metricas
covid
Buscar en
Medicina Clínica Práctica
Toda la web
Inicio Medicina Clínica Práctica Idiopathic basal ganglia calcification – Fahr's syndrome
Información de la revista
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Images in medicine
Open Access
Idiopathic basal ganglia calcification – Fahr's syndrome
Calcinosis bilateral estriato-pálido-dentada - Síndrome de Fahr
Visitas
1883
Gonçalo Miranda
Autor para correspondencia
goncaloflmiranda@gmail.com

Corresponding author.
, Maria Inês Gonçalves, Paula Perestrelo, Renato Gonçalves, Rosa Ballesteros
Serviço de Medicina Interna, Centro Hospitalar Universitário Cova da Beira, Quinta do Alvito, 6200-251 Covilhã, Portugal
Este artículo ha recibido

Under a Creative Commons license
Información del artículo
Texto completo
Bibliografía
Descargar PDF
Estadísticas
Figuras (3)
Mostrar másMostrar menos
Texto completo

Idiopathic basal ganglia calcification or Fahr's syndrome is a rare neurological disease characterized by the presence of deposits of calcium in the basal ganglia and other areas of the brain that control movements including the thalamus, dentate nucleus, cerebral cortex, cerebellum, subcortical white matter, and hippocampus.1

We report a case of a 78-year-old woman with history of arterial hypertension, dyslipidemia and major depressive disorder. A computed tomography of the brain was performed and shows extensive coarse calcifications involving the infra and supratentorial white matter and the basal ganglia. Other causes of brain calcification were excluded and the diagnosis of Fahr's syndrome was made.

The images are characteristic of Fahr's syndrome. We observe extensive and relatively typical distribution of calcification in basal ganglia and thalami (Fig. 1) and symmetrical dense calcific foci in the dentate nuclei (Fig. 2). Calcification can also be found in corona radiata and subcortical white matter (Fig. 3).

Figure 1
(0.07MB).
Figure 2
(0.07MB).
Figure 3
(0.06MB).

Clinical manifestations typically include movement disorders or neuropsychiatric manifestations.1 However, the presence of calcifications in asymptomatic individuals is possible. In the clinical case presented, the only manifestation is depression, an infrequent presentation.2

References
[1]
S. Saleem, H.M. Aslam, M. Anwar, S. Anwar, M. Saleem, A. Saleem, et al.
Fahr's syndrome: literature review of current evidence.
Orphanet J Rare Dis, 8 (2013), pp. 156
[2]
G. Konstantinou, A. Stavrinou, S. Mylona, G. Paschalakis, P. Vasilopoulou.
Basal ganglia calcification: a case report of Fahr disease with pure psychiatric symptoms.
J Psychiatr Pract, 25 (2019), pp. 391-394
Copyright © 2020. The Authors
Descargar PDF
Opciones de artículo
Herramientas
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos