Manejo farmacológico en el síndrome anorexia-caquexia

Castejón, Esperanza; Lambruschini, Nilo; Meavilla, Silvia María; Catalán, Natalia

Información del artículo

Resumen

Bibliografía

La caquexia es un síndrome metabólico complejo caracterizado por anorexia y pérdida de peso que aparece en enfermedades crónicas como el cáncer o la infección por el VIH. La desnutrición en pacientes oncológicos se ha relacionado con peor tolerancia al tratamiento, menor respuesta al tratamiento y peor calidad de vida. Se han empleado distintos fármacos contra la caquexia en pacientes oncológicos. El objetivo de esta revisión es conocer los fármacos disponibles en la actualidad, su mecanismo de acción y sus efectos adversos.

Palabras clave:

Nutrición

Cáncer

Neoplasias

Anorexia

Caquexia

Farmacoterapia

Cachexia is a complex syndrome associated with anorexia and weight loss. This syndrome is very common in chronic diseases such as cancer or HIV diseases. Malnutrition in oncology patients is associated with poorer treatment tolerance, poorer outcomes and a poorer quality of life. The challenge for clinicians is to know how best to manage the symptoms of weight loss and anorexia for optimal patient outcomes. Different treatments have been used in this syndrome. The aim of the present article is to review the different therapeutic approaches and emerging drugs that have been designed to combat and counteract cachexia associated with cancer.

Keywords:

Nutrition

Cancer

Neoplasms

Anorexia

Cachexia

Drug therapy

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