545" "etiqueta" => "109." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in liver cirrhosis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Gastroenterol Hepatol" "fecha" => "1999" "volumen" => "11" "paginaInicial" => "409" "paginaFinal" => "412" "link" => array:1 [ …1] ] ] ] ] ] ] 109 => array:3 [ "identificador" => "bib0550" "etiqueta" => "110." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intestinal permeability in liver cirrhosis: relationship with severe septic complications" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Gastroenterol Hepatol" "fecha" => "1999" "volumen" => "11" "paginaInicial" => "755" "paginaFinal" => "759" "link" => array:1 [ …1] ] ] ] ] ] ] 110 => array:3 [ "identificador" => "bib0555" "etiqueta" => "111." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Permeabilidad intestinal en la cirrosis: estudio de absorción de macromoléculas" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Gastroenterol Hepatol" "fecha" => "2000" "volumen" => "23" "paginaInicial" => "A132" ] ] ] ] ] ] 111 => array:3 [ "identificador" => "bib0560" "etiqueta" => "112." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Small intestinal permeability" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Curr Op Gastroenterol" "fecha" => "2000" "volumen" => "16" "paginaInicial" => "134" "paginaFinal" => "139" ] ] ] ] ] ] 112 => array:3 [ "identificador" => "bib0565" "etiqueta" => "113." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "La respuesta inflamatoria en al fase inicial de la pancreatitis aguda: relación con el comienzo y la gravedad de la enfermedad" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Esp Enferm Digest" "fecha" => "1995" "volumen" => "3" "paginaInicial" => "236" "paginaFinal" => "246" ] ] ] ] ] ] 113 => array:3 [ "identificador" => "bib0570" "etiqueta" => "114." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endotoxemia predicts outcome in acute pancreatitis" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Gastroenterol" "fecha" => "1998" "volumen" => "26" "paginaInicial" => "121" "paginaFinal" => "124" "link" => array:1 [ …1] ] ] ] ] ] ] 114 => array:3 [ "identificador" => "bib0575" "etiqueta" => "115." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estudio sobre el valor de la endotoxina en el pronóstico de la pancreatitis aguda" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Rev Esp Enferm Digest" "fecha" => "1998" "volumen" => "10" "paginaInicial" => "761" ] ] ] ] ] ] 115 => array:3 [ "identificador" => "bib0580" "etiqueta" => "116." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gut macromolecular permeability in pancreatitis correlates with severity of disease in rats" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1993" "volumen" => "104" "paginaInicial" => "890" "paginaFinal" => "895" "link" => array:1 [ …1] ] ] ] ] ] ] 116 => array:3 [ "identificador" => "bib0585" "etiqueta" => "117." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alterations in intestinal function in acute pancreatitis in an experimental model" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1996" "volumen" => "83" "paginaInicial" => "1537" "paginaFinal" => "1542" "link" => array:1 [ …1] ] ] ] ] ] ] 117 => array:3 [ "identificador" => "bib0590" "etiqueta" => "118." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Early increase in intestinal permeability in patients with severe acute pancreatitis: correlation with endotoxemia, organ failure and mortality" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Gastrointest Surg" "fecha" => "1999" "volumen" => "3" "paginaInicial" => "252" "paginaFinal" => "262" "link" => array:1 [ …1] ] ] ] ] ] ] 118 => array:3 [ "identificador" => "bib0595" "etiqueta" => "119." 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Información de la revista
Vol. 24. Núm. 5.
Páginas 256-267 (enero 2001)
Vol. 24. Núm. 5.
Páginas 256-267 (enero 2001)
Acceso a texto completo
La barrera intestinal: trastornos funcionales en enfermedades digestivas y extradigestivas
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15098
S. Pascual
, J. Martínez, M. Pérez-Mateo
Autor para correspondencia
pascual_son@gva.es
Correspondencia: Dra. S. Pascual Bartolomé. Unidad Hepática. Servicio de Medicina Interna. Hospital General Universitario de Alicante. Pintor Baeza, s/n. 03010 Alicante.
Correspondencia: Dra. S. Pascual Bartolomé. Unidad Hepática. Servicio de Medicina Interna. Hospital General Universitario de Alicante. Pintor Baeza, s/n. 03010 Alicante.
Unidad Hepática. Sección de Aparato Digestivo. Servicio de Medicina Interna. Hospital General Universitario de Alicante
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Bibliografía
[1.]
N. Unno, M.P. Fink.
Intestinal Epithelial Hyperpermeability. Mechanisms and relevance to disease.
Gastroenterol Clin North Am, 27 (1998), pp. 289-307
[2.]
S. Nauveau, M.B. Leger-Ravet, C. Houdayer, P. Bedossa, G. Lemaigre, J.C. Chaput.
Nonhereditary colonic angiodysplasias: Histomorphometric approach to their pathogenesis.
Dig Dis Sci, 40 (1995), pp. 839-842
[3.]
I. Bjarnason, A. MacPherson, D. Hollander.
Intestinal permeability: an overview.
Gastroenterology, 108 (1995), pp. 1566-1581
[4.]
I. Bjarnason.
Intestinal permeability.
Gut, 36 (1994), pp. 18-22
[5.]
J.J. Uil, R.M. Van Elburg, F.M. Van Overbeek, C.J.J. Mulder, G.P. Vanberge-Henegouwen.
Heymans HSA. Clinical implications of the sugar absortion test: intestinal permeability test to asses mucosal barrier function.
Scand J Gastroenterol, 32 (1997), pp. 70-78
[6.]
W. Rubin.
The epithelial «membrane» of the small intestine.
Am J Clin Nutr, 24 (1971), pp. 45-64
[7.]
D.J. Keljo, R.H. Squires.
Anatomy and anomalies of the small and large intestines.
Gastrointestinal and liver disease, pp. 1419-1436
[8.]
J.H. Sellin.
Intestinal electrolyte absortion and secretion.
Gastrointestinal and liver disease, pp. 1451-1471
[9.]
D. Heresbach, R. Le Gall, J.F. Bretagne, M. Gosselin.
Étude de la perméabilité intestinale chez l'homme.
Gastroenterol Clin Biol, 18 (1994), pp. 638-648
[10.]
S. Travis, I.S. Menzies.
Intestinal permeability: functional assesment and significance.
Clin Sci, 82 (1992), pp. 471-488
[11.]
J.S. Fordtran, F.C. Rector, M.F. Ewton, N. Soter, J. Kinney.
Permeability characteristics of the human small intestine.
J Clin Invest, 44 (1965), pp. 1935-1944
[12.]
M.A. Marcial, S.L. Carlson, J.L. Madara.
Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of the tigh junction structure-function relationship.
J Membr Biol, 80 (1984), pp. 59-70
[13.]
B. Gumbier.
Structure, biochemistry, and assembly of epithelial tigh junctions.
Am J Physiol, 253 (1987), pp. C749-C758
[14.]
B.R. Stevenson, J.M. Anderson, S. Bullivant.
The epithelial tigh junction: structure, function and preliminary biochemical characterization.
Mol Cell Biochem, 83 (1988), pp. 129-145
[15.]
D. Hollander.
The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease.
Scand J Gastroenterol, 27 (1992), pp. 721-726
[16.]
D. Hollander, D. Rickets.
Boyd CAR. Importance of «probe» molecular geometry in determining intestinal permeability.
Can J Gastroenterol, 2 (1988), pp. 35-38
[17.]
T.Y. Ma, D. Hollander, D. Bhalla, H. Nguyen, P. Krugliak.
IEC-18, a nontransformed small intestinal cell line for studying epithelial permeability.
J Lab Clin Med, 120 (1992), pp. 329-341
[18.]
K.D. Fine, C.A. Santa Ana, J.L. Porter, J.S. Fordtran.
Effect of changing intestinal flow rate on a measurement of intestinal permeability.
Gastroenterology, 108 (1995), pp. 983-989
[19.]
V.S. Chadwick, S.F. Philips, A.F. Hofman.
Measuraments of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). I. Chemical analysis and biological propiertie of PEG 400.
Gastroenterology, 73 (1977), pp. 241-246
[20.]
V.S. Chadwick, S.F. Philips, A.F. Hofman.
Measuraments of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Applications to study of normal and abnormal permeability states in man and animals.
Gastroenterology, 73 (1977), pp. 247-251
[21.]
D.G. Maxton, I. Bjarnasson, A.P. Reynolds, S. Catt, T.J. Peters, I.S. Menzies.
Lactulose, 51CrEDTA, L-Rhamnose and polyethylene glycol 400 as probe markers for in vivo assessment of human intestinal permeability.
Clin Sci, 71 (1986), pp. 71-80
[22.]
M.A. Cox, T.H. Igbal, K.O. Lewis, B.T. Cooper.
Viewpoints in Intestinal Permeability.
Gastroenterology, 112 (1997), pp. 669-673
[23.]
S.O. Ukabam, B.T. Coper.
Small intestinal permeability to mannitol, lactulose, and polyethylene glycol 400 in celiac disease.
Dig Dis Sci, 29 (1984), pp. 809-816
[24.]
S. Akram, S. Mourani, C-N Ou, C. Rognerud, R. Saqid, R.W. Goodgame.
Assessment of intestinal permeability with twohour urine collection.
Dig Dis Sci, 43 (1998), pp. 1946-1950
[25.]
M.A. Cox, K.O. Lewis, B.T. Cooper.
Measurement of small intestinal permeability markers, lactulose, and mannitol in serum.
Dig Dis Sci, 44 (1999), pp. 402-406
[26.]
M.A. Van Nievewenhoven, B.J. Geerling, N.E.P. Deutz, F. Brouns.
Brummer R-JM. The sensitivity of the lactulose/rahmnose gut permeability test.
Eur J Clin Invest, 44 (1999), pp. 402-406
[27.]
M. Peeters, M. Hiele, Y. Ghoos, V. Huysmans, K. Geboes, G. Vantrappen, et al.
Test conditions greatly influence permeation of water soluble molecules throgh the intestinal mucosa: need for standarsitation.
Gut, 35 (1994), pp. 1404-1408
[28.]
I. Bjarnason, J. Hayllar, A.J. MacPherson, A.S. Russell.
Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans.
Gastroenterology, 104 (1993), pp. 1832-1847
[29.]
W.M. Sawiers, D.J. Andrews, T.S. Low-Beers.
The double sugar test of intestinal permeability in the eldery.
Age Aging, 14 (1985), pp. 312-315
[30.]
J.R. Saltzman, K.V. Kowdley, G. Perrone, R.M. Russel.
Changes in small-intestine permeability with aging.
J Am Geriatr Soc, 43 (1995), pp. 160-164
[31.]
L. Blomquist, T. Bark, G. Hedenborg, A. Norman.
Evaluation of the lactulose/mannitol and 51Cr-Ethylenediaminetettraacetic Acid/14C-mannitol methods for the intestinal permeability.
Scand J Gastroenterol, 32 (1997), pp. 805-812
[32.]
H. Prytz, C. Benoni, C. Tagesson.
Does smoking tighten the gut?.
Scan J Gastroenterol, 24 (1989), pp. 1084-1088
[33.]
G.M. Robinson, H. Orrego, Y. Israel, P. Devenyi, B.M. Kapur.
Low-molecular weigth polyethylene glycol as a probe of gastrointestinal permeability after alcohol ingestion.
Dig Dis Sci, 26 (1981), pp. 971-977
[34.]
I. Bjanarson, K. Ward, T.J. Peters.
The leaky gut of alcoholism: possible route of entry for toxic compounds.
Lancet, 1 (1984), pp. 179-182
[35.]
A. Pfeiffer, T. Schmidt, N. Vidon, C. Pehl, H. Kaess.
Absorption of nutrient solution in chronic alcoholics without nutrient deficiencies and liver cirrhosis.
Scand J Gastroenterol, 27 (1992),
[36.]
A. Keshavarzian, J.Z. Fields, J. Vaeth, E.W. Holmes.
The differing effects of acute and chronic alcohol on gastric and intestinal permeability.
Am J Gastroenterol, 89 (1994), pp. 2205-2221
[37.]
D. Hollander.
Gastrointestinal complications of nonsteroidal anti-inflammatory drugs: prophilactic and therapeutic strategies.
Am J Med, 96 (1994), pp. 281
[38.]
L. Aabaken.
Small-bowell side-effects of non-steroidal anti-inflammatory drugs.
Eur J Gastroenterol Hepatol, 11 (1999), pp. 383-388
[39.]
I. Bjarnason, B. Fehily, P. Smethurst, I.S. Menzies, A.J. Levi.
Effects of nonsteroidal anti-inflammatory drugs on permeability of the small intestine in humans.
J Rheumatol, 19 (1992), pp. 83-84
[40.]
R.T. Jenkins, P.J. Rooney, D.B. Jones, J. Bienenstock, R.L. Gooddacre.
Increased intestinal permeability in patients with rheumatoid arthritis: a side effect of nonsteroidal anti-inflammatory drugs therapy.
Br J Rheumatol, 26 (1987), pp. 104-107
[41.]
I. Bjarnason, P. Williams, P. Smethurst, T.J. Peters, A.J. Lae.
Effect of nonsteroidal anti-inflammatory drugs and prostaglandin on the permeability of the human small intestine.
Gut, 27 (1986), pp. 1292-1297
[42.]
I. Bjarnason, B. Fehily, P. Smethurst, I.S. Menzies, A.J. Levi.
Importance of local versus systemic effects of non-steroidal antiinflammatory drugs in increasing small intestinal permeability in man.
Gut, 32 (1991), pp. 275-277
[43.]
G. Sigthorsson, J. Tibble, J. Hayllar, I. Menzies, A. Macpherson, R. Moots, et al.
Intestinal permeability and inflammation in patiens on NSAIDs.
Gut, 43 (1998), pp. 506-511
[44.]
G.R. Davies, D.S. Rampton.
The pro-drug sulindac may reduce the risk of intestinal damage associated with the use of conventional non-steroidal anti-inflammatory drugs.
Aliment Pharmacol Ther, 5 (1991), pp. 593-598
[45.]
A.P. Jenkins, D.R. Trew, B.J. Crump, W.S. Nukajam, J.A. Foley, I.S. Menzies, et al.
Do non-steroidal anti-inflammatory drugs increase colonic permeability?.
Gut, 32 (1991), pp. 66-69
[46.]
C. Tageson, A. Bengtsson.
Intestinal permeability to different size polythelene glycols in patients with rheumatoid arthritis.
Scand J Rheumatol, 12 (1983), pp. 124-128
[47.]
J. Keating, I. Bjarnasson, S. Somasundaram, A. Macpherson, N. Francis, A.B. Price, et al.
Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea.
Gut, 37 (1995), pp. 623-629
[48.]
S.G. Lim, S. Mezies, C.A. Lee, M.A. Johnson, R.E. Pounder.
Intestinal permeability and function in patients infected with human immunodeficiency virus.
Scand J Gastroenterol, 28 (1993), pp. 573-580
[49.]
R.E. Tepper, D. Simon, L.J. Brandt, R. Nutovis, M.J. Lee.
Intestinal permeability in patients infected with the human immunodeficiency virus.
Am J Gastroenterol, 89 (1994), pp. 878-882
[50.]
P. Pernet, D. Vittecoq, A. Kodjo, M.H. Randrianarisolo, L. Dumitresco, H. Blondon, et al.
Intestinal absortion and permeability in human immunodeficiency virus-infected patients.
Scand J Gastroenterol, 34 (1999), pp. 29-34
[51.]
T.R. Ziegler, R.J. Smith, O'Dwyer, R.H. Demling, D.W. Wilmore.
Increased intestinal permeability associated with infection in burn patients.
Arch Surg, 123 (1988), pp. 1313-1319
[52.]
E.A. Deitz.
Intestinal permeability is increased in burn patients shortly after injury.
Surgery, 102 (1990), pp. 411-412
[53.]
B. Langkamp-Henken, T.B. Donovan, L.M. Pate, C.D. Maull, K.A. Kudsk.
Increased intestinal permeability following blunt and penetrating trauma.
Crit Care Med, 23 (1995), pp. 660-664
[54.]
R.M.H. Roumen, T. Hendriks, R.A. Wevers, J.A. Goris.
Intestinal permeability after severe trauma and hemorrhagic shock is increased without relation to septic complications.
Arch Surg, 128 (1993), pp. 453-457
[55.]
S.K. Ohri, S. Somusundaram, Y. Koak, A. Macpherson, B.E. Keogh, K.M. Taylor, et al.
The effect of intestinal hypoperfusion on intestinal absorption and permeability during cardiopulmonary bypass.
Gastroenterology, 106 (1994), pp. 318-323
[56.]
F.K.S. Welsh, S.M. Farmery, K. MacLennan, M.B. Sheridan, G.R. Barclay, P.J. Guillou, et al.
Gut barrier function in malnourished patients.
Gut, 42 (1998), pp. 396-401
[57.]
D.R. Brewster, M.J. Manary, I.S. Menzies, E.V. O'Loughlin, R.L. Henry.
Increased permeability in kwashiorkor.
Arch Dis Child, 76 (1997), pp. 236-241
[58.]
M. Elia, A. Gore, R. Behrens.
Effect of total starvation and very low calorie diets on intestinal permeability in man.
Clin Sci, 73 (1987), pp. 205-210
[59.]
RRWJ Van Der Hulst, M.F. Von Meyenfeldt, B.K. Van Kreel, FBJM Thunnissen, R.J.M. Brummer, J.W. Arends, et al.
Gut permeability, intestinal morphology and nutritional depletion.
Nutrition, 14 (1998), pp. 1-6
[60.]
D.G. Maxton, R.P. Thompson, I.S. Menzies.
Intestinal malabsorption and hyperpermeability during enteral nutrition.
Clin Sci, 67 (1984), pp. 36A
[61.]
K.A. Illig, C.K. Ryan, D.J. Hardy, J. Rhodes, W. Locke, H.C. Sax.
Total parenteral nutrition-induced changes in gut function: atrophy alone is not the issue.
Surgery, 112 (1992), pp. 631-637
[62.]
P.C. Sedman, J. MacFie, M.D. Palmer, C.J. Mitchell, P.M. Sagar.
Preoperative total parenteral nutrition is not associated with mucosal atrophy or bacterial translocation in humans.
Br J Surg, 82 (1995), pp. 1663-1667
[63.]
B. Wallaert, J.F. Colombel, A. Adenis, X. Marchandise, R. Hallgren, A. Janin, et al.
Intestinal permeability in active pulmonary sarcoidosis.
Am Rev Respir Dis, 145 (1992), pp. 1440-1445
[64.]
J. Leclercq-Foucart, P. Forget, F. Sodoyez-Gouffaux, A. Zapitelli.
Intestinal Permability to 51CrEDTA in children with cystic fibrosis.
J Pediatr Gastroenterol Nutr, 5 (1986), pp. 384-387
[65.]
A. Bernard, P. Desreumeaux, D. Huglo, A. Hoorelbeke, A.B. Tonnel, B. Wallaert.
Increased intestinal permeability in bronchial asthma.
J Allergy Clin Immunol, 97 (1996), pp. 1173-1178
[66.]
I. Bjarnasson, S.K. Goolamali, A.J. Levi, T.L. Peters.
Intestinal permeability in patiens with atopic eczema.
Br J Dermatol, 112 (1985), pp. 291-297
[67.]
F. Andre, C. Andre, M. Feknous, L. Colin, S. Cavagna.
Digestive permeability to different-size molecules and to sodium cromoglycate in food allergy.
Allergy Proc, 12 (1991), pp. 293-298
[68.]
J.J.P. Schrander, R.W.M. Unsalan-Hooyen, P.P. Forest, J. Jansen.
(51Cr) EDTA intestinal permeability in children with cow's milk intolerance.
J Pediatr Gastroenterol Nutr, 10 (1990), pp. 189-192
[69.]
G.A. McGauley.
Abnormal intestinal permeability: an aetiological factor in chronic psychiatric disorders.
Br J Psychiatr, 151 (1987), pp. 704-705
[70.]
B.T. Cooper, S.O.N. Ukabam.
O'Brien IAD. Intestinal permeability in diabetic diarrhoea.
Diabetes Med, 4 (1987), pp. 49-52
[71.]
R.A. Erickson, R.M. Epsten.
Oral chenodeoxycholic acid increases small intestinal permeability to lactulose in humans.
Am J Gastroenterol, 83 (1988), pp. 541-544
[72.]
P.J. Selby, N. Lopes, J. Mundy, M. Crofts, J.L. Millar, T.J. McElwin.
Cyclohosphamide priming reduces intestinal damage in man following high dose melphalan chemotherapy.
Br J Cancer, 55 (1987), pp. 531-533
[73.]
G.R. Siber, R.J. Mayer, M.J. Levin.
Increased intestinal absorption of large molecules in patients after 5-flourouracil therapy for metastasic colon carcinoma.
Cancer Res, 40 (1980), pp. 3430-3436
[74.]
O. Oktedalen, O.C. Lunde, P.K. Opstad, L. Aabeken, K. Kvernebo.
Changes in the gastrointestinal mucosa after long-distance running.
Scand J Gastroenterol, 27 (1992), pp. 270-274
[75.]
J.B. Meddings.
Review article: intestinal permeability in Crohn's disease.
Aliment Pharmacol Ther, 11 (1997), pp. 47-56
[76.]
G. Olaison, R. Sjödahl, C. Tagesson.
Abnormal Intestinal Permeability in Crohn's Disease. A Possible Pathogenic Factor.
Scand J Gastroenterol, 25 (1990), pp. 321-328
[77.]
S. Imer, L. Franzen.
Increased absorption of polyethylene glycol 600 deposited in colon in active ulcerative colitis.
Gut, 34 (1993), pp. 509-513
[78.]
M.J. Zuckerman, M.T. Watts.
Intestinal permeability to 51Crethylenediaminetetraacetate in patients with ulcerative colitis.
Am J Gastroenterol, 88 (1993), pp. 1978-1981
[79.]
K. Teahon, P. Smethurst, A.J. Macpherson, A.J. Levi, I.S. Menzies, I. Bjarnasson.
Intestinal permeability in Crohn's disease and its relation to disease activity and relapse following treatment with elemental diet.
Eur J Gastroenterol Hepatol, 5 (1993), pp. 79-84
[80.]
K. Teahon, P. Smethurst, M. Pearson, A.J. Levi, I. Bjarnasson.
The effect of elemental diet on intestinal permeability and inflammation in Crohn's disease.
Gastroenterology, 101 (1991), pp. 84-89
[81.]
J. Wyatt, H. Volgelsang, W. Hübl, T. Waldhöer, H. Lochs.
Intestinal permeability and the prediction of relapse in Crohn's disease.
Lancet, 341 (1993), pp. 1437-1439
[82.]
D. Hollander.
Crohn's disease a permeability disorder of the tight junction?.
Gut, 29 (1988), pp. 1621-1624
[83.]
M. Malin, E. Isolauri, P. Pikkarainen, R. Karikoski, J. Isolauri.
Enhanced absorption of macromolecules. A secondary factor in Crohn's disease.
Dig Dis Sci, 41 (1996), pp. 1423-1428
[84.]
M. Peeters, B. Geypens, D. Claus, H. Nevens, Y. Ghoos, G. Verbeke, et al.
Clustering of increased small intestinal permeability in families with Crohn's disease.
Gastroenterology, 113 (1997), pp. 802-807
[85.]
D. Hollander.
Permeability in Crohn's disease: altered barrier functions in healthy relatives?.
Gastroenterology, 104 (1993), pp. 1848-1873
[86.]
P. Munkholm, E. Langholz, D. Hollander, K. Thornberg, M. Orhlom, K.D. Katz, et al.
Intestinal permeability in patients with Crohn's disease and ulcerative colitis and their firts degree relatives.
Gut, 35 (1994), pp. 68-72
[87.]
K. Teathon, P. Smethurst, A.J. Levi, I.S. Manzies, I. Bjarnasson.
Intestinal permeability in patients with Crohn's disease and their first degree relatives.
Gut, 33 (1992), pp. 320-323
[88.]
G.R. May, L.R. Sutherland, J.B. Meddings.
Is intestinal permeability really increased in relatives of patients with Crohn's disease?.
Gastroenterology, 104 (1993), pp. 1627-1632
[89.]
L. Pironi, M. Miglioli, E. Ruggeri, M.A. Dallasta, L. Ornigotti, D. Valpiani, et al.
Effect of non-steroidal anti-inflammatory drugs (NSAID) on intestinal permeability in first degree relatives of patients with Crohn's disease.
Gastroenterology, 102 (1992), pp. A679
[90.]
G. Olaison, R. Sjodahl, C. Tageson.
Decreased gastrointestinal absorption of different-size polyethylene glycols (PEG 1000) in Crohn's disease: a sign of jejunal abnormality.
Acta Chir Scand, 153 (1987), pp. 373-377
[91.]
G. Olaison, P. Leandersson, R. Sjodahl, C. Tageson.
Intestinal permeability to polyethylene glycol 600 in Crohn's disease. Perioperative determination in a defined segment of the small bowell.
Gut, 29 (1988), pp. 196-199
[92.]
K. Teathon, S. Somasundaram, T. Smith, I. Menzies, I. Bjarnason.
Assesing the site of increased intestinal permeability in coeliac and inflammatory bowel disease.
Gut, 38 (1996), pp. 864-869
[93.]
I. Bjarnason, D. Maxton, A.P. Reynolds, S. Catt, T.J. Peters, I.S. Menzies.
Comparison of Four markers of intestinal permeability in control subjects and patients with coeliac disease.
Scand J Gastroenterol, 29 (1994), pp. 630-639
[94.]
I. Cobden, R.J. Dickinson, J. Rothwell.
Axon ATR. Intestinal permeability assessed by excretion ratios of two molecules: results in coeliac disease.
Br Med J, 2 (1978), pp. 1060
[95.]
L.D. Juby, J. Rothwell.
Axon ATR. Cellobiose/mannitol sugar test-a sensitive tubeless test for coeliac disease: results on 1010 unselected patients.
Gut, 30 (1989), pp. 476-480
[96.]
I. Hamilton, I. Cobden, J. Rothwell.
Axon ATR. Intestinal permeability in coeliac disease: the response to gluten withdrawal and single-dose gluten challenge.
Gut, 23 (1982), pp. 202-210
[97.]
P.B. Bijlsma, R.A. Peeters, J.A. Groot, P.R. Dekker, J.A. Taminiau, R. Van Der Meer.
Differential in vivo and in vitro intestinal permeability to lactulose and mannitol in animals and humans: a hypothesis.
Gastroenterology, 108 (1995), pp. 687-696
[98.]
E. Smecuol, J.C. Bai, H. Vazquez, Z. Kogan, S. Niveloni, S. Pedreira, et al.
Gastrointestinal permeability in coeliac disease.
Gastroenterology, 112 (1997), pp. 1129-1136
[99.]
R.W. Parks, E.D.B. Clements, M.G. Smye, C. Pope, B.J. Rowlands, T. Diamond.
Intestinal barrier dysfunction in clinical and experimental obstructive jaundice and its reversal by internal biliary drainage.
Br J Surg, 83 (1996), pp. 1345-1349
[100.]
F.K.S. Welsh, C.W. Ramsden, K. MacLennan, M.B. Sheridan, G.R. Barclay, P.J. Guillou, et al.
Increased intestinal permeability and altered mucosal immunity in cholestatic jaundice.
Ann Surg, 227 (1998), pp. 205-212
[101.]
M.J. Zuckerman, M.T. Watts, B.D. Bhatt, H. Ho.
Intestinal permeability to [51Cr]EDTA in infectious diarrhea.
Dig Dis Sci, 38 (1993), pp. 1651-1657
[102.]
G. Parrilli, R. Cuoma, G. Nardone, G. Maio, C.M. Izzo, G. Budillon.
Investigation of intestine function during acute viral hepatitis using combined sugar oral load.
Gut, 28 (1987), pp. 1439-1444
[103.]
N. Pantzar, P.B.F. Bergqvist, M. Bugge, G. Olaison, G. Lundin, B. Jeppsson, et al.
Small intestinal absorption of polythylene glycol 400 to 1000 in the portacaval shunted Rat.
Hepatology, 21 (1995), pp. 1167-1173
[104.]
J.W. Alexander, S.T. Boyce, G.F. Babcock, L. Gianotti, M.D. Pack, D.L. Dunn, et al.
The process of microbial translocation.
Ann Surg, 212 (1990), pp. 496-510
[105.]
R.D. Berg.
Bacterial translocation from the gastrointestinal tract.
J Med, 23 (1992), pp. 217-244
[106.]
G. Budillón, G. Parrilli, M. Pacella, R. Cuomo, I.S. Menzies.
Investigation of intestine and liver function in cirrhosis using combined sugar oral loads.
J Hepatol, 1 (1985), pp. 513-524
[107.]
D.J. Bac, G.R. Swart, J.W.O. van den Berg.
Wilson JHP. Small bowel wall function in patients with advanced liver cirrhosis and portal hypertension: studies on permeability and luminal bacterial overgrowth.
Eur J Gastroenterol Hepatol, 5 (1993), pp. 383-387
[108.]
R. Hamdani, R. Chapparella, R.E. Stauber, S. Wood, D. Kramer, E. Rosemblum, et al.
Intestinal permeability as measured with polyethylene glycol 600 in patients with cirrhosis: clinical investigation.
Gastroenterology, 108 (1995), pp. A1079
[109.]
G. Ersöz, A. Aydin, S. Erdem, D. Yüksel, U. Akarca, K. Kumanlioglu.
Intestinal permeability in liver cirrhosis.
Eur J Gastroenterol Hepatol, 11 (1999), pp. 409-412
[110.]
B. Campillo, P. Pernet, P.N. Bories, J.P. Richardet, M. Devanley, C. Aussel.
Intestinal permeability in liver cirrhosis: relationship with severe septic complications.
Eur J Gastroenterol Hepatol, 11 (1999), pp. 755-759
[111.]
S. Pascual, J. Such, A. Esteban, F. Carnicer, J.M. Palazón, M. Pérez-Mateo.
Permeabilidad intestinal en la cirrosis: estudio de absorción de macromoléculas.
Gastroenterol Hepatol, 23 (2000), pp. A132
[112.]
S. Smale, J. Tibble, I. Bjarnasson.
Small intestinal permeability.
Curr Op Gastroenterol, 16 (2000), pp. 134-139
[113.]
J.E. Domínguez-Muñoz, J.A. Viedma, M. Pérez-Mateo, F. Carballo, MF. García.
La respuesta inflamatoria en al fase inicial de la pancreatitis aguda: relación con el comienzo y la gravedad de la enfermedad.
Rev Esp Enferm Digest, 3 (1995), pp. 236-246
[114.]
J.D. Wig, R. Kochhar, J.D. Ray, D.V.K. Rao, N.M. Gupta, N.K. Ganguly.
Endotoxemia predicts outcome in acute pancreatitis.
J Clin Gastroenterol, 26 (1998), pp. 121-124
[115.]
J. Martínez, C. Muñoz, J. Sánchez-Payá, M. López-Quemada, C. Quílez, JM. Palazón.
Estudio sobre el valor de la endotoxina en el pronóstico de la pancreatitis aguda.
Rev Esp Enferm Digest, 10 (1998), pp. 761
[116.]
C.M. Ryan, J. Schmidt, K. Lewandroski, C.C. Compton, D.W. Rattner, A.L. Warshaw, R.G. Tompkins.
Gut macromolecular permeability in pancreatitis correlates with severity of disease in rats.
Gastroenterology, 104 (1993), pp. 890-895
[117.]
X.D. Wang, Q. Wang, R. Andersson, I. Ihse.
Alterations in intestinal function in acute pancreatitis in an experimental model.
Br J Surg, 83 (1996), pp. 1537-1542
[118.]
B.J. Ammori, P.C. Leeder, R.F. King, G.R. Barclay, I.G. Martin, M. Larvin, et al.
Early increase in intestinal permeability in patients with severe acute pancreatitis: correlation with endotoxemia, organ failure and mortality.
J Gastrointest Surg, 3 (1999), pp. 252-262
[119.]
S. Smale, J. Tibble, I. Bjarnason.
Small intestinal permeability.
Eur J Gastroenterol Hepatol, 16 (2000), pp. 134-139
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