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4776
The pituitary gland in SARS-CoV-2 infections, vaccinations, and post-COVID syndrome
Josef Finsterer, Fulvio Alexandre Scorza
Clinics. 2023;78C:100157
4776
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3686
Long post-COVID-vaccination syndrome manifesting as temperature-sensitive myalgia and hyper-CKemia
Josef Finsterer, Carla A. Scorza, Fulvio A. Scorza
Clinics. 2023;78C:100175
3686
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3609
Complete blood count and C-reactive protein to predict positive blood culture among neonates using machine learning algorithms
Felipe Yu Matsushita, Vera Lúcia Jornada Krebs, Werther Brunow de Carvalho
Clinics. 2023;78C:100148
3609
Highlights

  • It can take days to get the result of blood culture.

  • CBC and CRP are readily available exams and could be used to predict blood culture.

  • ML algorithms based on CBC and CRP couldn't predict neonatal blood culture positivity.

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3110
“Scientific Evidence for Homeopathy”
Marcus Zulian Teixeira
Clinics. 2023;78C:100255
3110
Highlights

  • Homeopathy is based on heterodox and complementary four scientific assumptions.

  • Pseudosceptics deny these assumptions and any scientific evidence that proves them.

  • The dossier describes hundreds of clinical and experimental studies in homeopathy.

  • The dossier demystifies the fallacy that “there isn't scientific evidence for homeopathy”.

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3059
Neurophysics: Understanding brain activity with modeling complex systems mathematics
Fulvio A. Scorza, Ana C. Fiorini, Antônio M. Rodrigues, Carla A. Scorza, Gabriel D. Vilallonga, Marcelo A. Moret, Tarcísio M. Rocha Filho, Josef Finsterer, Antônio-Carlos G. de Almeida
Clinics. 2023;78C:100158
3059
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2888
SARS-CoV-2 vaccination complicated by small fiber neuropathy, mast cell activation syndrome, and pericarditis
Danice Hertz, Fulvio Alexandre Scorza, Ana Claudia Fiorini, Josef Finsterer
Clinics. 2023;78C:100304
2888
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2191
Endoscopic Biliary Darinage (EBD) versus Percutaneous Transhepatic Biliary Drainage (PTBD) for biliary drainage in patients with Perihilar Cholangiocarcinoma (PCCA): A systematic review and meta-analysis
Caroline Flaksbaum Moll, Diogo Turiani Hourneaux de Moura, Igor Braga Ribeiro, Igor Mendoça Proença, Epifanio Silvino do Monte Junior, Sergio A. Sánchez-Luna, Maria Fernanda Shinin Merchán, Josselyn Mariana Vera Intriago, ... Eduardo Guimarães Hourneaux de Moura
Clinics. 2023;78C:100163
2191
Highlights

  • There is no consensus about which method is preferred for biliary drainage for Perihilar Cholangiocarcinoma (PCCA).

  • Endoscopic retrograde cholangiopancreatography (EBD) or Percutaneous Transhepatic Biliary Drainage (PTBD) are options of choice.

  • PTBD is superior to EBD regarding crossover rate, overall post-drainage complications, and post-drainage pancreatitis.

  • EBD is superior to PTBD when it comes to hospital length of stay.

  • For the palliation of PCCA, PTBD is superior to EBD in terms of clinical success and post-drainage cholangitis.

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1972
Venous thromboembolism risk score during hospitalization in pregnancy: results of 10694 prospective evaluations in a clinical trial
Venina Isabel Poço Viana Leme de Barros, Ana Maria Kondo Igai, Fernanda Spadotto Baptista, Maria Rita de Figueiredo Lemos Bortolotto, Stela Verzinhasse Peres, Rossana Pulcinelli Vieira Francisco
Clinics. 2023;78C:100230
1972
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1812
Perianal fistulizing Crohn's disease is associated with a higher prevalence of HPV in the anorectal fistula tract. A comparative study
Lucas Rodrigues Boarini, Carlos Walter Sobrado, Giana Rabello Mota, Luisa Lina Villa, Idblan Carvalho de Albuquerque, Natalia Sousa Freitas Queiroz, Carolina Bortolozzo Graciolli Facanali, Sidney Roberto Nadal, Ivan Cecconello
Clinics. 2023;78C:100219
1812
Highlights

  • Perianal Crohn's disease is the main risk factor for anal cancer in IBD patients.

  • Perianal Crohn's disease patient has a chance of HPV 3.29 time higher than control.

  • High risk HPV is numerically twice as prevalent in perianal Crohn's disease patient.

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1744
Small fiber neuropathy with long-term, multifocal paresthesias after a SARS-CoV-2 vaccination
Josef Finsterer, Fulvio Alexandre Scorza, Carla Alexandra Scorza, Antonio-Carlos G. de Almeida
Clinics. 2023;78C:100186
1744
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1668
Changes in clinical and CT manifestations related to liver abscesses in patients with vs. without basic diabetes mellitus before and after CT-guided interventional therapy: An observational study
Yuxiang Chen, Xunfu Lai, Yuping Zhu, Mengting Wang, Yulin He
Clinics. 2023;78C:100164
1668
Highlights

  • Liver abscess patients with diabetes mellitus have featured presentations.

  • Liver abscess patients with diabetes mellitus have featured changes after therapy.

  • Liver abscess patients with diabetes mellitus cannot have a better therapeutic effect.

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1661
Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non‑small‑cell lung cancer: A meta analysis
Min Yi, Ting He, Kaijin Wang, Yonggang Wei
Clinics. 2023;78C:100152
1661
Highlights

  • This meta-analysis shows that gefitinib plus chemotherapy showed significantly better efficacy in improving objective response rate, disease control rate, progression-free survival, and OS as compared with gefitinib alone.

  • Similar efficacy of gefitinib plus chemotherapy is found in the sub-population with positive EGFR mutation.

  • The toxicity of gefitinib plus chemotherapy is also increased but within clinical management.

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1570
The effect of sperm DNA fragmentation on in vitro fertilization outcomes of unexplained infertility
Qingxin Wang, Xiaoling Gu, Yannan Chen, Minyan Yu, Lingna Peng, Shuping Zhong, Xia Wang, Jinxing Lv
Clinics. 2023;78C:100261
1570
Highlights

  • Infertility is caused by heterogeneous risks, but most of them are unexplained.

  • Sperm DFI diagnostic value was controversial as not rule out male sperm parameters.

  • Whether DFI was a useful indicator for embryologists and clinicians in UEI couples.

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1485
COVID-19 in children and adolescents with neuroimmunological disorders
Ingrid Lacerda Pessoa, Renata Barbosa Paolilo, José Albino da Paz
Clinics. 2023;78C:100142
1485
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1413
If you can't kill the beast, tame it: Tips for surviving WhatsApp® in medical practice
Max S. Mano
Clinics. 2023;78C:100156
1413
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1360
The association of diabetes, subclinical hypothyroidism and carotid intima-media thickness: results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil)
Aída de Melo Spilack, Alessandra C. Goulart, Bianca de Almeida-Pititto, Carolina Castro Porto Silva Janovsky, Paulo A. Lotufo, Itamar de Souza Santos, Isabela M. Benseñor
Clinics. 2023;78C:100154
1360
Highlights

  • cIMT is associated with diabetes.

  • Subclinical hypothyroidism was not associated with cIMT.

  • No additive effect over cIMT was detected in patients with both diseases.

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1322
Results of endoscopic biliary drainage in patients with malignant hilar stricture
Bruno Costa Martins, Caio A. Perez, Jennifer N. Ruas, Luiza H. Bento, Ernesto Q. Mendonça, Gustavo A. de Paulo, Ricardo S. Uemura, Sebastian N. Geiger, ... Fauze Maluf-Filho
Clinics. 2023;78C:100153
1322
Highlights

  • Malignant hilar biliary stricture had a high technical success rate but suboptimal clinical success rate.

  • At multivariable logistic-regression analyses, Bismuth IV strictures were related to higher clinical failure rates when compared to other strictures levels.

  • There was a trend towards higher failure rates with increased levels of pre-drainage bilirubin level, although not statistically significant.

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1294
Will there be a critical review on the malignant transformation of oral lichen planus?
Dante Migliari
Clinics. 2023;78C:100146
1294
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1187
Does bisphenol A (BPA) participates in the pathogenesis of Polycystic Ovary Syndrome (PCOS)?
Lorena Ana Mercedes Lara Urbanetz, José Maria Soares Junior, Gustavo Arantes Rosa Maciel, Ricardo dos Santos Simões, Maria Cândida Pinheiro Baracat, Edmund Chada Baracat
Clinics. 2023;78C:100310
1187
Highlights

  • Bisphenola A (BPA) is an endocrine disruptor widely investigated as a possible environmental contributor to the pathogenesis of Polycystic Ovary Syndrome (PCOS).

  • Due to its structural similarity with the Estrogen molecule (E2), it acts as a xenoestrogen, binding to genomic and non-genomic estrogen receptors, causing metabolic and hormonal changes that lead to PCOS (hyperandrogenism, insulin resistance, hyperinsulinemia, obesity, atherogenic dyslipidemia, anovulation, and ovarian cysts).

  • The aim and of this review were to present the mechanisms of bisphenol A participation in the pathogenesis of Polycystic Ovary Syndrome.

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1184
The effectiveness of ultrasound-guided core needle biopsy in detecting lymph node metastases in the axilla in patients with breast cancer: systematic review and meta-analysis
Qi Xu, Jiale Wang, Jing Wang, Runzhao Guo, Yao Qian, Feng Liu
Clinics. 2023;78C:100207
1184
Highlights

  • US-CNB is a reliable preoperative test for detecting axillary metastasis in breast cancer patients, with high accuracy and safety.

  • Compared to US-FNA, US-CNB shows even higher accuracy for detecting axillary metastasis in breast cancer patients.

  • The use of US-CNB as a preoperative test can reduce the need for a second operation and improve patient outcomes.

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