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Available online 1 July 2024
Clinical and microbiological characteristics of Eggerthella lenta causing bacteremia
Características clínicas y microbiológicas de Eggerthella lenta como causa de bacteriemia
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Domingo Fernández Vecillaa,
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domingofvec@gmail.com

Corresponding author.
, Mikel Joseba Urrutikoetxea Gutiérrezb,c, Mary Paz Roche Matheusb,c, Felicitas Elena Calvo Murob,c, José Luis Díaz de Tuesta del Arcob,c
a Sierrallana Hospital, Microbiology Service, Cantabria, Spain
b Basurto University Hospital, Clinical Microbiology Service, Bilbao, Basque Country, Spain
c Biocruces Bizkaia Health Research Institute, Barakaldo, Basque Country, Spain
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Table 1. Summary of bacteremia cases.
Table 2. Antimicrobial susceptibility test results (MIC values are provided).
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Abstract

Eggerthella lenta is an obligate anaerobic, Gram-positive bacilli, belonging to the human microbiota of gastrointestinal and female reproductive tracts, oral cavity and prostate gland. In this article, we aim to describe clinical and microbiological characteristics of seven E. lenta strains causing bacteremia. We conducted a descriptive retrospective study including all E. lenta strains causing bacteremia, from February 2019 to August 2023 at the Basurto University Hospital. Seven patients were included in the study with a mean age of 72.7 years. Six patients presented risk factors associated with bacterial infections. All patients were admitted to the hospital because of suspicious of bloodstream infection associated with abdominal symptoms for intravenous antibiotic treatment. Four E. lenta isolates were resistant to penicillin, while all isolates presented high MICs to piperacillin/tazobactam and low MICs to amoxicillin/clavulanic acid. All patients recovered without no complications.

Keywords:
Anaerobes
Eggerthella lenta
Bacteremia
MALDI-TOF MS
Resumen

Eggerthella lenta es un bacilo grampositivo, anaerobio obligado, que pertenece a la microbiota humana de los tractos gastrointestinal y reproductor femenino, la cavidad oral y la glándula prostática. En este artículo pretendemos describir las características clínicas y microbiológicas de siete E. lenta causantes de bacteriemia. Se realizó un estudio descriptivo retrospectivo, que incluyó todas las cepas de E. lenta causantes de bacteriemia, desde febrero de 2019 hasta agosto de 2023 en el Hospital Universitario de Basurto. Se incluyeron siete pacientes en el estudio, con una edad media de 72,7 años. Seis pacientes presentaban factores de riesgo asociados a infecciones bacterianas. Todos los pacientes ingresaron en el hospital por sospecha de bacteriemia y con síntomas abdominales para recibir antibiótico intravenoso. Cuatro aislados de E. lenta eran resistentes a la penicilina, mientras que todos los aislados presentaban CMI altas a la piperacilina/tazobactam y CMI bajas a la amoxicilina/ácido clavulánico. Los pacientes se recuperaron sin complicaciones.

Palabras clave:
Anaerobios
Eggerthella lenta
Bacteriemia
MALDI-TOF MS

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