Originales
Factores asociados al desarrollo de atopia en adultos jóvenes
Factors associated to the development of atopy in young Spanish adults
Xavier Cortèsa, Joan B. Sorianoa, Jordi Sunyera,
, Jesús Martínez-Moratallab, Nerea Muniozgorenc, José Antonio Maldonadod, Ramón Quiróse, Josep M.a Antóa
Autor para correspondencia
jsunyer@imim.es
Correspondencia: Unitat de Recerca Respiratòria i Ambiental. Institut Municipal d#Xx0027;Investigació Mèdica. Doctor Aiguader, 80. 08003 Barcelona.
Correspondencia: Unitat de Recerca Respiratòria i Ambiental. Institut Municipal d#Xx0027;Investigació Mèdica. Doctor Aiguader, 80. 08003 Barcelona.
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IMIM. Barcelona</span>" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff00005" ] 1 => array:3 [ "entidad" => "<span class="elsevierStyleItalic">Unidad de Neumología. Hospital General de Albacete</span>" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff00010" ] 2 => array:3 [ "entidad" => "<span class="elsevierStyleItalic">Dirección General de Salud de Vizcaya. Bilbao</span>" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff00015" ] 3 => array:3 [ "entidad" => "<span class="elsevierStyleItalic">Servicio de Neumología. Hospital General de Huelva</span>" "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff00020" ] 4 => array:3 [ "entidad" => "<span class="elsevierStyleItalic">Dirección de Salud Pública. Consejería de Sanidad de Asturias. Oviedo</span>" "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "aff00025" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Unitat de Recerca Respiratòria i Ambiental. Institut Municipal d#Xx0027;Investigació Mèdica. Doctor Aiguader, 80. 08003 Barcelona." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Factors associated to the development of atopy in young Spanish adults" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1999-09-17" "fechaAceptado" => "1999-12-14" "PalabrasClave" => array:1 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec221285" "palabras" => array:4 [ 0 => "Atopia" 1 => "Educación" 2 => "Familia" 3 => "Infecciones respiratorias" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Determinar los factores de riesgo para el desarrollo de atopia en adultos jóvenesespañoles.</p> <span class="elsevierStyleSectionTitle">PoblaciÓn y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio de casos y controles sobre casos prevalentes basado en población generalde edades comprendidas entre 20 y 44 años. Fue estudiada una muestra aleatoria y representativade los adultos jóvenes españoles participantes en el European Community RespiratoryHealth Survey (ECRHS) (n = 16.884), a partir de la cual se seleccionó una submuestra tambiénaleatoria del 20% de los sujetos, que realizaron un cuestionario corto sobre síntomas respiratoriosy a los cuales les fue evaluada la atopia. Definimos atopia como la existencia de cifras detectablesde IgE específica en suero contra los siguientes aeroalergenos comunes: pelo de gato, Cladosporiumherbarum, Dermathophagoides pteronyssinus, Parietaria judaica y Phleum pratense.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Además del sexo masculino y las edades tempranas, alergia materna (OR = 1,63;IC del 95% = 1,11-2,40), tener algún hermano alérgico (OR = 1,40; IC del 95% = 1,06-1,90)y un nivel educacional elevado (OR = 1,69; IC del 95% = 1,22-2,34) se asociaron a la presenciade cifras elevadas de IgE específicas. Además, tener hermanos mayores, especialmente sison varones, parece tener un efecto protector contra el desarrollo de atopia, aunque no de formaestadísticamente significativa; igualmente, haber tenido un pájaro en casa aumentaba elriesgo, aunque esta asociación tampoco fue significativa.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Además de las variables familiares que indican tanto factores genéticos como ambientales,el nivel educativo parece tener algún grado de asociación con la atopia, indicando quelas variables relacionadas con el estilo de vida intervienen de forma importante en su desarrollo.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To determine the risk factors for the development of atopy in Spanish young adults.</p> <span class="elsevierStyleSectionTitle">Subjets and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Case-control study over prevalent cases. Carried out in general populationbetween the ages of 20 to 44 years old. Spanish participants of the ECRHS, a ramdom representativesample of Spanish young adults (n = 16,884), and a 20% randomised subsamplemade by those who answered to a short respiratory questionnaire and had atopy assessed, wasstudied. Atopy was defined as having serum specific IgE positivity to the following aeroallergnes:cat dander, Cladosporium herbarum, Dermatophagoides pteronyssinus, Parietaria judaicaand Phleum pratense.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Several factors had a statistically significant effect. In addition to male gender and lowerage, maternal allergy (OR = 1.63; 95% CI = 1.11-2.40), having allergic siblings (OR =1.40; 95% CI = 1.06-1.90) and a higher educational level (OR = 1.69; 95% CI = 1.22-2.34)were associated with the presence of high levels of specific IgE in our sample. Moreover, havinghad older siblings, especially older brothers appears to be a protective factor to the developmentof atopy but not in a statistically significant way, while having had pet birds duringchildhood appears to enhance the risk.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">In addition to the familial variables that indicates both environmental and geneticfactors, educational level seems to have low degree of association with atopy; this featureshows that variables related with life style are involved in atopy development.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias Bibliográficas" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:38 [ 0 => array:3 [ "identificador" => "bib00005" "etiqueta" => "1." 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| 2017 Agosto | 5 | 6 | 11 |
| 2017 Julio | 7 | 6 | 13 |
| 2017 Junio | 14 | 3 | 17 |
| 2017 Mayo | 12 | 3 | 15 |
| 2017 Abril | 9 | 2 | 11 |
| 2017 Marzo | 23 | 3 | 26 |
| 2017 Febrero | 10 | 0 | 10 |
| 2017 Enero | 7 | 1 | 8 |
| 2016 Diciembre | 26 | 6 | 32 |
| 2016 Noviembre | 24 | 0 | 24 |
| 2016 Octubre | 41 | 1 | 42 |
| 2016 Septiembre | 20 | 2 | 22 |
| 2016 Agosto | 9 | 0 | 9 |
| 2016 Julio | 20 | 1 | 21 |
| 2016 Junio | 29 | 1 | 30 |
| 2016 Mayo | 22 | 0 | 22 |
| 2016 Abril | 20 | 3 | 23 |
| 2016 Marzo | 34 | 0 | 34 |
| 2016 Febrero | 18 | 3 | 21 |
| 2016 Enero | 19 | 0 | 19 |
| 2015 Diciembre | 15 | 0 | 15 |
| 2015 Noviembre | 24 | 0 | 24 |
| 2015 Octubre | 17 | 0 | 17 |
| 2015 Septiembre | 22 | 0 | 22 |
| 2015 Agosto | 15 | 0 | 15 |
| 2015 Julio | 16 | 0 | 16 |
| 2015 Junio | 9 | 0 | 9 |
| 2015 Mayo | 20 | 0 | 20 |
| 2015 Abril | 16 | 0 | 16 |
| 2015 Marzo | 16 | 0 | 16 |
| 2015 Febrero | 11 | 0 | 11 |
| 2015 Enero | 21 | 0 | 21 |
| 2014 Diciembre | 17 | 0 | 17 |
| 2014 Noviembre | 4 | 0 | 4 |
| 2014 Octubre | 11 | 0 | 11 |
| 2014 Septiembre | 11 | 0 | 11 |
| 2014 Agosto | 10 | 0 | 10 |
| 2014 Julio | 3 | 0 | 3 |
| 2014 Junio | 8 | 0 | 8 |
| 2014 Mayo | 7 | 0 | 7 |
| 2014 Abril | 10 | 0 | 10 |
| 2014 Marzo | 1 | 0 | 1 |
| 2014 Febrero | 1 | 0 | 1 |
| 2014 Enero | 2 | 0 | 2 |
| 2013 Diciembre | 4 | 0 | 4 |
| 2013 Noviembre | 5 | 0 | 5 |
| 2013 Octubre | 9 | 0 | 9 |
| 2013 Septiembre | 6 | 0 | 6 |
| 2013 Agosto | 2 | 0 | 2 |
| 2000 Febrero | 634 | 0 | 634 |
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