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9216
The profile of adolescents assisted by the emergency department of a Brazilian private tertiary hospital
Alberto Carame Helito, Ricardo Luiz Affonso Fonseca, Ana Helena D'Arcadia de Siqueira, Carol Machado Ferrer, Guilherme Ramos de Faria, Isabella Rocha Morais, Julio Cesar Arnoni Junior, Mateus de Paiva Breziniscki, Christian Valle Morinaga
Clinics. 2024;79C:100502
9216
Highlights

  • Adolescent particularities are not always considered for consultations at the ED.

  • Flu-like symptoms were the single main reason for adolescents to search for immediate health care.

  • Limb trauma was more common in younger and male teenagers.

  • Acute abdominal pain/trauma were the most frequent causes of hospital admissions.

  • There was a strong correlation between age and both admission rate and severity.

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5611
Visceral crisis in metastatic breast cancer: an old concept with new perspectives
Matheus de Oliveira Andrade, Renata Rodrigues da Cunha Colombo Bonadio, Maria Del Pilar Estevez Diz, Laura Testa
Clinics. 2024;79C:100362
5611
Highlights

  • Visceral crisis in metastatic breast cancer is associated with a dismal prognosis.

  • There is a lack of objective clinical criteria in the definition of visceral crisis.

  • Visceral crisis management is currently based on limited retrospective evidence and expert opinions.

  • The role of chemotherapy as the treatment of choice for visceral crisis has been recently questioned.

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2312
It is time to change the definition: Endometriosis is no longer a pelvic disease
Maria Carolina Machado da Silva, Luiz Philipe de Souza Ferreira, Amanda Della Giustina
Clinics. 2024;79C:100326
2312
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2128
Homeopathy is not placebo effect: proof of the scientific evidence for homeopathy in open access trilingual e-book
Marcus Zulian Teixeira
Clinics. 2024;79C:100456
2128
Highlights

  • Homeopathy is based on four heterodox and complementary scientific assumptions.

  • Pseudoskeptics deny these assumptions and any scientific evidence that proves them.

  • The e-book proves the scientific evidence for homeopathy.

  • The e-book describes hundreds of experimental and clinical studies in homeopathy.

  • The e-book demystifies the fallacy that “homeopathy is placebo effect”.

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2032
Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity
Jamila Al-Zadjali, Amal Al-Lawati, Nafila Al Riyami, Koukab Al Farsi, Najwa Al Jarradi, Ammar Boudaka, Ali Al Barhoumi, Mohsen Al Lawati, ... Jumana Saleh
Clinics. 2024;79C:100344
2032
Highlights

  • Low HDL-C and high ferritin are linked to increased Long-COVID-19 severity.

  • Changes in HDL-C levels, significantly impact Long-COVID-19 progression.

  • Ferritin may exacerbate disease progression by increasing oxidative stress.

  • HDL-C and ferritin levels may serve as markers and therapeutic targets for Long-COVID-19.

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1943
Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia
AiLi Xue, Hua Zhang, ShanShan Song, Xia Yu
Clinics. 2024;79C:100476
1943
Highlights

  • NAC combined with AH is effective in treating pneumonia.

  • NAC combined with AH alleviates clinical symptoms of pneumonia.

  • NAC combined with AH reduces inflammatory response in pneumonia.

  • NAC combined with AH improves blood gas and immune function in pneumonia.

  • NAC combined with AH improves lung function in pneumonia.

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1746
Screening and diagnostic tools for autism spectrum disorder: Systematic review and meta-analysis
Clara Lucato dos Santos, Indyanara Inacio Barreto, Idevaldo Floriano, Luca Schiliró Tristão, Antonio Silvinato, Wanderley Marques Bernardo
Clinics. 2024;79C:100323
1746
Highlights

  • Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder.

  • Autism spectrum disorder has a significant impact on the patient and their family.

  • To provide adequate advice is to carry out screening and diagnosis correctly and accurately.

  • Screening test must be applied, M-CHAT-R/F is recommended.

  • For diagnosis CARS and ADOS are the most recommended tools.

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1739
The effects of art therapy interventions on anxiety in children and adolescents: A meta-analysis
Bo Zhang, Jiahua Wang, Azizah binti Abdullah
Clinics. 2024;79C:100404
1739
Highlights

  • This meta-analysis aimed to evaluate the impact of art therapy on reducing anxiety symptoms among children and adolescents. A comprehensive search was conducted across several databases, including PubMed, Web of Science, Embase, PsychINFO, The Cochrane Library, CNKI, and Wan Fang Data, resulting in the inclusion of six studies with a total of 422 participants. The findings demonstrated a significant decrease in anxiety symptoms through art therapy interventions, with a Standardized Mean Difference (SMD) of -1.42, 95% Confidence Interval (-2.33, -0.51), p < 0.002. This indicates that art therapy is an effective method for treating anxiety in this demographic. Moreover, the analysis revealed that art therapy had a more pronounced effect on state anxiety than on trait anxiety, suggesting that art therapy may be particularly beneficial in helping children and adolescents manage anxiety in specific situations. These insights underscore the importance of integrating art therapy into mental health care, especially for managing anxiety among young individuals, and have significant implications for clinical practice and policy making.

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1648
Pharmacological treatment for obstructive sleep apnea: A systematic review and meta-analysis
Maria Luísa Nobre, Ayane Cristine Alves Sarmento, Priscila Farias de Oliveira, Felipe Ferreira Wanderley, José Diniz Júnior, Ana Katherine Gonçalves
Clinics. 2024;79C:100330
1648
Highlights

  • Obstructive sleep apnea affects one billion people worldwide and is associated with cardiometabolic risk and cognitive impairment.

  • Drug therapy for the management of sleep apnea has been investigated, but no robust evidence that supports its benefits has been found to date.

  • The combination of noradrenergic and antimuscarinic drugs shows promising results.

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1409
Physicians’ attention to patients’ communication cues can improve patient satisfaction with care and perception of physicians’ empathy
Carlos Frederico Confort Campos, Clarice Rosa Olivo, Milton de Arruda Martins, Patricia Zen Tempski
Clinics. 2024;79C:100377
1409
Highlights

  • • Patient-doctor communication relates to patient satisfaction and perceived empathy.

  • • Patients asking questions was linked to poor satisfaction and empathy perceptions.

  • • Doctor's use of negative communication skills related to worse rapport with patients.

  • • Satisfaction and empathy are positively linked to patient affective expression.

  • • Doctors providing advice/suggestions positively correlated to patient satisfaction.

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1386
Low back pain, pelvic pain, and associated factors in type 1 diabetic pregnant women
Patricia Andrade Batista, Cláudia de Oliveira, Rafaela Alkmin da Costa, Rossana Pulcineli Vieira Francisco, Fabio Roberto Cabar
Clinics. 2024;79C:100325
1386
Highlights

  • DM1 is associated with changes in skeletal muscle functionality.

  • During pregnancy, the incidence of low back pain and pelvic pain is moderate and the presence of DM1 may be associated with the early appearance of this symptom.

  • The study demonstrated that pregnant women with DM1 complain of pain with a moderate incidence in the second trimester of pregnancy.

  • Factors such as length of illness are related to the higher frequency of pain in pregnant women with DM1.

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1359
Low-level red-light therapy for myopia control in children: A systematic review and meta-analysis
Dillan Cunha Amaral, Sávio Batista, Edson dos Santos-Neto, José Eduardo Ferreira Manso, Márcio Penha Morterá Rodrigues, Mário Luiz Ribeiro Monteiro, Milton Ruiz Alves, Ricardo Noguera Louzada
Clinics. 2024;79C:100375
1359
Highlights

  • There is a global increase in childhood myopia and current treatments are limited.

  • LLRL non-invasive therapy shows promise in myopia control.

  • LLRL is promising and requires further studies for standardization and safety.

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1267
Cross-cultural adaptation of the Scale of Perception of Respect for and Maintenance of the Dignity of the Inpatient (CuPDPH) to Brazilian Portuguese and its psychometric properties—A multicenter cross-sectional study
Pablo Eduardo Pereira Dutra, Laiana Azevedo Quagliato, Filipe Terra Curupaná, Letícia Zangirolami Peres, Victoria Luiza Pacini, Claudia Regina Menezes da Silva, Juliana Seixas Garcia, Beatriz Campillo Zaragoza, Antonio Egidio Nardi
Clinics. 2024;79C:100328
1267
Highlights

  • Despite their importance, dignity and respect are woefully undefined, and often cast aside, which is reflected by the scarcity of in-depth studies.

  • Brazilian patients feel respected, but when it comes to consideration and integrity, it is nothing short of heartbreaking.

  • Brazilian health professionals do not ask their patients whom they would like to share information with. And this demands our utmost attention.

  • A sting of disrespect and affronts to our dignity seldom escape our notice.

  • The Scale of Perception of Respect for and Maintenance of the Dignity of the Inpatient sheds light on this aspect of human interaction.

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1256
Water pollution and the brain
Fulvio A. Scorza, Feres Chaddad-Neto, Larissa Beltramim, Josef Finsterer, Tomás de la Rosa
Clinics. 2024;79C:100424
1256
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1254
Delayed diagnosis and increased mortality risk: Assessing the effects of the COVID-19 pandemic on breast cancer recurrence
Lindson Mühlmann, Franklin Fernandes Pimentel, Daniel Guimarães Tiezzi, Hélio Humberto Angotti Carrara, Jurandyr Moreira de Andrade, Francisco José Candido dos Reis
Clinics. 2024;79C:100340
1254
Highlights

  • COVID-19 profoundly affected global healthcare including breast cancer management.

  • The pandemic delayed recurrence diagnosis and increased post-recurrence mortality.

  • Strategies for cancer patients' follow-up during health crises need improvements.

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1189
Blood transfusion is correlated with elevated adult all-cause mortality and cardiovascular mortality in the United States: NHANES 1999 to 2018 population-based matched propensity score study
Jie Shi, Min Meng, Rina Sa, Lijun Yu, Yali Lu, Bei Gao
Clinics. 2024;79C:100379
1189
Highlights

  • Blood transfusion significantly impacts long-term all-cause and cardiovascular mortality in the US population.

  • After propensity score-matching, the risk of all-cause mortality increased by 78 % with blood transfusion, and the risk of cardiovascular mortality increased by 102 %.

  • The effective management of blood transfusion in the general population may be beneficial.

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1186
Effect of photobiomodulation therapy on pain perception during anesthetic puncture of dental local anesthesia: A systematic review
Caio Melo Mesquita, Millena Barroso Oliveira, Marcelo Dias Moreira de Assis Costa, Walbert Andrade Vieira, Rafael Rodrigues Lima, Sigmar de Mello Rode, Luiz Renato Paranhos
Clinics. 2024;79C:100322
1186
Highlights

  • Photobiomodulation therapy seems to have little or no effect on pain perception during the anesthetic puncture in patients undergoing dental local anesthesia.

  • Clinical trials found in the literature used different study samples, pain assessment tools, and photobiomodulation therapy protocols.

  • Further randomized studies should be performed with a standardized methodology to strengthen the current evidence.

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1118
Multidisciplinary team for patients with neurocutaneous syndromes: The little discussed importance of dentistry
Marcos Roberto Tovani-Palone, Filippo Bistagnino, Pritik A. Shah
Clinics. 2024;79C:100332
1118
Highlights

  • The inclusion of dentists in multidisciplinary teams for patients with neurocutaneous syndromes is essential, both on an outpatient and hospital basis.

  • Interestingly, dentistry can play a relevant role in the early diagnosis and differential diagnosis of patients with neurocutaneous syndromes.

  • More research in this area is needed.

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1098
The increasing popularity of Peruvian maca (Lepidium meyenii) and its potential impacts on sleep and quality of life
Vinícius Dokkedal-Silva, Priscila Kalil Morelhão, Sergio Tufik, Monica Levy Andersen
Clinics. 2024;79C:100398
1098
Highlights

  • Peruvian maca is a popular supplement consumed to increase energy and sexual health.

  • Studies report it also has anti-sinflammatory and neuroprotective effects.

  • Stimulant properties of this supplement raise questions about its effects on sleep.

  • Investigation of possible reinforcing characteristics is also recommended.

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Are you a health professional able to prescribe or dispense drugs?

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