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Journal Information
Issue
Vol. 80. (In progress)(January - December 2025)
This issue is in progress but contains articles that are final and fully citable.
Original articles
Lactylated histone H3K18 as a potential biomarker for the diagnosis and prediction of the severity of pancreatic cancer
Jinping Hou, Mingsong Guo, Yongqiong Li, Yijin Liao
Highlights
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High level of Pan Lysine Lactylation (Pan-Kla) is found in pancreatic cancer tissues.
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H3K18la levels are increased in pancreatic cancer tissues.
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H3K18la is related to the severity and prognosis of pancreatic cancer.
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The role of hormone dosages in the assessment of cervical lesions by FNA: A descriptive analysis of 762 cases
Arthur Henrique Cunha-Volpato, Carlos Izaias Sartorão Neto, Luiz Fernando Ferraz da Silva, Paulo Campos Carneiro
Highlights
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Hormone measurement in FNA washout fluid is an accessible method for improving accuracy.
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Thyroglobulin (TG) dosage can enhance the accuracy of detecting well-differentiated thyroid carcinomas.
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Calcitonin dosage complements cytology in detecting medullary thyroid carcinoma cervical metastasis.
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Post-thyroidectoby bed dosages help to determine non-thyroid/parathyroid lesions.
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Correlation between liver volume drainage and clinical success after endoscopic biliary drainage of hilar malignant obstruction
Jennifer Nakamura Ruas, Ernesto Quaresma Mendonça, Luciano Lenz, Gustavo Andrade de Paulo, Ricardo Uemura Sato, José Jukemura, Ulysses Ribeiro Junior, Fauze Maluf-Filho, Bruno Costa Martins
Highlights
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The main cause of hilar obstruction was cholangiocarcinoma (32.9 %) followed by lymph node metastasis (23.2 %).
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Technical success was achieved in 91.5 %, clinical success in 60 %.
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A significant correlation between clinical success rate was found when at least 50 % of viable parenchyma was drained (p = 0.016; OR = 4.15, 95 % CI 1.4–12.5).
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Considering liver sectors, higher clinical success rates were found when at least 2 sectors were drained (p < 0.001; OR = 8.50, 95 % CI 2.7–26.7).
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Correlation between unilateral versus bilateral drainage and clinical success was not statistically significant.
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Descriptive study of claims in primary care during the year 2022 in a health area of Spain
María F. Velázquez-López, María García-Pérez, Montserrat Souto-Pereira, Juan M. Vazquez-Lago
Highlights
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Analyzing complaints is essential for identifying areas for improvement.
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79 % of the complaints were related to communication issues with the patient.
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Improving communication with the patient will help reduce the number of complaints filed.
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Using a web application simplifies the management of complaints in primary care.
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Infiltration of micro-fragmented adipose tissue under local anesthesia for knee osteoarthritis treatment is a safe procedure: A case series
Bruno Butturi Varone, Daniel Peixoto Leal, Daniel Duarte Perini, Vitor Penteado Figueiredo Pagotto, Riccardo Gomes Gobbi, Marco Kawwamura Demange
Highlights
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Harvesting abdominal fat for mFAt knee injection is a safe procedure.
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Minor events, such as ecchymosis, mild abdominal discomfort, and mild discomfort at the infiltrated knee are common.
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The procedure can be done under local anesthesia, without sedation after single-time preparation.
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Review articles
Towards optimal management of lower eyelid malpositions: A systematic review of treatment effectiveness and safety
Lana Sbitan, Haneen Tanous, Mira Nawfal Jardak, Cristina Pires Camargo
Highlights
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A comprehensive systematic review was conducted, to provide healthcare workers with a vital resource in the treatment of eyelid malposition, our search spanned electronic databases, clinical trials registries, and relevant journals.
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The study includes 15 selected trials evaluating 709 patients (855 eyelids), with an assessment of trial quality using the Cochrane Risk-of-Bias tool (RoB V2).
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