Abstracts from XVII Mexican Congress of Hepatology
More infoTo present two clinical cases of patients with autoimmune hepatitis (AIH). After infection by SARS-COV2, presented reactivation of the disease.
Materials and methods42-year-old female with a history of celiac disease, choledocholithiasis, Arterial hypertension and CACU. Autoimmune hepatitis since 2012 treated with Prednisone, ursodeoxycolic acid and mycophenolic Ac. In March 2022, she presented infection by SARS COV-2 and relapse of AIH due to elevated transaminases; remission was reinduced with prednisone, showing biochemical improvement
48-year-old male history of psoriasis diagnosed with AIH in 2018 under treatment with Prednisone and Azathioprine. In February 2022, he presented a serious infection by SARS-Cov 2, restarting the remission reinduction scheme with prednisone and Azathioprine.
DiscussionIn the bibliography consulted, there are no reports about the reactivation of the disease after infection by SARS-CoV-2, although there is a case report for autoimmune hepatitis and an autoimmune hepatitis overlap syndrome/primary biliary cholangitis triggered by COVID-19.
ConclusionsThe spectrum of affectations after the pandemic by SARSCOV-2 is still wide, so we consider it important to expose these cases where the history of the infection in the face of an exacerbation by SARSCOV-2; in our experience, remission was reinduced with prednisone and azathioprine of according to international schemes, with good response from patients. We consider it important to report these cases since there is an association between AIH and viral infections such as Epsteinbar, so there may be a clear association between Sarc-cov2 infection and relapse.
FundingThe resources used in this study were from the hospital without any additional financing
Declaration of interestThe authors declare no potential conflicts of interest.
