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Inicio Revista Colombiana de Cardiología Lecciones aprendidas de dos grandes estudios epidemiológicos de enfermedades ca...
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Vol. 17. Núm. 5.
Páginas 195-200 (septiembre - octubre 2010)
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Vol. 17. Núm. 5.
Páginas 195-200 (septiembre - octubre 2010)
Open Access
Lecciones aprendidas de dos grandes estudios epidemiológicos de enfermedades cardio-cerebrovasculares en las que ha participado colombia
Lessons learned from two large epidemiological studies of cardiovascular and cerebrovascular diseases in which colombia took part
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2518
Patricio López-Jaramillo1,2,
Autor para correspondencia
jplopezj@hotmail.com
investigaciones@foscal.com.co

Correspondencia: Fundación Oftalmológica de Santander-Clínica Caros Ardila Lulle (FOSCAL), Torre Milton Salazar, primer piso, entrada Oftalmología y Farmacia. Calle 155A No. 23-09, Urbanización El Bosque, Floridablanca-Santander. Teléfonos. (57-7) 6384160 - 63860000 Ext. 2509-2510.
, José López-López3
1 Facultad de Medicina, Universidad de Santander, Bucaramanga, Colombia
2 Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lulle. Bucaramanga, Colombia
3 Facultad de Medicina, Universidad Autónoma de Bucaramanga. Bucaramanga, Colombia
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Resumen

Dos recientes estudios epidemiológicos de gran envergadura en los que participó Colombia, el INTERHEART y el INTERSTROKE, demostraron que en Latinoamérica en general y en Colombia en particular, el principal factor de riesgo para la presentación de infarto agudo del miocardio y accidente cerebro vascular isquémico y hemorrágico es la obesidad abdominal, a diferencia del resto del mundo donde el principal factor de riesgo fue el aumento en las concentraciones plasmáticas del colesterol total y del colesterol LDL, en el primer caso, y la hipertensión arterial, en el segundo. Estos datos dan soporte a la propuesta de que en Latinoamérica la transición rápida de los modelos económicos experimentados en los últimos años junto con la urbanización acelerada son la causa del explosivo aumento de la obesidad abdominal, la diabetes mellitus tipo 2 y las enfermedades cardio-cerebro-vasculares.

Palabras clave:
diferencias regionales
obesidad abdominal
inflamación de bajo grado
Abstract

Two recent large-scale epidemiological studies, INTERHEART and INTERSTROKE in which Colombia took part, demonstrated that in Latin America in general and particularly in Colombia, the main risk factor for the presentation of acute myocardial infarction and ischemic, and hemorrhagic stroke was the abdominal obesity in contrast to the rest of the world where the main risk factor was increase in plasma concentrations of total cholesterol and LDL-cholesterol for myocardial infarction, and hypertension for stroke. These data give support to the proposal that in Latin America the rapid transition in economic models experienced in the last years together with the fast urbanization has led to an explosive increase in abdominal obesity, diabetes mellitus type 2, and cardiovascular and cerebrovascular diseases.

Key words:
regional differences
abdominal obesity
low grade inflammation
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Bibliografía
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Is C-reactive protein an independent risk factor for essential hypertension?.
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Copyright © 2010. Sociedad Colombiana de Cardiología y Cirugía Cardiovascular
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