We would like to share ideas on the publication “Rapid antigen tests for the detection of SARS-CoV-2: A narrative review”.1 Aguilar-Shea et al. concluded that “Antigen tests have become a very useful and validated tool for controlling the spread of COVID-19 …”.1 We agree that rapid antigen test is useful for rapid diagnosis of COVID-19. Since it can be used as point of care test, the rapid test is proved usefulness for mass screening during outbreak.2 However, the predictive value of the diagnostic test for COVID-19 depends on the prevalence of disease.3 Hence, a re-evaluation of diagnostic property of the test at different situations of outbreak is necessary. For rapid antigen test, the effect of new emerging SARS CoV2 variant on diagnostic property is another interesting issue. In a recent report, Bourassa et al. found that some mutants could escape some antigen test and this is an important issue for evaluation of any available rapid antigen test.4
Conflict of interestNone declared.
