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Perfiles de resistencia y factores de riesgo de microorganismos resistentes en bacteriemia de origen abdominal
Resistance profiles and risk factors of resistant microorganisms in bacteraemia of abdominal origin
J. Martín Jaramagoa,
Autor para correspondencia
jmartinjaramago@gmail.com

Autora para correspondencia.
, R. Armero Ibáñeza, J.J. Camarena Miñanab, M. Morales Suárez-Varelac,d
a Servicio de Anestesiología y Reanimación, Hospital Universitario Dr. Peset, Valencia, España
b Servicio de Microbiología, Hospital Universitario Dr. Peset, Valencia, España
c Departamento de Medicina Preventiva y Salud Pública, Universidad de Valencia, Valencia, España
d CIBER Epidemiología y Salud Pública (CIBERESP), España
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Seg&#250;n el &#250;ltimo informe de la OMS&#44; la resistencia antibi&#243;tica es un serio problema de salud p&#250;blica mundial&#44; que aumenta la estancia hospitalaria&#44; los costes sanitarios y es causa de morbimortalidad de los pacientes con bacteriemia<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">8</span></a>&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">El origen nosocomial o asociado a cuidados sanitarios de la bacteriemia y la administraci&#243;n de antibi&#243;tico previo son factores de riesgo asociados a la presencia de microorganismos resistentes<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">9&#44;10</span></a>&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Conocer actualmente los microorganismos causantes de la bacteriemia en esta selecci&#243;n de pacientes en nuestro medio y su perfil de sensibilidad y resistencia as&#237; como la relaci&#243;n con estos 2 factores de riesgo conocidos&#44; puede ser relevante en la eficacia del tratamiento antimicrobiano emp&#237;rico inicial&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Los objetivos de nuestro estudio son describir el perfil de resistencia de los microorganismos a los antimicrobianos en pacientes con bacteriemia de origen abdominal y determinar si la infecci&#243;n nosocomial o asociada a cuidados sanitarios y la administraci&#243;n de antibi&#243;tico previo son factores de riesgo para el aislamiento de microorganismos resistentes en esta selecci&#243;n de pacientes&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material y m&#233;todos</span><p id="par0030" class="elsevierStylePara elsevierViewall">Se realiza un estudio epidemiol&#243;gico cl&#237;nico&#44; observacional&#44; concretamente de cohorte retrospectiva de todos los pacientes adultos ingresados a cargo del Servicio de Cirug&#237;a General y Servicio de Digestivo en un hospital universitario&#44; 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Durante el periodo estudiado&#44; desde el 1 de enero de 2011 al 31 de diciembre de 2013 registr&#243;&#58; 25&#46;140 ingresos en 2011&#44; 24&#46;585 ingresos en 2012 y 25&#46;466 ingresos en 2013&#44; y se realizaron 18&#46;925 intervenciones quir&#250;rgicas en 2011&#44; 18&#46;744 en 2012 y 20&#46;223 en 2013&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Este estudio se realiz&#243; seg&#250;n la Declaraci&#243;n de Helsinki de la Asociaci&#243;n M&#233;dica Mundial sobre principios &#233;ticos para las investigaciones m&#233;dicas en seres humanos y fue aprobado por el Comit&#233; &#201;tico de Investigaci&#243;n Cl&#237;nica del hospital&#46; &#40;C&#243;digo Ceic&#46; 33&#47;14&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Se ha considerado criterios microbiol&#243;gicos&#44; por lo que se define bacteriemia como la presencia de bacterias en sangre que se pone de manifiesto por el aislamiento de estas en los hemocultivos<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">11</span></a>&#46; El t&#233;rmino fungemia se utiliza para designar la presencia de hongos en la sangre<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">11</span></a>&#46; Se excluyeron las bacteriemias y las fungemias cuyo foco es la peritonitis bacteriana espont&#225;nea&#44; por tratarse de una entidad que tiene lugar en una poblaci&#243;n con una afecci&#243;n espec&#237;fica y cuya flora microbiana tambi&#233;n es diferente&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Para la recogida de la muestra se ha seguido un procedimiento combinado revisando la informaci&#243;n de los pacientes del Servicio de Microbiolog&#237;a y su situaci&#243;n y evoluci&#243;n cl&#237;nica a trav&#233;s de la historia cl&#237;nica&#44; permiti&#233;ndonos reconstruir una cohorte retrospectiva&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Seg&#250;n el protocolo de nuestro hospital&#44; los hemocultivos se solicitaron a criterio del facultativo responsable&#44; cuando el paciente present&#243; fiebre<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>38<span class="elsevierStyleHsp" style=""></span>&#176;<span class="elsevierStyleSmallCaps">C</span> o existi&#243; sospecha cl&#237;nica de bacteriemia y antes de iniciar el tratamiento antibi&#243;tico emp&#237;rico&#46; La forma de extraer los hemocultivos se realiz&#243; seg&#250;n las <span class="elsevierStyleItalic">Recomendaciones de la Sociedad Espa&#241;ola de Enfermedades Infecciosas y Microbiolog&#237;a Cl&#237;nica</span> para extracci&#243;n de hemocultivos<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">12</span></a>&#46; Cuando en los hemocultivos crec&#237;a un microorganismo coagulasa negativo o un microorganismo contaminante de la piel&#44; se consider&#243; hemocultivo positivo solamente si crec&#237;an estos en 2 de las 2 muestras recogidas&#44; o en 2 de las 3 muestras recogidas&#46; Los otros casos se consideraron hemocultivos contaminados y fueron excluidos del estudio&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">El diagn&#243;stico del foco infeccioso primario se determin&#243; seg&#250;n el diagn&#243;stico recogido en la historia cl&#237;nica por el facultativo responsable&#44; basado en un diagn&#243;stico cl&#237;nico y apoyado por cultivos microbiol&#243;gicos cuando se consider&#243; necesario&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">De cada paciente se recogieron datos epidemiol&#243;gicos&#44; diagn&#243;stico principal durante el ingreso en el que tuvo lugar la bacteriemia&#44; enfermedad asociada y resultado completo de los hemocultivos&#44; incluyendo antibiograma y&#47;o antifungigrama&#46; Se recogieron tambi&#233;n los resultados de una segunda o tercera bacteriemia durante el mismo ingreso hospitalario y de otra bacteriemia cuando tuvo lugar en otro reingreso hospitalario cuyo diagn&#243;stico principal tambi&#233;n fue una infecci&#243;n de origen abdominal durante el periodo estudiado&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Se consider&#243; un microorganismo resistente cuando la concentraci&#243;n m&#237;nima inhibitoria determinada en el laboratorio a partir de la cepa era igual o superior a los campos de sensibilidad seg&#250;n los criterios del Clinical and Laboratory Standards Institute<a class="elsevierStyleCrossRefs" href="#bib0190"><span class="elsevierStyleSup">13&#44;14</span></a>&#46; Se definen como <span class="elsevierStyleItalic">Staphylococcus aureus &#40;S&#46; aureus&#41;</span> resistentes a meticilina las cepas para las que la correspondiente concentraci&#243;n m&#237;nima inhibitoria de oxacilina es<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>4<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#46; Un microorganismo se consider&#243; productor de betalactamasas de espectro extendido &#40;BLEE&#41; cuando se confirm&#243; mediante la t&#233;cnica de difusi&#243;n con disco la resistencia o disminuci&#243;n de los halos de inhibici&#243;n de algunos o todos los sustratos y el efecto sin&#233;rgico producido entre las cefalosporinas de espectro ampliado y el &#225;cido clavul&#225;nico<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">15</span></a>&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Se clasificaron las bacteriemias en comunitarias&#44; asociadas a cuidados sanitarios o nosocomiales<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a>&#46; Se consider&#243; bacteriemia comunitaria aquella que tiene su origen en la comunidad y es detectada dentro de las primeras 48<span class="elsevierStyleHsp" style=""></span>h de hospitalizaci&#243;n&#44; no mediando durante ese periodo ninguna actividad asistencial que pueda haberla inducido&#46; Bacteriemia relacionada con los cuidados sanitarios&#58; bacteriemia secundaria a un procedimiento diagn&#243;stico o terap&#233;utico realizado de forma ambulatoria&#44; bacteriemia en pacientes ambulatorios portadores de sondas urinarias y cat&#233;teres vasculares intravenosos&#44; bacteriemia en pacientes en hemodi&#225;lisis cr&#243;nica y en di&#225;lisis peritoneal y bacteriemia en pacientes ingresados en residencias de ancianos y en centros de larga estancia&#46; Y bacteriemias de origen nosocomial&#44; aquella que tiene lugar despu&#233;s de las primeras 48<span class="elsevierStyleHsp" style=""></span>h del ingreso hospitalario&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Se consider&#243; terapia antibi&#243;tica previa como el uso de antibi&#243;tico en los 3 meses anteriores<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">10</span></a>&#46; La duraci&#243;n del tratamiento antibi&#243;tico fue a criterio del facultativo responsable&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Una vez estudiados los perfiles de resistencia de los principales microorganismos implicados en la bacteriemia de origen abdominal en esta selecci&#243;n de pacientes que constituyeron la cohorte&#44; se estudi&#243; si exist&#237;a relaci&#243;n entre la administraci&#243;n previa de antibi&#243;tico y la presencia de microorganismos resistentes y entre el lugar de adquisici&#243;n de la bacteriemia y la presencia de microorganismos resistentes&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Del sistema de informaci&#243;n de laboratorio del Servicio de Microbiolog&#237;a Cl&#237;nica&#44; se seleccionaron todos los pacientes con hemocultivos positivos&#44; entre el 1 de enero de 2011 y el 31 de diciembre de 2013&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">El proceso de selecci&#243;n fue de la siguiente manera&#58; Se revisaron 2&#46;598 muestras de sangre en las que crec&#237;a alg&#250;n microorganismo&#44; obtenidas durante los a&#241;os 2011-2013&#46; Se eliminaron las muestras repetidas&#44; se adjudicaron estas muestras a los pacientes y se eliminaron los hemocultivos contaminados&#44; quedando 1&#46;245 pacientes con hemocultivos positivos&#46; De estos&#44; se seleccionaron aquellos cuyo foco infeccioso fue de origen abdominal&#44; 213 pacientes&#46; Y se elimin&#243; a uno por ser menor de 18 a&#241;os&#58; 212 pacientes adultos con bacteriemia cuyo foco infeccioso fue de origen abdominal&#46; Se realiz&#243; una base de datos con la edad y sexo de los pacientes&#44; diagn&#243;stico de la infecci&#243;n abdominal y resultado de todos los hemocultivos obtenidos incluyendo resultado completo de cada antibiograma correspondiente a cada hemocultivo&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">An&#225;lisis estad&#237;stico</span><p id="par0100" class="elsevierStylePara elsevierViewall">El an&#225;lisis estad&#237;stico se realiz&#243; con el programa inform&#225;tico SPSS&#44; versi&#243;n 20&#46;0 &#40;SPSS&#44; Inc&#46;&#44; Chicago&#44; IL&#44; EE&#46; UU&#46;&#41;&#46; La descripci&#243;n de las variables continuas se expres&#243; mediante la media<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>desviaci&#243;n est&#225;ndar e intervalos de confianza al 95&#37; &#40;IC 95&#37;&#41;&#46; Las variables cualitativas se expresaron mediante proporciones &#40;&#37;&#41;&#46; Se utiliz&#243; el test chi cuadrado al 95&#37; de confianza para determinar si exist&#237;a relaci&#243;n entre las variables estudiadas y la presencia de microorganismos resistentes&#46; El valor de p<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>0&#44;05 se consider&#243; estad&#237;sticamente significativo&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Resultados</span><p id="par0105" class="elsevierStylePara elsevierViewall">Se seleccionaron 212 pacientes con bacteriemias y&#47;o fungemias cuyo foco infeccioso primario fue de origen abdominal&#44; lo que supone una incidencia del 17&#37; de todos los pacientes con bacteriemia y&#47;o fungemia durante el periodo estudiado&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">Se presenta una mayor prevalencia de varones &#40;59&#37;&#41; frente a mujeres &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#44; pero no hay diferencia estad&#237;sticamente significativa en relaci&#243;n con la edad &#40;siendo la edad media de 71<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15 a&#241;os&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0115" class="elsevierStylePara elsevierViewall">La colangitis fue la patolog&#237;a m&#225;s com&#250;nmente asociada&#44; seguida de colecistitis y de pancreatitis &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabla 2</a>&#41;&#46; La patolog&#237;a asociada de los pacientes se muestra en la <a class="elsevierStyleCrossRef" href="#tbl0015">tabla 3</a>&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0120" class="elsevierStylePara elsevierViewall">En global&#44; los bacilos gramnegativos fueron los microorganismos m&#225;s com&#250;nmente implicados en las bacteriemias de estos pacientes&#44; y de ellos el m&#225;s frecuente fue <span class="elsevierStyleItalic">Escherichia coli &#40;E&#46; coli&#41;</span> seguido de <span class="elsevierStyleItalic">Klebsiella</span> spp&#46; De los grampositivos destacan los estafilococos coagulasa negativos &#40;SCN&#41; y los enterococos&#46; De los hongos&#44; <span class="elsevierStyleItalic">Candida</span> no albicans resultaron m&#225;s frecuentes que <span class="elsevierStyleItalic">Candida albicans &#40;C&#46; albicans&#41;</span>&#46; Se identifica un predominio&#44; estad&#237;sticamente significativo&#44; de microorganismos causantes de la bacteriemia gramnegativos &#40;79&#44;24&#37;&#41; frente a grampositivos &#40;41&#44;03&#37;&#41;&#44; anaerobios &#40;2&#44;83&#37;&#41; y hongos &#40;11&#44;79&#37;&#41;&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Ciento setenta y dos pacientes presentaron una bacteriemia monomicrobiana y 40 una bacteriemia polimicrobiana &#40;18&#44;86&#37;&#41; &#40;tabla 4&#41;&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0130" class="elsevierStylePara elsevierViewall">Las resistencias de <span class="elsevierStyleItalic">S&#46; aureus</span>&#44; SCN&#44; <span class="elsevierStyleItalic">Enterococcus faecalis &#40;E&#46; faecalis&#41;</span>&#44; <span class="elsevierStyleItalic">Enterococcus faecium &#40;E&#46; faecium&#41;</span>&#44; <span class="elsevierStyleItalic">E&#46; coli</span>&#44; <span class="elsevierStyleItalic">Klebsiella pneumoniae &#40;K&#46; pneumoniae&#41;</span>&#44; <span class="elsevierStyleItalic">Pseudomonas aeruginosa &#40;P&#46; aeruginosa&#41;</span> y <span class="elsevierStyleItalic">Acinetobacter baumanii &#40;A&#46; baumanii&#41;</span> se muestran en las <a class="elsevierStyleCrossRefs" href="#tbl0025">tablas 5&#8211;8</a> respectivamente&#46; Las resistencias de <span class="elsevierStyleItalic">C&#46; albicans</span> y <span class="elsevierStyleItalic">Candida</span> no albicans se muestran en la <a class="elsevierStyleCrossRef" href="#tbl0045">tabla 9</a>&#46;</p><elsevierMultimedia ident="tbl0025"></elsevierMultimedia><elsevierMultimedia ident="tbl0030"></elsevierMultimedia><elsevierMultimedia ident="tbl0035"></elsevierMultimedia><elsevierMultimedia ident="tbl0040"></elsevierMultimedia><elsevierMultimedia ident="tbl0045"></elsevierMultimedia><p id="par0135" class="elsevierStylePara elsevierViewall">El perfil de resistencias de los microorganismos implicados fue el siguiente&#58;</p><p id="par0140" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleUnderline">Estafilococos&#58;</span></p><p id="par0145" class="elsevierStylePara elsevierViewall">Se analiz&#243; por separado <span class="elsevierStyleItalic">S&#46; aureus</span> y SCN&#58;</p><p id="par0150" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Staphylococcus aureus&#58;</span></p><p id="par0155" class="elsevierStylePara elsevierViewall">De los 8 <span class="elsevierStyleItalic">S&#46; aureus</span> aislados causantes de bacteriemia en pacientes con infecci&#243;n abdominal&#44; 4 de ellos &#40;50&#37;&#41; fueron resistentes a oxacilina&#44; 4 &#40;50&#37;&#41; a levofloxacino&#44; 3 &#40;37&#44;5&#37;&#41; a tobramicina y 3 &#40;37&#44;5&#37;&#41; a clindamicina&#46; No se aisl&#243; ning&#250;n <span class="elsevierStyleItalic">S&#46; aureus</span> resistente a glucop&#233;ptidos&#44; rifampicina&#44; linezolid&#44; daptomicina o tigeciclina&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">Estafilococos coagulasa negativos&#58;</p><p id="par0165" class="elsevierStylePara elsevierViewall">De los 34 SCN aislados causantes de bacteriemia en pacientes con infecci&#243;n abdominal se detect&#243; que&#58; 26 &#40;76&#44;47&#37;&#41; fueron resistentes a oxacilina&#44; 26 &#40;76&#44;47&#37;&#41; a levofloxacino&#44; 19 &#40;55&#44;88&#37;&#41; a tobramicina&#44; 18 &#40;52&#44;94&#37;&#41; a gentamicina&#44; 19 &#40;55&#44;88&#37;&#41; a clindamicina&#44; 9 &#40;26&#44;47&#37;&#41; a rifampicina y 7 &#40;20&#44;58&#37;&#41; a linezolid&#46; No se aislaron SCN resistentes a glucop&#233;ptidos&#44; a daptomicina ni a tigeciclina&#46;</p><p id="par0170" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleUnderline">Estreptococos&#58;</span></p><p id="par0175" class="elsevierStylePara elsevierViewall">De los 13 estreptococos aislados&#44; tan solo se detectaron 4 resistentes a levofloxacino&#44; 4 a eritromicina y 2 a clindamicina&#46; No se aislaron estreptococos resistentes a penicilinas&#46;</p><p id="par0180" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleUnderline">Enterococos&#58;</span></p><p id="par0185" class="elsevierStylePara elsevierViewall">Se analiz&#243; por separado <span class="elsevierStyleItalic">E&#46; faecalis</span>&#44; <span class="elsevierStyleItalic">E&#46; faecium</span> y otros enterococos&#58;</p><p id="par0190" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Enterococcus faecalis&#58;</span></p><p id="par0195" class="elsevierStylePara elsevierViewall">De los 15 <span class="elsevierStyleItalic">E&#46; faecalis</span> aislados causantes de bacteriemia&#44; 9 &#40;60&#37;&#41; fueron resistentes a ciprofloxacino y 9 &#40;60&#37;&#41; a levofloxacino&#46; No se aislaron <span class="elsevierStyleItalic">E&#46; faecalis</span> resistentes a ampicilina&#44; glucop&#233;ptidos&#44; linezolid ni daptomicina&#46;</p><p id="par0200" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Enterococcus faecium&#58;</span></p><p id="par0205" class="elsevierStylePara elsevierViewall">De los 11 <span class="elsevierStyleItalic">E&#46; faecium</span> aislados causantes de bacteriemia&#44; 9 &#40;81&#44;81&#37;&#41; fueron resistentes a ampicilina&#44; 9 &#40;81&#44;81&#37;&#41; a levofloxacino&#44; 7 &#40;63&#44;63&#37;&#41; a ciprofloxacino y uno &#40;9&#44;09&#37;&#41; a vancomicina&#46; No se aislaron <span class="elsevierStyleItalic">E&#46; faecium</span> resistentes a linezolid ni daptomicina&#46;</p><p id="par0210" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleUnderline">Enterobacterias&#58;</span></p><p id="par0215" class="elsevierStylePara elsevierViewall">Se estudiaron por separado <span class="elsevierStyleItalic">E&#46; coli</span>&#44; <span class="elsevierStyleItalic">K&#46; pneumoniae</span>&#44; <span class="elsevierStyleItalic">P&#46; aeruginosa</span>&#44; <span class="elsevierStyleItalic">A&#46; baumanii</span> y otras enterobacterias&#46;</p><p id="par0220" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Escherichia coli&#58;</span></p><p id="par0225" class="elsevierStylePara elsevierViewall">De los 101 <span class="elsevierStyleItalic">E&#46; coli</span> aislados causantes de bacteriemia&#44; 25 &#40;24&#44;75&#37;&#41; fueron resistentes a amoxicilina-clavul&#225;nico&#44; 23 &#40;22&#44;77&#37;&#41; a cefuroxima&#44; 5 &#40;4&#44;95&#37;&#41; a cefoxitina&#44; 10 &#40;9&#44;90&#37;&#41; a cefotaxima&#44; 9 &#40;8&#44;91&#37;&#41; a ceftazidima&#44; 10 &#40;9&#44;90&#37;&#41; a cefepime&#44; 9 &#40;8&#44;91&#37;&#41; a piperacilina-tazobactam&#44; 36 &#40;35&#44;64&#37;&#41; a ciprofloxacino&#44; 26 &#40;25&#44;74&#37;&#41; a levofloxacino&#44; 10 &#40;9&#44;90&#37;&#41; a gentamicina&#44; 7 &#40;6&#44;93&#37;&#41; a tobramicina&#46; En total se detect&#243; que 10 &#40;9&#44;90&#37;&#41; <span class="elsevierStyleItalic">E&#46; coli</span> eran productoras de BLEE&#46; No se aisl&#243; ninguna <span class="elsevierStyleItalic">E&#46; coli</span> resistente a carbapenem&#46;</p><p id="par0230" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Klebsiella pneumoniae&#58;</span></p><p id="par0235" class="elsevierStylePara elsevierViewall">Del total de las 24 <span class="elsevierStyleItalic">K&#46; pneumoniae</span> aisladas&#44; se detectaron 2 &#40;8&#44;33&#37;&#41; resistentes a ciprofloxacino&#46; No se aisl&#243; ninguna <span class="elsevierStyleItalic">K&#46; pneumoniae</span> resistente a amoxicilina-clavul&#225;nico&#44; a cefalosporinas de 2&#46;<span class="elsevierStyleSup">a</span>&#44; 3&#46;<span class="elsevierStyleSup">a</span> ni 4&#46;<span class="elsevierStyleSup">a</span> generaci&#243;n&#44; a piperacilina-tazobactam&#44; carbapenem ni a aminogluc&#243;sidos&#46; No se aisl&#243;&#44; por lo tanto&#44; ninguna <span class="elsevierStyleItalic">K&#46; pneumoniae</span> BLEE&#46;</p><p id="par0240" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Pseudomonas aeruginosa&#58;</span></p><p id="par0245" class="elsevierStylePara elsevierViewall">Tan solo se aislaron 4 <span class="elsevierStyleItalic">P&#46; aeruginosa</span> causantes de bacteriemia&#46; Tres &#40;75&#37;&#41; fueron resistentes a ampicilina&#47;sulbactam&#44; una &#40;25&#37;&#41; a meropenem&#44; una &#40;25&#37;&#41; a imipenem&#44; una &#40;25&#37;&#41; a ciprofloxacino y una &#40;25&#37;&#41; a levofloxacino&#46; No se aisl&#243; ninguna <span class="elsevierStyleItalic">P&#46; aeruginosa</span> resistente a cefepime&#44; a piperacilina-tazobactam&#44; a aminogluc&#243;sidos&#44; a cotrimoxazol ni a colistina&#46;</p><p id="par0250" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Acinetobacter baumanii&#58;</span></p><p id="par0255" class="elsevierStylePara elsevierViewall">Del total de los 7 <span class="elsevierStyleItalic">A&#46; baumanii</span> aislados&#44; todos &#40;100&#37;&#41; fueron resistentes a ampicilina&#47;sulbactam&#44; a piperacilina&#47;tazobactam&#44; a cefepime&#44; a imipenem&#44; a meropenem&#44; a ciprofloxacino y a levofloxacino&#44; 6 &#40;85&#44;71&#37;&#41; fueron resistentes a gentamicina&#44; 2 &#40;28&#44;57&#37;&#41; a tobramicina y uno &#40;14&#44;28&#37;&#41; a rifampicina&#46; Ninguno &#40;0&#37;&#41; result&#243; resistente a amikacina&#44; a cotrimoxazol ni a colistina&#46;</p><p id="par0260" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Otras enterobacterias&#58;</span></p><p id="par0265" class="elsevierStylePara elsevierViewall">De todo el resto de enterobacterias&#44; tan solo destacar 7 resistentes a cefuroxima&#44; 7 &#40;24&#44;13&#37;&#41; a cefoxitina&#44; una &#40;3&#44;44&#37;&#41; a ceftazidima&#44; una &#40;3&#44;44&#37;&#41; a ciprofloxacino&#44; una &#40;3&#44;44&#37;&#41; a levofloxacino&#44; una &#40;3&#44;44&#37;&#41; a gentamicina&#44; una &#40;3&#44;44&#37;&#41; a tobramicina&#44; una &#40;3&#44;44 a amikacina y 2 &#40;6&#44;88&#37;&#41; &#40;un <span class="elsevierStyleItalic">Proteus mirabilis</span> y un <span class="elsevierStyleItalic">Proteus vulgaris</span>&#41; a imipenem&#46;</p><p id="par0270" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleUnderline">Hongos&#58;</span></p><p id="par0275" class="elsevierStylePara elsevierViewall">Se estudiaron por separado <span class="elsevierStyleItalic">C&#46; albicans</span> y <span class="elsevierStyleItalic">Candida</span> no albicans&#58;</p><p id="par0280" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Candida albicans&#58;</span></p><p id="par0285" class="elsevierStylePara elsevierViewall">De las 9 <span class="elsevierStyleItalic">C&#46; albicans</span> aisladas&#44; solamente una &#40;11&#44;11&#37;&#41; fue resistente a fluconazol&#46;</p><p id="par0290" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Candida</span> no albicans&#58;</p><p id="par0295" class="elsevierStylePara elsevierViewall">De todas las <span class="elsevierStyleItalic">Candida</span> no albicans aisladas&#44; tan solo detectamos una &#40;12&#44;5&#37;&#41; <span class="elsevierStyleItalic">Candida parapsilosis</span> resistente a caspofungina y anidulafungina y la &#250;nica <span class="elsevierStyleItalic">Candida krusei &#40;C&#46; krusei&#41;</span> aislada resistente a fluconazol&#46;</p><p id="par0300" class="elsevierStylePara elsevierViewall">Una vez que se estudian las resistencias de los microorganismos implicados&#44; consideramos que los microorganismos resistentes m&#225;s relevantes que hemos aislado&#44; y los que denominamos microorganismos resistentes&#44; son&#58; <span class="elsevierStyleItalic">S&#46; aureus</span> resistente a meticilina&#44; SCN resistentes a linezolid&#44; <span class="elsevierStyleItalic">E&#46; faecium</span> resistente a vancomicina&#44; <span class="elsevierStyleItalic">E&#46; coli</span> y <span class="elsevierStyleItalic">K&#46; pneumoniae</span> resistentes a cefalosporinas de 3&#46;<span class="elsevierStyleSup">a</span> generaci&#243;n o quinolonas&#44; <span class="elsevierStyleItalic">P&#46; aeruginosa</span> resistente a quinolonas o carbapenem&#46; <span class="elsevierStyleItalic">A&#46; baumanii</span> resistente quinolonas o carbapenem y <span class="elsevierStyleItalic">Candida</span> spp&#46; resistente a fluconazol y a equinocandinas&#46;</p><p id="par0305" class="elsevierStylePara elsevierViewall">El tipo de bacteriemia fue&#58; comunitaria un 49&#44;52&#37;&#44; asociada a cuidados sanitarios un 5&#44;66&#37; y nosocomial un 44&#44;81&#37;&#46;</p><p id="par0310" class="elsevierStylePara elsevierViewall">El uso previo de antibi&#243;tico fue positivo en un 50&#44;9&#37; y negativo en un 49&#44;1&#37;&#46;</p><p id="par0315" class="elsevierStylePara elsevierViewall">En este estudio se encontr&#243; una asociaci&#243;n estad&#237;sticamente significativa entre la administraci&#243;n de antibi&#243;tico previo y el aislamiento de microorganismos resistentes &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;013&#41; pero no con el lugar de adquisici&#243;n de la bacteriemia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;239&#41;&#46;</p><p id="par0320" class="elsevierStylePara elsevierViewall">La relaci&#243;n entre la administraci&#243;n de tratamiento antibi&#243;tico previo y el aislamiento de microorganismos resistentes&#44; utilizando la prueba chi cuadrado&#44; fue estad&#237;sticamente significativa &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;013&#41; y el riesgo relativo de aislamiento de microorganismos resistentes y administraci&#243;n de tratamiento antibi&#243;tico previo elevado &#40;1&#44;92&#41;&#46; El riesgo de aislamiento de microorganismos resistentes en los hemocultivos de los pacientes en los que se administr&#243; tratamiento antibi&#243;tico previo se muestra en la <a class="elsevierStyleCrossRef" href="#tbl0050">tabla 10</a>&#46; De los 212 pacientes con bacteriemia de origen abdominal&#44; en 108 pacientes &#40;50&#44;9&#37;&#41; se administr&#243; tratamiento antibi&#243;tico previo y de ellos&#44; en 32 pacientes &#40;29&#44;6&#37;&#41; se aislaron microorganismos resistentes&#46;</p><elsevierMultimedia ident="tbl0050"></elsevierMultimedia><p id="par0325" class="elsevierStylePara elsevierViewall">La relaci&#243;n entre el lugar de adquisici&#243;n de la bacteriemia y el aislamiento de microorganismos resistentes no result&#243; estad&#237;sticamente significativa &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;239&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0055">tabla 11</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0055"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Discusi&#243;n</span><p id="par0330" class="elsevierStylePara elsevierViewall">Este estudio muestra un an&#225;lisis reciente de los microorganismos implicados en la bacteriemia de origen abdominal y su perfil de resistencia en un hospital espa&#241;ol&#46;</p><p id="par0335" class="elsevierStylePara elsevierViewall">Los resultados de nuestro estudio muestran que los microorganismos implicados en bacteriemias en pacientes con infecci&#243;n abdominal son fundamentalmente enterobacterias gramnegativas&#44; especialmente <span class="elsevierStyleItalic">E&#46; coli</span> y <span class="elsevierStyleItalic">K&#46; pneumoniae</span>&#44; aunque tambi&#233;n hay una presencia nada despreciable de grampositivos&#44; especialmente SCN y enterococos&#46; De los hongos&#44; resulta sorprendente que sean m&#225;s frecuentes las <span class="elsevierStyleItalic">Candida</span> no albicans &#40;un 64&#37; de las fungemias&#41;&#46;</p><p id="par0340" class="elsevierStylePara elsevierViewall">Afortunadamente&#44; los microorganismos m&#225;s frecuentes&#44; <span class="elsevierStyleItalic">E&#46; coli</span> y <span class="elsevierStyleItalic">K&#46; pneumoniae</span>&#44; todav&#237;a presentan un perfil terap&#233;utico amplio&#46; La incidencia de <span class="elsevierStyleItalic">E&#46; coli</span> BLEE es de un 9&#44;90&#37; y no aislamos ninguna <span class="elsevierStyleItalic">K&#46; pneumoniae</span> BLEE&#44; sin embargo las resistencias a fluorquinolonas s&#237; son destacables &#40;un 35&#44;64&#37; de las <span class="elsevierStyleItalic">E&#46; coli</span> y un 8&#44;33&#37; de las <span class="elsevierStyleItalic">K&#46; pneumoniae</span> aisladas&#41;&#46; No se detectaron <span class="elsevierStyleItalic">E&#46; coli</span> ni <span class="elsevierStyleItalic">K&#46; pneumoniae</span> resistentes a carbapenem&#46; Las escasas <span class="elsevierStyleItalic">P&#46; aeruginosa</span> aisladas tambi&#233;n presentan un perfil de resistencias en global bajo comparado con otros estudios<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">17</span></a>&#46; Resulta realmente preocupante el perfil de resistencias de los <span class="elsevierStyleItalic">A&#46; baumanii</span> aislados&#44; con un perfil terap&#233;utico muy limitado&#59; amikacina&#44; cotrimoxazol y colistina fueron los &#250;nicos antimicrobianos testados para los que no presentaron resistencias&#46;</p><p id="par0345" class="elsevierStylePara elsevierViewall">Con respecto a los grampositivos&#44; la incidencia de <span class="elsevierStyleItalic">S&#46; aureus</span> es baja pero dentro de estos&#44; la incidencia de <span class="elsevierStyleItalic">S&#46; aureus</span> resistentes a meticilina es alta &#40;50&#37;&#41;&#46; No aislamos <span class="elsevierStyleItalic">S&#46; aureus</span> resistentes a rifampicina&#46; Los estafilococos no aureus presentaron una resistencia muy elevada a muchos grupos de antimicrobianos y resulta alarmante que ya comiencen a aparecer resistencias a linezolid&#46; De los enterococos&#44; aislamos un <span class="elsevierStyleItalic">E&#46; faecium</span> resistente a vancomicina&#44; que para nuestra muestra supone una elevada incidencia &#40;3&#44;12&#37;&#41;&#46;</p><p id="par0350" class="elsevierStylePara elsevierViewall">En el estudio&#44; resulta muy llamativo que solamente hallamos una <span class="elsevierStyleItalic">Candida</span> no albicans <span class="elsevierStyleItalic">&#40;C&#46; krusei&#41;</span> resistente a fluconazol&#46;</p><p id="par0355" class="elsevierStylePara elsevierViewall">La alta incidencia de los bacilos gramnegativos&#44; principalmente <span class="elsevierStyleItalic">E&#46; coli</span> y <span class="elsevierStyleItalic">K&#46; pneumoniae</span> en nuestro estudio&#44; se debe al origen abdominal de la bacteriemia&#46; Otros estudios de microorganismos implicados en bacteriemias como el EUROBACT<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">18</span></a> muestran mayor prevalencia de otros microorganismos&#44; como <span class="elsevierStyleItalic">Acinetobacter</span> spp&#46; y <span class="elsevierStyleItalic">Pseudomonas</span> spp&#46;&#44; ya que estudian los microorganismos implicados en bacteriemias de diversos or&#237;genes y no exclusivamente de origen abdominal&#46; En el Estudio Nacional de Vigilancia de Infecci&#243;n Nosocomial &#40;ENVIN&#41;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">17</span></a>&#44; en el apartado de bacteriemias secundarias a otros focos&#44; la distribuci&#243;n de microorganismos aislados es semejante a los resultados de nuestro estudio&#44; aunque en este estudio de 151 hospitales espa&#241;oles tambi&#233;n existe una mayor incidencia de <span class="elsevierStyleItalic">A&#46; baumanii y P&#46; aeruginosa</span> que en nuestro hospital&#46;</p><p id="par0360" class="elsevierStylePara elsevierViewall">Otros estudios actuales sobre microorganismos aislados y resistencias bacterianas tambi&#233;n se han realizado con datos de microorganismos implicados en infecciones en general&#44; y no exclusivamente en microorganismos causantes de bacteriemias&#44; como los estudios&#58; Estudio de Prevalencia de las Infecciones Nosocomiales en Espa&#241;a &#40;EPINE-EPPS 2013&#41;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">19</span></a> y European Antimicrobial Resistance Surveillance network &#40;EARS-net&#41;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">20</span></a>&#46;</p><p id="par0365" class="elsevierStylePara elsevierViewall">Si comparamos nuestros resultados de perfil de resistencias con el estudio ENVIN<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">17</span></a>&#44; en el apartado de bacteriemias secundarias a otros focos&#44; observamos que en nuestro estudio hay una incidencia de <span class="elsevierStyleItalic">S&#46; aureus</span> resistentes a meticilina semejante&#44; y en general&#44; menor perfil de resistencia del resto de microorganismos multirresistentes&#46;</p><p id="par0370" class="elsevierStylePara elsevierViewall">En el &#250;ltimo an&#225;lisis de resistencia antimicrobiana de la OMS titulado &#171;<span class="elsevierStyleItalic">Antimicrobial resistance&#58; global report on surveillance</span> &#40;Resistencia a los antimicrobianos&#58; informe mundial sobre la vigilancia&#41;&#187; destaca la importancia de <span class="elsevierStyleItalic">E&#46; coli</span> resistente a cefalosporinas de 3&#46;<span class="elsevierStyleSup">a</span> generaci&#243;n y fluorquinolonas&#44; <span class="elsevierStyleItalic">K&#46; pneumoniae</span> resistentes a cefalosporinas de 3&#46;<span class="elsevierStyleSup">a</span> generaci&#243;n y carbapenem y <span class="elsevierStyleItalic">S&#46; aureus</span> resistentes a meticilina como microorganismos resistentes responsables de bacteriemia y su implicaci&#243;n en la mala evoluci&#243;n de los pacientes<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">8</span></a>&#46;</p><p id="par0375" class="elsevierStylePara elsevierViewall">Muchos estudios han demostrado que la exposici&#243;n previa a antibi&#243;ticos y el lugar de origen de la infecci&#243;n son factores de riesgo asociados a la presencia de microorganismos resistentes<a class="elsevierStyleCrossRefs" href="#bib0230"><span class="elsevierStyleSup">21&#8211;25</span></a>&#46; En nuestro estudio la exposici&#243;n previa a antibi&#243;ticos s&#237; se relacion&#243; de forma estad&#237;sticamente significativa con la presencia de microorganismos resistentes&#44; pero no el lugar de adquisici&#243;n de la bacteriemia&#46; Estos resultados confirman la necesidad de preguntar espec&#237;ficamente por la administraci&#243;n de antibi&#243;ticos durante los 3 meses previos a la bacteriemia en la anamnesis de los pacientes con bacteriemia de origen abdominal&#46;</p><p id="par0380" class="elsevierStylePara elsevierViewall">Las principales limitaciones de nuestro estudio son que se ha realizado en un solo centro y sobre un tipo de pacientes determinado&#44; por lo que no se puede extrapolar a todo el &#225;mbito nacional ni a todas las bacteriemias&#46; Los resultados de prevalencia de microorganismos implicados y de resistencia antibi&#243;tica han de ser interpretados en cada centro y con precauci&#243;n&#46;</p><p id="par0385" class="elsevierStylePara elsevierViewall">Todos los pacientes seleccionados presentan bacteriemia de origen abdominal&#44; por tanto&#44; la poblaci&#243;n de nuestro estudio es muy homog&#233;nea&#46; Estos resultados pueden ser muy &#250;tiles para actualizar los protocolos terap&#233;uticos emp&#237;ricos en esta selecci&#243;n de pacientes&#46;</p><p id="par0390" class="elsevierStylePara elsevierViewall">Resulta necesario realizar estudios de resistencia actuales peri&#243;dicamente en cada centro hospitalario y para cada grupo de pacientes&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conclusiones</span><p id="par0395" class="elsevierStylePara elsevierViewall">Los resultados de este estudio muestran que las bacterias causantes de bacteriemia en pacientes con infecci&#243;n abdominal son principalmente enterobacterias&#44; sobre todo <span class="elsevierStyleItalic">E&#46; coli</span> y <span class="elsevierStyleItalic">K&#46; pneumoniae</span> seguido de bacterias grampositivas&#44; SCN y enterococos&#46; En cuanto al perfil de resistencias&#44; se realiza un estudio descriptivo de los principales microorganismos implicados para los distintos grupos antimicrobianos&#46; Se demuestra la asociaci&#243;n entre uso de antibi&#243;tico previo y presencia de microorganismos resistentes&#46;</p><p id="par0400" class="elsevierStylePara elsevierViewall">En base a estos resultados&#44; est&#225; m&#225;s que justificado&#44; en los pacientes con bacteriemia de origen abdominal&#44; iniciar un tratamiento emp&#237;rico de amplio espectro para cobertura polimicrobiana&#44; cubriendo las diferentes posibilidades de g&#233;rmenes resistentes tanto para grampositivos como para gramnegativos&#44; sobre todo si el paciente ha estado expuesto a tratamiento antibi&#243;tico previo&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Responsabilidades &#233;ticas</span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Protecci&#243;n de personas y animales</span><p id="par0405" class="elsevierStylePara elsevierViewall">Los autores declaran que para esta investigaci&#243;n no se han realizado experimentos en seres humanos ni en animales&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Confidencialidad de los datos</span><p id="par0410" class="elsevierStylePara elsevierViewall">Los autores declaran que han seguido los protocolos de su centro de trabajo sobre la publicaci&#243;n de datos de pacientes&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Derecho a la privacidad y consentimiento informado</span><p id="par0415" class="elsevierStylePara elsevierViewall">Los autores declaran que en este art&#237;culo no aparecen datos de pacientes&#46;</p></span></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Financiaci&#243;n</span><p id="par0420" class="elsevierStylePara elsevierViewall">Este trabajo no ha sido financiado total ni parcialmente por ninguna entidad t&#233;cnica ni econ&#243;mica&#44; y no ha recibido ning&#250;n tipo de ayuda ni beca&#46;</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Conflicto de intereses</span><p id="par0425" class="elsevierStylePara elsevierViewall">No existe conflicto de intereses&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La presencia de microorganismos resistentes es una causa importante de fallo en el tratamiento antimicrobiano inicial&#46; Los objetivos de este estudio son conocer el perfil de resistencia de los microorganismos causantes de bacteriemia de origen abdominal e identificar si el uso previo de antibi&#243;ticos y el lugar de adquisici&#243;n de la bacteriemia son factores de riesgo para determinar la presencia de microorganismos resistentes&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material y m&#233;todo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se dise&#241;&#243; un estudio de cohorte retrospectiva de todos los pacientes adultos que presentaron bacteriemia y&#47;o fungemia cuyo foco infeccioso primario fue de origen abdominal ingresados en un hospital universitario durante los a&#241;os 2011-2013&#46; Se describieron los perfiles de resistencia a los antimicrobianos y se utiliz&#243; una comparaci&#243;n de proporciones con un test chi cuadrado al 95&#37; de confianza para determinar si las variables estudiadas fueron factores de riesgo en el aislamiento de microorganismos resistentes&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">De un total de 1&#46;245 pacientes con bacteriemia&#44; 212 &#40;17&#37;&#41; presentaron bacteriemia de origen abdominal&#46; Respecto al perfil de resistencias destac&#243; <span class="elsevierStyleItalic">Staphylococcus aureus</span> resistente a meticilina &#40;50&#37;&#41;&#44; estafilococos coagulasa negativos resistentes a linezolid &#40;20&#44;58&#37;&#41;&#44; enterococos resistentes a vancomicina &#40;3&#44;12&#37;&#41;&#44; <span class="elsevierStyleItalic">Escherichia coli</span> resistente a cefalosporinas de 3&#46;<span class="elsevierStyleSup">a</span> generaci&#243;n &#40;9&#44;9&#37;&#41; y fluorquinolonas &#40;35&#44;64&#37;&#41;&#44; <span class="elsevierStyleItalic">Klebsiella pneumoniae</span> resistente a fluorquinolonas &#40;8&#44;33&#37;&#41;&#44; <span class="elsevierStyleItalic">Pseudomonas aeruginosa</span> resistente a quinolonas y carbapenem &#40;25 y 25&#37; respectivamente&#41;&#44; <span class="elsevierStyleItalic">Acinetobacter baumanii</span> resistente a quinolonas y carbapenem &#40;100&#37; y 100&#37; respectivamente&#41;&#44; <span class="elsevierStyleItalic">Candida albicans</span> resistente a fluconazol &#40;11&#44;11&#37;&#41;&#44; la &#250;nica <span class="elsevierStyleItalic">Candida krusei</span> aislada resistente a fluconazol y <span class="elsevierStyleItalic">Candida parapsilosis</span> resistente a equinocandinas &#40;12&#44;5&#37;&#41;&#46; En nuestro estudio&#44; el uso previo de antibi&#243;tico tuvo asociaci&#243;n estad&#237;sticamente significativa con el aislamiento de microorganismos resistentes &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;013&#41; pero no el lugar de adquisici&#243;n de la bacteriemia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;239&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Conocer la incidencia de microorganismos resistentes en cada hospital puede mejorar el tratamiento antimicrobiano emp&#237;rico inicial en pacientes con bacteriemia de origen abdominal&#46; El uso previo de antibi&#243;ticos se relacion&#243; de forma estad&#237;sticamente significativa con el aislamiento de microorganismos resistentes&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objetivo"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Material y m&#233;todo"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusiones"
          ]
        ]
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      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The presence of resistant microorganisms is a major cause of failure in initial empirical antimicrobial therapy&#46; The objectives of this study are to determine the resistance profile of microorganisms that cause bacteraemia of abdominal origin and to identify whether the previous use of antibiotics and the place of acquisition of bacteraemia are risk factors associated with the presence of resistant organisms&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A clinical&#44; observational&#44; epidemiological&#44; retrospective cohort study was conducted with all the adult patients admitted to a university hospital from 2011-2013&#46; Antimicrobial resistance profiles were described and a 95&#37; confidence interval chi-square test was used to determine whether the variables studied were risk factors in the isolation of resistant microorganisms&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Of the 1245 patients with bacteraemia&#44; 212 &#40;17&#37;&#41; presented bacteraemia of abdominal origin&#46; The resistance profile highlights the incidence of methicillin resistant <span class="elsevierStyleItalic">Staphylococcus aureus</span> &#40;50&#37;&#41;&#44; coagulase-negative staphylococci resistant to linezolid &#40;20&#46;58&#37;&#41;&#44; enterococci resistant to vancomycin &#40;3&#46;12&#37;&#41;&#44; <span class="elsevierStyleItalic">Escherichia coli</span> resistant to third-generation cephalosporins &#40;9&#46;9&#37;&#41; and fluoroquinolones &#40;35&#46;64&#37;&#41;&#44; <span class="elsevierStyleItalic">Klebsiella pneumoniae</span> resistant to third-generation cephalosporins &#40;8&#46;33&#37;&#41;&#44; <span class="elsevierStyleItalic">Pseudomonas aeruginosa</span> resistant to fluoroquinolones and carbapenem &#40;25&#37; and 25&#37; respectively&#41; and <span class="elsevierStyleItalic">Acinetobacter baumanii</span> resistant to fluoroquinolones and carbapenem &#40;100&#37; and 100&#37; respectively&#41;&#44; <span class="elsevierStyleItalic">Candida albicans</span> resistant to fluconazole &#40;11&#46;11&#37;&#41;&#44; single <span class="elsevierStyleItalic">Candida krusei</span> isolate resistant to fluconazole and <span class="elsevierStyleItalic">Candida parapsilosis</span> resistant to echinocandins &#40;12&#46;5&#37;&#41;&#46; In our study&#44; previous use of antibiotics had a statistically significant association with the isolation of resistant microorganisms &#40;<span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;013&#41; but not the place of acquisition of bacteraemia &#40;<span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;239&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusion</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Establishing the incidence of resistant organisms can improve empirical antimicrobial therapy in patients with bacteraemia of abdominal origin&#46; Previous use of antibiotics was statistically significantly related to the isolation of resistant microorganisms&#46;</p></span>"
        "secciones" => array:4 [
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            "identificador" => "abst0025"
            "titulo" => "Objective"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Material and methods"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Results"
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          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusion"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Este trabajo ha sido aprobado por el Comit&#233; &#201;tico del Hospital Dr&#46; Peset de Valencia&#44; donde se ha realizado &#40;C&#243;digo CEIC 33&#47;14&#41;&#44; de acuerdo con la Declaraci&#243;n de Helsinki y la Asociaci&#243;n M&#233;dica Mundial&#44; y garantiza el derecho de los pacientes a la privacidad y confidencialidad&#46;</p>"
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          "leyenda" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">DE&#58; desviaci&#243;n est&#225;ndar&#59; IC 95&#37;&#58; intervalo de confianza al 95&#37;&#46;</p>"
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sexo &#40;frecuencia&#41; &#40;IC 95&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Edad en a&#241;os media<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>DE &#40;IC 95&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Hombres 126 &#40;59&#44;4&#37;&#41; &#40;52&#44;94-66&#44;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70&#44;62<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>14&#44;17 &#40;68&#44;70-72&#44;53&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Mujeres 86 &#40;40&#44;6&#37;&#41; &#40;33&#44;89-47&#44;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">73&#44;65<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>16&#44;88 &#40;71&#44;36-75&#44;93&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">212&nbsp;\t\t\t\t\t\t\n
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          "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Caracter&#237;sticas demogr&#225;ficas de los pacientes con bacteriemia y&#47;o fungemia de origen abdominal</p>"
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          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">CPRE&#58; colangiopancreatograf&#237;a retr&#243;grada endosc&#243;pica&#59; IC 95&#37;&#58; intervalo de confianza al 95&#37;&#46;</p>"
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                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Diagn&#243;sticos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">N&#250;mero &#40;porcentaje&#41; &#40;IC 95&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Colangitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">63 &#40;29&#44;71&#41; &#40;23&#44;65-36&#44;35&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Colecistitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">32 &#40;15&#44;09&#41; &#40;10&#44;55-20&#44;63&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pancreatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19 &#40;8&#44;96&#41; &#40;5&#44;48-13&#44;64&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Dehiscencia de sutura quir&#250;rgica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16 &#40;7&#44;54&#41; &#40;4&#44;37-11&#44;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Abdominal desconocido&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15 &#40;7&#44;07&#41; &#40;4&#44;01-11&#44;40&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Oclusi&#243;n intestinal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14 &#40;6&#44;6&#41; &#40;3&#44;65-10&#44;83&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Gastroenteritis&#47;enterocolitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8 &#40;3&#44;77&#41; &#40;1&#44;64-7&#44;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Perforaci&#243;n v&#237;scera hueca abdominal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8 &#40;3&#44;77&#41; &#40;1&#44;64-7&#44;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Postoperatorio resecci&#243;n intestinal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8 &#40;3&#44;77&#41; &#40;1&#44;64-7&#44;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Absceso intraabdominal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 &#40;2&#44;83&#41; &#40;1&#44;04-6&#44;05&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Absceso intravisceral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5 &#40;2&#44;35&#41; &#40;0&#44;77-5&#44;41&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Diverticulitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;1&#44;41&#41; &#40;0&#44;29-4&#44;08&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Colitis isqu&#233;mica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;1&#44;41&#41; &#40;0&#44;29-4&#44;08&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Postoperatorio colecistectom&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;1&#44;41&#41; &#40;0&#44;29-4&#44;08&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Postoperatorio hepatectom&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2 &#40;0&#44;94&#41; &#40;0&#44;11-3&#44;36&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Post-CPRE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2 &#40;0&#44;94&#41; &#40;0&#44;11-3&#44;36&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Apendicitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;0&#44;47&#41; &#40;0&#44;01-2&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Enfermedad inflamatoria intestinal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;0&#44;47&#41; &#40;0&#44;01-2&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Postoperatorio esofaguectom&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;0&#44;47&#41; &#40;0&#44;01-2&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Postoperatorio gastrectom&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;0&#44;47&#41; &#40;0&#44;01-2&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Postoperatorio embolizaci&#243;n hep&#225;tica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;0&#44;47&#41; &#40;0&#44;01-2&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Diagn&#243;sticos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">N&#250;mero &#40;&#37;&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20 &#40;9&#44;43&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Insuficiencia cardiaca&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;8&#44;96&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Diabetes mellitus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">53 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Insuficiencia renal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81 &#40;38&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Enfermedad oncol&#243;gica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">61 &#40;28&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tratamiento inmunosupresor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;1&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Leucopenia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;4&#44;24&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tratamiento con corticoides&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;3&#44;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tratamiento con quimioterapia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;7&#44;54&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">168 &#40;79&#44;24&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Klebsiella pneumoniae</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24 &#40;11&#44;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Klebsiella oxytoca</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;3&#44;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Enterobacter cloacae</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;2&#44;83&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Enterobacter aerogenes</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;0&#44;94&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Pseudomonas aeruginosa</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;1&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Pseudomonas</span> spp&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;0&#44;94&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Acinetobacter baumanii</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;3&#44;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Proteus</span> spp&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;1&#44;41&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Aeromona hydrophila</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;1&#44;41&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Stenotrophomona maltophila</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;0&#44;47&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Otras enterobacterias&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;3&#44;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Grampositivos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">87 &#40;41&#44;03&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Staphylococcus aureus</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#40;3&#44;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Staphylococcus epidermidis</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20 &#40;9&#44;43&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="left" valign="middle"><span class="elsevierStyleHsp" style=""></span>SCN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;6&#44;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Enterocuccus faecalis</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;7&#44;07&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Enterococcus faecium</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;5&#44;18&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Enterococcus</span> spp&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;2&#44;83&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Streptococcus pneumoniae</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;1&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Streptococcus bovis</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;1&#44;41&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Streptococcus</span> grupo <span class="elsevierStyleItalic">viridans</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;2&#44;83&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Anaerobios</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;2&#44;83&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Clostridium perfringens</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;1&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Peptoestreptococcus anaerobius</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;0&#44;94&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hongos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25 &#40;11&#44;79&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Candida albicans</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;4&#44;24&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">Candida</span> no albicans&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;7&#44;54&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">S&#46; aureus</span> &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>8&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">SCN &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>34&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Antibi&#243;tico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Oxacilina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">76&#44;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Gentamicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#44;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tobramicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">37&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">55&#44;88&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Levofloxacino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">76&#44;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Vancomicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Teicomicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Eritromicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Clindamicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">37&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">55&#44;88&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Linezolid&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#44;58&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Daptomicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tigeciclina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Rifampicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#44;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1534595.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Staphylococcus aureus y</span> estafilococos coagulasa negativos causantes de bacteriemia de origen abdominal</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0030"
        "etiqueta" => "Tabla 6"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at6"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">N&#58; n&#250;mero&#59; R&#58; resistente&#59; &#37; R&#58; &#37; resistencia&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">Enterococcus faecalis</span> &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>15&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">Enterococcus faecium</span> &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>11&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Antibi&#243;tico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ampicilina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81&#44;81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ciprofloxacino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63&#44;63&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Levofloxacino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81&#44;81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Vancomicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;09&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Teicoplanina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Linezolid&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Daptomicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
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                0 => "xTab1534604.png"
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          "es" => "<p id="spar0095" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Enterococcus faecalis y Enterococcus faecium</span> causantes de bacteriemia de origen abdominal</p>"
        ]
      ]
      6 => array:8 [
        "identificador" => "tbl0035"
        "etiqueta" => "Tabla 7"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at7"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0110" class="elsevierStyleSimplePara elsevierViewall">N&#58; n&#250;mero&#59; R&#58; resistente&#59; &#37; R&#58; &#37; resistencia&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">E&#46; coli</span> &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>101&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">K&#46; pneumoniae &#40;</span>N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>24&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Antibi&#243;tico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Amoxicilina-clavul&#225;nico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24&#44;75&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cefuroxima&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#44;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cefoxitima&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cefotaxima&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ceftazidima&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;91&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cefepime&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Piperacilina-tazobactam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;91&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Meropenem&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Imipenem&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ciprofloxacino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35&#44;64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;33&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Levofloxacino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#44;74&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Gentamicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tobramicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;93&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Amikacina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1534602.png"
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        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0105" class="elsevierStyleSimplePara elsevierViewall">Principales enterobacterias causantes de bacteriemia de origen abdominal</p>"
        ]
      ]
      7 => array:8 [
        "identificador" => "tbl0040"
        "etiqueta" => "Tabla 8"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
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        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at8"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0120" class="elsevierStyleSimplePara elsevierViewall">N&#58; n&#250;mero&#59; NT&#58; no testado&#59; R&#58; resistente&#59; &#37; R&#58; &#37; resistencia&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">P&#46; aeruginosa</span> &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>4&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">A&#46; baumanii</span> &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>7&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Antibi&#243;tico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ampicilina-sulbactam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">75&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cefepime&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Piperacilina-tazobactam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Meropenem&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Imipenem&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ciprofloxacino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Levofloxacino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Gentamicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">85&#44;71&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tobramicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28&#44;57&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Amikacina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Rifampicina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cotrimoxazol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Colistina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1534600.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0115" class="elsevierStyleSimplePara elsevierViewall">Bacilos gramnegativos no fermentadores causantes de bacteriemia de origen abdominal</p>"
        ]
      ]
      8 => array:8 [
        "identificador" => "tbl0045"
        "etiqueta" => "Tabla 9"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at9"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0130" class="elsevierStyleSimplePara elsevierViewall">N&#58; n&#250;mero&#59; NT&#58; no testado&#59; R&#58; resistente&#59; &#37; R&#58; &#37; resistencia&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">Candida albicans</span><br>&#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>9&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">Candida parapsilosis</span> &#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>8&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">Candida glabrata</span><br>&#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>4&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">Candida tropicalis</span><br>&#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#41;</th><th class="td" title="table-head  " colspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">Candida krusei</span><br>&#40;N<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Antif&#250;ngico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37; R&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Anfotericina B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Fluconazol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">100&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Voriconazol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Itraconazol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Posaconazol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Micafungina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Caspofungina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Anidulafungina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">5-fluorocitosina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1534596.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0125" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Candida albicans</span> y <span class="elsevierStyleItalic">Candida</span> no albicans causantes de fungemia de origen abdominal</p>"
        ]
      ]
      9 => array:8 [
        "identificador" => "tbl0050"
        "etiqueta" => "Tabla 10"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at10"
            "detalle" => "Tabla 1"
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0140" class="elsevierStyleSimplePara elsevierViewall">N&#58; n&#250;mero&#59; RR&#58; riesgo relativo&#46;</p><p id="spar0145" class="elsevierStyleSimplePara elsevierViewall">RR<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#44;92&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Microorganismos resistentes</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Antibi&#243;tico previo</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">76 &#40;35&#44;8&#41;<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">108 &#40;50&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">88 &#40;84&#44;6&#41;<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">104 &#40;49&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">164 &#40;77&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">212 &#40;100&#41;&nbsp;\t\t\t\t\t\t\n
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          "leyenda" => "<p id="spar0155" class="elsevierStyleSimplePara elsevierViewall">N&#58; n&#250;mero&#46;</p><p id="spar0160" class="elsevierStyleSimplePara elsevierViewall">p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;239&#46;</p>"
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                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
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        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:25 [
            0 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Blood stream infections of abdominal origin in the intensive care unit&#58; Characteristics and determinants of death"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;J&#46; De Waele"
                            1 => "E&#46;A&#46; Hoste"
                            2 => "S&#46;I&#46; Blot"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Surg Infect &#40;Larchmt&#41;"
                        "fecha" => "2008"
                        "volumen" => "9"
                        "paginaInicial" => "171"
                        "paginaFinal" => "177"
                      ]
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            1 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inadequate source control and inappropiate antibiotics are key determinants of mortality in patients with intra-abdominal sepsis and associated bacteremia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "B&#46; Tellor"
                            1 => "L&#46;P&#46; Skrupky"
                            2 => "W&#46; Symons"
                            3 => "E&#46; High"
                            4 => "S&#46;T&#46; Micek"
                            5 => "J&#46;E&#46; Mazuski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Surg Infect &#40;Larchmt&#41;"
                        "fecha" => "2015"
                        "volumen" => "16"
                        "paginaInicial" => "785"
                        "paginaFinal" => "793"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical predictors for enterococcal bacteraemia in patients with bacteraemic intra-abdominal infections"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "Korean Network for the Study of Infectious Diseases"
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46;I&#46; Kang"
                            1 => "D&#46;R&#46; Chung"
                            2 => "K&#46;S&#46; Ko"
                            3 => "K&#46;R&#46; Peck"
                            4 => "J&#46;-H&#46; Song"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3109/00365548.2010.492784"
                      "Revista" => array:6 [
                        "tituloSerie" => "Scand J Infect Dis&#46;"
                        "fecha" => "2010"
                        "volumen" => "42"
                        "paginaInicial" => "817"
                        "paginaFinal" => "820"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20560869"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in critically ill patients&#58; Clinical outcome and length of hospitalization"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46; Blot"
                            1 => "K&#46; Vandewoude"
                            2 => "D&#46; de Bacquer"
                            3 => "F&#46; Colardyn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/340616"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Infect Dis"
                        "fecha" => "2002"
                        "volumen" => "34"
                        "paginaInicial" => "1600"
                        "paginaFinal" => "1606"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12032895"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
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              "identificador" => "bib0150"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nosocomial bacteremia in a medical-surgical intensive care unit&#58; Epidemiologic characteristics and factors influencing mortality in 111 episodes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Rello"
                            1 => "M&#46; Ricart"
                            2 => "B&#46; Mirelis"
                            3 => "E&#46; Quintana"
                            4 => "M&#46; Gurgui"
                            5 => "A&#46; Net"
                          ]
                        ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med"
                        "fecha" => "1994"
                        "volumen" => "20"
                        "paginaInicial" => "94"
                        "paginaFinal" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8201105"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0155"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Excess risk of death from intensive care unit-acquired nosocomial bloodstream infections&#58; A reappraisal"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "and OUTCOMEREA Study Group"
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Garrouste-Orgeas"
                            1 => "J&#46;F&#46; Timsit"
                            2 => "M&#46; Tafflet"
                            3 => "B&#46; Misset"
                            4 => "J&#46;R&#46; Zahar"
                            5 => "L&#46; Soufir"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/500318"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Infect Dis&#46;"
                        "fecha" => "2006"
                        "volumen" => "42"
                        "paginaInicial" => "1118"
                        "paginaFinal" => "1126"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16575729"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units&#58; A cohort study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;L&#46; Lambert"
                            1 => "C&#46; Suetens"
                            2 => "A&#46; Savey"
                            3 => "M&#46; Palomar"
                            4 => "M&#46; Hiesmayr"
                            5 => "I&#46; Morales"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S1473-3099(10)70258-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet Infect Dis&#46;"
                        "fecha" => "2011"
                        "volumen" => "11"
                        "paginaInicial" => "30"
                        "paginaFinal" => "38"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21126917"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "World Health Organization&#46; Antimicrobial resistance&#58; global report on surveillance&#46; 2014 &#91;consultado Feb 2016&#93;&#46; Disponible en&#58;<a href="http://www.who.int/drugresistance/documents/surveillancereport/en">http&#58;&#47;&#47;www&#46;who&#46;int&#47;drugresistance&#47;documents&#47;surveillancereport&#47;en</a>"
                ]
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            ]
            8 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Analysis of 4758 Escherichia coli bacteraemia episodes&#58; predictive factors for isolation of an antibiotic-resistant strain and their impact on the outcome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Ortega M1"
                            1 => "F&#46; Marco"
                            2 => "A&#46; Soriano"
                            3 => "M&#46; Almela"
                            4 => "J&#46;A&#46; Mart&#237;nez"
                            5 => "A&#46; Mu&#241;oz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/jac/dkn514"
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Antimicrob Chemother&#46;"
                        "fecha" => "2009"
                        "volumen" => "63"
                        "paginaInicial" => "568"
                        "paginaFinal" => "574"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19126669"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0175"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A multinational survey of risk factors for infection with extended-spectrum b-lactamase-producing enterobacteriaceae in nonhospitalized patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Ben-Ami"
                            1 => "J&#46; Rodr&#237;guez-Ba&#241;o"
                            2 => "H&#46; Arslan"
                            3 => "J&#46; Pitout"
                            4 => "C&#46; Quentin"
                            5 => "E&#46; Calbo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/604713"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Infect Dis"
                        "fecha" => "2009"
                        "volumen" => "49"
                        "paginaInicial" => "682"
                        "paginaFinal" => "690"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19622043"
                            "web" => "Medline"
                          ]
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                      ]
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                  ]
                ]
              ]
            ]
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              "identificador" => "bib0180"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Gu&#237;a para el diagn&#243;stico y tratamiento del paciente con bacteriemia Gu&#237;as de la Sociedad Espa&#241;ola de Enfermedades Infecciosas y Microbiolog&#237;a Cl&#237;nica &#40;SEIMC&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;M&#46; Cisneros-Herreros"
                            1 => "J&#46; Cobo-Reinoso"
                            2 => "M&#46; Pujol-Rojo"
                            3 => "J&#46; Rodr&#237;guez-Ba&#241;o"
                            4 => "M&#46; Salavert-Llet&#237;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Enferm Infecc Microbiol Clin"
                        "fecha" => "2007"
                        "volumen" => "25"
                        "paginaInicial" => "111"
                        "paginaFinal" => "130"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17288909"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Cercenado E&#44; Cant&#243;n R&#44; editores&#46; Procedimientos en Microbiolog&#237;a Cl&#237;nica&#46; Recomendaciones de la Sociedad Espa&#241;ola de Enfermedades Infecciosas y Microbiolog&#237;a Cl&#237;nica&#46; Hemocultivos&#46; 2003 &#91;consultado Feb 2013&#93;&#46;Disponible en&#58; <a href="https://www.seimc.org/contenidos/documentoscientificos/procedimientosmicrobiologia/seimc-procedimientomicrobiologia3a.pdf">https&#58;&#47;&#47;www&#46;seimc&#46;org&#47;contenidos&#47;documentoscientificos&#47;procedimientosmicrobiologia&#47;seimc-procedimientomicrobiologia3a&#46;pdf</a>"
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reference method for broth dilution antifungal susceptibility testing of yeast&#59; approved standard CLSI document M27- A3"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Clinical LaboratoryStandards Institute &#40;CLSI&#41;"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "edicion" => "Third ed"
                        "fecha" => "2008"
                        "editorial" => "Clinical Laboratory Standards Institute"
                        "editorialLocalizacion" => "Wayne&#44; Pennsylvania&#44; USA"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Performance standards for antimicrobial susceptibility testing&#59; eighteenth informational supplement&#46; CLSI document M100-S19"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Clinical Laboratory Standards Institute &#40;CLSI&#41;"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2009"
                        "editorial" => "Clinical Laboratory Standards Institute"
                        "editorialLocalizacion" => "Wayne&#44; Pennsylvania&#44; USA"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Calvo J&#44; Cant&#243;n R&#44; Fern&#225;ndez Cuenca F&#44; Mirelis B&#44; Navarro F&#46; Detecci&#243;n fenot&#237;pica de mecanismos de resistencia en gramnegativos&#46; En&#58; Cercenado E&#44; Cant&#243;n R&#44; editores&#46; Procedimientos en Microbiolog&#237;a Cl&#237;nica&#46; Recomendaciones de la Sociedad Espa&#241;ola de Enfermedades Infecciosas y Microbiolog&#237;a Cl&#237;nica&#46; 2011 &#91;consultado Feb 2016&#93;&#46; Disponible en&#58; <a href="http://www.seimc.org/documentos/protocolos/microbiologia/cap38indice.htm">http&#58;&#47;&#47;www&#46;seimc&#46;org&#47;documentos&#47;protocolos&#47;microbiologia&#47;cap38indice&#46;htm</a>"
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reappraisal of community-acquired bacteremia&#58; A proposal of a new classification for the spectrum of acquisition of bacteremia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Y&#46; Siegman-Igra"
                            1 => "B&#46; Fourer"
                            2 => "R&#46; Orni-Wasserlauf"
                            3 => "Y&#46; Golan"
                            4 => "A&#46; Noy"
                            5 => "D&#46; Schwartz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/339809"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Infect Dis"
                        "fecha" => "2002"
                        "volumen" => "34"
                        "paginaInicial" => "1431"
                        "paginaFinal" => "1439"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12015688"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Estudio Nacional de Vigilancia de Infecci&#243;n Nosocomial&#46; ENVIN-HELICS 2013 &#91;consultado Feb 2016&#93;&#46; Disponible en&#58; <a href="http://hws.vhebron.net/envin-helics/index.asp">http&#58;&#47;&#47;hws&#46;vhebron&#46;net&#47;envin-helics&#47;index&#46;asp</a>"
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units&#58; The EUROBACT International Cohort Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Tabah"
                            1 => "D&#46; Koulenti"
                            2 => "K&#46; Laupland"
                            3 => "B&#46; Misset"
                            4 => "J&#46; Valles"
                            5 => "F&#46; Bruzzi de Carvalho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00134-012-2695-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med"
                        "fecha" => "2012"
                        "volumen" => "38"
                        "paginaInicial" => "1930"
                        "paginaFinal" => "1945"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23011531"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Estudio de prevalencia de las infecciones nosocomiales en Espa&#241;a&#46; EPINE-EPPS 2013 &#91;consultado Feb 2016&#93;&#46; Disponible en&#58;<a href="http://hws.vhebron.net/epine/Descargas/EPINE-EPPS2013%20Informe%20Global%20de%20Espa%C3%B1a%20Resumen.pdf">http&#58;&#47;&#47;hws&#46;vhebron&#46;net&#47;epine&#47;Descargas&#47;EPINE-EPPS2013&#37;20Informe&#37;20Global&#37;20de&#37;20Espa&#37;C3&#37;B1a&#37;20Resumen&#46;pdf</a>"
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "European Antimicrobial Resistance Surveillance network &#40;EARS-net&#41; &#91;consultado Feb 2016&#93;&#46; Disponible en&#58; <a href="http://ecdc.europa.eu/en/activities/surveillance/EARSNet/database/Pages/database.aspx">http&#58;&#47;&#47;ecdc&#46;europa&#46;eu&#47;en&#47;activities&#47;surveillance&#47;EARSNet&#47;database&#47;Pages&#47;database&#46;aspx</a>"
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology and risk factors for ESBL-producing Klebsiella pneumoniae&#58; A case control study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46; Demirdag"
                            1 => "S&#46; Hosoglu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dev Ctries"
                        "fecha" => "2010"
                        "volumen" => "4"
                        "paginaInicial" => "717"
                        "paginaFinal" => "722"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21252449"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk factors for the acquisition of carbapenem-resistant Escherichia coli among hospitalized patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;H&#46; Jeon"
                            1 => "S&#46;H&#46; Choi"
                            2 => "Y&#46;G&#46; Kwak"
                            3 => "J&#46;W&#46; Chung"
                            4 => "S&#46;O&#46; Lee"
                            5 => "J&#46;Y&#46; Jeong"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.diagmicrobio.2008.08.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Diagn Microbiol Infect Dis"
                        "fecha" => "2008"
                        "volumen" => "62"
                        "paginaInicial" => "402"
                        "paginaFinal" => "406"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18993012"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk factors for antimicrobial resistance and influence of resistance on mortality in patients with bloodstream infection caused by Pseudomonas aeruginosa"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;I&#46; Kang"
                            1 => "S&#46;H&#46; Kim"
                            2 => "W&#46;B&#46; Park"
                            3 => "W&#46;B&#46; Lee"
                            4 => "H&#46;B&#46; Kim"
                            5 => "E&#46;C&#46; Kim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1089/mdr.2005.11.68"
                      "Revista" => array:6 [
                        "tituloSerie" => "Microb Drug Resist"
                        "fecha" => "2005"
                        "volumen" => "11"
                        "paginaInicial" => "68"
                        "paginaFinal" => "74"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15770098"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of antibiotic-resistant Gram-negative bacilli infections on outcome in hospitalized patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46;P&#46; Raymond"
                            1 => "S&#46;J&#46; Pelletier"
                            2 => "T&#46;D&#46; Crabtree"
                            3 => "H&#46;L&#46; Evans"
                            4 => "T&#46;L&#46; Pruett"
                            5 => "R&#46;G&#46; Sawyer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.CCM.0000060015.77443.31"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med&#46;"
                        "fecha" => "2003"
                        "volumen" => "31"
                        "paginaInicial" => "1035"
                        "paginaFinal" => "1041"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12682469"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bacteremia caused by Escherichia coli producing extended-spectrum beta-lactamase&#58; A case-control study of risk factors and outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Ho PL1"
                            1 => "W&#46;M&#46; Chan"
                            2 => "K&#46;W&#46; Tsang"
                            3 => "S&#46;S&#46; Wong"
                            4 => "K&#46; Young"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Scand J Infect Dis&#46;"
                        "fecha" => "2002"
                        "volumen" => "34"
                        "paginaInicial" => "567"
                        "paginaFinal" => "573"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12238570"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
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