Trastornos motores y endoscópicos en sujetos obesos asintomáticos

Quiróz-Guadarrama, C.D.; Rojano-Rodríguez, M.E.; Herrera-Esquivel, J.J.; Lárraga, O.A.; Romero-Loera, L.S.; Cárdenas-Lailson, E.; Dionisio, R.; del Río-Suárez, I.; Morales-Vargas, J.M.; Mucio, M.

doi:10.1016/j.endomx.2013.10.001

Información del artículo

Resumen

Bibliografía

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Estadísticas

Resumen

Introducción

La obesidad es un factor de riesgo para el desarrollo de enfermedad por reflujo gastroesofágico. El objetivo de este estudio fue comparar los hallazgos endoscópicos y manométricos entre pacientes con obesidad y sujetos no obesos asintomáticos.

Material y métodos

Se realizó un estudio prospectivo, comparativo con 56 pacientes con obesidad, sin síntomas de reflujo, con índice de DeMeester < 14.7, los cuales fueron comparados con 30 sujetos voluntarios no obesos asintomáticos.

Resultados

la presencia de hernia hiatal y esofagitis fue más frecuente en el grupo de pacientes con obesidad (hernia hiatal GI 28%, GII 10%; p<0.05) (esofagitis GI 8.9%, GII 0%). La presión del esfínter esofágico inferior fue menor en los sujetos obesos (GI 7.18 ± 3.78, GII 12.84 ± 4.82; p<0.05). Se identificó una fuerte asociación entre la obesidad y la dismotilidad del cuerpo esofágico (RM=7; IC 95%=2.73-22.88). En conclusión, los pacientes con obesidad exhiben mayor frecuencia de hernia hiatal y esofagitis, así como disminución de la presión del esfínter esofágico inferior aún cuando son asintomáticos para reflujo. Existe una fuerte asociación entre la dismotilidad del cuerpo esofágico y la obesidad.

Palabras clave:

obesidad

Motilidad esofágica

Enfermedad por reflujo gastroesofágico

Hernia hiatal

Esfínter esofágico inferior

México.

Abstract

Introduction

Obesity is associated with gastroesophageal reflux. The aim of this prospective study was to compare endoscopic and manometric findings in asymptomatic obese patients and compare it to non-obese individuals.

Material and methods

A prospective, comparative study was conducted with 56 obese patients without GERD symptoms and index DeMeester reflux < 14.7 were compared to 30 asymptomatic no-obese individuals.

Results

the presence of hiatal hernia and esophagitis was more frequent in the group of obese patients (hiatal hernia GI 28%, GI GII 10%; p<0.05) (esophagitis GI 8.9%, GII 0%). The lower esophageal sphincter pressure was lower in obese subjects (GI 7.18 ± 3.78, GII 12.84 ± 4.82; p<0.05). We identified a strong association between obesity and esophageal body dysmotility (OR=7; CI 95%=2.73-22.88). In conclusion, obese patients show increased frequency of hiatal hernia and esophagitis, as well as decreased lower esophageal sphincter pressure even when they are asymptomatic for reflux. There is a strong association between esophageal body dysmotility and obesity

Keywords:

obesity

Esophageal motility

Gastroesophageal reflux

Hiatal hernia

lower esophageal sphincter

Mexico.

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