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Inicio Medicina Clínica (English Edition) Incidence and mortality of osteomielitis in Spain according to the basic minimum...
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Vol. 153. Issue 11.
Pages 418-423 (December 2019)
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Vol. 153. Issue 11.
Pages 418-423 (December 2019)
Original article
Incidence and mortality of osteomielitis in Spain according to the basic minimum data set
Incidencia y mortalidad de la osteomielitis en España según el conjunto mínimo básico de datos
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8
Pilar López del Pino
Corresponding author
mapilopi@hotmail.com

Corresponding author.
, Antonio Guerrero Espejo
Facultad de Medicina, Universidad Católica de Valencia, Valencia, Spain
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Tables (2)
Table 1. Percentages of deaths in patients admitted for osteomyelitis.
Table 2. Results of the bivariate and multivariate analysis (logistic regression model) of variables associated with hospital mortality in patients admitted for osteomyelitis.
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Abstract
Background and objectives

To understand the incidence and mortality of patients hospitalised for osteomyelitis in Spain.

Material and method

An observational study of the population admitted to Spanish hospitals with a primary diagnosis of osteomyelitis, according to the minimum basic data set for hospital discharge (MBDS), between 1997–2014 (29,290 cases) was carried out.

Results

The incidence was 3.85 cases/100,000 inhabitants per year. Relative risk for males was 2.02.

In-hospital mortality was 1.72% (99% CI: 1.4–1.93). The mortality of osteomyelitis associated to septicemia reached 27.12% (99%CI: 20.5–35), that of infection by methicillin-resistant Staphylococcus aureus (MRSA) was 5.5% (99% CI: 2.18–13.2), and that of those aged over 64 was 4.65% (99% CI: 3.89–5.0).

In a multivariate analysis, mortality was associated independently with a diagnosis of septicemia, acute osteomyelitis, urgent admissions, infection with MRSA, being over 64 and female.

Conclusions

The incidence of hospitalisations for osteomyelitis in Spain is substantial. Sepsis, being over 64 and MRSA infection are important risk factors for death.

Keywords:
Osteomyelitis
Incidence
Mortality
Spain
Epidemiology
Resumen
Fundamento y objetivos

Conocer la incidencia y mortalidad de pacientes hospitalizados por osteomielitis en España.

Material y método

Se realizó un estudio observacional de población ingresada con diagnóstico principal de osteomielitis en hospitales españoles según el conjunto mínimo de datos al alta hospitalaria, entre 1997-2014 (29.290 casos).

Resultados

La incidencia de ingresos por osteomielitis fue de 3,85 (IC 99%: 3,79-3,91) casos/100.000 habitantes y año. El riesgo relativo de los hombres fue de 2,02.

La mortalidad intrahospitalaria fue del 1,72% (IC 99%: 1,4 -1,93). La mortalidad de la osteomielitis asociada a septicemia alcanzó el 2,712% (IC 99%: 20,5-35), la de la infección por Staphylococcus aureus resistente a meticilina (MRSA) el 5,5% (IC 99%: 2,18-13,2) y la de mayores de 64 años el 4,65% (IC 99%: 3,89-5,0).

En el análisis multivariante la mortalidad se asoció de forma independiente a los diagnósticos de septicemia, osteomielitis aguda, ingresos urgentes, infección por MRSA, mayores de 64 años, comorbilidad y mujeres (p<0,001).

Conclusiones

La incidencia de hospitalizaciones por osteomielitis en España es sustancial. La sepsis, la edad superior a los 64 años e infección por MRSA son factores importantes de riesgo de muerte.

Palabras clave:
Osteomielitis
Incidencia
Mortalidad
España
Epidemiología

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