Largest Brazilian study analyzing post-transplant outcomes in HCC patients.

Post-transplant overall survival in HCC patients was 63% over five years.

HCC recurrence was observed in 8% of patients submitted to liver transplantation.

Patients within Brazilian expanded criteria had lower survival than Milan Criteria.

Brazilian criteria was inferior to Milan Criteria to predict tumor recurrence.

Patient reported outcomes (PROs) are important to understanding the impact a disease from the patients’ point of view.

Chronic liver disease (CLD) can carry a high clinical and PRO burden.

PRO data are few among patients with CLD who reside in the Latin America and the Caribbean areas.

Using valid and reliable PRO instruments, we quantified PROs for patients with CLD living in Cuba.

We determined that patients from Cuba with hepatitis C virus and autoimmune liver disease had the worst PRO scores most likely related to more severe underlying liver disease (fibrosis) and/or to extrahepatic manifestations (fatigue, abdominal pain, anxiety, and depression).