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Case report
Erector spinae plane block for radical mastectomy: A new indication?
Bloqueo en el plano del músculo erector de la columna para mastectomía radical: ¿una nueva indicación?
M. Veiga
Corresponding author
nocas_veiga@hotmail.com

Corresponding author.
, D. Costa, I. Brazão
Servicio de Anestesiología, Hospital Central do Funchal, Funchal, Portugal
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Radical mastectomy is a surgical procedure that is often associated with moderate to severe post-operative pain for which opioids are usually prescribed&#46; Effective pain management preserves the immune system by suppressing the stress response to surgery and reducing the need for opioids in the post-operative period&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a> Acute pain management after mastectomy reduces the incidence of chronic pain&#46; Regional pain management techniques improve acute pain management and prevent the appearance of chronic pain&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The erector spinae plane block &#40;ESB&#41; was firstly described in September 2016&#44; by Forero et al&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">3</span></a> in the context of chronic thoracic neuropathic pain and pain management during thoracoscopic surgery&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">We describe a case involving left radical mastectomy under combined anesthesia &#40;ESB and general anesthesia&#41;&#44; discussing the follow up measures and the advantages of the technique&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Clinical case</span><p id="par0020" class="elsevierStylePara elsevierViewall">The patient was a 40-year-old woman&#44; weight 81<span class="elsevierStyleHsp" style=""></span>kg&#44; height 168<span class="elsevierStyleHsp" style=""></span>cm&#44; non-smoker&#44; who was scheduled for left radical mastectomy due to breast cancer after a course of chemotherapy&#46; The preoperative evaluation revealed no other pathology&#46; The patient had no regular medication&#44; no allergies&#44; and no history of alcohol consumption&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">In view of the potential immunosuppressive effect of opioids and their negative impact on cancer surgery outcomes described by Sacerdote et al&#46;&#44; <a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">4</span></a> albeit unconfirmed in humans according to Cronin-Fenton et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">5</span></a> we decided to perform ESB before the induction of general anesthesia&#46; This combined technique has several advantages&#58; it reduces intra-operative opioid consumption&#44; avoids post-operative opioid consumption&#44; allows mobilization of the left arm &#40;ipsilateral to the resected axillary ganglion&#41;&#44; and reduces the risk of post-operative chronic pain&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Monitoring was started and the ESB was performed in the block room under ultrasound guidance &#40;S-Nerve&#44; SonoSite&#44; USA&#41;&#46; The patient was placed in the sitting position and the spinous process of the fifth thoracic vertebra &#40;T5&#41; was identified with the probe in longitudinal position &#40;HFL50x&#44; SonoSite&#44; USA&#41;&#46; We proceeded with left lateral scanning&#44; searching for the T5 transverse process &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Once identified&#44; a 5<span class="elsevierStyleHsp" style=""></span>cm needle &#40;Echoplex&#44; Vygon&#44; France&#41; was inserted in plane in a cephalad to caudal direction until the tip lay in the interfascial plane between rhomboid major and erector spinae muscles&#44; at the level of T5 &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; Once in place&#44; 20<span class="elsevierStyleHsp" style=""></span>ml of levobupivacaine 0&#46;5&#37; were injected under the erector spinae muscle &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; The local anesthetic spread in a longitudinal pattern&#46; After performing the block&#44; the patient was positioned in the supine position&#46; Thirty minutes later&#44; the level of blockade was evaluated&#46; The area of diminished sensation to pinprick extended from T2 to T8 in the posterior and anterior chest wall&#46; The inferior axillary region was also anaesthetized&#44; with diminished sensation to pinprick &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#44; adapted from <span class="elsevierStyleItalic">Netter&#39;s Clinical Anatomy</span><a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">6</span></a>&#41;&#46; After confirmation of the blockade&#44; induction of general anesthesia was performed&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Intravenous induction was performed with 60<span class="elsevierStyleHsp" style=""></span>mg of lidocaine&#44; 100<span class="elsevierStyleHsp" style=""></span>mcg of fentanyl and 150<span class="elsevierStyleHsp" style=""></span>mg of propofol&#46; A supraglottic device was inserted and anesthesia was maintained with sevoflurane&#46; No further doses of fentanyl were required&#44; and the patient remained stable throughout the procedure&#46; Thirty minutes before the end of surgery&#44; 30<span class="elsevierStyleHsp" style=""></span>mg of ketorolac&#44; 1<span class="elsevierStyleHsp" style=""></span>g of paracetamol and 4<span class="elsevierStyleHsp" style=""></span>mg of ondansetron were administered&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">After emergence&#44; the patient was transferred to the post anesthesia care unit &#40;PACU&#41;&#44; where she remained hemodynamically stable&#46; She reported upper axillary pain of 4 on a 10-point numerical rating scale &#40;NRS&#41;&#44; and 2<span class="elsevierStyleHsp" style=""></span>g of metamizole were administered&#46; At discharge&#44; 1<span class="elsevierStyleHsp" style=""></span>h after transfer to the PACU&#44; pain was NRS 1&#46; For post-operative analgesia&#44; 30<span class="elsevierStyleHsp" style=""></span>mg of ketorolac every 8<span class="elsevierStyleHsp" style=""></span>h for 24<span class="elsevierStyleHsp" style=""></span>h and 1<span class="elsevierStyleHsp" style=""></span>g Paracetamol every 8<span class="elsevierStyleHsp" style=""></span>h for 48<span class="elsevierStyleHsp" style=""></span>h were prescribed&#46; If pain reached NRS<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>5&#44; 2<span class="elsevierStyleHsp" style=""></span>g of metamizole could be administered&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">The patient was evaluated at 24 and 48<span class="elsevierStyleHsp" style=""></span>h to assess pain management and sleep quality&#46; The patient reported a pain of NRS 0 on movement and at rest&#44; with full range of movement in the left arm&#46; Pain was evaluated every 4<span class="elsevierStyleHsp" style=""></span>h&#44; and no rescue analgesia &#40;metamizole&#41; was required during her stay&#46; The patient reported no insomnia at any time&#44; and no hypnotics were required&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion</span><p id="par0050" class="elsevierStylePara elsevierViewall">ESB is a simple regional anesthesia technique with a good safety profile&#46; After it was first described by Forero et el&#46;&#44; studies evaluating this blockade in various surgical procedures have been published&#46; In 2017&#44; Hamilton et al&#46; described a case of ESB for pain management of several rib fracture&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">6</span></a> In the same year&#44; Chin et al&#46; described the analgesic effect of ESB for ventral hernia repair&#44; in this case performed at the seventh thoracic vertebrae &#40;T7&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">7</span></a> In May 2017&#44; the first experience with ESB for breast surgery was described in the case of a patient undergoing breast implant replacement&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">8</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">In 2015&#44; Rou&#233; et al&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">9</span></a> described an intercostal&#47;paraspinal block technique for thoracic surgery that resembles ESB&#46; However&#44; ESB uses a more medial approach to a point upstream of the division of the ventral and dorsal rami of the thoracic nerves&#44; where there are no structures at risk of needle injury in the immediate vicinity&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">Anesthesia and surgery affect the immune response&#46; Opioid-induced changes in the immune system have been reported in HIV positive patients and intravenous drug users&#46; The effect of these drugs in patients receiving chemotherapy treatment and in the postoperative period is not fully understood&#44; but is likely to be detrimental&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">4</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">To the best of our knowledge&#44; based on the results of a search for similar studies in the literature&#44; this is the first description of the use of ESB in radical mastectomy&#46; Further studies are needed to confirm the efficacy of this technique&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusion</span><p id="par0070" class="elsevierStylePara elsevierViewall">ESB is a novel&#44; easy to use technique with a good safety profile that has attracted much attention in recent months&#44; and appears to be a good regional technique for radical mastectomy&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">The duration of analgesia&#44; the extent of the blockade &#40;including the axillar region&#41;&#44; and the possibility of opioid avoidance in the postoperative period appear to favor the use of this technique in oncologic breast surgery&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Ethical disclosures</span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Protection of human and animal subjects</span><p id="par0080" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Confidentiality of data</span><p id="par0085" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Right to privacy and informed consent</span><p id="par0090" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Conflict of interests</span><p id="par0095" class="elsevierStylePara elsevierViewall">The authors declare no conflict of interests&#46;</p></span></span>"
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        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The erector spinae plane block is a technique recently described by Forero et al&#46; in September 2016&#46; It has applications in the control of chronic pain with neuropathic component of the chest wall&#44; and for pain control in thoracoscopic surgery&#46; In this article&#44; we describe the use of this technique as part of a multimodal analgesic approach in a 40-year-old woman&#44; who underwent radical mastectomy due to breast cancer&#46; By performing this block before anesthetic induction&#44; we have achieved an opioid sparing effect&#44; avoiding a possible immunomodulatory effect&#44; although not yet proven in humans&#46; During hospitalization&#44; the patient reported no pain &#40;0&#47;10 in numeric scale&#41;&#44; without resorting to rescue analgesia&#46; The easy&#44; fast and safe execution of erector spinae plane block makes it a promising technique in the context of surgical pain during radical mastectomy&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El bloqueo de la fascia del m&#250;sculo erector de la columna es una t&#233;cnica recientemente descrita por Forero et al&#46; en septiembre de 2016&#46; Tiene aplicaciones en el control del dolor cr&#243;nico con componente neurop&#225;tico de la pared tor&#225;cica&#44; y para el control del dolor en cirug&#237;a toracosc&#243;pica&#46; En este art&#237;culo&#44; describimos el uso de esta t&#233;cnica como parte de un enfoque analg&#233;sico multimodal en una mujer de 40 a&#241;os&#44; que fue sometida a una mastectom&#237;a radical a causa de un c&#225;ncer de mama&#46; Al realizar este bloqueo antes de la inducci&#243;n anest&#233;sica&#44; conseguimos un efecto ahorrador de opioides&#44; evitando el posible efecto inmunomodulador&#44; que todav&#237;a no est&#225; comprobado en humanos&#46; Durante la hospitalizaci&#243;n&#44; la paciente no report&#243; dolor &#40;0&#47;10 en escala num&#233;rica&#41;&#44; sin recurrir a analgesia de rescate&#46; La ejecuci&#243;n f&#225;cil&#44; r&#225;pida y segura del bloqueo de la fascia del m&#250;sculo erector de la columna hace que esta sea una t&#233;cnica prometedora en el contexto del dolor quir&#250;rgico durante la mastectom&#237;a radical&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Veiga M&#44; Costa D&#44; Braz&#227;o I&#46; Bloqueo en el plano del m&#250;sculo erector de la columna para mastectom&#237;a radical&#58; &#191;una nueva indicaci&#243;n&#63; Rev Esp Anestesiol Reanim&#46; 2018&#59;65&#58;112&#8211;115&#46;</p>"
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                            1 => "A&#46; El-Rahman"
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                            0 => "M&#46; Forero"
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                  "contribucion" => array:1 [
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                          "etal" => false
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                            0 => "K&#46;J&#46; Chin"
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Article information
ISSN: 23411929
Original language: English
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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos