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Most often read

9710
“Similia Similibus Curentur”: The scientific grounding of the homeopathic therapeutic principle through the systematic study of the rebound effect of modern drugs
Marcus Zulian Teixeira
Clinics. 2022;77C:100091
9710
Highlights

  • Homeopathy employs the principle of therapeutic similitude as a method of treatment.

  • Primary action of drugs is followed by secondary and opposite reaction of the organism.

  • This secondary and opposite reaction of the organism is namely the rebound effect of drugs.

  • Homeopathy employs the rebound effect of drugs in a therapeutic way.

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8463
Medical errors, medical negligence and defensive medicine: A narrative review
Ivan Dieb Miziara, Carmen Silvia Molleis Galego Miziara
Clinics. 2022;77C:100053
8463
HIGHLIGHTS

  • This article defines medical errors and medical responsibility from a Brazilian perspective.

  • This article calls attention to the risks of medical liability and the unethical use of defensive medicine.

  • The authors propose some procedures and attitudes to avoid medical errors like the use of technology at the bedside and computer-based protocols.

  • The authors state that a good and ethical medical practice can avoid medical liability.

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7477
Targeted massively parallel sequencing panel to diagnose genetic endocrine disorders in a tertiary hospital
Amanda M. Narcizo, Lais C. Cardoso, Anna F.F. Benedetti, Alexander A.L. Jorge, Mariana F.A. Funari, Barbara L. Braga, Monica M. Franca, Luciana R. Montenegro, ... Berenice B. Mendonca
Clinics. 2022;77C:100132
7477
Highlights

  • The multigenic panel effectively diagnoses patients with endocrine diseases.

  • It is the first panel to diagnose a broad spectrum of endocrine diseases using TMPS.

  • This panel helps the visualization of molecular pathways behind endocrine conditions.

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5774
Sex differences in Parkinson's Disease: An emerging health question
Luiz Philipe de Souza Ferreira, Rafael André da Silva, Matheus Marques Mesquita da Costa, Vinicius Moraes de Paiva Roda, Santiago Vizcaino, Nilma R.L.L. Janisset, Renata Ramos Vieira, José Marcos Sanches, ... Manuel de Jesus Simões
Clinics. 2022;77C:100121
5774
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5448
A meta-analysis of the effect of Sjögren′s syndrome on adverse pregnancy outcomes
Baoqing Geng, Keyue Zhang, Xianqian Huang, Yong Chen
Clinics. 2022;77C:100140
5448
Highlights

  • Dry syndrome can increase the risk of spontaneous abortion and preterm delivery.

  • Dry syndrome can increase the risk of low birth weight and birth defects.

  • Clinics should provide comprehensive prenatal counseling and testing for the patients.

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5410
Sudden unexpected death in Parkinson's disease: Insights from clinical practice
Fulvio A. Scorza, Marcia Guimarães-Marques, Mariana Nejm, Antônio Carlos G. de Almeida, Carla A. Scorza, Ana C. Fiorini, Josef Finsterer
Clinics. 2022;77C:100001
5410
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5010
Maternal vaccination as an additional approach to improve the protection of the nursling: Anti-infective properties of breast milk
Yingying Zheng, Simone Correa-Silva, Patricia Palmeira, Magda Carneiro-Sampaio
Clinics. 2022;77C:100093
5010
Highlights

  • Human milk is an essential source of immunonutrients for the nursing infant.

  • Maternal vaccination provides specific IgA and IgG antibodies in breast milk.

  • Milk from vaccinated mothers contains anti-SARS-CoV-2 antibodies that may protect the infant.

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4152
Efficacy and safety of potassium-competitive acid blockers versus proton pump inhibitors as Helicobacter pylori eradication therapy: a meta-analysis of randomized clinical trials
Mengran Zhang, Mingge Pang, Mei Zhang
Clinics. 2022;77C:100058
4152
HIGHLIGHTS

  • The efficacy of P-CAB-based triple therapy is superior to that of PPI-based triple therapy as a first-line approach to H. pylori eradication, particularly in Japanese patients.

  • P-CABs were not superior to PPIs as a salvage triple eradication therapy.

  • The safety and tolerability of P-CAB are comparable to PPI in H. pylori triple eradication therapies.

  • Further large RCTs conducted in multiple regions and countries are necessary.

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3789
Hemodynamic depression after carotid surgery: Incidence, risk factors and outcomes
Lauro A.C. Bogniotti, Marcelo P. Teivelis, Francisco A.M. Cardozo, Bruno Caramelli, Nelson Wolosker, Pedro Puech-Leão, Nelson De Luccia, Daniela Calderaro
Clinics. 2022;77C:100090
3789
Highlights

  • Incidence of Hemodynamic Depression was 54.4% in 237 carotid surgeries.

  • Asymptomatic carotid stenosis and endovascular surgery were predictors of HD.

  • Hypotension requiring continuous vasopressor infusion was associated with MACE.

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3743
Cervical cancer screening in low- and middle-income countries: A systematic review of economic evaluation studies
Carmen Phang Romero Casas, Rita de Cássia Ribeiro de Albuquerque, Rafaela Borge Loureiro, Angela Maria Gollner, Marina Gonçalves de Freitas, Graciela Paula do Nascimento Duque, Juliana Yukari Kodaira Viscondi
Clinics. 2022;77C:100080
3743
Highlights

  • Screening and early detection programs are a cornerstone of cervical cancer prevention.

  • Human papillomavirus DNA-based testing reduced the incidence of CC below per capita GDP.

  • Cost-effectiveness of HPV testing versus cytology in Low- and Middle-Income Countries.

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3391
Quality of life in patients with malignant pleural effusion treated with an indwelling pleural catheter in an emerging country
Leticia Leone Lauricella, Paula Duarte D'Ambrosio, Priscila Berenice da Costa, Marcia Cristina Augusto, Paulo Manuel Pêgo-Fernandes, Ricardo Mingarini Terra
Clinics. 2022;77C:100063
3391
Highlights

  • Indwelling pleural catheter represents a suitable option for patients with malignant pleural effusion and short life expectancy. It relieves respiratory symptoms without compromising the quality of life, and the complication rate is low, even in an emerging country, with a low socioeconomic and under-educated patient population. The rate of spontaneous pleurodesis was 45%. The analysis of the visual analog scale showed significant control of dyspnea (p = 0.001), but pain and quality of life did not change significantly.

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3379
Guillain-Barre syndrome related to SARS-CoV-2 vaccinations
Josef Finsterer, Carla A. Scorza, Fulvio A. Scorza
Clinics. 2022;77C:100113
3379
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3223
Comparing dextrose prolotherapy with other substances in knee osteoarthritis pain relief: A systematic review
Vitor Santos Cortez, Walter Augusto Moraes, João Victor Taba, Alberto Condi, Milena Oliveira Suzuki, Fernanda Sayuri do Nascimento, Leonardo Zumerkorn Pipek, Vitoria Carneiro de Mattos, ... Leandro Ryuchi Iuamoto
Clinics. 2022;77C:100037
3223
Highlights

  • Dextrose injections promote deposition of collagen into injured structures through growth factors and inflammatory cells.

  • Dextrose-prolotherapy is a useful treatment method, but it is not superior or inferior to its counterparts.

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2878
Risk factors of transplant renal artery stenosis in kidney transplant recipients
Gabriel Kanhouche, Gustavo Rocha Feitosa Santos, Henry Campos Orellana, Attilio Galhardo, Ana Carolina Buso Faccinetto, Manoela Linhares Machado Barteczko, Luiz Sérgio F. de Carvalho, Julia Bernardi Taddeo, ... Adriano Henrique Pereira Barbosa
Clinics. 2022;77C:100087
2878
Highlights

  • TRAS is the most common vascular complication after kidney transplantation.

  • Delayed graft function increases more than 3 times the chance of developing TRAS.

  • Diabetes mellitus and DGF are independent risk factors for post-anastomotic TRAS.

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2821
Cognitive-behavioral group therapy for women with hypoactive sexual desire: A pilot randomized study
Théo Lerner, Vicente Renato Bagnoli, Elsa Aida Gay de Pereyra, Lucivanda Pontes Fonteles, Isabel Cristina Esposito Sorpreso, José Maria Soares Júnior, Edmund Chada Baracat
Clinics. 2022;77C:100054
2821
Highlights

  • Group cognitive-behavioral therapy (CBT) have a positive influence on women's sexuality.

  • Group CBT was shown to be an effective tool for treating Hypoactive Sexual desire disorder in women.

  • Group CBT can be a short-term focal intervention carried out by gynecologists specialized in sexual health.

  • Group CBT can be used in a high-complexity care setting.

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2801
Is 12 months enough to reach function after athletes’ ACL reconstruction: a prospective longitudinal study
Ellen Cristina Rodrigues Felix, Angelica Castilho Alonso, Guilherme Carlos Brech, Tiago Lazzaretti Fernandes, Adriano Marques de Almeida, Natália Mariana Silva Luna, Jose Maria Soares-Junior, Edmund Chada Baracat, ... Júlia Maria D'Andrea Greve
Clinics. 2022;77C:100092
2801
Highlights

  • Anterior cruciate ligament injury is disabling in several sports.

  • nterior cruciate ligament injury causes knee instability and functional deficit.

  • Usually, surgical treatments produce best functional outcomes.

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2735
Adolescents’ knowledge of HPV and sexually transmitted infections at public high schools in São Paulo: A cross-sectional study
Jose Maria Soares Junior, Hervillin Maria Creusa de Oliveira, Camilla Maganhin Luquetti, Lea Tami Suzuki Zuchelo, Eduardo Carvalho de Arruda Veiga, Juliana Zangirolami Raimundo, Francisco Winter dos Santos Figueiredo, Mayara Souza Alves, ... Edmund Chada Baracat
Clinics. 2022;77C:100138
2735
Highlights

  • Adolescents’ knowledge of HPV.

  • Adolescents’ knowledge of sexually transmitted diseases.

  • Female adolescents’ knowledge of HPV and sexually transmitted diseases.

  • Male adolescents’ knowledge of HPV and sexually transmitted diseases.

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2676
Two decades of liver resection with a multidisciplinary approach in a single institution: What has changed? Analysis of 1409 cases
Paulo Herman, Gilton Marques Fonseca, Fabricio Ferreira Coelho, Jaime Arthur Pirola Kruger, Fabio Ferrari Makdissi, Vagner Birk Jeismann, Flair José Carrilho, Luiz Augusto Carneiro D'Albuquerque, Sergio Carlos Nahas
Clinics. 2022;77C:100088
2676
Highlights

  • Analysis of changes in hepatectomies during the last 2 decades.

  • The surgical treatment of liver tumors needs a multidisciplinary approach.

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2523
Ischemic stroke in 455 COVID-19 patients
Josef Finsterer, Fulvio Alexandre Scorza, Carla Alessandra Scorza, Ana Claudia Fiorini
Clinics. 2022;77C:100012
2523
Highlights

  • Ischemic stroke in COVID-19 is multifactorial but predominantly embolic.

  • Ischemic stroke in COVID-19 predominantly affects males and the anterior circulation.

  • Frequency of ischemic stroke has not increased since the outbreak of the pandemic.

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2515
Cardiopulmonary exercise test in patients with refractory angina: functional and ischemic evaluation
Camila R.A. de Assumpção, Danilo M.L. do Prado, Camila P. Jordão, Luciana O.C. Dourado, Marcelo L.C. Vieira, Carla G. de S.P. Montenegro, Carlos E. Negrão, Luís H.W. Gowdak, Luciana D.N.J. De Matos
Clinics. 2022;77C:100003
2515
Highlights

  • OUES analysis is useful for assessing functional capacity in refractory angina.

  • O2 pulse curve is correlated with contractile alterations in exercise echocardiogram.

  • Cardiopulmonary exercise test is useful toll in patients with refractory angina.

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