array:23 [ "pii" => "S002577530071253X" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71253-X" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71253" "copyright" => "Elsevier España, S.L.. Todos los derechos reservados" "copyrightAnyo" => "2000" "documento" => "article" "crossmark" => 0 "subdocumento" => "exm" "cita" => "Med Clin. 2000;114:235-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1235 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 1083 "PDF" => 146 ] ] "itemSiguiente" => array:18 [ "pii" => "S0025775300712541" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71254-1" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71254" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Med Clin. 2000;114:237-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1340 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 1205 "PDF" => 129 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Si son abstemios, mejor" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "237" "paginaFinal" => "238" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Miguel Ángel Martínez-González, Jokin de Irala-Estévez, Marta Pérez-Gaspar, Pilar Gual" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Miguel" "apellidos" => "Ángel Martínez-González" ] 1 => array:2 [ "nombre" => "Jokin" "apellidos" => "de Irala-Estévez" ] 2 => array:2 [ "nombre" => "Marta" "apellidos" => "Pérez-Gaspar" ] 3 => array:2 [ "nombre" => "Pilar" "apellidos" => "Gual" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300712541?idApp=UINPBA00004N" "url" => "/00257753/0000011400000006/v1_201307291356/S0025775300712541/v1_201307291356/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0025775300712528" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71252-8" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71252" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Med Clin. 2000;114:227-34" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 11659 "formatos" => array:3 [ "EPUB" => 12 "HTML" => 10873 "PDF" => 774 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "La vía JAK-STAT de señalización intracelular y su repercusión en oncogénesis, inmunomodulación y desarrollo" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "227" "paginaFinal" => "234" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Rafael F. Duarte, David A. Frank" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Rafael F." "apellidos" => "Duarte" ] 1 => array:2 [ "nombre" => "David A." "apellidos" => "Frank" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300712528?idApp=UINPBA00004N" "url" => "/00257753/0000011400000006/v1_201307291356/S0025775300712528/v1_201307291356/es/main.assets" ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Antiagregante de elección para prevenir la tromboembolia en los pacientes con prótesis valvulares tratados con anticoagoluantes orales" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "235" "paginaFinal" => "236" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Xavier Carbonell, Antònia Agustí" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Xavier" "apellidos" => "Carbonell" ] 1 => array:3 [ "nombre" => "Antònia" "apellidos" => "Agustí" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "<span class="elsevierStyleItalic">Fundació Institut Català de Farmacologia. Servei de Farmacologia Clínica. Hospitals Vall d'Hebron. Barcelona</span>" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dra. A. Agustí. Fundació Institut Català de Farmacologia. Servei de Farmacologia Clínica. Hospitals Vall d'Hebron. Passeig Vall d'Hebron, 119-129. 08035 Barcelona." ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1999-09-09" "fechaAceptado" => "1999-12-16" "bibliografia" => array:2 [ "titulo" => "Referencias Bibliográficas" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:12 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Turpie AGG. Antithrombotic therapy in patients with mecanical and biological prosthetic heart valves" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.D. Stein" 1 => "J.S. Alpert" 2 => "J.E. Dalen" 3 => "D. Horstkotte" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1998" "volumen" => "114" "numero" => "Supl" "paginaInicial" => "602" "paginaFinal" => "610" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Guidelines for prevention of thromboembolic events in valvular heart disease" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Study Group of The Working Group on Valvular Heart Disease of the European Society of Cardiology" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Heart J" "fecha" => "1995" "volumen" => "16" "paginaInicial" => "1320" "paginaFinal" => "1330" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8746900" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on management of patients with valvular heart disease)" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "ACC/AHA Guidelines for the management of patients with valvular heart disease" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "1998" "volumen" => "32" "paginaInicial" => "1486" "paginaFinal" => "1588" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9809971" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Twelve-year comparison of a Bjork-Shiley mechanical heary valve with porcine bioprostheses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P. Bloomfield" 1 => "D.J. Wheatley" 2 => "R.J. Prescott" 3 => "H.C. Miller" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199102283240901" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1991" "volumen" => "324" "paginaInicial" => "573" "paginaFinal" => "579" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1992318" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The efficacy and safety of combination warfarin and ASA therapy: a systematic review of the literature and update of guidelines" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Loewen" 1 => "R. Sunderji" 2 => "K. Gin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Can J Cardiol" "fecha" => "1998" "volumen" => "14" "paginaInicial" => "717" "paginaFinal" => "726" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9627529" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.G.G. Turpie" 1 => "M. Gent" 2 => "A. Laupacis" 3 => "Y. Latour" 4 => "J. Gunstensen" 5 => "F. Basile" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199308193290802" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1993" "volumen" => "329" "paginaInicial" => "524" "paginaFinal" => "529" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8336751" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Aspirin and prophylaxis for thromboembolic complications in patients with substitute heart valves" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Altman" 1 => "F. Boullon" 2 => "J. Rouvier" 3 => "R. Raca" 4 => "L. De la Fuente" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1976" "volumen" => "72" "paginaInicial" => "127" "paginaFinal" => "129" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1084448" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Trial of combined warfarin plus dipyridamole or Aspirin therapy in prosthetic heart valve replacement: danger of Aspirin compared with dipyridamole" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.H. Chesebro" 1 => "V. Fuster" 2 => "L.R. Elveback" 3 => "D.C. McGoon" 4 => "J.R. Pluth" 5 => "F.J. Puga" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Cardiol" "fecha" => "1983" "volumen" => "51" "paginaInicial" => "1537" "paginaFinal" => "1541" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6342354" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a metaanalysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.C. Caperelli" 1 => "L.D. Fiore" 2 => "M.T. Brophy" 3 => "D. Deykin" 4 => "J. Lau" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am Heart J" "fecha" => "1995" "volumen" => "130" "paginaInicial" => "547" "paginaFinal" => "552" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7661074" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low intensity oral anticoagulation plus low dose aspirin versus high-intensity oral anticoagulants alone: a randomized trial in patients with mechanical prosthetic heart valves" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S.S. Meschengieser" 1 => "C.G. Fondevila" 2 => "J. Frontroth" 3 => "M.T. Santarelli" 4 => "M.A. Lazzari" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0022-5223(97)70264-2" "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1997" "volumen" => "113" "paginaInicial" => "910" "paginaFinal" => "916" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9159625" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of high-dose with low-dose aspirin in patients with mechanical heart valve replacement treated with oral anticoagulant" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Altman" 1 => "J. Rouvier" 2 => "E. Gurfinkel" 3 => "A. Scazziora" 4 => "A.G. Turpie" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1996" "volumen" => "94" "paginaInicial" => "2113" "paginaFinal" => "2116" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8901660" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of dipyridamole in combination with anticoagulant therapy on survival and thromboembolic events in patients with prosthetic heart valves: a metaanalysis of the randomized trials" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "H. Pouleur" 1 => "M. Buyse" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0022-5223(95)70243-1" "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1995" "volumen" => "110" "paginaInicial" => "463" "paginaFinal" => "472" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7637364" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/00257753/0000011400000006/v1_201307291356/S002577530071253X/v1_201307291356/es/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/00257753/0000011400000006/v1_201307291356/S002577530071253X/v1_201307291356/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S002577530071253X?idApp=UINPBA00004N" ]
Información de la revista
Compartir
Descargar PDF
Más opciones de artículo
Antiagregante de elección para prevenir la tromboembolia en los pacientes con prótesis valvulares tratados con anticoagoluantes orales
Fundació Institut Català de Farmacologia. Servei de Farmacologia Clínica. Hospitals Vall d'Hebron. Barcelona